Projects per year
Personal profile
Education
- 1996 Dr.rer.nat., Institute of Pharmacy, University of Regensburg, Germany
- 1987 Master, Institute of Pharmacy, National Defense Medical Center
- 1985 Bachelor, School of Pharmacy, National Defense Medical Center
Experience
- 2019- Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2018- Professor, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2018- Professor, Graduate Institute of Nanomedicine and Medical Engineering, Taipei Medical University
- 2016-2017 Professor,Ph.D. Program in Biotechnology Research and Development, Taipei Medical University.
- 2014-2018 Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University.
- 2013-2014 Professor, Department of Pharmaceutical Sciences, Taipei Medical University.
- 2013-2013 Professor, School of Pharmacy, Taipei Medical University.
- 2006-2007 Professor, Graduate Institute of Pharmacognosy, Taipei Medical University.
- 2002-2006 Associate Professor, Graduate Institute of Pharmacognosy, Taipei Medical University.
Awards
- Editorial Board:
- International Journal of Advanced Chemistry (IJAC)
- International Journal of Organic Chemistry
- Der Pharma Chemica
- Journal of Chemical Science and Technology
- Advances in Organic Chemistry (AOC)
- Journal of Bone Marrow and Stem Cell Research
- Journal of Natural Products Research Updates
- Innovational: Journal of Chemistry (IJChem)
- International Journal of Biological Instrumentation
- Asian Council of Science
- Editorial Advisory Board:
- The Open Cancer Journal (ISSN: 1874-0790)
- Recent Patent Reviews on Anti-cancer Drug Discovery
- Outstanding reviewer:
- Outstanding reviewer: Bioorganic & Medicinal Chemistry
- Outstanding reviewer: European Journal of Medicinal Chemistry
Research Interests
- New drugs discovery and development
- Medicinal chemistry
- Discovery of novel anticancer drugs
- Discovery of novel anti-inflammatory drugs
URL
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Projects
治療膠質母細胞瘤之新穎小分子多標靶抗癌藥物之設計合成與開發
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
New Development Strategy for Novel Multitarget Anticancer Drug Discovery through Artificial Intelligence (Ai) and Machine Learning (Ml) Model
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies(2/2)
8/1/18 → 7/31/19
Project: A - Government Institution › b - Ministry of Science and Technology
Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies( I )( I )
8/1/17 → 7/31/18
Project: A - Government Institution › b - Ministry of Science and Technology
Development of Novel Tetracyclic and Heterocyclic Dual Topoisomerases Inhibitors as Anticancer Agents( II )
8/1/16 → 7/31/17
Project: A - Government Institution › b - Ministry of Science and Technology
Research Output
A novel salicylanilide derivative induces autophagy cell death in castration-resistant prostate cancer via ER stress-activated PERK signaling pathway
Hsieh, C-L., Huang, H-S., Chen, K-C., Saka, T., Chiang, C-Y., Chung, L. W. K. & Sung, S-Y., Jan 1 2020, In : Molecular Cancer Therapeutics. 19, 1, p. 101-111 11 p.Research output: Contribution to journal › Article
2
Citations
(Scopus)
CC12 induces apoptotic cell death and cell cycle arrest in human glioblastoma cell lines and mouse xenograft model
Fann, L. Y., Shih, J. H., Tseng, J. H., Huang, H. S. & Hsiao, S. H., Apr 2020, In : Molecules. 25, 8, 25081793.Research output: Contribution to journal › Article
Open Access
Preclinical evaluation of the novel small-molecule msi-n1014 for treating drug-resistant colon cancer via the lgr5/β-catenin/mir-142-3p network and reducing cancer-associated fibroblast transformation
Yadav, V. K., Huang, Y. J., George, T. A., Wei, P. L., Sumitra, M. R., Ho, C. L., Chang, T. H., Wu, A. T. H. & Huang, H. S., Jun 2020, In : Cancers. 12, 6, p. 1-15 15 p., 1590.Research output: Contribution to journal › Article
Open Access
TDAG8 deficiency reduces satellite glial number and pro-inflammatory macrophage number to relieve rheumatoid arthritis disease severity and chronic pain
Dai, S. P., Hsieh, W. S., Chen, C. H., Lu, Y. H., Huang, H. S., Chang, D. M., Huang, S. L. & Sun, W. H., May 29 2020, In : Journal of Neuroinflammation. 17, 1, 170.Research output: Contribution to journal › Article
Open Access
Temporal expression patterns of distinct cytokines and M1/M2 macrophage polarization regulate rheumatoid arthritis progression
Kung, C. C., Dai, S. P., Chiang, H., Huang, H. S. & Sun, W. H., Jan 1 2020, (Accepted/In press) In : Molecular Biology Reports.Research output: Contribution to journal › Article