Chun-Han Chen

Personal profile

Education

2006-2012 Ph.D., Department of Pharmacy, National Taiwan University
2005-2006 M.S., Department of Pharmacy, National Taiwan University
2000-2005 B.S., Department of Pharmacy, National Taiwan University

Experience

2016.03- Assistant Professor, School of Pharmacy, Taipei Medical University
2016.01-2016.03 Postdoctoral Research Fellow, Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University

Awards

2019 Young Researcher Award, Taipei Medical University

Research Interests

藥理及毒理
藥學

Fingerprint Dive into the research topics where Chun-Han Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

17 Similar Profiles

Histone Deacetylase Inhibitors Medicine & Life Sciences

Autophagy Medicine & Life Sciences

Neoplasms Medicine & Life Sciences

Cell Death Medicine & Life Sciences

Urinary Bladder Neoplasms Medicine & Life Sciences

Apoptosis Medicine & Life Sciences

Cells Chemical Compounds

Histone Deacetylases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

利用轉錄體學與蛋白質體學方法探討膀胱癌對鉑類藥物產生抗藥性之分子機轉研究並開發新的治療策略

Chen, C.

8/1/19 → 7/1/20

Project: A - Government Institution › b - Ministry of Science and Technology

探討CK1 delta在膀胱癌進展的角色，並以其為治療標的之新藥研發。

Chen, C.

8/1/18 → 7/1/19

Project: A - Government Institution › b - Ministry of Science and Technology

PIK3C3抑制劑對於膀胱癌的治療效果與機轉探討

Chen, C.

8/1/17 → 7/31/18

Project: A - Government Institution › b - Ministry of Science and Technology

Targeting Class III Phosphoinositide 3-Kinase (Pi3k) for Anticancer Drug Discovery

Chen, C.

8/1/16 → 7/31/17

Project: A - Government Institution › b - Ministry of Science and Technology

Research Output 2011 2020

362 Citations
11 h-Index
24 Article

1 Citation (Scopus)

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression

Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., Jan 1 2020, In : European Journal of Medicinal Chemistry. 185, p. 111725 111725.

Research output: Contribution to journal › Article

Anilides

HSP90 Heat-Shock Proteins

Histone Deacetylase Inhibitors

Histone Deacetylases

Down-Regulation

MPT0G612, a novel HDAC6 inhibitor, induces apoptosis and suppresses ifn-Γ-induced programmed death-ligand 1 in human colorectal carcinoma cells

Chen, M. C., Lin, Y. C., Liao, Y. H., Liou, J. P. & Chen, C. H., Oct 2019, In : Cancers. 11, 10, 1617.

Research output: Contribution to journal › Article

Open Access

Colorectal Neoplasms

Apoptosis

Ligands

Autophagy

Cell Death

3 Citations (Scopus)

Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents

Liu, Y-M., Chen, C-H., Yeh, T-K. & Liou, J-P., Feb 21 2019, In : Future Medicinal Chemistry.

Research output: Contribution to journal › Article

Urinary Bladder Neoplasms

Antineoplastic Agents

G1 Phase

Ovarian Neoplasms

Solubility

1 Citation (Scopus)

Targeting autophagy by MPT0L145, a highly potent pik3c3 inhibitor, provides synergistic interaction to targeted or chemotherapeutic agents in cancer cells

Chen, C. H., Hsieh, T. H., Lin, Y. C., Liu, Y. R., Liou, J. P. & Yen, Y., Sep 2019, In : Cancers. 11, 9, 1345.

Research output: Contribution to journal › Article

Open Access

Autophagy

Fibroblast Growth Factor Receptors

Neoplasms

Drug Combinations

gemcitabine

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

Wong, J. Y. Y., Zhang, H., Hsiung, C. A., Shiraishi, K., Yu, K., Matsuo, K., Wong, M. P., Hong, Y. C., Wang, J., Seow, W. J., Wang, Z., Song, M., Kim, H. N., Chang, I. S., Chatterjee, N., Hu, W., Wu, C., Mitsudomi, T., Zheng, W., Kim, J. H. & 166 others, Seow, A., Caporaso, N. E., Shin, M. H., Chung, L. P., An, S. J., Wang, P., Yang, Y., Zheng, H., Yatabe, Y., Zhang, X. C., Kim, Y. T., Cai, Q., Yin, Z., Kim, Y. C., Bassig, B. A., Chang, J., Ho, J., Ji, B. T., Daigo, Y., Ito, H., Momozawa, Y., Ashikawa, K., Kamatani, Y., Honda, T., Hosgood, H. D., Sakamoto, H., Kunitoh, H., Tsuta, K., Watanabe, S. I., Kubo, M., Miyagi, Y., Nakayama, H., Matsumoto, S., Tsuboi, M., Goto, K., Shi, J., Song, L., Hua, X., Takahashi, A., Goto, A., Minamiya, Y., Shimizu, K., Tanaka, K., Wei, F., Matsuda, F., Su, J., Kim, Y. H., Oh, I. J., Song, F., Su, W. C., Chen, Y. M., Chang, G. C., Chen, K. Y., Huang, M. S., Chien, L. H., Xiang, Y. B., Park, J. Y., Kweon, S. S., Chen, C. J., Lee, K. M., Blechter, B., Li, H., Gao, Y. T., Qian, B., Lu, D., Liu, J., Jeon, H. S., Hsiao, C. F., Sung, J. S., Tsai, Y. H., Jung, Y. J., Guo, H., Hu, Z., Wang, W. C., Chung, C. C., Burdett, L., Yeager, M., Hutchinson, A., Berndt, S. I., Wu, W., Pang, H., Li, Y., Choi, J. E., Park, K. H., Sung, S. W., Liu, L., Kang, C. H., Zhu, M., Chen, C. H., Yang, T. Y., Xu, J., Guan, P., Tan, W., Wang, C. L., Hsin, M., Sit, K. Y., Ho, J., Chen, Y., Choi, Y. Y., Hung, J. Y., Kim, J. S., Yoon, H. I., Lin, C. C., Park, I. K., Xu, P., Wang, Y., He, Q., Perng, R. P., Chen, C. Y., Vermeulen, R., Wu, J., Lim, W. Y., Chen, K. C., Li, Y. J., Li, J., Chen, H., Yu, C. J., Jin, L., Chen, T. Y., Jiang, S. S., Liu, J., Yamaji, T., Hicks, B., Wyatt, K., Li, S. A., Dai, J., Ma, H., Jin, G., Song, B., Wang, Z., Cheng, S., Li, X., Ren, Y., Cui, P., Iwasaki, M., Shimazu, T., Tsugane, S., Zhu, J., Yang, K., Jiang, G., Fei, K., Wu, G., Lin, H. C., Chen, H. L., Fang, Y. H., Tsai, F. Y., Hsieh, W. S., Yu, J., Stevens, V. L., Laird-Offringa, I. A., Marconett, C. N., Rieswijk, L., Chao, A., Yang, P. C., Shu, X. O., Wu, T., Wu, Y. L., Lin, D., Chen, K., Zhou, B., Huang, Y. C., Kohno, T., Shen, H., Chanock, S. J., Rothman, N. & Lan, Q., Jan 1 2019, In : Genomics.

Research output: Contribution to journal › Article

Mendelian Randomization Analysis

Genome-Wide Association Study

Tuberculosis

Smoking

Infection