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Research Output 2009 2019

  • 413 Citations
  • 11 h-Index
  • 27 Article
  • 1 Comment/debate
2019

High accuracy differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma by immunoglobulin G glycosylation

Shih, H. C., Chang, M. C., Chen, C. H., Tsai, I. L., Wang, S. Y., Kuo, Y. P., Chen, C. H. & Chang, Y. T., Jan 3 2019, In : Clinical Proteomics. 16, 1

Research output: Contribution to journalArticle

Open Access
Glycosylation
Pancreatitis
Adenocarcinoma
Immunoglobulin G
Regression Analysis
4 Citations (Scopus)

Metabolome analysis for investigating host-gut microbiota interactions

Chen, M. X., Wang, S. Y., Kuo, C. H. & Tsai, I. L., Mar 2019, In : Journal of the Formosan Medical Association.

Research output: Contribution to journalArticle

Metabolome
Mass Spectrometry
Metabolomics
Dysbiosis
Microbiota

Metastatic colorectal cancer rewrites metabolic program through a Glut3-YAP-dependent signaling circuit

Kuo, C. C., Ling, H. H., Chiang, M. C., Chung, C. H., Lee, W. Y., Chu, C. Y., Wu, Y. C., Chen, C. H., Lai, Y. W., Tsai, I. L., Cheng, C. H. & Lin, C. W., Jan 1 2019, In : Theranostics. 9, 9, p. 2526-2540 15 p.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Neoplasm Metastasis
Colonic Neoplasms
Neoplasms
Proteins
2018
6 Citations (Scopus)

Development of a general method for quantifying IgG-based therapeutic monoclonal antibodies in human plasma using protein G purification coupled with a two internal standard calibration strategy using LC-MS/MS

Chiu, H. H., Liao, H. W., Shao, Y. Y., Lu, Y. S., Lin, C. H., Tsai, I. L. & Kuo, C. H., Jan 1 2018, (Accepted/In press) In : Analytica Chimica Acta.

Research output: Contribution to journalArticle

Calibration
antibody
Purification
purification
Blood Proteins

Method development of immunoglobulin G purification from micro-volumes of human serum for untargeted and targeted proteomics-based antibody repertoire studies

Chang, Y. T., Chang, M. C., Tsai, Y. J., Ferng, C., Shih, H. C., Kuo, Y. P., Chen, C. H. & Tsai, I. L., Jan 1 2018, (Accepted/In press) In : Journal of Food and Drug Analysis.

Research output: Contribution to journalArticle

immunoglobulin G
Proteomics
proteomics
Immunoglobulin G
purification methods
2017
2 Citations (Scopus)

An on-spot internal standard addition approach for accurately determining colistin A and colistin B in dried blood spots using ultra high-performance liquid chromatography–tandem mass spectrometry

Tsai, I. L., Kuo, C. H., Sun, H. Y., Chuang, Y. C., Chepyala, D., Lin, S. W. & Tsai, Y. J., Oct 25 2017, In : Journal of Pharmaceutical and Biomedical Analysis. 145, p. 783-793 11 p.

Research output: Contribution to journalArticle

Colistin
Mass spectrometry
Mass Spectrometry
Blood
Prodrugs
5 Citations (Scopus)

Development of an LC-MS/MS method with protein G purification strategy for quantifying bevacizumab in human plasma

Chiu, H. H., Tsai, I. L., Lu, Y. S., Lin, C. H. & Kuo, C. H., Sep 29 2017, (Accepted/In press) In : Analytical and Bioanalytical Chemistry. p. 1-11 11 p.

Research output: Contribution to journalArticle

Plasma (human)
Purification
Monoclonal Antibodies
Pharmaceutical Preparations
Proteins
3 Citations (Scopus)

Grasping the pseudo-cleft in the case of a small, severely tethered posterior mitral leaflet

Lee, C. W., Sung, S. H., Chang, T. Y., Tsai, I. L., Hsu, C. P. & Shih, C. C., Jul 1 2017, In : Korean Circulation Journal. 47, 4, p. 536-537 2 p.

Research output: Contribution to journalComment/debate

Open Access
2 Citations (Scopus)

Rapid quantification of glutaminase 2 (GLS2)-related metabolites by HILIC-MS/MS

Chen, G. Y., Chao, H. C., Liao, H. W., Tsai, I. L. & Kuo, C. H., Dec 15 2017, In : Analytical Biochemistry. 539, p. 39-44 6 p.

Research output: Contribution to journalArticle

Glutaminase
Metabolites
Glutamine
Glutathione
Glutamic Acid
11 Citations (Scopus)

Sensitive screening of abused drugs in dried blood samples using ultra-high-performance liquid chromatography-ion booster-quadrupole time-of-flight mass spectrometry

Chepyala, D., Tsai, I. L., Liao, H. W., Chen, G. Y., Chao, H. C. & Kuo, C. H., Mar 31 2017, In : Journal of Chromatography A. 1491, p. 57-66 10 p.

Research output: Contribution to journalArticle

Preclinical Drug Evaluations
High performance liquid chromatography
Mass spectrometry
Mass Spectrometry
Screening
2015
12 Citations (Scopus)
Plasma (human)
Colistin
High performance liquid chromatography
Fluorescence
High Pressure Liquid Chromatography
7 Citations (Scopus)
Electrospray ionization
Electrospray Ionization Mass Spectrometry
Liquid chromatography
Metabolites
Tandem Mass Spectrometry
6 Citations (Scopus)

Use of high-conductivity sample solution with sweeping-micellar electrokinetic capillary chromatography for trace-level quantification of paliperidone in human plasma

Liu, H. Y., Hwang, T. J., Tsai, I. L. & Kuo, C. H., Feb 1 2015, In : Electrophoresis. 36, 4, p. 534-542 9 p.

Research output: Contribution to journalArticle

Micellar Electrokinetic Capillary Chromatography
Plasma (human)
Chromatography
Plasmas
Washing
3 Citations (Scopus)

Using the Matrix-Induced Ion Suppression Method for Concentration Normalization in Cellular Metabolomics Studies

Chen, G. Y., Liao, H. W., Tsai, I. L., Tseng, Y. J. & Kuo, C. H., Oct 6 2015, In : Analytical Chemistry. 87, 19, p. 9731-9739 9 p.

Research output: Contribution to journalArticle

Metabolites
Ions
Dilution
Cells
Cytology
2014
9 Citations (Scopus)

A matrix-induced ion suppression method to normalize concentration in urinary metabolomics studies using flow injection analysis electrospray ionization mass spectrometry

Chen, G. Y., Liao, H. W., Tseng, Y. J., Tsai, I-L. & Kuo, C. H., Nov 14 2014, In : Analytica Chimica Acta. 864, p. 21-29 9 p.

Research output: Contribution to journalArticle

Flow Injection Analysis
Electrospray ionization
Metabolomics
Electrospray Ionization Mass Spectrometry
Mass spectrometry
9 Citations (Scopus)
Electrospray ionization
Electrospray Ionization Mass Spectrometry
Liquid chromatography
Liquid Chromatography
Mass spectrometry
13 Citations (Scopus)
Electrospray ionization
Electrospray Ionization Mass Spectrometry
Liquid chromatography
Liquid Chromatography
Mass spectrometry
2013
18 Citations (Scopus)

Metabolomic analysis of complex Chinese remedies: Examples of induced nephrotoxicity in the mouse from a series of remedies containing aristolochic acid

Tsai, D. M., Kang, J. J., Lee, S. S., Wang, S. Y., Tsai, I. L., Chen, G. Y., Liao, H. W., Wei-Chu, L., Kuo, C. H. & Tseng, Y. J., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 263757.

Research output: Contribution to journalArticle

Metabolomics
Aristolochia
aristolochic acid I
Proximal Kidney Tubule
Chinese Traditional Medicine
9 Citations (Scopus)

Metabolomic dynamic analysis of hypoxia in MDA-MB-231 and the comparison with inferred metabolites from transcriptomics data

Tsai, I. L., Kuo, T. C., Ho, T. J., Harn, Y. C., Wang, S. Y., Fu, W. M., Kuo, C. H. & Tseng, Y. J., Jun 2013, In : Cancers. 5, 2, p. 491-510 20 p.

Research output: Contribution to journalArticle

Metabolomics
Gene Expression
Cell Line
Tumor Microenvironment
Gluconeogenesis
22 Citations (Scopus)

Screening and confirmation of 62 drugs of abuse and metabolites in urine by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry

Tsai, I. L., Weng, T. I., Tseng, Y. J., Tan, H. K. L., Sun, H. J. & Kuo, C. H., Nov 2013, In : Journal of Analytical Toxicology. 37, 9, p. 642-651 10 p., bkt083.

Research output: Contribution to journalArticle

Water analysis
Deionized water
High performance liquid chromatography
Street Drugs
Metabolites
9 Citations (Scopus)

Simultaneous detection of single nucleotide polymorphisms and copy number variations in the CYP2D6 gene by multiplex polymerase chain reaction combined with capillary electrophoresis

Liao, H. W., Tsai, I. L., Chen, G. Y., Kuo, C. T., Wei, M. F., Hwang, T. J., Chen, W. J., Shen, L. J. & Kuo, C. H., Feb 6 2013, In : Analytica Chimica Acta. 763, p. 67-75 9 p.

Research output: Contribution to journalArticle

Capillary electrophoresis
Cytochrome P-450 CYP2D6
Multiplex Polymerase Chain Reaction
Polymerase chain reaction
Capillary Electrophoresis
40 Citations (Scopus)

Simultaneous quantification of antimicrobial agents for multidrug-resistant bacterial infections in human plasma by ultra-high-pressure liquid chromatography-tandem mass spectrometry

Tsai, I. L., Sun, H. Y., Chen, G. Y., Lin, S. W. & Kuo, C. H., 2013, In : Talanta. 116, p. 593-603 11 p.

Research output: Contribution to journalArticle

High pressure liquid chromatography
Plasma (human)
Tandem Mass Spectrometry
Anti-Infective Agents
Bacterial Infections
2011
12 Citations (Scopus)

Quantitative determination of isoniazid in biological samples by cation-selective exhaustive injection-sweeping-micellar electrokinetic chromatography

Tsai, I. L., Liu, H. Y., Kuo, P. H., Wang, J. Y., Shen, L. J. & Kuo, C. H., Oct 2011, In : Analytical and Bioanalytical Chemistry. 401, 7, p. 2205-2214 10 p.

Research output: Contribution to journalArticle

Isoniazid
Chromatography
Cations
Buffers
Plasma (human)
16 Citations (Scopus)

Using sweeping-micellar electrokinetic chromatography to determine melamine in food

Wu, W. C., Tsai, I. L., Sun, S. W. & Kuo, C. H., Oct 1 2011, In : Food Chemistry. 128, 3, p. 783-789 7 p.

Research output: Contribution to journalArticle

melamine
Chromatography
chromatography
Food
Screening
2010
89 Citations (Scopus)

Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: A crucial role of AMPK and mTOR pathways

Chiang, P. C., Lin, S. C., Pan, S. L., Kuo, C. H., Tsai, I. L., Kuo, M. T., Wen, W. C., Chen, P. & Guh, J. H., Jan 15 2010, In : Biochemical Pharmacology. 79, 2, p. 162-171 10 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Sirolimus
Hepatocellular Carcinoma
Display devices
Cells
31 Citations (Scopus)

Rapid determination of aristolochic acids I and II in herbal products and biological samples by ultra-high-pressure liquid chromatography-tandem mass spectrometry

Kuo, C. H., Lee, C. W., Lin, S. C., Tsai, I. L., Lee, S. S., Tseng, Y. J., Kang, J. J., Peng, F. C. & Wei-Chu, L., Mar 15 2010, In : Talanta. 80, 5, p. 1672-1680 9 p.

Research output: Contribution to journalArticle

High pressure liquid chromatography
Tandem Mass Spectrometry
Mass spectrometry
High Pressure Liquid Chromatography
Aristolochic Acids
2009
9 Citations (Scopus)

Method development for the determination of teicoplanin in patient serum by solid phase extraction and micellar electrokinetic chromatography

Tsai, I. L., Wu, F. L. L., Gau, C. S. & Kuo, C. H., Jan 15 2009, In : Talanta. 77, 3, p. 1208-1216 9 p.

Research output: Contribution to journalArticle

Teicoplanin
Solid Phase Extraction
Chromatography
Serum
Methicillin
66 Citations (Scopus)

Rapid analysis of melamine in infant formula by sweeping-micellar electrokinetic chromatography

Tsai, I. L., Sun, S. W., Liao, H. W., Lin, S. C. & Kuo, C. H., Nov 20 2009, In : Journal of Chromatography A. 1216, 47, p. 8296-8303 8 p.

Research output: Contribution to journalArticle

Infant Formula
Chromatography
Capillary electrophoresis
melamine
Solid Phase Extraction