Projects per year
Personal profile
Education
- 1996 Dr.rer.nat., Institute of Pharmacy, University of Regensburg, Germany
- 1987 Master, Institute of Pharmacy, National Defense Medical Center
- 1985 Bachelor, School of Pharmacy, National Defense Medical Center
Experience
- 2019- Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2018- Professor, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2018- Professor, Graduate Institute of Nanomedicine and Medical Engineering, Taipei Medical University
- 2016-2017 Professor,Ph.D. Program in Biotechnology Research and Development, Taipei Medical University.
- 2014-2018 Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University.
- 2013-2014 Professor, Department of Pharmaceutical Sciences, Taipei Medical University.
- 2013-2013 Professor, School of Pharmacy, Taipei Medical University.
- 2006-2007 Professor, Graduate Institute of Pharmacognosy, Taipei Medical University.
- 2002-2006 Associate Professor, Graduate Institute of Pharmacognosy, Taipei Medical University.
Awards
- Editorial Board:
- International Journal of Advanced Chemistry (IJAC)
- International Journal of Organic Chemistry
- Der Pharma Chemica
- Journal of Chemical Science and Technology
- Advances in Organic Chemistry (AOC)
- Journal of Bone Marrow and Stem Cell Research
- Journal of Natural Products Research Updates
- Innovational: Journal of Chemistry (IJChem)
- International Journal of Biological Instrumentation
- Asian Council of Science
- Editorial Advisory Board:
- The Open Cancer Journal (ISSN: 1874-0790)
- Recent Patent Reviews on Anti-cancer Drug Discovery
- Outstanding reviewer:
- Outstanding reviewer: Bioorganic & Medicinal Chemistry
- Outstanding reviewer: European Journal of Medicinal Chemistry
Research Interests
- New drugs discovery and development
- Medicinal chemistry
- Discovery of novel anticancer drugs
- Discovery of novel anti-inflammatory drugs
URL
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Projects
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治療膠質母細胞瘤之新穎小分子多標靶抗癌藥物之設計合成與開發
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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New Development Strategy for Novel Multitarget Anticancer Drug Discovery through Artificial Intelligence (Ai) and Machine Learning (Ml) Model
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
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Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies(2/2)
8/1/18 → 7/31/19
Project: A - Government Institution › b - Ministry of Science and Technology
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Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies( I )( I )
8/1/17 → 7/31/18
Project: A - Government Institution › b - Ministry of Science and Technology
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Development of Novel Tetracyclic and Heterocyclic Dual Topoisomerases Inhibitors as Anticancer Agents( II )
8/1/16 → 7/31/17
Project: A - Government Institution › b - Ministry of Science and Technology
Research output
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An integrated bioinformatics study of a novel niclosamide derivative, nsc765689, a potential gsk3β/β-catenin /stat3/ cd44 suppressor with anti-glioblastoma properties
Mokgautsi, N., Wen, Y. T., Lawal, B., Khedkar, H., Sumitra, M. R., Wu, A. T. H. & Huang, H. S., Mar 1 2021, In: International journal of molecular sciences. 22, 5, p. 1-23 23 p., 2464.Research output: Contribution to journal › Article › peer-review
Open Access -
LCC18, a benzamide-linked small molecule, ameliorates IgA nephropathy in mice
Yang, S. R., Hua, K. F., Takahata, A., Wu, C. Y., Hsieh, C. Y., Chiu, H. W., Chen, C. H., Mukhopadhyay, D., Suzuki, Y., Ka, S. M., Huang, H. S. & Chen, A., Apr 2021, In: Journal of Pathology. 253, 4, p. 427-441 15 p.Research output: Contribution to journal › Article › peer-review
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mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 Are Druggable Candidates for N-(2,4-Difluorophenyl)-2′,4′-Difluoro-4-Hydroxybiphenyl-3-Carboxamide (NSC765598), With Consequent Anticancer Implications
Lawal, B., Lee, C-Y., Mokgautsi, N., Sumitra, M. R., Khedkar, H., Wu, A. T. H. & Huang, H-S., Mar 2021, In: Frontiers in Oncology. 11Research output: Contribution to journal › Article › peer-review
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Pharmacoinformatics and preclinical studies of nsc765690 and nsc765599, potential stat3/cdk2/4/6 inhibitors with antitumor activities against nci60 human tumor cell lines
Lawal, B., Liu, Y. L., Mokgautsi, N., Khedkar, H., Sumitra, M. R., Wu, A. T. H. & Huang, H. S., 2021, In: Biomedicines. 9, 1, p. 1-22 22 p., 92.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Structure-based strategies for synthesis, lead optimization and biological evaluation of N-substituted anthra[1,2-c][1,2,5]thiadiazole-6,11-dione derivatives as potential multi-target anticancer agents
Ali, A. A. A., Lee, Y. R., Wu, A. T. H., Yadav, V. K., Yu, D. S. & Huang, H. S., Feb 2021, In: Arabian Journal of Chemistry. 14, 2, 102884.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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CCDC 1417633: Experimental Crystal Structure Determination
Lee, C. (Contributor), Liu, F. (Contributor), Chen, C. (Contributor), Chen, T. (Contributor), Liu, F. (Contributor), Ali, A. A. A. (Contributor), Chang, D. (Contributor) & Huang, H. (Contributor), Unknown Publisher, Jul 23 2015
DOI: 10.5517/cc1jl53d, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc1jl53d&sid=DataCite
Dataset