Research Output per year
Personal profile
Education
- Ph.D. in Pharmaceutical Sciences, National Taiwan University
Research Interests
- 藥物化學
- 藥物合成開發
- 藥物結構修飾
- 有機化學合成
- 天然物全合成
Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 11 Similar Profiles
Histone Deacetylase Inhibitors
Medicine & Life Sciences
Tubulin
Medicine & Life Sciences
Histone Deacetylases
Medicine & Life Sciences
Tubulin Modulators
Medicine & Life Sciences
Inhibitory Concentration 50
Medicine & Life Sciences
Antineoplastic Agents
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Cells
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2009 2019
1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase
Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.Research output: Contribution to journal › Article
Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
Structure-guided design of anti-cancer ribonucleotide reductase inhibitors
Misko, T. A., Liu, Y. T., Harris, M. E., Oleinick, N. L., Pink, J., Lee, H. Y. & Dealwis, C. G., Jan 1 2019, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 34, 1, p. 438-450 13 p.Research output: Contribution to journal › Article
Ribonucleotide Reductases
Hydrazones
Neoplasms
Pancreatic Neoplasms
Catalytic Domain
(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo
Lee, H. Y., Nepali, K., Huang, F. I., Chang, C. Y., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 905-917 13 p.Research output: Contribution to journal › Article
Quinolines
Histone Deacetylase Inhibitors
Multiple Myeloma
Growth
Hydroxamic Acids
5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes
Lee, H. Y., Fan, S. J., Huang, F. I., Chao, H. Y., Hsu, K. C., Lin, T. E., Yeh, T. K., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Jan 29 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.Research output: Contribution to journal › Article
tau Proteins
Histone Deacetylase Inhibitors
Alzheimer Disease
Hydroxamic Acids
Phenotype
A novel dual HDAC6 and tubulin inhibitor, MPT0B451, displays anti-tumor ability in human cancer cells in vitro and in vivo
Wu, Y. W., Hsu, K. C., Lee, H. Y., Huang, T. C., Lin, T. E., Chen, Y. L., Sung, T. Y., Liou, J. P., Hwang-Verslues, W. W., Pan, S. L. & HuangFu, W. C., Mar 13 2018, In : Frontiers in Pharmacology. 9, MAR, 205.Research output: Contribution to journal › Article
Tubulin Modulators
Histone Deacetylases
Neoplasms
Tubulin
Molecular Docking Simulation