Research Output per year
Research Output
2019
Electrospun polylactic acid (PLLA) microtube array membrane (MTAM)-An advanced substrate for anticancer drug screening
Tseng, C. H., Huang, W. T., Chew, C. H., Lai, J. K., Tu, S. H., Wei, P. L., Lee, K. Y., Lai, G. M. & Chen, C. C., Feb 14 2019, In : Materials. 12, 4, 569.Research output: Contribution to journal › Article
Open Access
2
Citations
(Scopus)
Epigenetic modification and differentiation induction of malignant glioma cells by oligo-fucoidan
Liao, C. H., Lai, I. C., Kuo, H. C., Chuang, S. E., Lee, H. L., Whang-Peng, J., Yao, C. J. & Lai, G. M., Sep 8 2019, In : Marine Drugs. 17, 9, 525.Research output: Contribution to journal › Article
Open Access
Hematuria induced by combination regorafenib and hyperthermia–a radiation recall effect
Zheng, Y. M., Chow, J. M., Chang, C. L., Chao, L. H., Whang-Peng, J. & Lai, G. M., Jan 1 2019, In : International Journal of Hyperthermia. 36, 1, p. 1186-1189 4 p.Research output: Contribution to journal › Letter
Open Access
Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform
Lin, H. S., Huang, Y. L., Wang, Y. R., Hsiao, E., Hsu, T. A., Shiao, H. Y., Jiaang, W. T., Sampurna, B. P., Lin, K. H., Wu, M. S., Lai, G. M. & Yuh, C. H., Jun 1 2019, In : Cancers. 11, 6, 739.Research output: Contribution to journal › Article
Open Access
8
Citations
(Scopus)
Protective effect of Antrodia cinnamomea extract against irradiation-induced acute hepatitis
Kuo, T. H., Kuo, Y. H., Cho, C. Y., Yao, C. J., Lai, G. M. & Chuang, S. E., Feb 2 2019, In : International Journal of Molecular Sciences. 20, 4, 846.Research output: Contribution to journal › Article
Open Access
1
Citation
(Scopus)
PTBP1-mediated regulation of AXL mRNA stability plays a role in lung tumorigenesis
Cho, C. Y., Chung, S. Y., Lin, S., Huang, J. S., Chen, Y. L., Jiang, S. S., Cheng, L. C., Kuo, T. H., Lay, J. D., Yang, Y. Y., Lai, G. M. & Chuang, S. E., Dec 1 2019, In : Scientific Reports. 9, 1, 16922.Research output: Contribution to journal › Article
Open Access
2
Citations
(Scopus)
2018
Human Urine Extract Cell Differentiation Agent 2 Protects PC12 Cells from Serum Deprivation-Induced Apoptosis Accompanied with Priming of Extracellular Signal-Regulated Kinase Activation and Differentiation Induction
Yao, C. J., Chuang, S. E., Yang, Y. Y. & Lai, G. M., Feb 17 2018, (Accepted/In press) In : Chinese Journal of Integrative Medicine. p. 1-7 7 p.Research output: Contribution to journal › Article
Opposite regulation of CHOP and GRP78 and synergistic apoptosis induction by selenium yeast and fish oil via AMPK activation in lung adenocarcinoma cells
Kao, R. H., Lai, G. M., Chow, J. M., Liao, C. H., Zheng, Y. M., Tsai, W. L., Hsia, S., Lai, I. C., Lee, H. L., Chuang, S. E., Whang-Peng, J. & Yao, C. J., Oct 8 2018, In : Nutrients. 10, 10, 1458.Research output: Contribution to journal › Article
1
Citation
(Scopus)
Promoting Physical and Psychological Rehabilitation Activities and Evaluating Potential Links Among Cancer-Related Fatigue, Fear of Recurrence, Quality of Life, and Physiological Indicators in Cancer Survivors
Lee, Y. H., Lai, G. M., Lee, D. C., Tsai Lai, L. J. & Chang, Y. P., Dec 1 2018, In : Integrative Cancer Therapies. 17, 4, p. 1183-1194 12 p.Research output: Contribution to journal › Article
Open Access
2
Citations
(Scopus)
2017
Active fraction (HS7) from Taiwanofungus camphoratus inhibits AKT-mTOR, ERK and STAT3 pathways and induces CDK inhibitors in CL1-0 human lung cancer cells
Lai, I. C., Lai, G. M., Chow, J. M., Lee, H. L., Yeh, C. F., Li, C. H., Yan, J. L., Chuang, S. E., Whang-Peng, J., Bai, K. J. & Yao, C. J., Nov 15 2017, In : Chinese Medicine (United Kingdom). 12, 1, 33.Research output: Contribution to journal › Article
6
Citations
(Scopus)
Corrigendum: Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress
Lee, W. J., Chien, M. H., Chow, J. M., Chang, J. L., Wen, Y. C., Lin, Y. W., Cheng, C. W., Lai, G. M., Hsiao, M. & Lee, L. M., Feb 22 2017, In : Scientific Reports. 7, 1 p.Research output: Contribution to journal › Comment/debate
Open Access
Corrigendum to “RPS12 increases the invasiveness in cervical cancer activated by c-Myc and inhibited by the dietary flavonoids luteolin and quercetin” [J. Funct. Foods (2015) 19PA (236–247)] (S1756464615004478)(10.1016/j.jff.2015.09.030)
Lin, C-W., Lai, G-M., Chen, K-C., Lin, T. H., Fan, J. J., Hsu, R. L., Chou, C-M., Lin, C-M., Kandaswami, C. C., Lee, M. T. & Cheng, C-H., Feb 1 2017, In : Journal of Functional Foods. 29, p. 303 1 p.Research output: Contribution to journal › Comment/debate
Induction of Forkhead Class box O3a and apoptosis by a standardized ginsenoside formulation, KG-135, is potentiated by autophagy blockade in A549 human lung cancer cells
Yao, C. J., Chow, J. M., Chuang, S. E., Chang, C. L., Yan, M. D., Lee, H. L., Lai, I. C., Lin, P. C. & Lai, G. M., Jul 2017, In : Journal of Ginseng Research. 41, 3, p. 247-256Research output: Contribution to journal › Article
14
Citations
(Scopus)
2016
Activation of p53/miR-34a tumor suppressor axis by Chinese herbal formula JP-1 in A549 lung adenocarcinoma cells
Yao, C. J., Chow, J. M., Lin, P. C., Hu, T. S., Kuo, H. C., Huang, J. S., Bai, K. J. & Lai, G. M., 2016, In : Evidence-based Complementary and Alternative Medicine. 2016, 5989681.Research output: Contribution to journal › Article
4
Citations
(Scopus)
Chinese Herbal Mixture, Tien-Hsien Liquid, Induces G2/M Cycle Arrest and Radiosensitivity in MCF-7 Human Breast Cancer Cells through Mechanisms Involving DNMT1 and Rad51 Downregulation
Yao, C. J., Chow, J. M., Yang, C. M., Kuo, H. C., Chang, C. L., Lee, H. L., Lai, I. C., Chuang, S. E. & Lai, G. M., Jan 1 2016, In : Evidence-based Complementary and Alternative Medicine. 2016, 3251046.Research output: Contribution to journal › Article
3
Citations
(Scopus)
Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis induction
Huang, J. S., Yao, C. J., Chuang, S. E., Yeh, C-T., Lee, L. M., Chen, R. M., Chao, W. J., Whang-Peng, J. & Lai, G. M., Mar 24 2016, In : BMC Cancer. 16, 1, 245.Research output: Contribution to journal › Article
19
Citations
(Scopus)
Negative feedback regulation of AXL by miR-34a modulates apoptosis in lung cancer cells
Cho, C. Y., Huang, J. S., Shiah, S. G., Chung, S. Y., Lay, J. D., Yang, Y. Y., Lai, G. M., Cheng, A. L., Chen, L. T. & Chuang, S. E., Feb 1 2016, In : RNA. 22, 2, p. 303-315 13 p.Research output: Contribution to journal › Article
19
Citations
(Scopus)
2015
Elimination of cancer stem-like cells and potentiation of temozolomide sensitivity by honokiol in glioblastoma multiforme cells
Lai, I. C., Shih, P. H., Yao, C-J., Yeh, C-T., Wang-Peng, J., Lui, T-N., Chuang, S. E., Hu, T. S., Lai, T-Y. & Lai, G-M., Mar 12 2015, In : PLoS One. 10, 3, e0114830.Research output: Contribution to journal › Article
14
Citations
(Scopus)
Fucoidan elevates MicroRNA-29b to regulate DNMT3B-MTSS1 axis and inhibit EMT in human hepatocellular carcinoma cells
Yan, M. D., Yao, C. J., Chow, J. M., Chang, C. L., Hwang, P. A., Chuang, S. E., Whang-Peng, J. & Lai, G. M., Oct 1 2015, In : Marine Drugs. 13, 10, p. 6099-6116 18 p.Research output: Contribution to journal › Article
45
Citations
(Scopus)
Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress
Lee, W. J., Chien, M. H., Chow, J. M., Chang, J. L., Wen, Y-C., Lin, Y. W., Cheng, C. W., Lai, G. M., Hsiao, M. & Lee, L. M., May 27 2015, In : Scientific Reports. 5, 10420.Research output: Contribution to journal › Article
32
Citations
(Scopus)
RPS12 increases the invasiveness in cervical cancer activated by c-Myc and inhibited by the dietary flavonoids luteolin and quercetin
Lin, C. W., Lai, G. M., Chen, K. C., Lin, T. H., Fan, J. J., Hsu, R. L., Chou, C. M., Lin, C. M., Kandaswami, C. C., Lee, M. T. & Cheng, C. H., Dec 1 2015, In : Journal of Functional Foods. 19, p. 236-247 12 p.Research output: Contribution to journal › Article
10
Citations
(Scopus)
2014
Elimination of cancer stem-like side population in human glioblastoma cells accompanied with stemness gene suppression by Korean herbal recipe MSC500
Yao, C. J., Han, T. Y., Shih, P. H., Yi, T. Y., Lai, I. C., Chang, K. H., Lai, T-I., Chang, C. L. & Lai, G. M., Nov 19 2014, In : Integrative Cancer Therapies. 13, 6, p. 541-554 14 p.Research output: Contribution to journal › Article
5
Citations
(Scopus)
Erratum: Oxidative stress enhances AXL-mediated cell migration through AKT1/Rac1-dependent mechanism (Free Radical Biology and Medicine (2013) 65 (1246-1256))
Huang, J. S., Cho, C. Y., Hong, C. C., Yan, M. D., Hsieh, M-C., Lay, J. D., Lai, G. M., Ann-Lii, C. & Chuang, S. E., Feb 2014, In : Free Radical Biology and Medicine. 67, p. 416 1 p.Research output: Contribution to journal › Article
Nobiletin suppresses the proliferation and induces apoptosis involving MAPKs and caspase-8/-9/-3 signals in human acute myeloid leukemia cells
Hsiao, P. C., Lee, W-J., Yang, S. F., Tan, P., Chen, H. Y., Lee, L-M., Chang, J. L., Lai, G-M., Chow, J-M. & Chien, M-H., Dec 1 2014, In : Tumor Biology. 35, 12, p. 11903-11911 9 p.Research output: Contribution to journal › Article
23
Citations
(Scopus)
2013
Aspirin antagonizes the cytotoxic effect of methotrexate in lung cancer cells
Yan, K. H., Lee, L. M., Hsieh, M-C., Yan, M. D., Yao, C. J., Chang, P. Y., Chen, T. L., Chang, H. Y., Cheng, A. L., Lai, G. M. & Chuang, S. E., Sep 2013, In : Oncology Reports. 30, 3, p. 1497-1505 9 p.Research output: Contribution to journal › Article
11
Citations
(Scopus)
Honokiol eliminates human oral cancer stem-like cells accompanied with suppression of Wnt/ β -Catenin signaling and apoptosis induction
Yao, C. J., Lai, G. M., Yeh, C-T., Lai, M. T., Shih, P. H., Chao, W. J., Whang-Peng, J., Chuang, S. E. & Lai, T-Y., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 146136.Research output: Contribution to journal › Article
29
Citations
(Scopus)
Honokiol-induced apoptosis and autophagy in glioblastoma multiforme cells
Chang, K. H., Yan, M. D., Yao, C. J., Lin, P. C. & Lai, G. M., Nov 2013, In : Oncology Letters. 6, 5, p. 1435-1438 4 p.Research output: Contribution to journal › Article
45
Citations
(Scopus)
Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling
Yan, K. H., Yao, C. J., Hsiao, C. H., Lin, K. H., Lin, Y. W., Wen, Y-C., Liu, C. C., Yan, M. D., Chuang, S. E., Lai, G. M. & Lee, L. M., Oct 2013, In : Oncology Letters. 5, 5, p. 1541-1545 5 p.Research output: Contribution to journal › Article
15
Citations
(Scopus)
Mefloquine induces cell death in prostate cancer cells and provides a potential novel treatment strategy in vivo
Yan, K. H., Lin, Y. W., Hsiao, C. H., Wen, Y-C., Lin, K. H., Liu, C. C., Hsieh, M-C., Yao, C. J., Yan, M. D., Lai, G. M., Chuang, S. E. & Lee, L. M., Oct 2013, In : Oncology Letters. 5, 5, p. 1567-1571 5 p.Research output: Contribution to journal › Article
13
Citations
(Scopus)
Oxidative stress enhances Axl-mediated cell migration through an Akt1/Rac1-dependent mechanism
Huang, J. S., Cho, C. Y., Hong, C. C., Yan, M. D., Hsieh, M-C., Lay, J. D., Lai, G. M., Cheng, A. L. & Chuang, S. E., 2013, In : Free Radical Biology and Medicine. 65, p. 1246-1256 11 p.Research output: Contribution to journal › Article
28
Citations
(Scopus)
2012
Elimination of cancer stem-like side population cells in hepatoma cell lines by Chinese herbal mixture Tien-Hsien Liquid
Yao, C. J., Yeh, C-T., Lee, L. M., Chuang, S. E., Yeh, C. F., Chao, W. J., Lai, T-I. & Lai, G. M., 2012, In : Evidence-based Complementary and Alternative Medicine. 2012, 617085.Research output: Contribution to journal › Article
16
Citations
(Scopus)
Honokiol traverses the blood-brain barrier and induces apoptosis of neuroblastoma cells via an intrinsic bax-mitochondrion-cytochrome c-caspase protease pathway
Lin, J. W., Chen, J. T., Ye, H-C., Lin, Y. L., Wang, K. T., Yao, C. J., Lai, G. M. & Chen, R. M., Mar 2012, In : Neuro-Oncology. 14, 3, p. 302-314 13 p.Research output: Contribution to journal › Article
71
Citations
(Scopus)
2011
Apoptotic cell death and inhibition of Wnt/ β-catenin signaling pathway in human colon cancer cells by an active fraction (hs7) from taiwanofungus camphoratus
Yeh, C-T., Yao, C. J., Yan, J. L., Chuang, S. E., Lee, L. M., Chen, C-M., Yeh, C. F., Li, C. H. & Lai, G. M., 2011, In : Evidence-based Complementary and Alternative Medicine. 2011, 750230.Research output: Contribution to journal › Article
22
Citations
(Scopus)
Targeting PML-RARα and oncogenic signaling pathways by Chinese herbal mixture Tien-Hsien liquid in acute promyelocytic leukemia NB4 cells
Lai, T-I., Yao, C. J., Yang, C. M., Chuang, S. E., Yan, J. L., Liu, C. Y., Chen, S. W., Yan, K. H. & Lai, G. M., 2011, In : Evidence-based Complementary and Alternative Medicine. 2011, 984154.Research output: Contribution to journal › Article
10
Citations
(Scopus)
2010
The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells
Yan, K. H., Yao, C. J., Chang, H. Y., Lai, G. M., Cheng, A. L. & Chuang, S. E., Mar 2010, In : Molecular Carcinogenesis. 49, 3, p. 235-246 12 p.Research output: Contribution to journal › Article
32
Citations
(Scopus)
2009
Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells
Yeh, C. T., Rao, Y. K., Yao, C. J., Yeh, C. F., Li, C. H., Chuang, S. E., Luong, J. H. T., Lai, G. M. & Tzeng, Y. M., Nov 18 2009, In : Cancer Letters. 285, 1, p. 73-79 7 p.Research output: Contribution to journal › Article
89
Citations
(Scopus)
2008
Carbonic anhydrase III promotes transformation and invasion capability in hepatoma cells through FAK signaling pathway
Dai, H. Y., Hong, C. C., Liang, S. C., Yan, M. D., Lai, G. M., Cheng, A. L. & Chuang, S. E., Dec 2008, In : Molecular Carcinogenesis. 47, 12, p. 956-963 8 p.Research output: Contribution to journal › Article
24
Citations
(Scopus)
Receptor tyrosine kinase AXL is induced by chemotherapy drugs and overexpression of AXL confers drug resistance in acute myeloid leukemia
Hong, C. C., Lay, J. D., Huang, J. S., Cheng, A. L., Tang, J. L., Lin, M. T., Lai, G. M. & Chuang, S. E., Sep 18 2008, In : Cancer Letters. 268, 2, p. 314-324 11 p.Research output: Contribution to journal › Article
128
Citations
(Scopus)
2007
Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells
Chen, C. N., Huang, H. H., Wu, C. L., Lin, C. P. C., Hsu, J. T. A., Hsieh, H. P., Chuang, S. E. & Lai, G. M., Feb 8 2007, In : Cancer Letters. 246, 1-2, p. 237-252 16 p.Research output: Contribution to journal › Article
53
Citations
(Scopus)
Sulfasalazine suppresses drug resistance and invasiveness of lung adenocarcinoma cells expressing AXL
Lay, J. D., Hong, C. C., Huang, J. S., Yang, Y. Y., Pao, C. Y., Liu, C. H., Lai, Y. P., Lai, G. M., Cheng, A. L., Su, I. J. & Chuang, S. E., Apr 15 2007, In : Cancer Research. 67, 8, p. 3878-3887 10 p.Research output: Contribution to journal › Article
70
Citations
(Scopus)
2006
Dramatic synergistic anticancer effect of clinically achievable doses of lovastatin and troglitazone
Yao, C. J., Lai, G. M., Chan, C. F., Cheng, A. L., Yang, Y. Y. & Chuang, S. E., Mar 1 2006, In : International Journal of Cancer. 118, 3, p. 773-779 7 p.Research output: Contribution to journal › Article
60
Citations
(Scopus)
2005
Differentiation of pheochromocytoma PC 12 cells induced by human urine extract and the involvement of the extracellular signal-regulated kinase signaling pathway
Yao, C. J., Lai, G. M., Chan, C. F., Yang, Y. Y., Liu, F. C. & Chuang, S. E., Oct 2005, In : Journal of Alternative and Complementary Medicine. 11, 5, p. 903-908 6 p.Research output: Contribution to journal › Article
11
Citations
(Scopus)
Identification and characterization of a novel gene Saf transcribed from the opposite strand of Fas
Yan, M. D., Hong, C. C., Lai, G. M., Cheng, A. L., Lin, Y. W. & Chuang, S. E., Jun 1 2005, In : Human Molecular Genetics. 14, 11, p. 1465-1474 10 p.Research output: Contribution to journal › Article
73
Citations
(Scopus)
2002
Basal levels and patterns of anticancer drug-induced activation of nuclear factor-κB (NF-κB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells
Chuang, S. E., Yeh, P. Y., Lu, Y. S., Lai, G. M., Liao, C. M., Gao, M. & Cheng, A. L., May 1 2002, In : Biochemical Pharmacology. 63, 9, p. 1709-1716 8 p.Research output: Contribution to journal › Article
140
Citations
(Scopus)
Expression of epidermal growth factor receptor in head and neck cancers correlates with clinical progression: A multicentre immunohistochemical study in the Asia-Pacific region
Putti, T. C., To, K. F., Hsu, H. C., Chan, A. T. C., Lai, G. M., Tse, G., Lee, Y. S., Whang-Peng, J., Millward, M., Lin, L., Lin, X. & Lee, C. S., 2002, In : Histopathology. 41, 2, p. 144-151 8 p.Research output: Contribution to journal › Article
61
Citations
(Scopus)
2000
Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis
Chuang, S. E., Kuo, M. L., Hsu, C. H., Chen, C. R., Lin, J. K., Lai, G. M., Hsieh, C. Y. & Cheng, A. L., 2000, In : Carcinogenesis. 21, 2, p. 331-335 5 p.Research output: Contribution to journal › Article
215
Citations
(Scopus)
1998
Malignant thyroid teratoma of an adult: A long-term survival after chemotherapy
Chen, J. S., Lai, G. M. & Hsueh, S., Apr 1998, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 21, 2, p. 212-214 3 p.Research output: Contribution to journal › Article
12
Citations
(Scopus)
1997
Intensive Chemotherapy plus Recombinant Human Granulocyte Colony Stimulating Factor Support for Distant Metastatic Nasopharyngeal Carcinoma
Wang, C. H., Wang, H. M., Chen, J. S., Chang, W. J. & Lai, G. M., Jan 1997, In : Oncology. 54, SUPPL. 1, p. 34-37 4 p.Research output: Contribution to journal › Article
4
Citations
(Scopus)
Weekly CAF chemotherapy for advanced breast cancer patients
Hwang, W. S., Hsiung, C. A., Ko, W. S., Wang, C. C., Chang, J. Y., Lai, G. M., Hsieh, R. K., Tsao, C. J., Chen, L. T., Law, C. K., Cheng, A. L., Fan, S. F., Tzeng, C. H., Chiou, T. J. & Whang-Peng, J., Jul 1997, In : Oncology. 54, 4, p. 293-297 5 p.Research output: Contribution to journal › Article
1
Citation
(Scopus)
1996
Clinical trial of low-dose rHuG-CSF in neutropenic cancer patients following anti-cancer chemotherapy
Chang, M. C., Lai, G. M., Tsan, K. W., Wang, R. S. & Wu, J. H., Nov 1996, In : Journal of the Formosan Medical Association = Taiwan yi zhi. 95, 11, p. 845-850 6 p.Research output: Contribution to journal › Article
1
Citation
(Scopus)