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Personal profile

Education

  • 1991-1996 Ph.D., Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan
  • 1989-1991 M.S., Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan
  • 1984-1989 B.S., School of Pharmacy, China Medical College, Taichung, Taiwan

Experience

  • 2019- Director, Department of Pharmacology, School of Medicine, Taipei Medical University
  • 2016-2017 Professor of Ph.D Program in Biotechnology Research and Development, Taipei Medical University
  • 2014- Chairman, Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University /Division of Molecular Pharmacology of Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University
  • 2008- Professor, Department of Pharmacology, School of Medicine and Division of Molecular Pharmacology of Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University
  • 2011-2013 Adjunct Professor, School of Medicine, College of Medicine, Mackay Medical College
  • 2003-2008, Associate Professor, Department of Pharmacology, School of Medicine and Institute of Pharmacology, College of Medicine, Taipei Medical University
  • 2006 Visiting Research Scholar, Cardiovascular Laboratory, Department of Physiology, Medical College of Georgia, USA
  • 1999-2002 Assistant Professor, Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University
  • 1998-1999 Instructor and Postdoctorial, Department of Pharmacology, National Defense Medical College
  • 1997 Postdoctorial, Department of Pharmacology, National Taiwan University

Research Interests

  • Signal transductions in human monocytes /microglia (phagocytes), pulmonary cells, intestine epithelial cells and tumor cells (AML, chondrosarcoma, and hepatoma )
  • Mechanisms of epigenetic, redox-regulatory of anti-matrix metalloproteinase agents
  • Drug evaluation and discovery on anti-inflammatory, anti-retinal dysfunction and anti-stroke drugs

Awards

  • The Most Influential Paper Award, TMU, Taiwan (2014)
  • The Major Research Program Award, TMU, Taiwan (2012-2013)
  • Research Award, NSC, Taiwan (1999-2002)
  • Excellent Thesis Award, College of Medicine, NTU, Taiwan (1996)

Fingerprint Dive into the research topics where George Hsiao is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Blood Platelets Medicine & Life Sciences
Platelets Chemical Compounds
Platelet Aggregation Medicine & Life Sciences
Chemical activation Chemical Compounds
Platelet Activation Medicine & Life Sciences
Matrix Metalloproteinase 9 Medicine & Life Sciences
Rats Chemical Compounds
Phosphorylation Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2020

探討真菌衍生之抗神經發炎成分及其對視網膜疾病之療效評估(2/3)

Hsiao, G.

8/1/197/1/20

Project: A - Government Institutionb - Ministry of Science and Technology

107大專生計畫獎-蕭哲志

Hsiao, G.

8/1/187/31/19

Project: A - Government Institutionb - Ministry of Science and Technology

探討真菌衍生之抗神經發炎成分及其對視網膜疾病之療效評估(1/3)

Hsiao, G.

8/1/187/1/19

Project: A - Government Institutionb - Ministry of Science and Technology

Research Output 1996 2019

  • 3650 Citations
  • 34 h-Index
  • 140 Article
  • 4 Erratum
  • 1 Poster
  • 1 Meeting Abstract

HDAC8 inhibitor WK2-16 therapeutically targets lipopolysaccharide-induced mouse model of neuroinflammation and microglial activation

Lin, F. L., Yen, J. L., Kuo, Y. C., Kang, J. J., Cheng, Y. W., Huang, W. J. & Hsiao, G., Jan 2 2019, In : International Journal of Molecular Sciences. 20, 2, p. 410 410.

Research output: Contribution to journalArticle

Neuroglia
inhibitors
mice
Lipopolysaccharides
Chemical activation

Hirsutanol A attenuates lipopolysaccharide-mediated matrix metalloproteinase 9 expression and cytokines production and improves endotoxemia-induced acute sickness behavior and acute lung injury

Jan, J. S., Yang, C. H., Wang, M. H., Lin, F. L., Yen, J. L., Hsieh, I., Khotimchenko, M., Lee, T. H. & Hsiao, G., Jun 17 2019, In : Marine Drugs. 17, 6, 360.

Research output: Contribution to journalArticle

Open Access
Illness Behavior
Endotoxemia
Acute Lung Injury
Matrix Metalloproteinase 9
Lipopolysaccharides

Low-luminance blue light-enhanced phototoxicity in A2E-Laden RPE cell cultures and rats

Lin, C. H., Wu, M. R., Huang, W. J., Chow, D. S. L., Hsiao, G. & Cheng, Y. W., Apr 1 2019, In : International Journal of Molecular Sciences. 20, 7, 1799.

Research output: Contribution to journalArticle

Open Access
Phototoxic Dermatitis
Retinal Pigments
luminance
pigments
Cell culture

The fungus-derived retinoprotectant theissenolactone C improves glaucoma-like injury mediated by MMP-9 inhibition

Lin, F. L., Cheng, Y. W., Yu, M., Ho, J. D., Kuo, Y. C., Chiou, G. C. Y., Chang, H. M., Lee, T. H. & Hsiao, G., Mar 15 2019, In : Phytomedicine. 56, p. 207-214 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 9
Glaucoma
Reperfusion Injury
Interleukin-1
Chemokine CCL2
1 Citation (Scopus)

Haloperidol Abrogates Matrix Metalloproteinase-9 Expression by Inhibition of NF-κB Activation in Stimulated Human Monocytic Cells

Lee, Y. L., Hsiao, C. J., Lin, F. L., Jan, J. S., Chou, Y. C., Lin, Y. Y., Chen, C. K., Lam, K. K. & Hsiao, G., Jan 1 2018, In : Mediators of Inflammation. 2018, 1 p., 9541459.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 9
Haloperidol
Matrix Metalloproteinases
Lipopolysaccharides
Tumor Necrosis Factor-alpha