Hsueh-Yun Lee

Personal profile

Education

Ph.D. (Pharmaceutical Sciences), National Taiwan University

Research Interests

藥物化學
藥物合成開發
藥物結構修飾
有機化學合成
天然物全合成

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9 Similar Profiles

Histone Deacetylase Inhibitors Medicine & Life Sciences

Tubulin Medicine & Life Sciences

Histone Deacetylases Medicine & Life Sciences

Tubulin Modulators Medicine & Life Sciences

Inhibitory Concentration 50 Medicine & Life Sciences

Antineoplastic Agents Medicine & Life Sciences

Neoplasms Medicine & Life Sciences

Cells Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

108大專生計畫獎-李學耘

Lee, H.

8/1/19 → 7/1/20

Project: A - Government Institution › b - Ministry of Science and Technology

開發1,3-二芳基取代之五元雜環作為抗胰臟癌劑(1/3)

Lee, H.

8/1/19 → 7/1/20

Project: A - Government Institution › b - Ministry of Science and Technology

設計與合成benzimidazole衍生物作為改善神經退化疾病之化合物

Lee, H.

7/1/19 → 2/1/20

Project: A - Government Institution › b - Ministry of Science and Technology

Research Output 2009 2019

589 Citations
15 h-Index
41 Article
2 Review article

5 Citations (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journal › Article

Benzamides

Histone Deacetylases

Tubulin

Heterografts

Inhibitory Concentration 50

27 Citations (Scopus)

Nitro-Group-Containing Drugs

Nepali, K., Lee, H. Y. & Liou, J. P., Mar 28 2019, In : Journal of Medicinal Chemistry. 62, 6, p. 2851-2893 43 p.

Research output: Contribution to journal › Review article

Antitubercular Agents

Antiparasitic Agents

Pharmaceutical Chemistry

Prodrugs

Therapeutic Uses

Structure-guided design of anti-cancer ribonucleotide reductase inhibitors

Misko, T. A., Liu, Y. T., Harris, M. E., Oleinick, N. L., Pink, J., Lee, H. Y. & Dealwis, C. G., Jan 1 2019, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 34, 1, p. 438-450 13 p.

Research output: Contribution to journal › Article

Ribonucleotide Reductases

Hydrazones

Neoplasms

Pancreatic Neoplasms

Catalytic Domain

14 Citations (Scopus)

(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo

Lee, H. Y., Nepali, K., Huang, F. I., Chang, C. Y., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 905-917 13 p.

Research output: Contribution to journal › Article

Quinolines

Histone Deacetylase Inhibitors

Multiple Myeloma

Growth

Hydroxamic Acids

10 Citations (Scopus)

5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes

Lee, H. Y., Fan, S. J., Huang, F. I., Chao, H. Y., Hsu, K. C., Lin, T. E., Yeh, T. K., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Jan 29 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journal › Article

tau Proteins

Histone Deacetylase Inhibitors

Alzheimer Disease

Hydroxamic Acids

Phenotype