• 711 Citations
  • 13 h-Index
20072020
If you made any changes in Pure these will be visible here soon.

Research Output 2007 2019

  • 711 Citations
  • 13 h-Index
  • 35 Article
  • 5 Conference contribution
  • 1 Chapter
Filter
Article
2019
1 Citation (Scopus)

Transfer learning for predicting human skin sensitizers

Tung, C. W., Lin, Y. H. & Wang, S. S., Apr 1 2019, In : Archives of Toxicology. 93, 4, p. 931-940 10 p.

Research output: Contribution to journalArticle

Skin
Toxicology
Computational methods
Research Design
Risk assessment
2018

ChemDIS 2: An update of chemical-disease inference system

Tung, C. W. & Wang, S. S., Jan 1 2018, In : Database. 2018, 2018

Research output: Contribution to journalArticle

Open Access
environmental assessment
Information Systems
drugs
Pharmaceutical Preparations
Application programming interfaces (API)
4 Citations (Scopus)

ChemDIS-Mixture: An online tool for analyzing potential interaction effects of chemical mixtures

Tung, C. W., Wang, C. C., Wang, S. S. & Lin, P., Dec 1 2018, In : Scientific Reports. 8, 1, 10047.

Research output: Contribution to journalArticle

Open Access
Online Systems
Proteins
Clinical Studies
3 Citations (Scopus)

Discovery of pyrazolo[4,3-c]quinolines derivatives as potential anti-inflammatory agents through inhibiting of no production

Tseng, C. H., Tung, C. W., Peng, S. I., Chen, Y. L., Tzeng, C. C. & Cheng, C. M., Jan 1 2018, In : Molecules. 23, 5, 1036.

Research output: Contribution to journalArticle

Open Access
Quinolines
quinoline
nitric oxide
Lipopolysaccharides
Nitric Oxide

Human immunodeficiency virus Tat-TIP30 interaction promotes metastasis by enhancing the nuclear translocation of Snail in lung cancer cell lines

Liu, Y. P., Chen, C. H., Yen, C. H., Tung, C. W., Chen, C. J., Chen, Y. M. A. & Huang, M. S., Oct 1 2018, In : Cancer Science. 109, 10, p. 3105-3114 10 p.

Research output: Contribution to journalArticle

tat Gene Products
Lung Neoplasms
HIV
Neoplasm Metastasis
Cell Line
2 Citations (Scopus)

Mechanism-informed read-across assessment of skin sensitizers based on SkinSensDB

Tung, C. W., Wang, C. C. & Wang, S. S., Apr 1 2018, In : Regulatory Toxicology and Pharmacology. 94, p. 276-282 7 p.

Research output: Contribution to journalArticle

Local Lymph Node Assay
Area Under Curve
Skin
Testing
ROC Curve
2017
10 Citations (Scopus)

Determination of cannabinoids in hemp nut products in Taiwan by HPLC-MS/MS coupled with chemometric analysis: quality evaluation and a pilot human study

Chang, C. W., Tung, C. W., Tsai, C. C., Wu, Y. T. & Hsu, M. C., Jun 1 2017, In : Drug Testing and Analysis. 9, 6, p. 888-897 10 p.

Research output: Contribution to journalArticle

Nuts
Dronabinol
Cannabinoids
nut
Cannabis
10 Citations (Scopus)

Discovery of indeno[1,2-c]quinoline derivatives as potent dual antituberculosis and anti-inflammatory agents

Tseng, C. H., Tung, C. W., Wu, C. H., Tzeng, C. C., Chen, Y. H., Hwang, T. L. & Chen, Y. L., Jun 1 2017, In : Molecules. 22, 6, 1001.

Research output: Contribution to journalArticle

Open Access
tuberculosis
quinoline
Leukocyte Elastase
neutrophils
Tuberculosis
3 Citations (Scopus)

Identification of consensus biomarkers for predicting non-genotoxic hepatocarcinogens

Huang, S. H. & Tung, C. W., Jan 24 2017, In : Scientific Reports. 7, 41176.

Research output: Contribution to journalArticle

Open Access
Biomarkers
Toxicogenetics
Decision Trees
Maximum Tolerated Dose
Biological Assay

Identification of informative features for predicting proinflammatory potentials of engine exhausts

Wang, C. C., Lin, Y. C., Lin, Y. C., Jhang, S. R. & Tung, C. W., Aug 18 2017, In : BioMedical Engineering Online. 16, 66.

Research output: Contribution to journalArticle

Open Access
Vehicle Emissions
Exhaust systems (engine)
Computational methods
Alternative fuels
Immune System Diseases
2 Citations (Scopus)

Profiling transcriptomes of human SH-SY5Y neuroblastoma cells exposed to maleic acid

Wang, C. C., Lin, Y. C., Cheng, Y. H. & Tung, C. W., Jan 1 2017, In : PeerJ. 2017, 4, e3175.

Research output: Contribution to journalArticle

Open Access
maleic acid
Gene Expression Profiling
transcriptomics
Neuroblastoma
cells
4 Citations (Scopus)

SkinSensDB: a curated database for skin sensitization assays

Wang, C. C., Lin, Y. C., Wang, S. S., Shih, C., Lin, Y. H. & Tung, C. W., Jan 31 2017, In : Journal of Cheminformatics. 9, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Open Access
sensitization
Assays
Skin
predictions
rodents
2016
3 Citations (Scopus)

Attenuation of antigen-specific T helper 1 immunity by Neolitsea hiiranensis and its derived terpenoids

Cheng, Y. H., Chen, I. S., Lin, Y. C., Tung, C. W., Chang, H. S. & Wang, C. C., Jan 1 2016, In : PeerJ. 2016, 12, e2758.

Research output: Contribution to journalArticle

Open Access
Neolitsea
Viral Tumor Antigens
Terpenes
terpenoids
T-cells
8 Citations (Scopus)

Plasma matrix metalloproteinase 1 improves the detection and survival prediction of esophageal squamous cell carcinoma

Chen, Y. K., Tung, C. W., Lee, J. Y., Hung, Y. C., Lee, C. H., Chou, S. H., Lin, H. S., Wu, M. T. & Wu, I. C., Jul 20 2016, In : Scientific Reports. 6, 30057.

Research output: Contribution to journalArticle

Open Access
Matrix Metalloproteinase 1
Survival
Esophageal Squamous Cell Carcinoma
Proteins
Cell Death
2015
9 Citations (Scopus)

ChemDIS: A chemical-disease inference system based on chemical-protein interactions

Tung, C. W., Jun 15 2015, In : Journal of Cheminformatics. 7, 1, 25.

Research output: Contribution to journalArticle

Open Access
inference
Disease
proteins
Proteins
interaction
34 Citations (Scopus)

Developing a QSAR model for hepatotoxicity screening of the active compounds in traditional Chinese medicines

Huang, S. H., Tung, C. W., Fülöp, F. & Li, J. H., Apr 1 2015, In : Food and Chemical Toxicology. 78, p. 71-77 7 p.

Research output: Contribution to journalArticle

quantitative structure-activity relationships
Quantitative Structure-Activity Relationship
hepatotoxicity
Chinese Traditional Medicine
Medicine
2014
8 Citations (Scopus)

An in silico toxicogenomics approach for inferring potential diseases associated with maleic acid

Lin, Y. C., Wang, C. C. & Tung, C. W., Nov 5 2014, In : Chemico-Biological Interactions. 223, p. 38-44 7 p.

Research output: Contribution to journalArticle

Toxicogenetics
Computer Simulation
Neurology
maleic acid
Food Packaging
36 Citations (Scopus)

A testing strategy to predict risk for drug-induced liver injury in humans using high-content screen assays and the 'rule-of-two' model

Chen, M., Tung, C. W., Shi, Q., Guo, L., Shi, L., Fang, H., Borlak, J. & Tong, W., Jan 1 2014, In : Archives of Toxicology. 88, 7, p. 1439-1449 11 p.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Liver
Assays
Testing
Pharmaceutical Preparations
7 Citations (Scopus)

Interpretable prediction of non-genotoxic hepatocarcinogenic chemicals

Tung, C. W. & Jheng, J. L., Dec 5 2014, In : Neurocomputing. 145, p. 68-74 7 p.

Research output: Contribution to journalArticle

Proteins
Transcriptome
Decision Trees
Quantitative Structure-Activity Relationship
Gene expression
7 Citations (Scopus)

Public databases of plant natural products for computational drug discovery

Tung, C. W., Jan 1 2014, In : Current Computer-Aided Drug Design. 10, 3, p. 191-196 6 p.

Research output: Contribution to journalArticle

Drug Discovery
Biological Products
Databases
Quantitative Structure-Activity Relationship
Ligands
5 Citations (Scopus)

Rule-based knowledge acquisition method for promoter prediction in human and drosophila species

Huang, W. L., Tung, C. W., Liaw, C., Huang, H. L. & Ho, S. Y., Mar 6 2014, In : The Scientific World Journal. 2014, 327306.

Research output: Contribution to journalArticle

Open Access
Knowledge acquisition
Drosophila
DNA sequences
physicochemical property
prediction
10 Citations (Scopus)

TIPdb-3D: The three-dimensional structure database of phytochemicals from Taiwan indigenous plants

Tung, C. W., Lin, Y. C., Chang, H. S., Wang, C. C., Chen, I. S., Jheng, J. L. & Li, J. H., Jan 1 2014, In : Database. 2014

Research output: Contribution to journalArticle

Open Access
Phytochemicals
Taiwan
phytopharmaceuticals
Databases
Chemical Databases
2013
17 Citations (Scopus)

Identification of biomarkers for esophageal squamous cell carcinoma using feature selection and decision tree methods

Tung, C. W., Wu, M. T., Chen, Y. K., Wu, C. C., Chen, W. C., Li, H. P., Chou, S. H., Wu, D. C. & Wu, I. C., Dec 1 2013, In : The Scientific World Journal. 2013, 782031.

Research output: Contribution to journalArticle

Open Access
Decision Trees
Biomarkers
Decision trees
biomarker
Feature extraction
14 Citations (Scopus)

Prediction and Analysis of Antibody Amyloidogenesis from Sequences

Liaw, C., Tung, C. W. & Ho, S. Y., Jan 15 2013, In : PLoS One. 8, 1, e53235.

Research output: Contribution to journalArticle

Open Access
germ cells
antibodies
prediction
Antibodies
Dipeptides
29 Citations (Scopus)

Prediction of pupylation sites using the composition of k-spaced amino acid pairs

Tung, C. W., Nov 7 2013, In : Journal of Theoretical Biology. 336, p. 11-17 7 p.

Research output: Contribution to journalArticle

Amino Acids
Amino acids
Proteins
amino acids
prediction
16 Citations (Scopus)

TIPdb: A database of anticancer, antiplatelet, and antituberculosis phytochemicals from indigenous plants in Taiwan

Lin, Y. C., Wang, C. C., Chen, I. S., Jheng, J. L., Li, J. H. & Tung, C. W., Jun 11 2013, In : The Scientific World Journal. 2013, 736386.

Research output: Contribution to journalArticle

Open Access
Phytochemicals
Taiwan
Databases
Names
Chemical Databases
2012
29 Citations (Scopus)

PupDB: A database of pupylated proteins

Tung, C. W., Mar 16 2012, In : BMC Bioinformatics. 13, 1, 40.

Research output: Contribution to journalArticle

Open Access
Protein Databases
Proteins
Protein
Databases
Ubiquitins
2011
44 Citations (Scopus)

POPISK: T-cell reactivity prediction using support vector machines and string kernels

Tung, C. W., Ziehm, M., Kämper, A., Kohlbacher, O. & Ho, S. Y., Nov 15 2011, In : BMC Bioinformatics. 12, 446.

Research output: Contribution to journalArticle

Open Access
T-cells
Reactivity
Peptides
Support vector machines
Support Vector Machine
2010
8 Citations (Scopus)

Prediction of protein subchloroplast locations using random forests

Tung, C. W., Liaw, C., Ho, S. J. & Ho, S. Y., May 1 2010, In : World Academy of Science, Engineering and Technology. 65, p. 903-907 5 p.

Research output: Contribution to journalArticle

Proteins
Experiments
3 Citations (Scopus)

Sequence-based prediction of gamma-turn types using a physicochemical property-based decision tree method

Liaw, C., Tung, C. W., Ho, S. J. & Ho, S. Y., May 1 2010, In : World Academy of Science, Engineering and Technology. 65, p. 898-902 5 p.

Research output: Contribution to journalArticle

Decision trees
Protein folding
Molecular recognition
Proteins
2009
27 Citations (Scopus)

Predicting protein subnuclear localization using GO-amino-acid composition features

Huang, W. L., Tung, C. W., Huang, H. L. & Ho, S. Y., Nov 1 2009, In : BioSystems. 98, 2, p. 73-79 7 p.

Research output: Contribution to journalArticle

Gene Ontology
Ontology
Amino Acids
Amino acids
Genes
2008
121 Citations (Scopus)

Computational identification of ubiquitylation sites from protein sequences

Tung, C. W. & Ho, S. Y., Jul 15 2008, In : BMC Bioinformatics. 9, 310.

Research output: Contribution to journalArticle

Open Access
Ubiquitination
Protein Sequence
Proteins
Prediction
Support vector machines
92 Citations (Scopus)

ProLoc-GO: Utilizing informative Gene Ontology terms for sequence-based prediction of protein subcellular localization

Huang, W. L., Tung, C. W., Ho, S. W., Hwang, S. F. & Ho, S. Y., Feb 1 2008, In : BMC Bioinformatics. 9, 80.

Research output: Contribution to journalArticle

Open Access
Gene Ontology
Ontology
Genes
Proteins
Protein
2007
72 Citations (Scopus)

POPI: Predicting immunogenicity of MHC class I binding peptides by mining informative physicochemical properties

Tung, C. W. & Ho, S. Y., Apr 15 2007, In : Bioinformatics. 23, 8, p. 942-949 8 p.

Research output: Contribution to journalArticle

Open Access
Major Histocompatibility Complex
Peptides
Mining
Prediction
Immune Response
56 Citations (Scopus)

ProLoc: Prediction of protein subnuclear localization using SVM with automatic selection from physicochemical composition features

Huang, W. L., Tung, C. W., Huang, H. L., Hwang, S. F. & Ho, S. Y., Sep 1 2007, In : BioSystems. 90, 2, p. 573-581 9 p.

Research output: Contribution to journalArticle

Support vector machines
Support Vector Machine
Proteins
Protein
Prediction