Projects per year
Personal profile
Education
- 1996 Dr.rer.nat., Institute of Pharmacy, University of Regensburg, Germany
- 1987 Master, Institute of Pharmacy, National Defense Medical Center
- 1985 Bachelor, School of Pharmacy, National Defense Medical Center
Experience
- 2019- Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2018- Professor, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2018- Professor, Graduate Institute of Nanomedicine and Medical Engineering, Taipei Medical University
- 2016-2017 Professor,Ph.D. Program in Biotechnology Research and Development, Taipei Medical University.
- 2014-2018 Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University.
- 2013-2014 Professor, Department of Pharmaceutical Sciences, Taipei Medical University.
- 2013-2013 Professor, School of Pharmacy, Taipei Medical University.
- 2006-2007 Professor, Graduate Institute of Pharmacognosy, Taipei Medical University.
- 2002-2006 Associate Professor, Graduate Institute of Pharmacognosy, Taipei Medical University.
Awards
- Editorial Board:
- International Journal of Advanced Chemistry (IJAC)
- International Journal of Organic Chemistry
- Der Pharma Chemica
- Journal of Chemical Science and Technology
- Advances in Organic Chemistry (AOC)
- Journal of Bone Marrow and Stem Cell Research
- Journal of Natural Products Research Updates
- Innovational: Journal of Chemistry (IJChem)
- International Journal of Biological Instrumentation
- Asian Council of Science
- Editorial Advisory Board:
- The Open Cancer Journal (ISSN: 1874-0790)
- Recent Patent Reviews on Anti-cancer Drug Discovery
- Outstanding reviewer:
- Outstanding reviewer: Bioorganic & Medicinal Chemistry
- Outstanding reviewer: European Journal of Medicinal Chemistry
Research Interests
- New drugs discovery and development
- Medicinal chemistry
- Discovery of novel anticancer drugs
- Discovery of novel anti-inflammatory drugs
Related Link
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Projects
- 9 Finished
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標靶整合素αvβ3-FAK訊號網絡的膽管癌診療策略開發-以PRS技術平台優化膽管癌的組合療法(1/3)
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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治療膠質母細胞瘤之新穎小分子多標靶抗癌藥物之設計合成與開發
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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New Development Strategy for Novel Multitarget Anticancer Drug Discovery through Artificial Intelligence (Ai) and Machine Learning (Ml) Model
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
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Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies(2/2)
8/1/18 → 7/31/19
Project: A - Government Institution › b - Ministry of Science and Technology
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Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies( I )( I )
8/1/17 → 7/31/18
Project: A - Government Institution › b - Ministry of Science and Technology
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Anticancer Activities of 9-chloro-6-(piperazin-1-yl)-11H-indeno[1,2-c] quinolin-11-one (SJ10) in Glioblastoma Multiforme (GBM) Chemoradioresistant Cell Cycle-Related Oncogenic Signatures
Mokgautsi, N., Kuo, Y. C., Tang, S. L., Liu, F. C., Chen, S. J., Wu, A. T. H. & Huang, H. S., Jan 1 2022, In: Cancers. 14, 1, 262.Research output: Contribution to journal › Article › peer-review
Open Access -
Liposome-encapsulated anthraquinone improves efficacy and safety in triple negative breast cancer
George, T. A., Chen, M. M., Czosseck, A., Chen, H. P., Huang, H. S. & Lundy, D. J., Feb 2022, In: Journal of Controlled Release. 342, p. 31-43 13 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
An integrated bioinformatics study of a novel niclosamide derivative, nsc765689, a potential gsk3β/β-catenin /stat3/ cd44 suppressor with anti-glioblastoma properties
Mokgautsi, N., Wen, Y. T., Lawal, B., Khedkar, H., Sumitra, M. R., Wu, A. T. H. & Huang, H. S., Mar 1 2021, In: International journal of molecular sciences. 22, 5, p. 1-23 23 p., 2464.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
A preclinical investigation of gbm-n019 as a potential inhibitor of glioblastoma via exosomal mtor/cdk6/stat3 signaling
Wu, A. T. H., Huang, H. S., Wen, Y. T., Lawal, B., Mokgautsi, N., Huynh, T. T., Hsiao, M. & Wei, L., Sep 11 2021, In: Cells. 10, 9, 2391.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
A preclinical report of a cobimetinib-inspired novel anticancer small-molecule scaffold of isoflavones, NSC777213, for targeting PI3K/AKT/mTOR/MEK in multiple cancers
Lawal, B., Lo, W-C., Mokgautsi, N., Sumitra, M. R., Khedkar, H., Wu, A. T. & Huang, H-S., 2021, In: American Journal of Cancer Research. 11, 6, p. 2590-2617 28 p.Research output: Contribution to journal › Article › peer-review
Datasets
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CCDC 1417633: Experimental Crystal Structure Determination
Lee, C. (Contributor), Liu, F. (Contributor), Chen, C. (Contributor), Chen, T. (Contributor), Liu, F. (Contributor), Ali, A. A. A. (Contributor), Chang, D. (Contributor) & Huang, H. (Contributor), Unknown Publisher, Jul 23 2015
DOI: 10.5517/cc1jl53d, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc1jl53d&sid=DataCite
Dataset