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Research Output

  • 403 Citations
  • 12 h-Index
  • 28 Article
  • 3 Comment/debate
2020

CK1δ as a potential therapeutic target to treat bladder cancer

Lin, Y. C., Chen, M. C., Hsieh, T. H., Liou, J. P. & Chen, C. H., Apr 15 2020, In : Aging. 12, 7, p. 5764-5780 17 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Label-free multi-microfluidic immunoassays with liquid crystals on polydimethylsiloxane biosensing chips

Fan, Y. J., Chen, F. L., Liou, J. C., Huang, Y. W., Chen, C. H., Hong, Z. Y., Lin, J. D. & Hsiao, Y. C., Feb 1 2020, In : Polymers. 12, 2, 395.

Research output: Contribution to journalArticle

Open Access

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression

Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., Jan 1 2020, In : European Journal of Medicinal Chemistry. 185, p. 111725 111725.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

Wong, J. Y. Y., Zhang, H., Hsiung, C. A., Shiraishi, K., Yu, K., Matsuo, K., Wong, M. P., Hong, Y. C., Wang, J., Seow, W. J., Wang, Z., Song, M., Kim, H. N., Chang, I. S., Chatterjee, N., Hu, W., Wu, C., Mitsudomi, T., Zheng, W., Kim, J. H. & 166 others, Seow, A., Caporaso, N. E., Shin, M. H., Chung, L. P., An, S. J., Wang, P., Yang, Y., Zheng, H., Yatabe, Y., Zhang, X. C., Kim, Y. T., Cai, Q., Yin, Z., Kim, Y. C., Bassig, B. A., Chang, J., Ho, J., Ji, B. T., Daigo, Y., Ito, H., Momozawa, Y., Ashikawa, K., Kamatani, Y., Honda, T., Hosgood, H. D., Sakamoto, H., Kunitoh, H., Tsuta, K., Watanabe, S. I., Kubo, M., Miyagi, Y., Nakayama, H., Matsumoto, S., Tsuboi, M., Goto, K., Shi, J., Song, L., Hua, X., Takahashi, A., Goto, A., Minamiya, Y., Shimizu, K., Tanaka, K., Wei, F., Matsuda, F., Su, J., Kim, Y. H., Oh, I. J., Song, F., Su, W. C., Chen, Y. M., Chang, G. C., Chen, K. Y., Huang, M. S., Chien, L. H., Xiang, Y. B., Park, J. Y., Kweon, S. S., Chen, C. J., Lee, K. M., Blechter, B., Li, H., Gao, Y. T., Qian, B., Lu, D., Liu, J., Jeon, H. S., Hsiao, C. F., Sung, J. S., Tsai, Y. H., Jung, Y. J., Guo, H., Hu, Z., Wang, W. C., Chung, C. C., Burdett, L., Yeager, M., Hutchinson, A., Berndt, S. I., Wu, W., Pang, H., Li, Y., Choi, J. E., Park, K. H., Sung, S. W., Liu, L., Kang, C. H., Zhu, M., Chen, C. H., Yang, T. Y., Xu, J., Guan, P., Tan, W., Wang, C. L., Hsin, M., Sit, K. Y., Ho, J., Chen, Y., Choi, Y. Y., Hung, J. Y., Kim, J. S., Yoon, H. I., Lin, C. C., Park, I. K., Xu, P., Wang, Y., He, Q., Perng, R. P., Chen, C. Y., Vermeulen, R., Wu, J., Lim, W. Y., Chen, K. C., Li, Y. J., Li, J., Chen, H., Yu, C. J., Jin, L., Chen, T. Y., Jiang, S. S., Liu, J., Yamaji, T., Hicks, B., Wyatt, K., Li, S. A., Dai, J., Ma, H., Jin, G., Song, B., Wang, Z., Cheng, S., Li, X., Ren, Y., Cui, P., Iwasaki, M., Shimazu, T., Tsugane, S., Zhu, J., Yang, K., Jiang, G., Fei, K., Wu, G., Lin, H. C., Chen, H. L., Fang, Y. H., Tsai, F. Y., Hsieh, W. S., Yu, J., Stevens, V. L., Laird-Offringa, I. A., Marconett, C. N., Rieswijk, L., Chao, A., Yang, P. C., Shu, X. O., Wu, T., Wu, Y. L., Lin, D., Chen, K., Zhou, B., Huang, Y. C., Kohno, T., Shen, H., Chanock, S. J., Rothman, N. & Lan, Q., Mar 2020, In : Genomics. 112, 2, p. 1223-1232 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019
Open Access
2 Citations (Scopus)
4 Citations (Scopus)
Open Access
2 Citations (Scopus)
2018

Dual inhibition of PIK3C3 and FGFR as a new therapeutic approach to treat bladder cancer

Chen, C. H., Changou, C. A., Hsieh, T. H., Lee, Y. C., Chu, C. Y., Hsu, K. C., Wang, H. C., Lin, Y. C., Lo, Y. N., Liu, Y. R., Liou, J. P. & Yen, Y., Mar 1 2018, In : Clinical Cancer Research. 24, 5, p. 1176-1189 14 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Rapid on-line microextraction method for the analysis of glyphosate in soy and pepper based on fiber-spray/mass spectrometry

Liou, Y. W., Wang, S. H., Hsu, C. H., Hsu, Y. T., Chen, C. H., Chen, C. C. & Lin, C. H., Jul 2018, In : International Journal of Mass Spectrometry. 430, p. 104-109 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Blockade of dengue virus infection and viral cytotoxicity in neuronal cells in vitro and in vivo by targeting endocytic pathways

Ho, M. R., Tsai, T. T., Chen, C. L., Jhan, M. K., Tsai, C. C., Lee, Y. C., Chen, C. H. & Lin, C. F., Dec 1 2017, In : Scientific Reports. 7, 1, 7023.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2016

Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma

Yang, S. H., Lin, H. Y., Changou, C. A., Chen, C. H., Liu, Y. R., Wang, J., Jiang, X., Luh, F. & Yen, Y., Jan 1 2016, In : Oncotarget. 7, 1, p. 362-373 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
5 Citations (Scopus)
11 Citations (Scopus)
2015
16 Citations (Scopus)
3 Citations (Scopus)

Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo

Huang, H-L., Peng, C-Y., Lai, M-J., Chen, C-H., Lee, H. Y., Wang, J-C., Liou, J. P., Pan, S. L. & Teng, C-M., 2015, In : Oncotarget. 6, 7, p. 4976-4991 16 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The novel ribonucleotide reductase inhibitor COH29 inhibits DNA repair in vitros

Chen, M. C., Zhou, B., Zhang, K., Yuan, Y. C., Un, F., Hu, S., Chou, C. M., Chen, C. H., Wu, J., Wang, Y., Liu, X., Smith, D. L., Li, H., Liu, Z., Warden, C. D., Su, L., Malkas, L. H., Chung, Y. M., Hu, M. C. T. & Yen, Y., Jun 1 2015, In : Molecular Pharmacology. 87, 6, p. 996-1005 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2014

Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo

Chen, C. H., Chen, M. C., Wang, J. C., Tsai, A. C., Chen, C. S., Liou, J. P., Pan, S. L. & Teng, C. M., 2014, In : Clinical Cancer Research. 20, 5, p. 1274-1287 14 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2013

The HDAC inhibitor, MPT0E028, enhances erlotinib-induced cell death in EGFR-TKI-resistant NSCLC cells

Chen, M. C., Chen, C. H., Wang, J. C., Tsai, A. C., Liou, J. P., Pan, S. L. & Teng, C. M., Sep 2013, In : Cell Death and Disease. 4, 9, e810.

Research output: Contribution to journalArticle

50 Citations (Scopus)

TW01001, a novel piperazinedione compound, induces mitotic arrest and autophagy in non-small cell lung cancer A549 cells

Chen, M. C., Chen, C. H., Liu, Y. N., Wang, H. P., Pan, S. L. & Teng, C. M., Aug 19 2013, In : Cancer Letters. 336, 2, p. 370-378 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2012

Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines

Chen, C-H., Liao, C. H., Chang, Y. L., Guh, J. H., Pan, S. L. & Teng, C. M., Feb 1 2012, In : Cancer Letters. 315, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

α-Tomatine-Mediated Anti-Cancer Activity In Vitro and In Vivo through Cell Cycle- and Caspase-Independent Pathways

Chao, M. W., Chen, C-H., Chang, Y. L., Teng, C. M. & Pan, S. L., Sep 6 2012, In : PLoS One. 7, 9, e44093.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2011

Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression

Chen, C-H., Huang, P. H., Chu, P. C., Chen, M. C., Chou, C. C., Wang, D., Kulp, S. K., Teng, C. M., Wang, Q. & Chen, C. S., Mar 25 2011, In : Journal of Biological Chemistry. 286, 12, p. 9968-9976 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Histone deacetylase inhibitors stimulate histone H3 lysine 4 methylation in part via transcriptional repression of histone H3 lysine 4 demethylases

Huang, P. H., Chen, C. H., Chou, C. C., Sargeant, A. M., Kulp, S. K., Teng, C. M., Byrd, J. C. & Chen, C. S., Jan 2011, In : Molecular Pharmacology. 79, 1, p. 197-206 10 p.

Research output: Contribution to journalArticle

82 Citations (Scopus)

Novel mechanism by which histone deacetylase inhibitors facilitate topoisomerase IIα degradation in hepatocellular carcinoma cells

Chen, M. C., Chen, C-H., Chuang, H. C., Kulp, S. K., Teng, C. M. & Chen, C. S., Jan 2011, In : Hepatology. 53, 1, p. 148-159 12 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Thrombin induces expression of twist and cell motility via the hypoxia-inducible factor-1α translational pathway in colorectal cancer cells

Chang, L. H., Chen, C-H., Huang, D. Y., Pai, H. C., Pan, S. L. & Teng, C. M., Apr 2011, In : Journal of Cellular Physiology. 226, 4, p. 1060-1068 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)