Projects per year
Personal profile
Education
- 1996 Dr.rer.nat., Institute of Pharmacy, University of Regensburg, Germany
- 1987 Master, Institute of Pharmacy, National Defense Medical Center
- 1985 Bachelor, School of Pharmacy, National Defense Medical Center
Experience
- 2019- Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2018- Professor, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2018- Professor, Graduate Institute of Nanomedicine and Medical Engineering, Taipei Medical University
- 2016-2017 Professor,Ph.D. Program in Biotechnology Research and Development, Taipei Medical University.
- 2014-2018 Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University.
- 2013-2014 Professor, Department of Pharmaceutical Sciences, Taipei Medical University.
- 2013-2013 Professor, School of Pharmacy, Taipei Medical University.
- 2006-2007 Professor, Graduate Institute of Pharmacognosy, Taipei Medical University.
- 2002-2006 Associate Professor, Graduate Institute of Pharmacognosy, Taipei Medical University.
Awards
- Editorial Board:
- International Journal of Advanced Chemistry (IJAC)
- International Journal of Organic Chemistry
- Der Pharma Chemica
- Journal of Chemical Science and Technology
- Advances in Organic Chemistry (AOC)
- Journal of Bone Marrow and Stem Cell Research
- Journal of Natural Products Research Updates
- Innovational: Journal of Chemistry (IJChem)
- International Journal of Biological Instrumentation
- Asian Council of Science
- Editorial Advisory Board:
- The Open Cancer Journal (ISSN: 1874-0790)
- Recent Patent Reviews on Anti-cancer Drug Discovery
- Outstanding reviewer:
- Outstanding reviewer: Bioorganic & Medicinal Chemistry
- Outstanding reviewer: European Journal of Medicinal Chemistry
Research Interests
- New drugs discovery and development
- Medicinal chemistry
- Discovery of novel anticancer drugs
- Discovery of novel anti-inflammatory drugs
URL
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Network
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Projects
利用人工智能與機器學習模式開發新型多靶點抗癌藥物的新發展策略
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
基於片段的藥物探索方法開發新一類抗癌標靶小分子激酶抑制劑(2/2)
8/1/18 → 7/1/19
Project: A - Government Institution › b - Ministry of Science and Technology
基於片段的藥物探索方法開發新一類抗癌標靶小分子激酶抑制劑(1/2)
8/1/17 → 7/31/18
Project: A - Government Institution › b - Ministry of Science and Technology
Development of Novel Tetracyclic and Heterocyclic Dual Topoisomerases Inhibitors as Anticancer Agents( II )
8/1/16 → 7/31/17
Project: A - Government Institution › b - Ministry of Science and Technology
Development of Novel Tetracyclic and Heterocyclic Dual Topoisomerases Inhibitors as Anticancer Agents( I )
8/1/15 → 7/31/16
Project: A - Government Institution › b - Ministry of Science and Technology
Research Output
A novel salicylanilide derivative induces autophagy cell death in castration-resistant prostate cancer via ER stress-activated PERK signaling pathway
Hsieh, C-L., Huang, H-S., Chen, K-C., Saka, T., Chiang, C-Y., Chung, L. W. K. & Sung, S-Y., Jan 1 2020, In : Molecular Cancer Therapeutics. 19, 1, p. 101-111 11 p.Research output: Contribution to journal › Article
1
Citation
(Scopus)
CC12 induces apoptotic cell death and cell cycle arrest in human glioblastoma cell lines and mouse xenograft model
Fann, L. Y., Shih, J. H., Tseng, J. H., Huang, H. S. & Hsiao, S. H., Apr 2020, In : Molecules. 25, 8, 25081793.Research output: Contribution to journal › Article
Open Access
Temporal expression patterns of distinct cytokines and M1/M2 macrophage polarization regulate rheumatoid arthritis progression
Kung, C. C., Dai, S. P., Chiang, H., Huang, H. S. & Sun, W. H., Jan 1 2020, (Accepted/In press) In : Molecular Biology Reports.Research output: Contribution to journal › Article
γ-Mangostin isolated from Garcinia mangostana L. suppresses inflammation and alleviates symptoms of osteoarthritis via modulating miR-124-3p/IL-6/NF-κB signaling
Chiu, Y-S., Wu, J-L., Yeh, C-T., Yadav, V. K., Huang, H-S. & Wang, L-S., Apr 16 2020, In : Aging. 12, 8, p. 6630-6643 14 p.Research output: Contribution to journal › Article
A novel multi-target small molecule, LCC-09, inhibits stemness and therapy-resistant phenotypes of glioblastoma cells by increasing MIR-34a and deregulating the DRD4/AKT/MTOR signaling axis
Wen, Y. T., Wu, A. T., Bamodu, O. A., Wei, L., Lin, C. M., Yen, Y., Chao, T. Y., Mukhopadhyay, D., Hsiao, M. & Huang, H. S., Oct 1 2019, In : Cancers. 11, 10, 1442.Research output: Contribution to journal › Article
Open Access