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Chun-Han Chen

Assistant Professor

 https://orcid.org/0000-0001-6328-466X
  • 437 Citations
  • 13 h-Index
20112020

Research output per year

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Personal profile

Education

  • 2006-2012 Ph.D., Department of Pharmacy, National Taiwan University
  • 2005-2006 M.S., Department of Pharmacy, National Taiwan University
  • 2000-2005 B.S., Department of Pharmacy, National Taiwan University

Experience

  • 2016.03- Assistant Professor, School of Pharmacy, Taipei Medical University 
  • 2016.01-2016.03 Postdoctoral Research Fellow, Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
  • 2013.07-2014.02 Postdoctoral Research Scholar, Academia Sinica
  • 2012.02-2013.06 Postdoctoral Research Fellow, National Taiwan University

Awards

  •  2019 Young Researcher Award, Taipei Medical University

Research Interests

  • 藥理及毒理
  • 藥學

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Projects

利用轉錄體學與蛋白質體學方法探討膀胱癌對鉑類藥物產生抗藥性之分子機轉研究並開發新的治療策略(第二年)

Chen, C.

8/1/20 → 7/1/21

Project: A - Government Institution › b - Ministry of Science and Technology

Using Transcriptomic and Proteomic Approaches to Investigate the Molecular Mechanisms of Platinum-Resistance in Bladder Cancer and Develop New Therapeutic Strategies

Chen, C.

8/1/19 → 7/31/20

Project: A - Government Institution › b - Ministry of Science and Technology

Investigating the Role of Ck1 Delta in Tumor Progression, and as a Therapeutic Target for New Drug Discovery in Bladder Cancer.

Chen, C.

8/1/18 → 7/1/19

Project: A - Government Institution › b - Ministry of Science and Technology

Antitumor Activity and Pharmacological Mechanisms of Pik3c3 Inhibitor in Bladder Cancer Cells

Chen, C.

8/1/17 → 7/31/18

Project: A - Government Institution › b - Ministry of Science and Technology

Targeting Class III Phosphoinositide 3-Kinase (Pi3k) for Anticancer Drug Discovery

Chen, C.

8/1/16 → 7/31/17

Project: A - Government Institution › b - Ministry of Science and Technology

Research Output

  • 437 Citations
  • 13 h-Index
  • 28 Article
  • 3 Comment/debate

CK1δ as a potential therapeutic target to treat bladder cancer

Lin, Y. C., Chen, M. C., Hsieh, T. H., Liou, J. P. & Chen, C. H., Apr 15 2020, In : Aging. 12, 7, p. 5764-5780 17 p.

Research output: Contribution to journal › Article

    • Corrigendum to “Design, synthesis, and evaluation of N-phenyl-4-(2-phenylsulfonamido)-benzamides as microtubule-targeting agents in drug-resistant cancer cells, displaying HDAC inhibitory response” [Eur J Med Chem. 192 2020 112158] (European Journal of Medicinal Chemistry (2020) 192, (S0223523420301252), (10.1016/j.ejmech.2020.112158))

    Wu, W. C., Liu, Y. M., Lin, M. H., Liao, Y. H., Lai, M. J., Chuang, H. Y., Hung, T. Y., Chen, C. H. & Liou, J. P., Jun 15 2020, In : European Journal of Medicinal Chemistry. 196, 112329.

    Research output: Contribution to journal › Comment/debate

    Open Access

    • Corrigendum to“Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo”[Eur. J. Med. Chem. 190 (2020 Mar 15) 112086] (European Journal of Medicinal Chemistry (2020) 190, (S0223523420300532), (10.1016/j.ejmech.2020.112086))

    Ojha, R., Nepali, K., Chen, C. H., Chuang, K. H., Wu, T. Y., Lin, T. E., Hsu, K. C., Chao, M. W., Lai, M. J., Lin, M. H., Huang, H. L., Chang, C. D., Pan, S. L., Chen, M. C. & Liou, J. P., Sep 1 2020, In : European Journal of Medicinal Chemistry. 201, 112404.

    Research output: Contribution to journal › Comment/debate

    • Corrigendum to “N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression”[Eur. J. Med. Chem. 2020 Jan 1;185:111725] (European Journal of Medicinal Chemistry (2020) 185, (S0223523419308773), (10.1016/j.ejmech.2019.111725))

    Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., Aug 1 2020, In : European Journal of Medicinal Chemistry. 199, 112406.

    Research output: Contribution to journal › Comment/debate

    Open Access

    • Design, synthesis, and evaluation of N-phenyl-4-(2-phenylsulfonamido)-benzamides as microtubule-targeting agents in drug-resistant cancer cells, displaying HDAC inhibitory response

    Wu, W. C., Liu, Y. M., Lin, M. H., Liao, Y. H., Lai, M. J., Chuang, H. Y., Hung, T. Y., Chen, C. H. & Liou, J. P., Apr 15 2020, In : European Journal of Medicinal Chemistry. 192, p. 112158 112158.

    Research output: Contribution to journal › Article

    • 1 Citation (Scopus)