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Research Output

  • 804 Citations
  • 18 h-Index
  • 61 Article
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Article
2020

Melatonin Promotes Nerve Regeneration Following End-to-Side Neurorrhaphy by Accelerating Cytoskeletal Remodeling via the Melatonin Receptor-dependent Pathway

Liu, C. H., Chang, H. M., Yang, Y. S., Lin, Y. T., Ho, Y. J., Tseng, T. J., Lan, C. T., Li, S. T. & Liao, W. C., Mar 1 2020, In : Neuroscience. 429, p. 282-292 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

Associations between the phenotype and genotype of MnSOD and catalase in periodontal disease

Lee, C. Y., Chang, C. H., Teng, N. C., Chang, H. M., Huang, W. T. & Huang, Y. K., Aug 30 2019, In : BMC Oral Health. 19, 1, p. 201 201.

Research output: Contribution to journalArticle

Open Access

Plasmon-Activated Water Reduces Amyloid Burden and Improves Memory in Animals with Alzheimer’s Disease

Cheng, C. H., Lin, K. J., Hong, C. T., Wu, D., Chang, H. M., Liu, C. H., Hsiao, I. T., Yang, C. P., Liu, Y. C. & Hu, C. J., Dec 1 2019, In : Scientific Reports. 9, 1, 13252.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

The fungus-derived retinoprotectant theissenolactone C improves glaucoma-like injury mediated by MMP-9 inhibition

Lin, F. L., Cheng, Y. W., Yu, M., Ho, J. D., Kuo, Y. C., Chiou, G. C. Y., Chang, H. M., Lee, T. H. & Hsiao, G., Mar 15 2019, In : Phytomedicine. 56, p. 207-214 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

DSE promotes aggressive glioma cell phenotypes by enhancing HB-EGF/ERBB signaling

Liao, W. C., Liao, C. K., Tsai, Y. H., Tseng, T. J., Chuang, L. C., Lan, C. T., Chang, H. M. & Liu, C. H., Jun 1 2018, In : PLoS One. 13, 6, e0198364.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Low Second-to-Fourth Digit Ratio has High Explosive Power? A Prepubertal Study

Hsu, C-C., Fong, T-H., Chang, H-M., Su, B., Chi, C-P., Kan, N-W. & Hsu, M-C., Jul 1 2018, In : Journal of Strength and Conditioning Research. 32, 7, p. 2091-2095 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Masticatory hypofunction effects induced by BTXA injection of hippocampal neurons in developing rats

Tsai, C. Y., Lee, H. P., Chang, H. M. & Wu, F. C., Dec 1 2018, In : Archives of Oral Biology. 96, p. 122-129 8 p.

Research output: Contribution to journalArticle

Plasmon-activated water effectively relieves hepatic oxidative damage resulting from chronic sleep deprivation

Chen, H-C., Cheng, C-Y., Chen, L-Y., Chang, C-C., Yang, C-P., Mai, F-D., Liao, W-C., Chang, H-M. & Liu, Y-C., 2018, In : RSC Advances. 8, 18, p. 9618-9626 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Prophylactic supplement with melatonin successfully suppresses the pathogenesis of periodontitis through normalizing RANKL/OPG ratio and depressing the TLR4/MyD88 signaling pathway

Renn, T. Y., Huang, Y. K., Feng, S. W., Wang, H. W., Lee, W. F., Lin, C. T., Burnouf, T., Chen, L. Y., Kao, P. F. & Chang, H. M., Apr 1 2018, In : Journal of Pineal Research. 64, 3, e12464.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Theissenolactone C exhibited ocular protection of endotoxin-induced uveitis by attenuating ocular inflammatory responses and glial activation

Lin, F. L., Ho, J. D., Cheng, Y. W., Chiou, G. C. Y., Yen, J. L., Chang, H. M., Lee, T. H. & Hsiao, G., Apr 9 2018, In : Frontiers in Pharmacology. 9, APR, 326.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017
20 Citations (Scopus)

Poly-Methyl Methacrylate/Polyvinyl Alcohol Copolymer Agents Applied on Diabetic Wound Dressing

Hsieh, H. T., Chang, H. M., Lin, W. J., Hsu, Y. T. & Mai, F. D., Dec 1 2017, In : Scientific Reports. 7, 1, 9531.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Rearrangement of potassium ions and Kv1.1/Kv1.2 potassium channels in regenerating axons following end-to-end neurorrhaphy: ionic images from TOF-SIMS

Liu, C. H., Chang, H. M., Wu, T. H., Chen, L. Y., Yang, Y. S., Tseng, T. J. & Liao, W. C., Apr 12 2017, (Accepted/In press) In : Histochemistry and Cell Biology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Tailor-made purified human platelet lysate concentrated in neurotrophins for treatment of Parkinson's disease

Chou, M. L., Wu, J. W., Gouel, F., Jonneaux, A., Tillerman, K., Renn, T. Y., Laloux, C., Chang, H. M., Lin, L. T., Devedjian, J. C., Devos, D. & Burnouf, T., Oct 1 2017, In : Biomaterials. 142, p. 77-89 13 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
18 Citations (Scopus)
2016

Redistribution of Cav2.1 channels and calcium ions in nerve terminals following end-to-side neurorrhaphy: ionic imaging analysis by TOF–SIMS

Liu, C. H., Chang, H. M., Tseng, T. J., Lan, C. T., Chen, L. Y., Youn, S. C., Lee, J. J., Mai, F. D., Chou, J. F. & Liao, W. C., 2016, In : Histochemistry and Cell Biology. p. 1-10 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2015

Ceftriaxone prevents and reverses behavioral and neuronal deficits in an MPTP-induced animal model of Parkinson's disease dementia

Hsu, C. Y., Hung, C. S., Chang, H. M., Liao, W. C., Ho, S. C. & Ho, Y. J., 2015, In : Neuropharmacology. 91, p. 43-56 14 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
7 Citations (Scopus)

Early-life sleep deprivation persistently depresses melatonin production and bio-energetics of the pineal gland: potential implications for the development of metabolic deficiency

Chen, L. Y., Tiong, C., Tsai, C. H., Liao, W. C., Yang, S. F., Youn, S. C., Mai, F-D. & Chang, H-M., Mar 1 2015, In : Brain Structure and Function. 220, 2, p. 663-676 14 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
1 Citation (Scopus)

β-1,4-galactosyltransferase III suppresses extravillous trophoblast invasion through modifying β1-integrin glycosylation

Liao, W. C., Liu, C. H., Chen, C. H., Hsu, W. M., Liao, Y. Y., Chang, H. M., Lan, C. T., Huang, M. C. & Shyu, M. K., Apr 1 2015, In : Placenta. 36, 4, p. 357-364 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2014

Proliferative effects of melatonin on Schwann cells: Implication for nerve regeneration following peripheral nerve injury

Chang, H. M., Liu, C. H., Hsu, W. M., Chen, L. Y., Wang, H. P., Wu, T. H., Chen, K. Y., Ho, W. H. & Liao, W. C., 2014, In : Journal of Pineal Research. 56, 3, p. 322-332 11 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2013

Diagnostic performance of procalcitonin for hospitalised children with acute pyelonephritis presenting to the paediatric emergency department

Chen, S. M., Chang, H. M., Hung, T. W., Chao, Y. H., Tsai, J. D., Lue, K. H. & Sheu, J. N., May 2013, In : Emergency medicine journal : EMJ. 30, 5, p. 406-410 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Neuregulin Facilitates Nerve Regeneration by Speeding Schwann Cell Migration via ErbB2/3-Dependent FAK Pathway

Chang, H. M., Shyu, M. K., Tseng, G. F., Liu, C. H., Chang, H. S., Lan, C. T., Hsu, W. M. & Liao, W. C., Jan 2 2013, In : PLoS One. 8, 1, e53444.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Resveratrol suppresses calcium-mediated microglial activation and rescues hippocampal neurons of adult rats following acute bacterial meningitis

Sheu, J. N., Liao, W. C., Wu, U. I., Shyu, L. Y., Mai, F-D., Chen, L. Y., Chen, M. J., Youn, S. C. & Chang, H-M., Mar 2013, In : Comparative Immunology, Microbiology and Infectious Diseases. 36, 2, p. 137-148 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2012

A 12-year-old boy with an infected ectopic ureter presenting with acute appendicitis-like symptoms and acute scrotum

Chu, W. Y., Tsao, T. F., Chen, S. L., Chang, H. M., Chen, S. M., Chen, C. Y., Lue, K. H. & Sheu, J. N., Jun 2012, In : Scandinavian Journal of Urology and Nephrology. 46, 3, p. 208-211 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Bladder agenesis and bilateral ectopic ureters draining into the vagina in a female infant: Demonstrated by MR imaging

Chen, C. Y., Tsao, T. F., Chang, H. M., Chen, S. L., Chen, S. M., Hung, T. W., Lue, K. H. & Sheu, J. N., Jan 2012, In : Surgical and Radiologic Anatomy. 34, 1, p. 89-92 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Blockade of metabotropic glutamate receptors inhibits cognition and neurodegeneration in an MPTP-induced Parkinson's disease rat model

Hsieh, M. H., Ho, S. C., Yeh, K. Y., Pawlak, C. R., Chang, H. M., Ho, Y. J., Lai, T. J. & Wu, F. Y., Jul 2012, In : Pharmacology Biochemistry and Behavior. 102, 1, p. 64-71 8 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Expression of GALNT2 in human extravillous trophoblasts and its suppressive role in trophoblast invasion

Liao, W. C., Chen, C. H., Liu, C. H., Huang, M. J., Chen, C. W., Hung, J. S., Chou, C. H., Chen, C. H., Che, M. I., Chang, H. M., Lan, C. T., Huang, H. C., Tseng, G. F., Shyu, M. K. & Huang, M. C., Dec 2012, In : Placenta. 33, 12, p. 1005-1011 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Life-threatening rhabdomyolysis induced by streptococcus bovis sepsis in a 6-year-old girl presented to the pediatric emergency department

Pan, H. H., Chang, H. M., Chen, S. M., Hung, T. W., Lue, K. H. & Sheu, J. N., May 2012, In : Pediatric Emergency Care. 28, 5, p. 469-471 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Obstructive jaundice activates nitroxidergic neurons of the vago-vagal neural circuit that regulates the hepatobiliary system in rabbits

Hu, M. E., Lin, Y. C., Chang, H. M., Tyan, Y. S. & Lan, C. T., Feb 2012, In : Cells Tissues Organs. 195, 3, p. 272-286 15 p.

Research output: Contribution to journalArticle

Sleep deprivation impairs Ca2+ expression in the hippocampus: Ionic imaging analysis for cognitive deficiency with TOF-SIMS

Chang, H. M., Liao, W. C., Sheu, J. N., Chang, C. C., Lan, C. T. & Mai, F. D., Jun 2012, In : Microscopy and Microanalysis. 18, 3, p. 425-435 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2011

Melatonin inhibits microglial activation, reduces pro-inflammatory cytokine levels, and rescues hippocampal neurons of adult rats with acute Klebsiella pneumoniae meningitis

Wu, U. I., Mai, F-D., Sheu, J. N., Chen, L. Y., Liu, Y. T., Huang, H. C. & Chang, H-M., Mar 2011, In : Journal of Pineal Research. 50, 2, p. 159-170 12 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Multicystic dysplastic kidney disease presenting with a single large cyst in a fetus-anatomical basis and radiological aspects

Lim, F. F., Tsao, T. F., Chang, H. M. & Sheu, J. N., Aug 2011, In : Pediatrics and Neonatology. 52, 4, p. 227-231 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Pneumococcal pneumonia complicating purulent pericarditis in a previously healthy girl: A rare yet possible fatal complication in the antibiotic era

Lim, F. F., Chang, H. M., Lue, K. H. & Sheu, J. N., Aug 2011, In : Pediatric Emergency Care. 27, 8, p. 751-753 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

The role of procalcitonin for acute pyelonephritis and subsequent renal scarring in infants and young children

Sheu, J. N., Chang, H. M., Chen, S. M., Hung, T. W. & Lue, K. H., Nov 2011, In : Journal of Urology. 186, 5, p. 2002-2008 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2010

Impaired sodium levels in the suprachiasmatic nucleus are associated with the formation of cardiovascular deficiency in sleep-deprived rats

Chang, H. M., Mai, F. D., Lei, S. L. & Ling, Y. C., Dec 2010, In : Journal of Anatomy. 217, 6, p. 694-704 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Molecular imaging of in vivo calcium ion expression in area postrema of total sleep deprived rats: Implications for cardiovascular regulation by TOF-SIMS analysis

Mai, F. D., Chen, L. Y., Ling, Y. C., Chen, B. J., Wu, U. I. & Chang, H. M., May 1 2010, In : Applied Surface Science. 256, 14, p. 4456-4461 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2009

Melatonin preserves longevity protein (sirtuin 1) expression in the hippocampus of total sleep-deprived rats

Chang, H. M., Wu, U. I. & Lan, C. T., Oct 2009, In : Journal of Pineal Research. 47, 3, p. 211-220 10 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Ultrastructural observations on the progress of nerve degeneration and regeneration at the suture site following vagal-hypoglossal nerve coaptation in cats

Hu, M. E., Tyan, Y. S., Hsu, P. W., Hsu, J. C., Chang, H. M., Ling, E. A. & Lan, C. T., Sep 2009, In : Cells Tissues Organs. 190, 4, p. 230-245 16 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2008

Calcium/calmodulin-dependent kinase II mediates NO-elicited PKG activation to participate in spinal reflex potentiation in anesthetized rats

Chen, G. D., Peng, M. L., Wang, P. Y., Lee, S. D., Chang, H. M., Pan, S. F., Chen, M. J., Tung, K. C., Lai, C. Y. & Lin, T. B., Feb 2008, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 294, 2

Research output: Contribution to journalArticle

11 Citations (Scopus)

Melatonin preserves superoxide dismutase activity in hypoglossal motoneurons of adult rats following peripheral nerve injury

Chang, H. M., Huang, Y. L., Lan, C. T., Wu, U. I., Hu, M. E. & Youn, S. C., Mar 2008, In : Journal of Pineal Research. 44, 2, p. 172-180 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Mild hypoxic preconditioning attenuates injury-induced NADPH-d/nNOS expression in brainstem motor neurons of adult rats

Wei, I. H., Huang, C. C., Tseng, C. Y., Chang, H. M., Tu, H. C., Tsai, M. H., Wen, C. Y. & Shieh, J. Y., Jan 2008, In : Journal of Chemical Neuroanatomy. 35, 1, p. 123-132 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Molecular imaging of enhanced Na+ expression in the liver of total sleep deprived rats by TOF-SIMS

Chang, H. M., Chen, B. J., Wu, U. I., Huang, Y. L. & Mai, F. D., Dec 15 2008, In : Applied Surface Science. 255, 4, p. 1131-1134 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Orexin-A modulates glutamatergic NMDA-dependent spinal reflex potentiation via inhibition of NR2B subunit

Peng, H. Y., Chang, H. M., Chang, S. Y., Tung, K. C., Lee, S. D., Chou, D., Lai, C. Y., Chiu, C. H., Chen, G. D. & Lin, T. B., Jul 2008, In : American Journal of Physiology - Endocrinology and Metabolism. 295, 1

Research output: Contribution to journalArticle

20 Citations (Scopus)

Sleep deprivation predisposes liver to oxidative stress and phospholipid damage: A quantitative molecular imaging study

Chang, H. M., Mai, F. D., Chen, B. J., Wu, U. I., Huang, Y. L., Lan, C. T. & Ling, Y. C., Mar 2008, In : Journal of Anatomy. 212, 3, p. 295-305 11 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

TRPV1 mediates the uterine capsaicin-induced NMDA NR2B-dependent cross-organ reflex sensitization in anesthetized rats

Peng, H. Y., Chang, H. M., Lee, S. D., Huang, P. C., Chen, G. D., Lai, C. H., Lai, C. Y., Chiu, C. H., Tung, K. C. & Lin, T. B., Nov 2008, In : American Journal of Physiology - Renal Physiology. 295, 5

Research output: Contribution to journalArticle

25 Citations (Scopus)

Up-regulation of Na+ expression in the area postrema of total sleep deprived rats by TOF-SIMS analysis

Mai, F. D., Chen, B. J., Ling, Y. C., Wu, U. I., Huang, Y. L. & Chang, H. M., Dec 15 2008, In : Applied Surface Science. 255, 4, p. 1135-1138 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2007
5 Citations (Scopus)
2006

Total sleep deprivation inhibits the neuronal nitric oxide synthase and cytochrome oxidase reactivities in the nodose ganglion of adult rats

Chang, H. M., Wu, U. I., Lin, T. B., Lan, C. T., Chien, W. C., Huang, W. L. & Shieh, J. Y., Aug 2006, In : Journal of Anatomy. 209, 2, p. 239-250 12 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)