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Research Output 1989 2019

2019

Differences between COPD patients and their families regarding willingness toward life-sustaining treatments

Chen, T. R., Hu, W. Y., Chiu, T. Y. & Kuo, H. P., Jan 2019, (Accepted/In press) In : Journal of the Formosan Medical Association. 118, 1P3, p. 414-419

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Therapeutics
Medical Futility
Persistent Vegetative State
Noninvasive Ventilation
1 Citation (Scopus)
Health Education
Non-Small Cell Lung Carcinoma
Randomized Controlled Trials
Quality of Life
Drug Therapy
2 Citations (Scopus)

Endotypes of severe allergic asthma patients who clinically benefit from anti-IgE therapy

Huang, Y. C., Weng, C. M., Lee, M. J., Lin, S. M., Wang, C. H. & Kuo, H-P., Jan 1 2019, In : Clinical and Experimental Allergy. 49, 1, p. 44-53 10 p.

Research output: Contribution to journalArticle

Asthma
Therapeutics
Cytokines
Inflammation
anti-IgE antibodies
2018
8 Citations (Scopus)

Aryl hydrocarbon receptor activation by diesel exhaust particles mediates epithelium-derived cytokines expression in severe allergic asthma

Weng, C. M., Wang, C. H., Lee, M. J., He, J. R., Huang, H. Y., Chao, M. W., Chung, K. F. & Kuo, H-P., Nov 1 2018, In : Allergy: European Journal of Allergy and Clinical Immunology. 73, 11, p. 2192-2204 13 p.

Research output: Contribution to journalArticle

Vehicle Emissions
Aryl Hydrocarbon Receptors
Interleukin-17
Asthma
Epithelium
3 Citations (Scopus)

Diesel exhaust particles up-regulate interleukin-17A expression via ROS/NF-κB in airway epithelium

Weng, C. M., Lee, M. J., He, J. R., Chao, M. W., Wang, C. H. & Kuo, H. P., May 1 2018, In : Biochemical Pharmacology. 151, p. 1-8 8 p.

Research output: Contribution to journalArticle

Vehicle Emissions
Interleukin-17
Up-Regulation
Epithelium
Asthma

Identification of chronic obstructive pulmonary disease subgroups in 13 Asian cities

Kim, W. J., Gupta, V., Nishimura, M., Makita, H., Idolor, L., Roa, C., Loh, L. C., Ong, C. K., Wang, J. S., Boonsawat, W., Gunasekera, K. D., Madegedara, D., Kuo, H. P., Wang, C. H., Wang, C., Yang, T., Lin, Y. X., Ko, F. W. S., Hui, D. S. C., Lan, L. T. T. & 8 others, Vu, Q. T. T., Bhome, A. B., Ng, A., Seo, J. B., Lee, B. Y., Lee, J. S., Oh, Y. M. & Lee, S. D., Jul 1 2018, In : International Journal of Tuberculosis and Lung Disease. 22, 7, p. 820-826 7 p.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Statistical Factor Analysis
Cluster Analysis
Phenotype
Forced Expiratory Volume
2 Citations (Scopus)

Increased matrix metalloproteinase-9 to tissue inhibitor of metalloproteinase-1 ratio in smokers with airway hyperresponsiveness and accelerated lung function decline

Lo, C. Y., Huang, H-Y., He, J-R., Huang, T-T., Heh, C-C., Sheng, T-F., Chung, K. F., Kuo, H-P. & Wang, C. H., Apr 11 2018, In : International Journal of COPD. 13, p. 1135-1144 10 p.

Research output: Contribution to journalArticle

Open Access
Tissue Inhibitor of Metalloproteinase-1
Matrix Metalloproteinase 9
Alveolar Macrophages
Lung
Forced Expiratory Volume
2017
1 Citation (Scopus)

Capnography monitoring the hypoventilation during the induction of bronchoscopic sedation: A randomized controlled trial

Lin, T. Y., Fang, Y. F., Huang, S. H., Wang, T. Y., Kuo, C. H., Wu, H. T., Kuo, H. P. & Lo, Y. L., Dec 1 2017, In : Scientific Reports. 7, 1, 8685.

Research output: Contribution to journalArticle

Capnography
Hypoventilation
Randomized Controlled Trials
Bronchoscopy
Control Groups
2 Citations (Scopus)

Different perceptions of narrative medicine between Western and Chinese medicine students

Huang, C. D., Liao, K. C., Chung, F. T., Tseng, H. M., Fang, J. T., Lii, S. C., Kuo, H. P., Yeh, S. J. & Lee, S. T., May 10 2017, In : BMC Medical Education. 17, 1, 85.

Research output: Contribution to journalArticle

medicine
narrative
student
learning culture
questionnaire
6 Citations (Scopus)

Early management of sepsis with emphasis on early goal directed therapy: AME evidence series 002

Zhang, Z., Hong, Y., Smischney, N. J., Kuo, H. P., Tsirigotis, P., Rello, J., Kuan, W. S., Jung, C., Robba, C., Taccone, F. S., Leone, M., Spapen, H., Grimaldi, D., Poucke, S. V., Simpson, S. Q., Honore, P. M., Hofer, S. & Caironi, P., Jan 1 2017, In : Journal of Thoracic Disease. 9, 2, p. 392-405 14 p.

Research output: Contribution to journalArticle

Sepsis
Therapeutics
Intensive Care Units
Hospital Emergency Service
methylamphotericin B
8 Citations (Scopus)

Heat shock protein70 is implicated in modulating NF-κ B activation in alveolar macrophages of patients with active pulmonary tuberculosis

Wang, C. H., Chou, P. C., Chung, F. T., Lin, H. C., Huang, K. H. & Kuo, H. P., Dec 1 2017, In : Scientific Reports. 7, 1, 1214.

Research output: Contribution to journalArticle

Alveolar Macrophages
Pulmonary Tuberculosis
Shock
Tuberculosis
Hot Temperature
8 Citations (Scopus)

Impact of chronic rhinosinusitis on severe asthma patients

Lee, T. J., Fu, C. H., Wang, C. H., Huang, C. C., Huang, C. C., Chang, P. H., Chen, Y. W., Wu, C. C., Wu, C. L. & Kuo, H. P., Feb 1 2017, In : PLoS One. 12, 2, e0171047.

Research output: Contribution to journalArticle

asthma
Asthma
Interleukin-17
Cytokines
interleukins
8 Citations (Scopus)

Obstructive sleep apnoea accelerates FEV1 decline in asthmatic patients

Wang, T. Y., Lo, Y. L., Lin, S. M., Huang, C. D., Chung, F. T., Lin, H. C., Wang, C. H. & Kuo, H. P., Mar 21 2017, In : BMC Pulmonary Medicine. 17, 1, 55.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Apnea
Asthma
Continuous Positive Airway Pressure
Lung
17 Citations (Scopus)

Oncostatin M-preconditioned mesenchymal stem cells alleviate bleomycin-induced pulmonary fibrosis through paracrine effects of the hepatocyte growth factor

Lan, Y. W., Theng, S. M., Huang, T. T., Choo, K. B., Chen, C. M., Kuo, H. P. & Chong, K. Y., Mar 1 2017, In : Stem cells translational medicine. 6, 3, p. 1006-1017 12 p.

Research output: Contribution to journalArticle

Oncostatin M
Hepatocyte Growth Factor
Pulmonary Fibrosis
Bleomycin
Mesenchymal Stromal Cells

Reduced suppressive effect of β2-adrenoceptor agonist on fibrocyte function in severe asthma

Lo, C. Y., Michaeloudes, C., Bhavsar, P. K., Huang, C. D., Chang, P. J., Wang, C. H., Kuo, H. P. & Chung, K. F., Nov 21 2017, In : Respiratory Research. 18, 1, 194.

Research output: Contribution to journalArticle

Adrenergic Receptors
Asthma
Cyclic AMP
Adrenergic Agonists
Adrenal Cortex Hormones
2016
8 Citations (Scopus)
Taiwan
Cohort Studies
Asthma
Steroids
Databases
2 Citations (Scopus)

Exercise-Induced Changes in Exhaled NO Differentiates Asthma with or Without Fixed Airway Obstruction from COPD with Dynamic Hyperinflation

Huang, S. Y., Chou, P. C., Wang, T. Y., Lo, Y. L., Joa, W. C., Chen, L. F., Sheng, T. F., Chung, K. F., Wang, C. H. & Kuo, H. P., Apr 1 2016, In : Medicine (United States). 95, 15, e3400.

Research output: Contribution to journalArticle

Airway Obstruction
Chronic Obstructive Pulmonary Disease
Asthma
Exercise
Nitric Oxide
6 Citations (Scopus)
Chronic Obstructive Pulmonary Disease
Body Mass Index
Mortality
Confidence Intervals
Geriatric Assessment
3 Citations (Scopus)

Pulmonary rehabilitation coupled with negative pressure ventilation decreases decline in lung function, hospitalizations, and medical cost in COPD: A 5-year study

Huang, H. Y., Chou, P. C., Joa, W. C., Chen, L. F., Sheng, T. F., Lin, H. C., Yang, L. Y., Pan, Y. B., Chung, F. T., Wang, C. H. & Kuo, H. P., Oct 1 2016, In : Medicine. 95, 41, p. e5119

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Ventilation
Hospitalization
Rehabilitation
Pressure
2 Citations (Scopus)

The safety and efficacy of alfentanil-based induction in bronchoscopy sedation: A randomized, double-blind, controlled trial

Hsieh, C. H., Lin, T. Y., Wang, T. Y., Kuo, C. H., Lin, S. M., Kuo, H. P. & Lo, Y. L., Jan 1 2016, In : Medicine (United States). 95, 43, e5101.

Research output: Contribution to journalArticle

Alfentanil
Bronchoscopy
Propofol
Safety
Cough
2015
17 Citations (Scopus)

A biologically inspired lung-on-a-chip device for the study of protein-induced lung inflammation

Punde, T. H., Wu, W. H., Lien, P. C., Chang, Y. L., Kuo, P. H., Chang, M. D. T., Lee, K. Y., Huang, C. D., Kuo, H. P., Chan, Y. F., Shih, P. C. & Liu, C. H., Feb 1 2015, In : Integrative Biology (United Kingdom). 7, 2, p. 162-169 8 p.

Research output: Contribution to journalArticle

Eosinophil Cationic Protein
Blood vessels
Blood Vessels
Pneumonia
Microfluidics
7 Citations (Scopus)

Areal-world evaluation of indacaterol and other bronchodilators in COPD: The INFLOW study

Juvelekian, G., El-Sorougi, W., Pothirat, C., Yunus, F., De Guia, T., Kuo, H. P., Patnaik, S. B. & Pilipovic, V., Oct 5 2015, In : International Journal of COPD. 10, 1, p. 2109-2120 12 p.

Research output: Contribution to journalArticle

Bronchodilator Agents
Chronic Obstructive Pulmonary Disease
Physicians
Eastern Africa
Middle East
11 Citations (Scopus)

Associated bone mineral density and obstructive sleep apnea in chronic obstructive pulmonary disease

Wang, T. Y., Lo, Y. L., Chou, P. C., Chung, F. T., Lin, S. M., Lin, T. Y., Lin, H. C., Wang, C. H., Yu, C. T. & Kuo, H. P., Jan 29 2015, In : International Journal of COPD. 10, p. 231-237 7 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Bone Density
Chronic Obstructive Pulmonary Disease
Total Lung Capacity
Polysomnography

Association of body-mass index to circumference of body and limbs, inspiratory capacity, and inflammatory biomarker in emphysematous patients

Chung, F. T., Joa, W. C., Chen, L. F., Chen, H. C., Sheng, T. F., Kuo, H. P. & Wang, C. H., Oct 1 2015, In : Journal of Internal Medicine of Taiwan. 26, 5, p. 277-284 8 p.

Research output: Contribution to journalArticle

Inspiratory Capacity
Body Mass Index
Extremities
Biomarkers
Emphysema
18 Citations (Scopus)

Bispectral index in evaluating effects of sedation depth on drug-induced sleep endoscopy

Lo, Y. L., Ni, Y. L., Wang, T. Y., Lin, T. Y., Li, H. Y., White, D. P., Lin, J. R. & Kuo, H. P., Jan 1 2015, In : Journal of Clinical Sleep Medicine. 11, 9, p. 1011-1020 10 p.

Research output: Contribution to journalArticle

Prolapse
Oropharynx
Endoscopy
Obstructive Sleep Apnea
Sleep
1 Citation (Scopus)

Bronchoscopic debulking for endobronchial malignancy: Predictors of recanalization and recurrence

Kuo, S. C. H., Lo, Y. L., Chou, C. L., Chung, F. T., Lin, S. M., Liu, C. Y. & Kuo, H. P., Jan 1 2015, In : Thoracic Cancer. 6, 6, p. 722-730 9 p.

Research output: Contribution to journalArticle

Recurrence
Neoplasms
Cryotherapy
Palliative Care
Odds Ratio
9 Citations (Scopus)

Circulating Angiopopietin-1 Correlates with the Clinical Course of Multiple Organ Dysfunction Syndrome and Mortality in Patients with Severe Sepsis

Lin, S. M., Chung, F. T., Kuo, C. H., Chou, P. C., Wang, T. Y., Chang, P. J., Lo, Y. L., Huang, C. D., Lin, H. C., Wang, C. H., Kuo, H. P. & Eriksson., E., Jan 1 2015, In : Medicine (United States). 94, 20, e878.

Research output: Contribution to journalArticle

Angiopoietin-1
Multiple Organ Failure
Sepsis
Angiopoietin-2
Mortality
20 Citations (Scopus)

Fibrocyte trafficking in patients with chronic obstructive asthma and during an acute asthma exacerbation

Wang, C. H., Punde, T. H., Huang, C. D., Chou, P. C., Huang, T. T., Wu, W. H., Liu, C. H., Chung, K. F. & Kuo, H. P., May 1 2015, In : Journal of Allergy and Clinical Immunology. 135, 5, p. 1154-1162e5

Research output: Contribution to journalArticle

Asthma
Chemokine CCL19
Chemokine CXCL12
Chemokine Receptors
Chemotactic Factors
7 Citations (Scopus)

Flexible bronchoscopy with multiple modalities for foreign body removal in adults

Fang, Y-F., Hsieh, M-H., Chung, F-T., Huang, Y-K., Chen, G-Y., Lin, S-M., Lin, H-C., Wang, C-H. & Kuo, H-P., 2015, In : PLoS One. 10, 3, p. e0118993

Research output: Contribution to journalArticle

bronchoscopy
foreign bodies
Bronchoscopy
Foreign Bodies
Cryotherapy
62 Citations (Scopus)

Hypoxia-preconditioned mesenchymal stem cells attenuate bleomycin-induced pulmonary fibrosis

Lan, Y. W., Choo, K. B., Chen, C. M., Hung, T. H., Chen, Y. B., Hsieh, C. H., Kuo, H. P. & Chong, K. Y., May 20 2015, In : Stem Cell Research and Therapy. 6, 1, 97.

Research output: Contribution to journalArticle

Pulmonary Fibrosis
Bleomycin
Stem cells
Mesenchymal Stromal Cells
Lung
23 Citations (Scopus)

Increased phenotypic differentiation and reduced corticosteroid sensitivity of fibrocytes in severe asthma

Lo, C. Y., Michaeloudes, C., Bhavsar, P. K., Huang, C. D., Wang, C. H., Kuo, H. P. & Chung, K. F., May 1 2015, In : Journal of Allergy and Clinical Immunology. 135, 5, p. 1186-1195e6

Research output: Contribution to journalArticle

Adrenal Cortex Hormones
Asthma
CC Chemokines
Chemokine Receptors
Airway Remodeling
11 Citations (Scopus)

Low bone mineral density in COPD patients with osteoporosis is related to low daily physical activity and high COPD assessment test scores

Liu, W. T., Kuo, H. P., Liao, T. H., Chiang, L. L., Chen, L. F., Hsu, M. F., Chuang, H. C., Lee, K. Y., Huang, C. D. & Ho, S. C., Sep 1 2015, In : International Journal of COPD. 10, 1, p. 1737-1744 8 p.

Research output: Contribution to journalArticle

Bone Density
Chronic Obstructive Pulmonary Disease
Osteoporosis
Exercise
Femur Neck

The Impact of Sequence of Chemotherapy and EGFR-TKI Treatment on Different EGFR Mutation Lung Adenocarcinoma

Chung, F. T., Ho, M. Y., Fang, Y. F., Hshieh, M. H., Wang, T. Y., Kuo, C. H., Chen, H. C., Wang, C. H., Lin, S. M., Yu, C. T., Lin, H. C. & Kuo, H. P., Jan 1 2015, In : BioMed Research International. 2015, 948267.

Research output: Contribution to journalArticle

Chemotherapy
Epidermal Growth Factor Receptor
Drug Therapy
Mutation
Therapeutics
6 Citations (Scopus)

The relationship between anthropometric indicators and walking distance in patients with chronic obstructive pulmonary disease

Ho, S. C., Hsu, M. F., Kuo, H. P., Wang, J. Y., Chen, L. F., Lee, K. Y. & Chuang, H. C., 2015, In : International Journal of COPD. 10, 1, p. 1857-1862 6 p.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Walking
Exercise
Body Mass Index
Logistic Models
4 Citations (Scopus)

Vocal cord dysfunction diagnosed by four-dimensional dynamic volume computed tomography in patients with difficult-to-treat asthma: A case series

Cheng, W. T., Chen, H. W., Su, I. H., Fang, J. T., Kuo, H. P. & Huang, C. D., Dec 1 2015, In : Journal of the Formosan Medical Association. 114, 12, p. 1285-1290 6 p.

Research output: Contribution to journalArticle

Vocal Cord Dysfunction
Cone-Beam Computed Tomography
Asthma
Laryngoscopy
Early Diagnosis
2014
23 Citations (Scopus)
Sirolimus
Respiratory Insufficiency
Pneumonia
Steroids
Mechanical Ventilators
Air Pollution
Chronic Obstructive Pulmonary Disease
Osteoporosis
Adrenal Cortex Hormones
Taiwan
9 Citations (Scopus)
Needles
Tuberculosis
Sarcoidosis
Anthracosis
Bronchoscopy
2 Citations (Scopus)

A rare case of the coexistence of latent tuberculosis and necrotizing sarcoid granulomatosis with atypical presentation

Hsiung, T. C., Kuo, C. H. & Kuo, H. P., Jan 1 2014, In : Journal of the Formosan Medical Association. 113, 9, p. 662-663 2 p.

Research output: Contribution to journalLetter

Pulmonary Sarcoidosis
Latent Tuberculosis
X Ray Computed Tomography
Differential Diagnosis
Lymph Nodes
16 Citations (Scopus)

Clinical characteristics and treatment outcomes of patients with low- and high-concentration isoniazid-monoresistant tuberculosis

Wang, T. Y., Lin, S. M., Shie, S. S., Chou, P. C., Huang, C. D., Chung, F. T., Kuo, C. H., Chang, P. J. & Kuo, H. P., Jan 22 2014, In : PLoS One. 9, 1, e86316.

Research output: Contribution to journalArticle

isoniazid
Pyrazinamide
Isoniazid
Rifampin
tuberculosis
8 Citations (Scopus)

Comparison of the efficacy of ciclesonide with that of budesonide in mild to moderate asthma patients after step-down therapy: A randomised parallel-group study

Chiu, K. C., Chou, Y. L., Hsu, J. Y., Lin, M. S., Lin, C. H., Chou, P. C., Chou, C. L., Wang, C. H. & Kuo, H. P., May 20 2014, In : npj Primary Care Respiratory Medicine. 24, 14010.

Research output: Contribution to journalArticle

Budesonide
Asthma
Forced Expiratory Volume
Adrenal Cortex Hormones
Therapeutics
7 Citations (Scopus)

Endobronchial ultrasound-guided transbronchial biopsy and brushing: A comparative evaluation for the diagnosis of peripheral pulmonary lesions

Kuo, C. H., Lin, S. M., Lee, K. Y., Chung, F. T., Lo, Y. L., Hsiung, T. C., Liu, C. Y. & Kuo, H. P., 2014, In : European Journal of Cardio-thoracic Surgery. 45, 5, p. 894-898 5 p., ezt472.

Research output: Contribution to journalArticle

Biopsy
Lung
10 Citations (Scopus)
Nutrition Assessment
Nutritional Status
Chronic Obstructive Pulmonary Disease
Cross-Sectional Studies
Malnutrition
14 Citations (Scopus)

Mobile-phone-based home exercise training program decreases systemic inflammation in COPD: A pilot study

Wang, C. H., Chou, P. C., Joa, W. C., Chen, L. F., Sheng, T. F., Ho, S. C., Lin, H. C., Huang, C. D., Chung, F. T., Chung, K. F. & Kuo, H. P., 2014, In : BMC Pulmonary Medicine. 14, 1, 142.

Research output: Contribution to journalArticle

Cell Phones
Chronic Obstructive Pulmonary Disease
Exercise
Inflammation
Education
11 Citations (Scopus)
Interleukin-8
Mycobacterium tuberculosis
Monocytes
Down-Regulation
Bacterial Load
4 Citations (Scopus)

PPARγ ligand ciglitazone inhibits TNFα-induced ICAM-1 in human airway smooth muscle cells

Huang, C. D., Hsiung, T. C., Ho, S. C., Lee, K. Y., Chan, Y. F., Kuo, L. W., Lin, S. M., Wang, C. H., Lin, H. C. & Kuo, H. P., 2014, In : Biomedical Journal. 37, 4, p. 191-198 8 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Intercellular Adhesion Molecule-1
Smooth Muscle Myocytes
Tumor Necrosis Factor-alpha
Ligands
242 Citations (Scopus)
Chemoradiotherapy
Non-Small Cell Lung Carcinoma
Placebos
Survival
Random Allocation
2013
19 Citations (Scopus)

Characteristics of stable chronic obstructive pulmonary disease patients in the pulmonology clinics of seven Asian cities

Oh, Y. M., Bhome, A. B., Boonsawat, W., Gunasekera, K. D., Madegedara, D., Idolor, L., Roa, C., Kim, W. J., Kuo, H. P., Wang, C. H., Lan, L. T. T., Loh, L. C., Ong, C. K., Ng, A., Nishimura, M., Makita, H., Silverman, E. K., Lee, J. S., Yang, T., Lin, Y. & 2 others, Wang, C. & Lee, S. D., Jan 11 2013, In : International Journal of COPD. 8, p. 31-39 9 p.

Research output: Contribution to journalArticle

Pulmonary Medicine
Chronic Obstructive Pulmonary Disease
Biomass
Quality of Life
Bronchodilator Agents
9 Citations (Scopus)

Chronic cough and obstructive sleep apnoea in a sleep laboratory-based pulmonary practice

Wang, T. Y., Lo, Y. L., Liu, W. T., Lin, S. M., Lin, T. Y., Kuo, C. H., Chung, F. T., Chou, P. C., Chang, P. J., Ni, Y. L., Ho, S. C., Lin, H. C., Wang, C. H., Yu, C. T. & Kuo, H. P., Nov 5 2013, In : Cough. 9, 1, 24.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Cough
Sleep
Lung
Continuous Positive Airway Pressure
11 Citations (Scopus)
curriculum evaluation
medicine
resident
evaluation
knowledge