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Research Output

  • 2644 Citations
  • 27 h-Index
  • 61 Article
  • 3 Chapter
  • 2 Comment/debate
4 Citations (Scopus)
6 Citations (Scopus)

Adrenal crisis due to metastatic carcinoma of the adrenal glands.

Wang, J. M. & Lai, G. M., Sep 20 1987, Changgeng yi xue za zhi / Changgeng ji nian yi yuan = Chang Gung medical journal / Chang Gung Memorial Hospital. 3 ed. Vol. 10. p. 245-250 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

22 Citations (Scopus)

Aspirin antagonizes the cytotoxic effect of methotrexate in lung cancer cells

Yan, K. H., Lee, L. M., Hsieh, M-C., Yan, M. D., Yao, C. J., Chang, P. Y., Chen, T. L., Chang, H. Y., Cheng, A. L., Lai, G. M. & Chuang, S. E., Sep 2013, In : Oncology Reports. 30, 3, p. 1497-1505 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Basal levels and patterns of anticancer drug-induced activation of nuclear factor-κB (NF-κB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells

Chuang, S. E., Yeh, P. Y., Lu, Y. S., Lai, G. M., Liao, C. M., Gao, M. & Cheng, A. L., May 1 2002, In : Biochemical Pharmacology. 63, 9, p. 1709-1716 8 p.

Research output: Contribution to journalArticle

138 Citations (Scopus)

Bone marrow metastases from solid tumors--clinical analysis of 96 cases.

Wang, J. M., Shih, L. Y., Lai, G. M. & Ng, K. T., Dec 20 1987, Changgeng yi xue za zhi / Changgeng ji nian yi yuan = Chang Gung medical journal / Chang Gung Memorial Hospital. 4 ed. Vol. 10. p. 283-293 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Carbonic anhydrase III promotes transformation and invasion capability in hepatoma cells through FAK signaling pathway

Dai, H. Y., Hong, C. C., Liang, S. C., Yan, M. D., Lai, G. M., Cheng, A. L. & Chuang, S. E., Dec 2008, In : Molecular Carcinogenesis. 47, 12, p. 956-963 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
3 Citations (Scopus)

Cisplatin and 5-fluorouracil as neoadjuvant chemotherapy: Predicting response in head and neck squamous cell cancer

Wang, H. M., Wang, C. H., Chen, J. S., Chang, H. K., Kiu, M. C., Liaw, C. C., Ng, K. T. & Lai, G. M., 1995, In : Journal of the Formosan Medical Association = Taiwan yi zhi. 94, 3, p. 87-94 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Clinical trial of low-dose rHuG-CSF in neutropenic cancer patients following anti-cancer chemotherapy

Chang, M. C., Lai, G. M., Tsan, K. W., Wang, R. S. & Wu, J. H., Nov 1996, In : Journal of the Formosan Medical Association = Taiwan yi zhi. 95, 11, p. 845-850 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Combination chemotherapy with carmustine and cisplatin before, during, and after radiotherapy for adult malignant gliomas

Kiu, M. C., Chang, C. N., Cheng, W. C., Lin, T. K., Wong, C. W., Tang, S. G., Leung, W. M., Chen, L. H., Ho, Y. S., Ng, K. T., Chen, J. S., Yang, T. H. & Lai, G. M., Oct 1995, In : Journal of Neuro-Oncology. 25, 3, p. 215-220 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Contribution of glutathione and glutathione‐dependent enzymes in the reversal of adriamycin resistance in colon carcinoma cell lines

Lai, G. M., Moscow, J. A., Alvarez, M. G., Fojo, A. T. & Bates, S. E., 1991, In : International Journal of Cancer. 49, 5, p. 688-695 8 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
9 Citations (Scopus)

Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis

Chuang, S. E., Kuo, M. L., Hsu, C. H., Chen, C. R., Lin, J. K., Lai, G. M., Hsieh, C. Y. & Cheng, A. L., 2000, In : Carcinogenesis. 21, 2, p. 331-335 5 p.

Research output: Contribution to journalArticle

215 Citations (Scopus)

Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells

Yeh, C. T., Rao, Y. K., Yao, C. J., Yeh, C. F., Li, C. H., Chuang, S. E., Luong, J. H. T., Lai, G. M. & Tzeng, Y. M., Nov 18 2009, In : Cancer Letters. 285, 1, p. 73-79 7 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)
11 Citations (Scopus)

Dramatic synergistic anticancer effect of clinically achievable doses of lovastatin and troglitazone

Yao, C. J., Lai, G. M., Chan, C. F., Cheng, A. L., Yang, Y. Y. & Chuang, S. E., Mar 1 2006, In : International Journal of Cancer. 118, 3, p. 773-779 7 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Effect of glutathione on DNA repair in cisplatin-resistant human ovarian cancer cell lines

Lai, G. M., Ozols, R. F., Young, R. C. & Hamilton, T. C., Apr 5 1989, In : Journal of the National Cancer Institute. 81, 7, p. 535-539 5 p.

Research output: Contribution to journalArticle

155 Citations (Scopus)

Electrospun polylactic acid (PLLA) microtube array membrane (MTAM)-An advanced substrate for anticancer drug screening

Tseng, C. H., Huang, W. T., Chew, C. H., Lai, J. K., Tu, S. H., Wei, P. L., Lee, K. Y., Lai, G. M. & Chen, C. C., Feb 14 2019, In : Materials. 12, 4, 569.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Elimination of cancer stem-like cells and potentiation of temozolomide sensitivity by honokiol in glioblastoma multiforme cells

Lai, I. C., Shih, P. H., Yao, C-J., Yeh, C-T., Wang-Peng, J., Lui, T-N., Chuang, S. E., Hu, T. S., Lai, T-Y. & Lai, G-M., Mar 12 2015, In : PLoS One. 10, 3, e0114830.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Elimination of cancer stem-like side population cells in hepatoma cell lines by Chinese herbal mixture Tien-Hsien Liquid

Yao, C. J., Yeh, C-T., Lee, L. M., Chuang, S. E., Yeh, C. F., Chao, W. J., Lai, T-I. & Lai, G. M., 2012, In : Evidence-based Complementary and Alternative Medicine. 2012, 617085.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Elimination of cancer stem-like side population in human glioblastoma cells accompanied with stemness gene suppression by Korean herbal recipe MSC500

Yao, C. J., Han, T. Y., Shih, P. H., Yi, T. Y., Lai, I. C., Chang, K. H., Lai, T-I., Chang, C. L. & Lai, G. M., Nov 19 2014, In : Integrative Cancer Therapies. 13, 6, p. 541-554 14 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Enhanced DNA repair and resistance to cisplatin in human ovarian cancer

Lai, G. M., Ozols, R. F., Smyth, J. F., Young, R. C. & Hamilton, T. C., Dec 15 1988, In : Biochemical Pharmacology. 37, 24, p. 4597-4600 4 p.

Research output: Contribution to journalArticle

150 Citations (Scopus)

Epidemiological characteristics and multiple risk factors of stomach cancer in Taiwan

Lee, H. H., Wu, H. Y., Chuang, Y. C., Chang, A. S., Chao, H. H., Chen, K. Y., Chen, H. K., Lai, G. M., Huang, H. H. & Chen, C. J., 1990, In : Anticancer Research. 10, 4, p. 875-882 8 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Epidemiologic characteristics and multiple risk factors of lung cancer in Taiwan

Chen, C. J., Wu, H. Y., Chuang, Y. C., Chang, A. S., Luh, K. T., Chao, H. H., Chen, K. Y., Chen, S. G., Lai, G. M., Huang, H. H. & Lee, H. H., 1990, In : Anticancer Research. 10, 4, p. 971-976 6 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Erratum: Oxidative stress enhances AXL-mediated cell migration through AKT1/Rac1-dependent mechanism (Free Radical Biology and Medicine (2013) 65 (1246-1256))

Huang, J. S., Cho, C. Y., Hong, C. C., Yan, M. D., Hsieh, M-C., Lay, J. D., Lai, G. M., Ann-Lii, C. & Chuang, S. E., Feb 2014, In : Free Radical Biology and Medicine. 67, p. 416 1 p.

Research output: Contribution to journalArticle

Expression of epidermal growth factor receptor in head and neck cancers correlates with clinical progression: A multicentre immunohistochemical study in the Asia-Pacific region

Putti, T. C., To, K. F., Hsu, H. C., Chan, A. T. C., Lai, G. M., Tse, G., Lee, Y. S., Whang-Peng, J., Millward, M., Lin, L., Lin, X. & Lee, C. S., 2002, In : Histopathology. 41, 2, p. 144-151 8 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Fucoidan elevates MicroRNA-29b to regulate DNMT3B-MTSS1 axis and inhibit EMT in human hepatocellular carcinoma cells

Yan, M. D., Yao, C. J., Chow, J. M., Chang, C. L., Hwang, P. A., Chuang, S. E., Whang-Peng, J. & Lai, G. M., Oct 1 2015, In : Marine Drugs. 13, 10, p. 6099-6116 18 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
29 Citations (Scopus)

Honokiol-induced apoptosis and autophagy in glioblastoma multiforme cells

Chang, K. H., Yan, M. D., Yao, C. J., Lin, P. C. & Lai, G. M., Nov 2013, In : Oncology Letters. 6, 5, p. 1435-1438 4 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
19 Citations (Scopus)
71 Citations (Scopus)

Identification and characterization of a novel gene Saf transcribed from the opposite strand of Fas

Yan, M. D., Hong, C. C., Lai, G. M., Cheng, A. L., Lin, Y. W. & Chuang, S. E., Jun 1 2005, In : Human Molecular Genetics. 14, 11, p. 1465-1474 10 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform

Lin, H. S., Huang, Y. L., Wang, Y. R., Hsiao, E., Hsu, T. A., Shiao, H. Y., Jiaang, W. T., Sampurna, B. P., Lin, K. H., Wu, M. S., Lai, G. M. & Yuh, C. H., Jun 1 2019, In : Cancers. 11, 6, 739.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Increased DNA repair as a mechanism of acquired resistance to cis-diamminedichloroplatinum(II) in human ovarian cancer cell lines

Masuda, H., Ozols, R. F., Lai, G. M., Fojo, A., Rothenberg, M. & Hamilton, T. C., 1988, In : Cancer Research. 48, 20, p. 5713-5716 4 p.

Research output: Contribution to journalArticle

295 Citations (Scopus)
13 Citations (Scopus)

Intensive Chemotherapy plus Recombinant Human Granulocyte Colony Stimulating Factor Support for Distant Metastatic Nasopharyngeal Carcinoma

Wang, C. H., Wang, H. M., Chen, J. S., Chang, W. J. & Lai, G. M., Jan 1997, In : Oncology. 54, SUPPL. 1, p. 34-37 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells

Chen, C. N., Huang, H. H., Wu, C. L., Lin, C. P. C., Hsu, J. T. A., Hsieh, H. P., Chuang, S. E. & Lai, G. M., Feb 8 2007, In : Cancer Letters. 246, 1-2, p. 237-252 16 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Malignant germ cell tumors in adults and adolescents--analysis of 36 cases including testis, mediastinum and retroperitoneum origins

Liaw, C. C., Ng, K. T., Lai, G. M., Chen, M. H., Lin, F. J. & Huang, M. H., Sep 20 1986, Changgeng yi xue za zhi / Changgeng ji nian yi yuan = Chang Gung medical journal / Chang Gung Memorial Hospital. 3 ed. Vol. 9. p. 194-203 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Malignant thyroid teratoma of an adult: A long-term survival after chemotherapy

Chen, J. S., Lai, G. M. & Hsueh, S., Apr 1998, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 21, 2, p. 212-214 3 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Mechanisms of resistance to cisplatin and alkylating agents.

Hamilton, T. C., Lai, G. M., Rothenberg, M. L., Fojo, A. T., Young, R. C. & Ozols, R. F., 1989, In : Cancer Treatment and Research. 48, p. 151-169 19 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling

Yan, K. H., Yao, C. J., Hsiao, C. H., Lin, K. H., Lin, Y. W., Wen, Y-C., Liu, C. C., Yan, M. D., Chuang, S. E., Lai, G. M. & Lee, L. M., Oct 2013, In : Oncology Letters. 5, 5, p. 1541-1545 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Mefloquine induces cell death in prostate cancer cells and provides a potential novel treatment strategy in vivo

Yan, K. H., Lin, Y. W., Hsiao, C. H., Wen, Y-C., Lin, K. H., Liu, C. C., Hsieh, M-C., Yao, C. J., Yan, M. D., Lai, G. M., Chuang, S. E. & Lee, L. M., Oct 2013, In : Oncology Letters. 5, 5, p. 1567-1571 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Meningeal carcinomatosis from solid tumors: clinical analysis of 42 cases.

Liaw, C. C., Ng, K. T., Huang, J. S., Wang, C. H., Kiu, M. C. & Lai, G. M., Mar 1992, In : Journal of the Formosan Medical Association = Taiwan yi zhi. 91, 3, p. 299-303 5 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Negative feedback regulation of AXL by miR-34a modulates apoptosis in lung cancer cells

Cho, C. Y., Huang, J. S., Shiah, S. G., Chung, S. Y., Lay, J. D., Yang, Y. Y., Lai, G. M., Cheng, A. L., Chen, L. T. & Chuang, S. E., Feb 1 2016, In : RNA. 22, 2, p. 303-315 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Newly established MST-1 tumour cell line and tumour-infiltrating lymphocyte culture from a patient with soft tissue melanoma (clear cell sarcoma) and their potential applications to patient immunotherapy

Liao, S. K., Perng, Y. P., Lee, L. A., Chang, K. S. S., Lai, G. M., Wong, E. & Ho, Y. S., Feb 1996, In : European Journal of Cancer. 32, 2, p. 346-356 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)