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Research Output 2001 2019

  • 2557 Citations
  • 29 h-Index
  • 104 Article
2019

B-type natriuretic peptide enhances fibrotic effects via matrix metalloproteinase-2 expression in the mouse atrium in vivo and in human atrial myofibroblasts in vitro

Tsai, Y. T., Lin, F. Y., Lin, C. S., Loh, S. H., Li, C. Y., Lin, C. Y., Lin, Y. W. & Tsai, C. S., Jan 1 2019, In : Translational Research.

Research output: Contribution to journalArticle

Myofibroblasts
Brain Natriuretic Peptide
Matrix Metalloproteinase 2
Fibrosis
Protein Stability

DAPT Plus Cilostazol is Better Than Traditional DAPT or Aspirin Plus Ticagrelor as Elective PCI for Intermediate-to-Highly Complex Cases: Prospective, Randomized, PRU-Based Study in Taiwan

Chen, Y. C., Lin, F. Y., Lin, Y. W., Cheng, S. M., Lin, R. H., Chuang, C. L., Sheu, J. S., Chen, S. M., Chang, C. C. & Tsai, C. S., Feb 12 2019, In : American Journal of Cardiovascular Drugs. 19, 1, p. 75-86 12 p.

Research output: Contribution to journalArticle

clopidogrel
Taiwan
Aspirin
Blood Platelets
Stents

Dysfunctional high density lipoprotein failed to rescue the function of oxidized low density lipoprotein-treated endothelial progenitor cells: a novel index for the prediction of HDL functionality

Shih, C. M., Lin, F. Y., Yeh, J. S., Lin, Y. W., Loh, S. H., Tsao, N. W., Nakagami, H., Morishita, R., Sawamura, T., Li, C. Y., Lin, C. Y. & Huang, C. Y., Mar 1 2019, In : Translational Research. 205, p. 17-32 16 p.

Research output: Contribution to journalArticle

Endothelial cells
HDL Lipoproteins
Assays
Dyslipidemias
Atherosclerosis

Microbial etiology of pneumonia in patients with decreased renal function

Chen, C. Y., Hsu, S. C., Hsieh, H. L., Suk, C. W., Hsu, Y. P., Sue, Y. M., Chen, T. H., Lin, F. Y., Shih, C. M., Chen, J. W., Lin, S. J., Huang, P. H. & Liu, C. T., May 1 2019, In : PLoS One. 14, 5, e0216367.

Research output: Contribution to journalArticle

Open Access
renal function
pneumonia
Lymphocytes
etiology
Pneumonia
2 Citations (Scopus)

Platelet MicroRNA 365-3p Expression Correlates with High On-treatment Platelet Reactivity in Coronary Artery Disease Patients

Chen, Y. C., Lin, F. Y., Lin, Y. W., Cheng, S. M., Chang, C. C., Lin, R. H., Chuang, C. L., Sheu, J. S., Chen, S. M. & Tsai, C. S., Jan 1 2019, In : Cardiovascular Drugs and Therapy.

Research output: Contribution to journalArticle

MicroRNAs
Coronary Artery Disease
Blood Platelets
clopidogrel
Therapeutics

Point of Care eGFR and the Prediction of Outcomes in Pneumonia

Suk, C. W., Hsu, S. C., Chen, C. Y., Hsieh, H. L., Kuo, H. T., Hsu, Y. P., Sue, Y. M., Chen, T. H., Lin, F. Y., Shih, C. M., Chen, J. W., Lin, S. J., Huang, P. H. & Liu, C. T., Dec 1 2019, In : Scientific Reports. 9, 1, 8478.

Research output: Contribution to journalArticle

Open Access
Point-of-Care Systems
Glomerular Filtration Rate
Pneumonia
Mortality
Intensive Care Units
2 Citations (Scopus)

RNA-binding protein, human antigen R regulates hypoxia-induced autophagy by targeting ATG7/ATG16L1 expressions and autophagosome formation

Palanisamy, K., Tsai, T. H., Yu, T. M., Sun, K. T., Yu, S. H., Lin, F. Y., Wang, I. K. & Li, C. Y., 2019, In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Autophagy
AU Rich Elements
RNA
Apoptosis
2018
7 Citations (Scopus)
Atrial Fibrillation
Safety
Hemorrhage
Myocardial Infarction
Rivaroxaban

Eotaxin-2 induces monocytic apoptosis in patients who have undergone coronary artery bypass surgery and in THP-1 cells in vitro regulated by thrombomodulin

Lin, Y. W., Huang, C. Y., Shih, C. M., Tsai, Y. T., Lin, C. S., Lin, C. Y., Li, C. Y., Loh, S. H., Lin, C. Y., Lin, F. Y. & Tsai, C. S., Jan 1 2018, In : American Journal of Translational Research. 10, 10, p. 3133-3149 17 p., AJTR0081221.

Research output: Contribution to journalArticle

Chemokine CCL24
Thrombomodulin
Coronary Artery Bypass
Surgery
Apoptosis
2017
3 Citations (Scopus)
Dipeptidyl Peptidase 4
Abdominal Aortic Aneurysm
Monocytes
Cell Differentiation
Adventitia
7 Citations (Scopus)

Risk of Febuxostat-Associated myopathy in patients with CKD

Liu, C. T., Chen, C. Y., Hsu, C. Y., Huang, P. H., Lin, F. Y., Chen, J. W. & Lin, S. J., 2017, In : Clinical Journal of the American Society of Nephrology. 12, 5, p. 744-750 7 p.

Research output: Contribution to journalArticle

Muscular Diseases
Rhabdomyolysis
Creatine Kinase
Febuxostat
Confidence Intervals
5 Citations (Scopus)

Synthetic fluororutaecarpine inhibits inflammatory stimuli and activates endothelial transient receptor potential vanilloid-type 1

Lee, C-M., Gu, J. A., Rau, T. G., Wang, C., Yen, C. H., Huang, S. H., Lin, F. Y., Lin, C. M. & Huang, S. T., Apr 1 2017, In : Molecules. 22, 4, 656.

Research output: Contribution to journalArticle

vasodilation
macrophages
Macrophages
nitric oxide
Cytotoxicity
2016
5 Citations (Scopus)

Cancer incidence among heart, kidney, and liver transplant recipients in Taiwan

Lee, K. F., Tsai, Y. T., Lin, C. Y., Hsieh, C. B., Wu, S. T., Ke, H. Y., Lin, Y. C., Lin, F. Y., Lee, W. H. & Tsai, C. S., May 1 2016, In : PLoS One. 11, 5, e0155602.

Research output: Contribution to journalArticle

heart transplant
liver transplant
kidney transplant
Transplants
Taiwan
18 Citations (Scopus)

Coenzyme Q10 Attenuates High Glucose-Induced Endothelial Progenitor Cell Dysfunction through AMP-Activated Protein Kinase Pathways

Tsai, H. Y., Lin, C. P., Huang, P. H., Li, S. Y., Chen, J. S., Lin, F. Y., Chen, J. W. & Lin, S. J., 2016, In : Journal of Diabetes Research. 2016, 6384759.

Research output: Contribution to journalArticle

coenzyme Q10
AMP-Activated Protein Kinases
Glucose
Heme Oxygenase-1
Apoptosis
2 Citations (Scopus)

Eotaxin-2 increased toll-like receptor 4 expression in endothelial cells in vitro and exacerbates high-cholesterol diet-induced atherogenesis in vivo

Tsai, C. S., Huang, C. Y., Chen, C. H., Lin, Y. W., Shih, C. M., Tsao, N. W., Chiang, K. H., Lee, C. Y., Jeng, H. & Lin, F. Y., 2016, In : American Journal of Translational Research. 8, 12, p. 5338-5353 16 p.

Research output: Contribution to journalArticle

Chemokine CCL24
Toll-Like Receptor 4
Endothelial cells
Nutrition
Atherosclerosis
1 Citation (Scopus)

Maspin mediates the gemcitabine sensitivity of hormone-independent prostate cancer

Huang, C. Y., Chang, Y. J., Luo, S. D., Uyanga, B., Lin, F. Y., Tai, C. J. & Huang, M. T., Mar 1 2016, In : Tumor Biology. 37, 3, p. 4075-4082

Research output: Contribution to journalArticle

gemcitabine
Prostatic Neoplasms
Hormones
B-Cell Lymphoma
Apoptosis
8 Citations (Scopus)

The GroEL protein of Porphyromonas gingivalis regulates atherogenic phenomena in endothelial cells mediated by upregulating toll-like receptor 4 expression

Huang, C. Y., Shih, C. M., Tsao, N. W., Lin, Y. W., Shih, C. C., Chiang, K. H., Shyue, S. K., Chang, Y. J., Hsieh, C. K. & Lin, F. Y., 2016, In : American Journal of Translational Research. 8, 2, p. 384-404 21 p.

Research output: Contribution to journalArticle

Chaperonin 60
Porphyromonas gingivalis
Toll-Like Receptor 4
Endothelial cells
Endothelial Cells
3 Citations (Scopus)

Thrombomodulin regulates monocye differentiation via PKCÎ and ERK1/2 pathway in vitro and in atherosclerotic artery

Tsai, C. S., Lin, Y. W., Huang, C-Y., Shih, C-M., Tsai, Y. T., Tsao, N-W., Lin, C. S., Shih, C. C., Jeng, H. & Lin, F-Y., Dec 2 2016, In : Scientific Reports. 6, 38421.

Research output: Contribution to journalArticle

Thrombomodulin
MAP Kinase Signaling System
Protein Kinase C
Arteries
Monocytes
2015
5 Citations (Scopus)
Vascular Stiffness
Coronary Artery Disease
Coronary Vessels
Atherosclerotic Plaques
Compliance
2 Citations (Scopus)
U937 Cells
Toll-Like Receptor 4
Down-Regulation
Bone and Bones
MicroRNAs
21 Citations (Scopus)

Dipeptidyl peptidase-4 inhibitor decreases abdominal aortic aneurysm formation through GLP-1-dependent monocytic activity in mice

Lu, H. Y., Huang, C. Y., Shih, C. M., Chang, W. H., Tsai, C. S., Lin, F. Y. & Shih, C. C., Apr 14 2015, In : PLoS One. 10, 4, e0121077.

Research output: Contribution to journalArticle

Dipeptidyl-Peptidase IV Inhibitors
glucagon-like peptide 1
aneurysm
Glucagon-Like Peptide 1
peptidases
10 Citations (Scopus)

Glucose-regulated protein 78 mediates the anticancer efficacy of shikonin in hormone-refractory prostate cancer cells

Kuo, L. J., Huang, C. Y., Cheng, W. L., Hung, C. S., Wu, C. T., Lin, F. Y., Chang, Y. J. & Huang, M. T., Jul 29 2015, In : Tumor Biology. 36, 7, p. 5063-5070 8 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Hormones
Small Interfering RNA
Therapeutics
shikonin
1 Citation (Scopus)

Matrix metalloproteinase-9 production following cardiopulmonary bypass was not associated with pulmonary dysfunction after cardiac surgery

Lin, T. C., Lin, F. Y., Lin, Y. W., Hsu, C. H., Huang, G. S., Wu, Z. F., Tsai, Y. T., Lin, C. Y., Li, C. Y. & Tsai, C. S., 2015, In : Mediators of Inflammation. 2015, 341740.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 9
Cardiopulmonary Bypass
Thoracic Surgery
Lung
Neutrophils
22 Citations (Scopus)

MiR-20a-5p mediates hypoxia-induced autophagy by targeting ATG16L1 in ischemic kidney injury

Wang, I. K., Sun, K. T., Tsai, T. H., Chen, C. W., Chang, S. S., Yu, T. M., Yen, T. H., Lin, F. Y., Huang, C. C. & Li, C. Y., Jul 27 2015, In : Life Sciences. 136, p. 133-141 9 p., 14437.

Research output: Contribution to journalArticle

Autophagy
MicroRNAs
Hypoxia-Inducible Factor 1
Kidney
Wounds and Injuries
3 Citations (Scopus)

Nickel ions from a corroded cardiovascular stent induce monocytic cell apoptosis: Proposed impact on vascular remodeling and mechanism

Shih, C-M., Huang, C-Y., Liao, L. R., Hsu, C. P., Tsao, N-W., Wang, H. S., Chen, W. Y., Su, Y. Y., Lin, S. J., Shih, C. C. & Lin, F-Y., Nov 1 2015, In : Journal of the Formosan Medical Association = Taiwan yi zhi. 114, 11, p. 1088-1096 9 p.

Research output: Contribution to journalArticle

Nickel
Stents
Cell Death
Ions
Apoptosis
16 Citations (Scopus)

Statins, HMG-CoA reductase inhibitors, improve neovascularization by increasing the expression density of CXCR4 in endothelial progenitor cells

Chiang, K. H., Cheng, W. L., Shih, C. M., Lin, Y. W., Tsao, N. W., Kao, Y. T., Lin, C. T., Wu, S. C., Huang, C. Y. & Lin, F. Y., Aug 26 2015, In : PLoS One. 10, 8, e0136405.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Angiogenesis Inhibitors
Endothelial cells
angiogenesis
endothelial cells
16 Citations (Scopus)

The biphasic effects of oxidized-low density lipoprotein on the vasculogenic function of endothelial progenitor cells

Lin, F. Y., Tsao, N. W., Shih, C. M., Lin, Y. W., Yeh, J. S., Chen, J. W., Nakagami, H., Morishita, R., Sawamura, T. & Huang, C. Y., May 1 2015, In : PLoS One. 10, 5, 0123971.

Research output: Contribution to journalArticle

Endothelial cells
low density lipoprotein
endothelial cells
stem cells
p38 Mitogen-Activated Protein Kinases
8 Citations (Scopus)

The GroEL protein of Porphyromonas gingivalis accelerates tumor growth by enhancing endothelial progenitor cell function and neovascularization

Lin, F. Y., Huang, C. Y., Lu, H. Y., Shih, C. M., Tsao, N. W., Shyue, S. K., Lin, C. Y., Chang, Y. J., Tsai, C. S., Lin, Y. W. & Lin, S. J., Jun 1 2015, In : Molecular Oral Microbiology. 30, 3, p. 198-216 19 p.

Research output: Contribution to journalArticle

Chaperonin 60
Porphyromonas gingivalis
Growth
Periodontal Diseases
Neoplasms
2014
7 Citations (Scopus)
Toll-Like Receptor 4
Calpain
Hemostatics
Thoracic Surgery
Blood Platelets
1 Citation (Scopus)
Extracorporeal Membrane Oxygenation
Renal Replacement Therapy
Cardiogenic Shock
Acute Kidney Injury
Survival
18 Citations (Scopus)

MK-0626, a dipeptidyl peptidase-4 inhibitor, improves neovascularization by increasing both the number of circulating endothelial progenitor cells and endothelial nitric oxide synthetase expression

Shih, C. M., Chen, Y. H., -Lin, Y. W., Tsao, N. W., Wu, S. C., Kao, Y. T., Chiang, K. H., Li, C. Y., Chang, N. C., Lin, C. Y., Huang, C. Y. & Lin, F. Y., 2014, In : Current Medicinal Chemistry. 21, 17, p. 2012-2022 11 p.

Research output: Contribution to journalArticle

Dipeptidyl-Peptidase IV Inhibitors
Endothelial cells
Nitric Oxide Synthase
Nitric Oxide Synthase Type III
Ischemia
14 Citations (Scopus)

Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats

Lin, F. Y., Hsiao, F. P., Huang, C. Y., Shih, C. M., Tsao, N. W., Tsai, C. S., Yang, S. F., Chang, N. C., Hung, S. L. & Lin, Y. W., Jul 24 2014, In : PLoS One. 9, 7, e102450.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Alveolar Bone Loss
Periodontal Ligament
bone resorption
Ligaments
3 Citations (Scopus)

The C-terminal domain of thrombomodulin regulates monocyte migration with interleukin-6 stimulation

Lin, Y. W., Huang, C. Y., Shih, C. M., Chang, W. L., Shyue, S. K., Tsai, Y. T., Lin, C. Y., Lee, C. Y., Chang, Y. J., Chang, N. C., Lin, F. Y. & Tsai, C. S., 2014, In : European Journal of Inflammation. 12, 1, p. 27-39 13 p.

Research output: Contribution to journalArticle

Thrombomodulin
Monocytes
Interleukin-6
Actins
Actin Depolymerizing Factors
15 Citations (Scopus)

The role of calpain-myosin 9-Rab7b pathway in mediating the expression of toll-like receptor 4 in platelets: A novel mechanism involved in α-granules trafficking

Tsai, J. C., Lin, Y. W., Huang, C. Y., Lin, C. Y., Tsai, Y. T., Shih, C. M., Lee, C. Y., Chen, Y. H., Li, C. Y., Chang, N. C., Lin, F. Y. & Tsai, C. S., Jan 28 2014, In : PLoS One. 9, 1, e85833.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
calpain
Calpain
thrombin
Myosins
4 Citations (Scopus)

The status of heart transplantation in Taiwan, 2005-2010

Lee, K. F., Lin, C. Y., Tsai, Y. T., Lee, C. Y., Hsu, P. S., Lin, Y. C., Yang, H. Y., Kao, C. H., Song, J. Y., Sung, S. Y., Lin, F. Y., Lee, W. H. & Tsai, C. S., 2014, In : Transplantation Proceedings. 46, 3, p. 934-936 3 p.

Research output: Contribution to journalArticle

Heart Transplantation
Taiwan
Tissue Donors
Registries
Tissue and Organ Procurement
9 Citations (Scopus)

Thrombomodulin mediates the migration of cervical cancer cells through the regulation of epithelial-mesenchymal transition biomarkers

Tai, C-J., Cheng, C-W., Su, H. Y., Chen, W-Y., Wu, C. T., Lin, F-Y., Wang, C. K., Tai, C-J. & Wei, P-L., Jan 2014, In : Tumor Biology. 35, 1, p. 47-54 8 p.

Research output: Contribution to journalArticle

Thrombomodulin
Epithelial-Mesenchymal Transition
Uterine Cervical Neoplasms
Biomarkers
HeLa Cells
2013
Coronary Vessels
Angiography
Tomography
Calcium
Population
Coronary Angiography
Coronary Vessels
Angiography
Tomography
Calcium
49 Citations (Scopus)

Endothelial progenitor cell dysfunction in cardiovascular diseases: Role of reactive oxygen species and inflammation

Lin, C. P., Lin, F. Y., Huang, P. H., Chen, Y. L., Chen, W. C., Chen, H. Y., Huang, Y. C., Liao, W. L., Huang, H. C., Liu, P. L. & Chen, Y. H., 2013, In : BioMed Research International. 2013, 845037.

Research output: Contribution to journalArticle

Endothelial cells
Oxidative stress
Reactive Oxygen Species
Cardiovascular Diseases
Inflammation
18 Citations (Scopus)
Ginkgo biloba
Heme Oxygenase-1
MAP Kinase Signaling System
Nitric Oxide Synthase Type III
Cell Adhesion Molecules
8 Citations (Scopus)

GroEL1, a heat shock protein 60 of Chlamydia pneumoniae, impairs neovascularization by decreasing endothelial progenitor cell function

Lin, Y. W., Huang, C-Y., Chen, Y. H., Shih, C-M., Tsao, N-W., Lin, F. Y., Chang, N-C., Tsai, C. S., Tsai, H. Y., Tsai, J. C., Huang, P. H., Li, C. Y. & Lin, F-Y., Dec 23 2013, In : PLoS One. 8, 12, e84731.

Research output: Contribution to journalArticle

Chlamydophila pneumoniae
Chaperonin 60
Endothelial cells
angiogenesis
heat shock proteins
4 Citations (Scopus)

Low-cytotoxic synthetic bromorutaecarpine exhibits anti-inflammation and activation of transient receptor potential vanilloid type 1 activities

Lee, C-M., Gu, J. A., Rau, T. G., Yang, C. H., Yang, W. C., Huang, S. H., Lin, F. Y., Lin, C. M. & Huang, S. T., 2013, In : BioMed Research International. 2013, 795095.

Research output: Contribution to journalArticle

Chemical activation
Inflammation
Cytotoxicity
Lipopolysaccharides
Evodia
3 Citations (Scopus)

Relation between fetuin-A levels and fibroblast growth factor 23 with the severity of coronary artery disease measured by SYNTAX scores

Chen, Y. C., Lin, F. Y., Lin, R. H., Chuang, C. L., Chang, C. C. & Tsai, C. S., Oct 1 2013, In : American Journal of Cardiology. 112, 7, p. 950-953 4 p.

Research output: Contribution to journalArticle

alpha-2-HS-Glycoprotein
Coronary Artery Disease
Multivariate Analysis
Perfusion
Cholesterol

Subacute bacterial endocarditis presenting as left upper quadrant abdominal pain

Kao, Y. T., Shih, C. M., Tsao, N. W., Lin, F. Y., Chang, N. C. & Huang, C. Y., Sep 2013, In : Journal of the Chinese Medical Association. 76, 9, p. 521-523 3 p.

Research output: Contribution to journalArticle

Subacute Bacterial Endocarditis
Abdominal Pain
Fever
Heart Murmurs
Anorexia
23 Citations (Scopus)

Testosterone replacement therapy can increase circulating endothelial progenitor cell number in men with late onset hypogonadism

Liao, C. H., Wu, Y. N., Lin, F. Y., Tsai, W. K., Liu, S. P. & Chiang, H-S., 2013, In : Andrology. 1, 4, p. 563-569 7 p.

Research output: Contribution to journalArticle

Hypogonadism
Testosterone
Cell Count
Therapeutics
Endothelial Progenitor Cells
1 Citation (Scopus)

Thrombomodulin gene polymorphism (C1418T) is associated with the development of coronary allograft vasculopathy

Tsai, C. S., Lin, Y. W., Shih, C. C., Chen, Y. H., Lin, C. Y., Tsai, Y. T., Lee, C. Y., Shih, C. M., Huang, C. Y., Chung, H. H. & Lin, F. Y., Sep 2013, In : European Journal of Inflammation. 11, 3, p. 685-696 12 p.

Research output: Contribution to journalArticle

Thrombomodulin
Allografts
Genotype
Genes
Heart Transplantation
2012
9 Citations (Scopus)

Androgens inhibit tumor necrosis factor-α-induced cell adhesion and promote tube formation of human coronary artery endothelial cells

Liao, C. H., Lin, F. Y., Wu, Y. N. & Chiang, H-S., Jun 2012, In : Steroids. 77, 7, p. 756-764 9 p.

Research output: Contribution to journalArticle

Cell adhesion
Endothelial cells
Cell Adhesion
Androgens
Testosterone
1 Citation (Scopus)

An endoluminal aortic prosthesis infection presenting as pneumoaorta and aortoduodenal fistula

Kao, Y. T., Shih, C-M., Lin, F-Y., Tsao, N-W., Chang, N-C. & Huang, C-Y., 2012, In : World Journal of Gastroenterology. 18, 37, p. 5309-5311 3 p.

Research output: Contribution to journalArticle

Prostheses and Implants
Fistula
Stents
Transplants
Septic Shock
53 Citations (Scopus)

Dipeptidyl peptidase-4 inhibitor improves neovascularization by increasing circulating endothelial progenitor cells

Huang, C-Y., Shih, C-M., Tsao, N-W., Lin, Y. W., Huang, P. H., Wu, S. C., Lee, A-W., Kao, Y. T., Chang, N-C., Nakagami, H., Morishita, R., Ou, K-L., Hou, W-C., Lin, C. Y., Shyu, K-G. & Lin, F-Y., Dec 2012, In : British Journal of Pharmacology. 167, 7, p. 1506-1519 14 p.

Research output: Contribution to journalArticle

Dipeptidyl-Peptidase IV Inhibitors
Ischemia
Inbred ICR Mouse
Extremities
Hindlimb
73 Citations (Scopus)
Extracorporeal Membrane Oxygenation
Cardiogenic Shock
Percutaneous Coronary Intervention
Myocardial Infarction
Survival