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Hsueh-Yun Lee

Associate Professor

 https://orcid.org/0000-0001-6683-0726
  • 663 Citations
  • 16 h-Index
20092020

Research output per year

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Personal profile

Education

  • 2010 Ph.D. (Pharmaceutical Sciences), National Taiwan University
  • 2001 B.S., School of Pharmacy, Taipei Medical University

Experience

  • 2018- 臺北醫學大學藥物科學學科副教授
  • 2016-2017 臺北醫學大學生技醫療產業研發博士學位學程助理教授
  • 2015-2018 臺北醫學大學藥物科學學科助理教授
  • 2013-2015 臺北醫學大學藥物科學學科專案助理教授
  • 2012-2013 臺北醫學大學藥物科學學科助理研究員
  • 2011-2012 臺北醫學大學博士後研究
  • 2010-2011 國立清華大學博士後研究

Research Interests

  • 藥物化學
  • 藥物合成開發
  • 藥物結構修飾
  • 有機化學合成
  • 天然物全合成

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Projects

結構優化以開發DYRK1B抑制劑

Lee, H.

1/1/20 → 12/31/20

Project: A - Government Institution › d - Ministry of Education

Development of 1,3-Diaryl-Substituted Five-Membered Heterocycles as Anti-Pancreatic Cancer Agents(1/3)

Lee, H.

8/1/19 → 7/31/20

Project: A - Government Institution › b - Ministry of Science and Technology

108大專生計畫獎-李學耘

Lee, H.

8/1/19 → 7/31/20

Project: A - Government Institution › b - Ministry of Science and Technology

設計與合成benzimidazole衍生物作為改善神經退化疾病之化合物

Lee, H.

7/1/19 → 2/1/20

Project: A - Government Institution › b - Ministry of Science and Technology

Research Output

  • 663 Citations
  • 16 h-Index
  • 44 Article
  • 2 Review article

HDAC inhibitor protects chronic cerebral hypoperfusion and oxygen-glucose deprivation injuries via H3K14 and H4K5 acetylation-mediated BDNF expression

Fang, Y-C., Chan, L., Liou, J-P., Tu, Y-K., Lai, M-J., Chen, C-I., Vidyanti, A. N., Lee, H-Y. & Hu, C-J., May 6 2020, In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journal › Article

Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment

Kaur, N., Fang, Y. C., Lee, H. Y., Singh, A., Nepali, K., Lin, M. H., Yeh, T. K., Lai, M. J., Chan, L., Tu, Y. K., Banerjee, S., Hu, C. J. & Liou, J. P., Feb 1 2020, In : European Journal of Medicinal Chemistry. 187, 111915.

Research output: Contribution to journal › Article

    • Synthesis and biological evaluation of 2-quinolineacrylamides

    Wang, S. W., Lin, M. H., Hsu, F. C., Chen, M. C., Liou, J. P., Liu, Y. T., Chen, S. S. & Lee, H. Y., Feb 1 2020, In : Bioorganic and Medicinal Chemistry. 28, 3, p. 115250 115250.

    Research output: Contribution to journal › Article

    • 1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

    Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

    Research output: Contribution to journal › Article

    • 5 Citations (Scopus)

    Nitro-Group-Containing Drugs

    Nepali, K., Lee, H. Y. & Liou, J. P., Mar 28 2019, In : Journal of Medicinal Chemistry. 62, 6, p. 2851-2893 43 p.

    Research output: Contribution to journal › Review article

    • 46 Citations (Scopus)