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Research Output 2006 2019

  • 357 Citations
  • 10 h-Index
  • 26 Article
2019
2 Citations (Scopus)
Open Access
CCAAT-Enhancer-Binding Protein-delta
Platelet-Derived Growth Factor
Glioma
Stem Cells
Interleukin-1
3 Citations (Scopus)
temozolomide
Dehydroepiandrosterone
Glioblastoma
Acetylation
Phosphorylation
Embryonal Carcinoma Stem Cells
Neural Stem Cells
Zinc Fingers
Transcription
Zinc
2018
4 Citations (Scopus)

Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation

Wang, S. M., Lim, S. W., Wang, Y. H., Lin, H. Y., Lai, M. D., Ko, C. Y. & Wang, J. M., Jun 1 2018, In : Redox Biology. 16, p. 104-112 9 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Oxidative stress
Reactive Oxygen Species
Astrocytes
Oxidative Stress
5 Citations (Scopus)

Highly sensitive/selective 3D nanostructured immunoparticle-based interface on a multichannel sensor array for detecting amyloid-beta in Alzheimer's disease

Liu, T. C., Lee, Y. C., Ko, C. Y., Liu, R. S., Ke, C. C., Lo, Y. C., Hong, P. S., Chu, C. Y., Chang, C. W., Wu, P. W., Chen, Y. Y. & Chen, S. Y., Jan 1 2018, In : Theranostics. 8, 15, p. 4210-4225 16 p.

Research output: Contribution to journalArticle

Amyloid
Fibroins
Alzheimer Disease
Silk
Peptides
6 Citations (Scopus)
Ubiquitination
Glioma
Glioblastoma
Stem Cells
temozolomide
2017
2 Citations (Scopus)

Bortezomib-induced miRNAs direct epigenetic silencing of locus genes and trigger apoptosis in leukemia

Chu, Y. Y., Ko, C. Y., Wang, S. M., Lin, P. I., Wang, H. Y., Lin, W. C., Wu, D. Y., Wang, L. H. & Wang, J. M., Nov 9 2017, In : Cell death & disease. 8, 11, p. e3167

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Gene Silencing
Yin-Yang
MicroRNAs
Epigenomics
10 Citations (Scopus)

Dengue virus infection increases microglial cell migration

Jhan, M. K., Tsai, T. T., Chen, C. L., Tsai, C. C., Cheng, Y. L., Lee, Y. C., Ko, C. Y., Lin, Y. S., Chang, C. P., Lin, L. T. & Lin, C. F., Jan 1 2017, In : Scientific Reports. 7, 1, 91.

Research output: Contribution to journalArticle

Dengue Virus
Virus Diseases
Cell Movement
Clathrin
Viral RNA
6 Citations (Scopus)

Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells

Huang, T. C., Lee, P. T., Wu, M. H., Huang, C. C., Ko, C. Y., Lee, Y. C., Lin, D. Y., Cheng, Y. W. & Lee, K. H., Aug 1 2017, In : PLoS One. 12, 8, e0181034.

Research output: Contribution to journalArticle

RNA Isoforms
colorectal neoplasms
Colorectal Neoplasms
Catenins
Cells
9 Citations (Scopus)

Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase

Chang, K. Y., Hsu, T. I., Hsu, C. C., Tsai, S. Y., Liu, J. J., Chou, S. W., Liu, M. S., Liou, J. P., Ko, C. Y., Chen, K. Y., Hung, J. J., Chang, W. C., Chuang, C. K., Kao, T. J. & Chuang, J. Y., Oct 1 2017, In : Redox Biology. 13, p. 655-664 10 p.

Research output: Contribution to journalArticle

temozolomide
Methyltransferases
Glioblastoma
DNA
Proteins
temozolomide
Dehydroepiandrosterone
Glioma
Cytochrome P-450 Enzyme System
Up-Regulation
2016
7 Citations (Scopus)

Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury

Wang, S. M., Hsu, J. Y. C., Ko, C. Y., Chiu, N. E., Kan, W. M., Lai, M. D. & Wang, J. M., Nov 1 2016, In : Molecular Neurobiology. 53, 9, p. 5912-5927

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Spinal Cord Injuries
Neuroglia
Astrocytes
Cicatrix
10 Citations (Scopus)

Astrocytic CCAAT/Enhancer Binding Protein δ Regulates Neuronal Viability and Spatial Learning Ability via miR-135a

Chu, Y. Y., Ko, C. Y., Wang, W. J., Wang, S. M., Gean, P. W., Kuo, Y. M. & Wang, J. M., 2016, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Proteins
Astrocytes
Alzheimer Disease
Apoptosis
Thrombospondin 1
5 Citations (Scopus)

IL-18-induced interaction between IMP3 and HuR contributes to COX-2 mRNA stabilization in acute myeloid leukemia

Ko, C. Y., Wang, W. L., Li, C. F., Jeng, Y. M., Chu, Y. Y., Wang, H. Y., Tseng, J. T. & Wang, J. M., Jan 1 2016, In : Journal of Leukocyte Biology. 99, 1, p. 131-141 11 p.

Research output: Contribution to journalArticle

Interleukin-18
Cyclooxygenase 2
Acute Myeloid Leukemia
Messenger RNA
Drug Resistance
8 Citations (Scopus)

Suberoylanilide hydroxamic acid represses glioma stem-like cells

Hsu, C. C., Chang, W-C., Hsu, T-I., Liu, J. J., Yeh, S. H., Wang, J-Y., Liou, J-P., Ko, C-Y., Chang, K. Y. & Chuang, J-Y., Nov 18 2016, In : Journal of Biomedical Science. 23, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Glioma
Stem Cells
Glioblastoma
Cells
Histone Deacetylases
2015
24 Citations (Scopus)

Biological roles of CCAAT/enhancer-binding protein delta during inflammation

Ko, C. Y., Chang, W. C. & Wang, J. M., Jan 16 2015, In : Journal of Biomedical Science. 22, 1, 6.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Inflammation
Genes
CCAAT-Enhancer-Binding Proteins
Biological Phenomena
7 Citations (Scopus)

HMDB and 5-AzadC combination reverses tumor suppressor CCAAT/enhancer-binding protein delta to strengthen the death of liver cancer cells

Li, C. F., Tsai, H. H., Ko, C. Y., Pan, Y. C., Yen, C. J., Lai, H. Y., Yuh, C. H., Wu, W. C. & Wang, J. M., Nov 1 2015, In : Molecular Cancer Therapeutics. 14, 11, p. 2623-2633 11 p.

Research output: Contribution to journalArticle

decitabine
CCAAT-Enhancer-Binding Protein-delta
Tumor Suppressor Proteins
Liver Neoplasms
Epigenomics
13 Citations (Scopus)

The CCAAT/enhancer-binding protein delta/miR135a/thrombospondin 1 axis mediates PGE2-induced angiogenesis in Alzheimer's disease

Ko, C. Y., Chu, Y. Y., Narumiya, S., Chi, J. Y., Furuyashiki, T., Aoki, T., Wang, S. M., Chang, W. C. & Wang, J. M., Mar 1 2015, In : Neurobiology of Aging. 36, 3, p. 1356-1368 13 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Thrombospondin 1
Dinoprostone
Alzheimer Disease
Astrocytes
2014
17 Citations (Scopus)

Glycogen synthase kinase-3β-mediated CCAAT/enhancer-binding protein delta phosphorylation in astrocytes promotes migration and activation of microglia/macrophages

Ko, C. Y., Wang, W. L., Wang, S. M., Chu, Y. Y., Chang, W. C. & Wang, J. M., Jan 2014, In : Neurobiology of Aging. 35, 1, p. 24-34 11 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Glycogen Synthase Kinase 3
Macrophage Activation
Microglia
Astrocytes
24 Citations (Scopus)

Increase of Zinc Finger Protein 179 in Response to CCAAT/Enhancer Binding Protein Delta Conferring an Antiapoptotic Effect in Astrocytes of Alzheimer’s Disease

Wang, S. M., Lee, Y. C., Ko, C. Y., Lai, M. D., Lin, D. Y., Pao, P. C., Chi, J. Y., Hsiao, Y. W., Liu, T. L. & Wang, J. M., 2014, In : Molecular Neurobiology. 51, 1, p. 370-382 13 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Zinc Fingers
Astrocytes
Alzheimer Disease
Proteins
9 Citations (Scopus)

The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer

Chuang, C. H., Wang, W. J., Li, C. F., Ko, C-Y., Chou, Y. H., Chuu, C. P., Cheng, T. L. & Wang, J. M., 2014, In : Cell Death and Disease. 5, 5, e1220.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Prodrugs
Caspases
Prostatic Neoplasms
Caspase 8
2012
34 Citations (Scopus)

CCAAT/enhancer binding protein delta (CEBPD) elevating PTX3 expression inhibits macrophage-mediated phagocytosis of dying neuron cells

Ko, C. Y., Chang, L. H., Lee, Y. C., Sterneck, E., Cheng, C. P., Chen, S. H., Huang, A. M., Tseng, J. T. & Wang, J. M., Feb 2012, In : Neurobiology of Aging. 33, 2

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Phagocytosis
Macrophages
Neurons
Alzheimer Disease
2010
22 Citations (Scopus)

CEBPD reverses RB/E2F1-mediated gene repression and participates in HMDB-induced apoptosis of cancer cells

Pan, Y. C., Li, C. F., Ko, C. Y., Pan, M. H., Chen, P. J., Tseng, J. T., Wu, W. C., Chang, W. C., Huang, A. M., Sterneck, E. & Wang, J. M., Dec 1 2010, In : Clinical Cancer Research. 16, 23, p. 5770-5780 11 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Retinoblastoma
Apoptosis
Genes
Neoplasms
2008
55 Citations (Scopus)

Epigenetic silencing of CCAAT/enhancer-binding protein δ activity by YY1/polycomb group/DNA methyltransferase complex

Ko, C. Y., Hsu, H. C., Shen, M. R., Chang, W. C. & Wang, J. M., Nov 7 2008, In : Journal of Biological Chemistry. 283, 45, p. 30919-30932 14 p.

Research output: Contribution to journalArticle

Yin-Yang
CCAAT-Enhancer-Binding Proteins
Methyltransferases
Epigenomics
Gene expression
31 Citations (Scopus)

HDAC1/HDAC3 modulates PPARG2 transcription through the sumoylated CEBPD in hepatic lipogenesis

Lai, P. H., Wang, W. L., Ko, C. Y., Lee, Y. C., Yang, W. M., Shen, T. W., Chang, W. C. & Wang, J. M., Oct 2008, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1783, 10, p. 1803-1814 12 p.

Research output: Contribution to journalArticle

Lipogenesis
Hep G2 Cells
Sumoylation
Liver
CCAAT-Enhancer-Binding Proteins
2006
44 Citations (Scopus)

Functional role of NF-IL6β and its sumoylation and acetylation modifications in promoter activation of cyclooxygenase 2 gene

Wang, J. M., Ko, C. Y., Chen, L. C., Wang, W. L. & Chang, W. C., Jan 2006, In : Nucleic Acids Research. 34, 1, p. 217-231 15 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-beta
Sumoylation
Cyclooxygenase 2
Acetylation
Epidermal Growth Factor