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Research Output 1999 2019

2014
21 Citations (Scopus)

Helicobacter pylori infection activates Src homology-2 domain-containing phosphatase 2 to suppress IFN-γ signaling

Wang, Y-C., Chen, C-L., Sheu, B-S., Yang, Y-J., Tseng, P-C., Hsieh, C-Y. & Lin, C. F., Oct 15 2014, In : Journal of Immunology. 193, 8, p. 4149-4158 10 p.

Research output: Contribution to journalArticle

SH2 Domain-Containing Protein Tyrosine Phosphatases
Helicobacter Infections
Helicobacter pylori
Cytotoxins
Stomach
7 Citations (Scopus)

Inhibiting glucosylceramide synthase facilitates the radiosensitizing effects of vinorelbine in lung adenocarcinoma cells

Chiu, W. H., Chen, H. H. W., Chang, J. Y., Luo, S. J., Li, C. L., Chen, C. L., Su, W. C. & Lin, C. F., Jul 28 2014, In : Cancer Letters. 349, 2, p. 144-151 8 p.

Research output: Contribution to journalArticle

ceramide glucosyltransferase
Radiation-Sensitizing Agents
Chemoradiotherapy
Apoptosis
Non-Small Cell Lung Carcinoma

Lessons learned from dengue: Focus on Taiwan

Ho, T. S., Lin, C. F., Liu, C. C., Yeh, T. M., Anderson, R. & Lin, Y. S., Feb 1 2014, Clinical Insights: Dengue: Transmission, Diagnosis & Surveillance. Future Medicine Ltd., p. 49-64 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dengue Vaccines
Dengue
Taiwan
Epidemiology
Viruses
13 Citations (Scopus)

Macrophage migration inhibitory factor triggers chemotaxis of CD74+CXCR2+NKT cells in chemically induced IFN-γ-Mediated skin inflammation

Hsieh, C-Y., Chen, C-L., Lin, Y-S., Yeh, T-M., Tsai, T-T., Hong, M-Y. & Lin, C. F., Oct 1 2014, In : Journal of Immunology. 193, 7, p. 3693-3703 11 p.

Research output: Contribution to journalArticle

Macrophage Migration-Inhibitory Factors
Natural Killer T-Cells
Chemotaxis
Inflammation
Skin
26 Citations (Scopus)

Panton-valentine leukocidin facilitates the escape of staphylococcus aureus from human keratinocyte endosomes and induces apoptosis

Chi, C. Y., Lin, C. C., Liao, I. C., Yao, Y. C., Shen, F. C., Liu, C. C. & Lin, C. F., Jan 15 2014, In : Journal of Infectious Diseases. 209, 2, p. 224-235 12 p.

Research output: Contribution to journalArticle

Endosomes
Keratinocytes
Methicillin-Resistant Staphylococcus aureus
Staphylococcus aureus
Apoptosis
27 Citations (Scopus)

Protection against dengue virus infection in mice by administration of antibodies against modified nonstructural protein 1

Wan, S. W., Lu, Y. T., Huang, C. H., Lin, C. F., Anderson, R., Liu, H. S., Yeh, T. M., Yen, Y. T., Wu-Hsieh, B. A. & Lin, Y. S., Mar 21 2014, In : PLoS One. 9, 3, e92495.

Research output: Contribution to journalArticle

Dengue virus
Dengue Virus
Virus Diseases
Viruses
antibodies
17 Citations (Scopus)
Glycogen Synthase Kinase 3
HL-60 Cells
Tretinoin
Granulocytes
Reactive Oxygen Species
22 Citations (Scopus)

Rosiglitazone regulates anti-inflammation and growth inhibition via PTEN

Lin, C. F., Young, K. C., Bai, C. H., Yu, B. C., Ma, C. T., Chien, Y. C., Chiang, C. L., Liao, C. S., Lai, H. W. & Tsao, C. W., 2014, In : BioMed Research International. 2014, 787924.

Research output: Contribution to journalArticle

rosiglitazone
Inflammation
Reactive Oxygen Species
Growth
PPAR gamma
2013
8 Citations (Scopus)

A modified fixed staining method for the simultaneous measurement of reactive oxygen species and oxidative responses

Shen, W-J., Hsieh, C-Y., Chen, C-L., Yang, K-C., Ma, C-T., Choi, P-C. & Lin, C. F., Jan 4 2013, In : Biochemical and Biophysical Research Communications. 430, 1, p. 442-447 6 p.

Research output: Contribution to journalArticle

Reactive Oxygen Species
Staining and Labeling
Phosphorylation
Acetic Acid
Methanol
30 Citations (Scopus)

An emerging role for the anti-inflammatory cytokine interleukin-10 in dengue virus infection

Tsai, T-T., Chuang, Y-J., Lin, Y-S., Wan, S-W., Chen, C-L. & Lin, C. F., 2013, In : Journal of Biomedical Science. 20, 1, 40.

Research output: Contribution to journalArticle

Dengue Virus
Virus Diseases
Viruses
Interleukin-10
Severe Dengue
22 Citations (Scopus)

Anti-dengue virus nonstructural protein 1 antibodies cause NO-mediated endothelial cell apoptosis via ceramide-regulated glycogen synthase kinase-3β and NF-κB activation

Chen, C-L., Lin, C. F., Wan, S-W., Wei, L-S., Chen, M-C., Yeh, T-M., Liu, H-S., Anderson, R. & Lin, Y-S., Aug 15 2013, In : Journal of Immunology. 191, 4, p. 1744-1752 9 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Dengue Virus
Ceramides
Endothelial Cells
Apoptosis
42 Citations (Scopus)

Autoimmunity in dengue pathogenesis

Wan, S. W., Lin, C. F., Yeh, T. M., Liu, C. C., Liu, H. S., Wang, S., Ling, P., Anderson, R., Lei, H. Y. & Lin, Y. S., Jan 2013, In : Journal of the Formosan Medical Association = Taiwan yi zhi. 112, 1, p. 3-11 9 p.

Research output: Contribution to journalArticle

Dengue Virus
Dengue
Severe Dengue
Autoimmunity
Virus Diseases
10 Citations (Scopus)

Blockade of reactive oxygen species and Akt activation is critical for anti-inflammation and growth inhibition of metformin in phosphatase and tensin homolog-deficient RAW264.7 cells

Lin, C. F., Young, K. C., Bai, C. H., Yu, B. C., Ma, C. T., Chien, Y. C., Su, H. C., Wang, H. Y., Liao, C. S., Lai, H. W. & Tsao, C. W., Dec 2013, In : Immunopharmacology and Immunotoxicology. 35, 6, p. 669-677 9 p.

Research output: Contribution to journalArticle

Metformin
Cell growth
Phosphoric Monoester Hydrolases
Reactive Oxygen Species
Chemical activation
48 Citations (Scopus)

Current progress in dengue vaccines

Wan, S. W., Lin, C. F., Wang, S., Chen, Y. H., Yeh, T. M., Liu, H. S., Anderson, R. & Lin, Y. S., 2013, In : Journal of Biomedical Science. 20, 1, 37.

Research output: Contribution to journalArticle

Dengue Vaccines
Viruses
Severe Dengue
Attenuated Vaccines
Dengue
7 Citations (Scopus)

Glycogen synthase kinase-3β inactivation is an intracellular marker and regulator for endotoxemic neutrophilia

Yang, T-T., Chen, C-L., Lin, W-C., Lin, Y-S., Tseng, P-C., Hsieh, C-Y., Chen, Y-H., Huang, W-C., Tsai, C-C., Wang, C-Y., Shieh, C-C. & Lin, C. F., Feb 2013, In : Journal of Molecular Medicine. 91, 2, p. 207-217 11 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Myeloid Cell Leukemia Sequence 1 Protein
Apoptosis
Neutrophils
p38 Mitogen-Activated Protein Kinases
30 Citations (Scopus)

Macrophage-mediated inflammatory disorders

Jou, I. M., Lin, C. F., Tsai, K. J. & Wei, S. J., 2013, In : Mediators of Inflammation. 2013, 316482.

Research output: Contribution to journalArticle

Streptococcal Infections
Macrophage Activation
Peripheral Nervous System Diseases
Chemokines
Respiratory Tract Infections
24 Citations (Scopus)

Plasma kallistatin levels in patients with severe community-acquired pneumonia

Lin, W. C., Lu, S. L., Lin, C. F., Chen, C. W., Chao, L., Chao, J. & Lin, Y. S., Feb 8 2013, In : Critical Care. 17, 1, R27.

Research output: Contribution to journalArticle

Pneumonia
Intensive Care Units
Protein C
Interleukin-1
Thrombin
21 Citations (Scopus)

Regulatory role of GSK-3 β on NF-B, nitric oxide, and TNF-α in group A streptococcal infection

Chang, Y-T., Chen, C-L., Lin, C. F., Lu, S-L., Cheng, M-H., Kuo, C-F. & Lin, Y-S., 2013, In : Mediators of Inflammation. 2013, 720689.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Streptococcal Infections
Nitric Oxide
Streptococcus
Nitric Oxide Synthase Type II
1 Citation (Scopus)

Uropathogenic Escherichia coli causes cortical tubular necrotic cell death and the release of macrophage migration inhibitory factor

Hong, M-Y., Tseng, C-C., Chuang, C-C., Chen, C-L., Lin, Y-H., Hsieh, C-Y., Chang, Y-T., Hsing, C. H., Chang, K-Y. & Lin, C. F., Mar 2013, In : Cytokine. 61, 3, p. 945-952 8 p.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Macrophage Migration-Inhibitory Factors
Cell death
Escherichia coli
Cell Death
2012
26 Citations (Scopus)

Albumin prevents reactive oxygen species-induced mitochondrial damage, autophagy, and apoptosis during serum starvation

Liu, S-Y., Chen, C-L., Yang, T-T., Huang, W-C., Hsieh, C-Y., Shen, W-J., Tsai, T-T., Shieh, C-C. & Lin, C. F., Nov 2012, In : Apoptosis. 17, 11, p. 1156-1169 14 p.

Research output: Contribution to journalArticle

Autophagy
Starvation
NADPH Oxidase
Albumins
Reactive Oxygen Species
27 Citations (Scopus)

Anesthetic propofol causes glycogen synthase kinase-3β-regulated lysosomal/mitochondrial apoptosis in macrophages

Hsing, C. H., Chen, Y. H., Chen, C. L., Huang, W. C., Lin, M. C., Tseng, P. C., Wang, C. Y., Tsai, C. C., Choi, P. C. & Lin, C. F., Apr 2012, In : Anesthesiology. 116, 4, p. 868-881 14 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Propofol
Anesthetics
Macrophages
Apoptosis
10 Citations (Scopus)

Anesthetic propofol overdose causes endothelial cytotoxicity in vitro and endothelial barrier dysfunction in vivo

Lin, M-C., Chen, C-L., Yang, T-T., Choi, P-C., Hsing, C-H. & Lin, C-F., Dec 1 2012, In : Toxicology and Applied Pharmacology. 265, 2, p. 253-262 10 p.

Research output: Contribution to journalArticle

Propofol
Cytotoxicity
Anesthetics
Endothelial cells
Glycogen Synthase Kinase 3
43 Citations (Scopus)

Annexin A2 silencing induces G2 arrest of non-small cell lung cancer cells through p53-dependent and -independent mechanisms

Wang, C. Y., Chen, C. L., Tseng, Y. L., Fang, Y. T., Lin, Y. S., Su, W. C., Chen, C. C., Chang, K. C., Wang, Y. C. & Lin, C. F., Sep 21 2012, In : Journal of Biological Chemistry. 287, 39, p. 32512-32524 13 p.

Research output: Contribution to journalArticle

Annexin A2
Annexins
Non-Small Cell Lung Carcinoma
Cells
Cell proliferation
53 Citations (Scopus)

Endothelial cell surface expression of protein disulfide isomerase activates β1 and β3 integrins and facilitates dengue virus infection

Wan, S. W., Lin, C. F., Lu, Y. T., Lei, H. Y., Anderson, R. & Lin, Y. S., May 2012, In : Journal of Cellular Biochemistry. 113, 5, p. 1681-1691 11 p.

Research output: Contribution to journalArticle

Protein Disulfide-Isomerases
Dengue Virus
Endothelial cells
Virus Diseases
Viruses
7 Citations (Scopus)

Glycogen synthase kinase-3β is critical for Interferon-α-induced serotonin uptake in human Jurkat T cells

Tsao, C. W., Lin, C. F., Wu, H. T., Ma, C. T., Huang, W. C., Hsieh, C. Y., Choi, P. C. & Young, K. C., Jun 2012, In : Journal of Cellular Physiology. 227, 6, p. 2556-2566 11 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Jurkat Cells
T-cells
Interferons
Serotonin
22 Citations (Scopus)

Glycogen synthase kinase-3β regulates anti-inflammatory property of fluoxetine

Su, H. C., Ma, C. T., Yu, B. C., Chien, Y. C., Tsai, C. C., Huang, W. C., Lin, C. F., Chuang, Y. H., Young, K. C., Wang, J. N. & Tsao, C. W., Oct 2012, In : International Immunopharmacology. 14, 2, p. 150-156 7 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Fluoxetine
Anti-Inflammatory Agents
Glycogen Synthase Kinases
Lipopolysaccharides
2412 Citations (Scopus)

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L., Alegre-Abarrategui, J. & 1,249 others, Aleo, M. F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H., Cho, D. H., Choi, A. M. K., Choi, D., Choi, K. S., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M., Cullen, J. J., Czaja, M. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., De Groot, J. F., De Haan, C. A. M., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Deng, Y. Z., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S. D., Devenish, R. J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S. P., Ding, W. X., Distelhorst, C. W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F. C., Dosenko, V., Dowling, J. J., Doxsey, S., Dreux, M., Drew, M. E., Duan, Q., Duchosal, M. A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Eissa, N. T., Ekmekcioglu, S., El-Deiry, W. S., Elazar, Z., Elgendy, M., Ellerby, L. M., Er Eng, K., Engelbrecht, A. M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E. L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q. W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farré, J. C., Faure, M., Fechheimer, M., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Fiorito, F., Fisher, E. A., Fisher, P. B., Flajolet, M., Florez-McClure, M. L., Florio, S., Fon, E. A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D. H., Fox, H. S., Franco, R., Frankel, L. B., Fransen, M., Fuentes, J. M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R. H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F. B., Gao, G. F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Gautel, M., Gawriluk, T. R., Gegg, M. E., Geng, J., Germain, M., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghosh, P., Giammarioli, A. M., Giatromanolaki, A. N., Gibson, S. B., Gilkerson, R. W., Ginger, M. L., Ginsberg, H. N., Golab, J., Goligorsky, M. S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C. D., Gonzalez, R., González-Estévez, C., González-Polo, R. A., Gonzalez-Rey, E., Gorbunov, N. V., Gorski, S., Goruppi, S., Gottlieb, R. A., Gozuacik, D., Granato, G. E., Grant, G. D., Green, K. N., Gregorc, A., Gros, F., Grose, C., Grunt, T. W., Gual, P., Guan, J. L., Guan, K. L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Gustafsson, A. B., Halayko, A. J., Hale, A. N., Halonen, S. K., Hamasaki, M., Han, F., Han, T., Hancock, M. K., Hansen, M., Harada, H., Harada, M., Hardt, S. E., Harper, J. W., Harris, A. L., Harris, J., Harris, S. D., Hashimoto, M., Haspel, J. A., Hayashi, S. I., Hazelhurst, L. A., He, C., He, Y. W., Hébert, M. J., Heidenreich, K. A., Helfrich, M. H., Helgason, G. V., Henske, E. P., Herman, B., Herman, P. K., Hetz, C., Hilfiker, S., Hill, J. A., Hocking, L. J., Hofman, P., Hofmann, T. G., Höhfeld, J., Holyoake, T. L., Hong, M. H., Hood, D. A., Hotamisligil, G. S., Houwerzijl, E. J., Høyer-Hansen, M., Hu, B., Hu, C. A. A., Hu, H. M., Hua, Y., Huang, C., Huang, J., Huang, S., Huang, W. P., Huber, T. B., Huh, W. K., Hung, T. H., Hupp, T. R., Hur, G. M., Hurley, J. B., Hussain, S. N. A., Hussey, P. J., Hwang, J. J., Hwang, S., Ichihara, A., Ilkhanizadeh, S., Inoki, K., Into, T., Iovane, V., Iovanna, J. L., Ip, N. Y., Isaka, Y., Ishida, H., Isidoro, C., Isobe, K. I., Iwasaki, A., Izquierdo, M., Izumi, Y., Jaakkola, P. M., Jäättelä, M., Jackson, G. R., Jackson, W. T., Janji, B., Jendrach, M., Jeon, J. H., Jeung, E. B., Jiang, H., Jiang, H., Jiang, J. X., Jiang, M., Jiang, Q., Jiang, X., Jiménez, A., Jin, M., Jin, S., Joe, C. O., Johansen, T., Johnson, D. E., Johnson, G. V. W., Jones, N. L., Joseph, B., Joseph, S. K., Joubert, A. M., Juhász, G., Juillerat-Jeanneret, L., Jung, C. H., Jung, Y. K., Kaarniranta, K., Kaasik, A., Kabuta, T., Kadowaki, M., Kagedal, K., Kamada, Y., Kaminskyy, V. O., Kampinga, H. H., Kanamori, H., Kang, C., Kang, K. B., Il Kang, K., Kang, R., Kang, Y. A., Kanki, T., Kanneganti, T. D., Kanno, H., Kanthasamy, A. G., Kanthasamy, A., Karantza, V., Kaushal, G. P., Kaushik, S., Kawazoe, Y., Ke, P. Y., Kehrl, J. H., Kelekar, A., Kerkhoff, C., Kessel, D. H., Khalil, H., Kiel, J. A. K. W., Kiger, A. A., Kihara, A., Kim, D. R., Kim, D. H., Kim, D. H., Kim, E. K., Kim, H. R., Kim, J. S., Kim, J. H., Kim, J. C., Kim, J. K., Kim, P. K., Kim, S. W., Kim, Y. S., Kim, Y., Kimchi, A., Kimmelman, A. C., King, J. S., Kinsella, T. J., Kirkin, V., Kirshenbaum, L. A., Kitamoto, K., Kitazato, K., Klein, L., Klimecki, W. T., Klucken, J., Knecht, E., Ko, B. C. B., Koch, J. C., Koga, H., Koh, J. Y., Koh, Y. H., Koike, M., Komatsu, M., Kominami, E., Kong, H. J., Kong, W. J., Korolchuk, V. I., Kotake, Y., Koukourakis, M. I., Kouri Flores, J. B., Kovács, A. L., Kraft, C., Krainc, D., Krämer, H., Kretz-Remy, C., Krichevsky, A. M., Kroemer, G., Krüger, R., Krut, O., Ktistakis, N. T., Kuan, C. Y., Kucharczyk, R., Kumar, A., Kumar, R., Kumar, S., Kundu, M., Kung, H. J., Kurz, T., Kwon, H. J., La Spada, A. R., Lafont, F., Lamark, T., Landry, J., Lane, J. D., Lapaquette, P., Laporte, J. F., László, L., Lavandero, S., Lavoie, J. N., Layfield, R., Lazo, P. A., Le, W., Le Cam, L., Ledbetter, D. J., Lee, A. J. X., Lee, B. W., Lee, G. M., Lee, J., Lee, J. H., Lee, M., Lee, M. S., Lee, S. H., Leeuwenburgh, C., Legembre, P., Legouis, R., Lehmann, M., Lei, H. Y., Lei, Q. Y., Leib, D. A., Leiro, J., Lemasters, J. J., Lemoine, A., Lesniak, M. S., Lev, D., Levenson, V. V., Levine, B., Levy, E., Li, F., Li, J. 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E., Palumbo, C., Pan, T., Panaretakis, T., Pandey, U. B., Papackova, Z., Papassideri, I., Paris, I., Park, J., Park, O. K., Parys, J. B., Parzych, K. R., Patschan, S., Patterson, C., Pattingre, S., Pawelek, J. M., Peng, J., Perlmutter, D. H., Perrotta, I., Perry, G., Pervaiz, S., Peter, M., Peters, G. J., Petersen, M., Petrovski, G., Phang, J. M., Piacentini, M., Pierre, P., Pierrefite-Carle, V., Pierron, G., Pinkas-Kramarski, R., Piras, A., Piri, N., Platanias, L. C., Pöggeler, S., Poirot, M., Poletti, A., Poüs, C., Pozuelo-Rubio, M., Prætorius-Ibba, M., Prasad, A., Prescott, M., Priault, M., Produit-Zengaffinen, N., Progulske-Fox, A., Proikas-Cezanne, T., Przedborski, S., Przyklenk, K., Puertollano, R., Puyal, J., Qian, S. B., Qin, L., Qin, Z. H., Quaggin, S. E., Raben, N., Rabinowich, H., Rabkin, S. W., Rahman, I., Rami, A., Ramm, G., Randall, G., Randow, F., Rao, V. A., Rathmell, J. C., Ravikumar, B., Ray, S. K., Reed, B. H., Reed, J. C., Reggiori, F., Régnier-Vigouroux, A., Reichert, A. S., Reiners, J. J., Reiter, R. J., Ren, J., Revuelta, J. L., Rhodes, C. J., Ritis, K., Rizzo, E., Robbins, J., Roberge, M., Roca, H., Roccheri, M. C., Rocchi, S., Rodemann, H. P., De Córdoba, S. R., Rohrer, B., Roninson, I. B., Rosen, K., Rost-Roszkowska, M. M., Rouis, M., Rouschop, K. M. A., Rovetta, F., Rubin, B. P., Rubinsztein, D. C., Ruckdeschel, K., Rucker, E. B., Rudich, A., Rudolf, E., Ruiz-Opazo, N., Russo, R., Rusten, T. E., Ryan, K. M., Ryter, S. W., Sabatini, D. M., Sadoshima, J., Saha, T., Saitoh, T., Sakagami, H., Sakai, Y., Salekdeh, G. H., Salomoni, P., Salvaterra, P. M., Salvesen, G., Salvioli, R., Sanchez, A. M. J., Sánchez-Alcázar, J. A., Sánchez-Prieto, R., Sandri, M., Sankar, U., Sansanwal, P., Santambrogio, L., Saran, S., Sarkar, S., Sarwal, M., Sasakawa, C., Sasnauskiene, A., Sass, M., Sato, K., Sato, M., Schapira, A. H. V., Scharl, M., Schätzl, H. M., Scheper, W., Schiaffino, S., Schneider, C., Schneider, M. E., Schneider-Stock, R., Schoenlein, P. V., Schorderet, D. F., Schüller, C., Schwartz, G. K., Scorrano, L., Sealy, L., Seglen, P. O., Segura-Aguilar, J., Seiliez, I., Seleverstov, O., Sell, C., Seo, J. B., Separovic, D., Setaluri, V., Setoguchi, T., Settembre, C., Shacka, J. J., Shanmugam, M., Shapiro, I. M., Shaulian, E., Shaw, R. J., Shelhamer, J. H., Shen, H. M., Shen, W. C., Sheng, Z. H., Shi, Y., Shibuya, K., Shidoji, Y., Shieh, J. J., Shih, C. M., Shimada, Y., Shimizu, S., Shintani, T., Shirihai, O. S., Shore, G. C., Sibirny, A. A., Sidhu, S. B., Sikorska, B., Silva-Zacarin, E. C. M., Simmons, A., Simon, A. K., Simon, H. U., Simone, C., Simonsen, A., Sinclair, D. A., Singh, R., Sinha, D., Sinicrope, F. A., Sirko, A., Siu, P. M., Sivridis, E., Skop, V., Skulachev, V. P., Slack, R. S., Smaili, S. S., Smith, D. R., Soengas, M. S., Soldati, T., Song, X., Sood, A. K., Soong, T. W., Sotgia, F., Spector, S. A., Spies, C. D., Springer, W., Srinivasula, S. M., Stefanis, L., Steffan, J. S., Stendel, R., Stenmark, H., Stephanou, A., Stern, S. T., Sternberg, C., Stork, B., Strålfors, P., Subauste, C. S., Sui, X., Sulzer, D., Sun, J., Sun, S. Y., Sun, Z. J., Sung, J. J. Y., Suzuki, K., Suzuki, T., Swanson, M. S., Swanton, C., Sweeney, S. T., Sy, L. K., Szabadkai, G., Tabas, I., Taegtmeyer, H., Tafani, M., Takács-Vellai, K., Takano, Y., Takegawa, K., Takemura, G., Takeshita, F., Talbot, N. J., Tan, K. S. W., Tanaka, K., Tanaka, K., Tang, D., Tang, D., Tanida, I., Tannous, B. A., Tavernarakis, N., Taylor, G. S., Taylor, G. A., Taylor, J. P., Terada, A. S., Terman, A., Tettamanti, G., Thevissen, K., Thompson, C. B., Thorburn, A., Thumm, M., Tian, F., Tian, Y., Tocchini-Valentini, G., Tolkovsky, A. M., Tomino, Y., Tönges, L., Tooze, S. A., Tournier, C., Tower, J., Towns, R., Trajkovic, V., Travassos, L. H., Tsai, T. F., Tschan, M. P., Tsubata, T., Tsung, A., Turk, B., Turner, L. S., Tyagi, S. C., Uchiyama, Y., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Unni, V. 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K. K., Wyttenbach, A., Xavier, R. J., Xi, Z., Xia, P., Xiao, G., Xie, Z., Xie, Z., Xu, D. Z., Xu, J., Xu, L., Xu, X., Yamamoto, A., Yamamoto, A., Yamashina, S., Yamashita, M., Yan, X., Yanagida, M., Yang, D. S., Yang, E., Yang, J. M., Yang, S. Y., Yang, W., Yang, W. Y., Yang, Z., Yao, M. C., Yao, T. P., Yeganeh, B., Yen, W. L., Yin, J. J., Yin, X. M., Yoo, O. J., Yoon, G., Yoon, S. Y., Yorimitsu, T., Yoshikawa, Y., Yoshimori, T., Yoshimoto, K., You, H. J., Youle, R. J., Younes, A., Yu, L., Yu, L., Yu, S. W., Yu, W. H., Yuan, Z. M., Yue, Z., Yun, C. H., Yuzaki, M., Zabirnyk, O., Silva-Zacarin, E., David Zacks, E., Zacksenhaus, L., Zaffaroni, N., Zakeri, Z., Zeh, H. J., Zeitlin, S. O., Zhang, H., Zhang, H. L., Zhang, J., Zhang, J. P., Zhang, L., Zhang, L., Zhang, M. Y., Zhang, X. D., Zhao, M., Zhao, Y. F., Zhao, Y., Zhao, Z. J., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, C. Z., Zhu, C., Zhu, W. G., Zhu, X. F., Zhu, X., Zhu, Y., Zoladek, T., Zong, W. X., Zorzano, A., Zschocke, J. & Zuckerbraun, B., Apr 2012, In : Autophagy. 8, 4, p. 445-544 100 p.

Research output: Contribution to journalArticle

Autophagy
Guidelines
Lysosomes
Eukaryota
Research Personnel
6 Citations (Scopus)

Inhibiting glycogen synthase kinase-3 decreases 12-O-tetradecanoylphorbol- 13-acetate-induced interferon-γ-mediated skin inflammation

Hsieh, C-Y., Chen, C-L., Tsai, C-C., Huang, W-C., Tseng, P-C., Lin, Y-S., Chen, S-H., Wong, T-W., Choi, P-C. & Lin, C. F., Oct 2012, In : Journal of Pharmacology and Experimental Therapeutics. 343, 1, p. 125-133 9 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Tetradecanoylphorbol Acetate
Interferons
Inflammation
Skin
27 Citations (Scopus)

Interferon-γ stimulates p11-dependent surface expression of annexin A2 in lung epithelial cells to enhance phagocytosis

Fang, Y. T., Lin, C. F., Wang, C. Y., Anderson, R. & Lin, Y. S., Jun 2012, In : Journal of Cellular Physiology. 227, 6, p. 2775-2787 13 p.

Research output: Contribution to journalArticle

Annexin A2
Phagocytosis
Interferons
Epithelial Cells
Lung
27 Citations (Scopus)

Regulation of SHP2 by PTEN/AKT/GSK-3β signaling facilitates IFN-γ resistance in hyperproliferating gastric cancer

Tseng, P-C., Huang, W-C., Chen, C-L., Sheu, B-S., Shan, Y-S., Tsai, C-C., Wang, C-Y., Chen, S-O., Hsieh, C-Y. & Lin, C. F., Sep 2012, In : Immunobiology. 217, 9, p. 926-934 9 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Stomach Neoplasms
Phosphatidylinositol 3-Kinases
SH2 Domain-Containing Protein Tyrosine Phosphatases
Mitogen-Activated Protein Kinase Kinases
13 Citations (Scopus)

Urinary macrophage migration inhibitory factor serves as a potential biomarker for acute kidney injury in patients with acute pyelonephritis

Hong, M-Y., Tseng, C-C., Chuang, C-C., Chen, C-L., Lin, S-H. & Lin, C. F., 2012, In : Mediators of Inflammation. 2012, 381358.

Research output: Contribution to journalArticle

Macrophage Migration-Inhibitory Factors
Pyelonephritis
Acute Kidney Injury
Biomarkers
Kidney
65 Citations (Scopus)

Vinca alkaloids cause aberrant ROS-mediated JNK activation, Mcl-1 downregulation, DNA damage, mitochondrial dysfunction, and apoptosis in lung adenocarcinoma cells

Chiu, W-H., Luo, S-J., Chen, C-L., Cheng, J-H., Hsieh, C-Y., Wang, C-Y., Huang, W-C., Su, W-C. & Lin, C. F., May 1 2012, In : Biochemical Pharmacology. 83, 9, p. 1159-1171 13 p.

Research output: Contribution to journalArticle

Vinca Alkaloids
Myeloid Leukemia
JNK Mitogen-Activated Protein Kinases
Myeloid Cells
DNA Damage
43 Citations (Scopus)

α2-Adrenoceptor agonist dexmedetomidine protects septic acute kidney injury through increasing BMP-7 and inhibiting HDAC2 and HDAC5

Hsing, C-H., Lin, C-F., So, E., Sun, D. P., Chen, T. C., Li, C. F. & Yeh, C. H., Nov 15 2012, In : American Journal of Physiology - Renal Physiology. 303, 10

Research output: Contribution to journalArticle

Bone Morphogenetic Protein 7
Dexmedetomidine
Acute Kidney Injury
Adrenergic Receptors
Histone Deacetylases
2011
27 Citations (Scopus)

ACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells

Chang, Y. S., Tsai, C. T., Huangfu, C. A., Huang, W. Y., Lei, H. Y., Lin, C. F., Su, I. J., Chang, W. T., Wu, P. H., Chen, Y. T., Hung, J. H., Young, K. C. & Lai, M. D., Mar 2011, In : Journal of Cellular Biochemistry. 112, 3, p. 881-893 13 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Endoplasmic Reticulum Stress
Liver
Up-Regulation
Lipids
71 Citations (Scopus)

Anesthetic propofol reduces endotoxic inflammation by inhibiting reactive oxygen species-regulated Akt/IKKβ/NF-κB signaling

Hsing, C-H., Lin, M-C., Choi, P-C., Huang, W-C., Kai, J-I., Tsai, C-C., Cheng, Y-L., Hsieh, C-Y., Wang, C-Y., Chang, Y-P., Chen, Y-H., Chen, C-L. & Lin, C-F., 2011, In : PLoS One. 6, 3, e17598.

Research output: Contribution to journalArticle

Propofol
anesthetics
lipopolysaccharides
Lipopolysaccharides
Anesthetics

Apoptotic sphingolipid ceramide in cancer therapy

Huang, W. C., Chen, C. L., Lin, Y. S. & Lin, C-F., 2011, In : Journal of Lipids.

Research output: Contribution to journalReview article

Sphingolipids
Ceramides
Neoplasms
Apoptosis
Therapeutics
11 Citations (Scopus)

Autophagy facilitates an IFN-γ response and signal transduction

Chang, Y-P., Chen, C-L., Chen, S-O., Lin, Y-S., Tsai, C-C., Huang, W-C., Wang, C-Y., Hsieh, C-Y., Choi, P-C. & Lin, C. F., Oct 2011, In : Microbes and Infection. 13, 11, p. 888-894 7 p.

Research output: Contribution to journalArticle

Autophagy
Signal Transduction
Down-Regulation
Inflammation
16 Citations (Scopus)

Dermatophagoides pteronyssinus 2 regulates nerve growth factor release to induce airway inflammation via a reactive oxygen species-dependent pathway

Ye, Y. L., Wu, H. T., Lin, C. F., Hsieh, C. Y., Wang, J. Y., Liu, F. H., Ma, C. T., Bei, C. H., Cheng, Y. L., Chen, C. C., Chiang, B. L. & Tsao, C. W., Feb 2011, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 300, 2

Research output: Contribution to journalArticle

Dermatophagoides pteronyssinus
Neurotrophin 3
Nerve Growth Factor
Reactive Oxygen Species
Dermatophagoides Antigens
10 Citations (Scopus)

Dextromethorphan efficiently increases bactericidal activity, attenuates inflammatory responses, and prevents group A streptococcal sepsis

Li, M. H., Luo, Y. H., Lin, C. F., Chang, Y. T., Lu, S. L., Kuo, C. F., Hong, J. S. & Lin, Y. S., Mar 2011, In : Antimicrobial Agents and Chemotherapy. 55, 3, p. 967-973 7 p.

Research output: Contribution to journalArticle

Dextromethorphan
Sepsis
Streptococcus
Air
Infection
34 Citations (Scopus)

Glucosylceramide synthase inhibitor PDMP sensitizes chronic myeloid leukemia T315I mutant to Bcr-Abl inhibitor and cooperatively induces glycogen synthase kinase-3-regulated apoptosis

Huang, W. C., Tsai, C. C., Chen, C. L., Chen, T. Y., Chen, Y. P., Lin, Y. S., Lu, P. J., Lin, C. M., Wang, S. H., Tsao, C. W., Wang, C. Y., Cheng, Y. L., Hsieh, C. Y., Tseng, P. C. & Lin, C. F., Oct 2011, In : FASEB Journal. 25, 10, p. 3661-3673 13 p.

Research output: Contribution to journalArticle

ceramide glucosyltransferase
Glycogen Synthase Kinase 3
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Apoptosis
Ceramides
5 Citations (Scopus)

Glycogen synthase kinase-3 facilitates con a-induced IFN-γ-mediated immune hepatic injury

Tsai, C-C., Huang, W-C., Chen, C-L., Hsieh, C-Y., Lin, Y-S., Chen, S-H., Yang, K-C. & Lin, C. F., Oct 1 2011, In : Journal of Immunology. 187, 7, p. 3867-3877 11 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Liver
Wounds and Injuries
Inbred C57BL Mouse
Hepatocytes
25 Citations (Scopus)

Increased galectin-3 facilitates leukemia cell survival from apoptotic stimuli

Cheng, Y-L., Huang, W-C., Chen, C-L., Tsai, C-C., Wang, C-Y., Chiu, W-H., Chen, Y-L., Lin, Y-S., Chang, C-F. & Lin, C. F., Aug 26 2011, In : Biochemical and Biophysical Research Communications. 412, 2, p. 334-340 7 p.

Research output: Contribution to journalArticle

Galectin 3
Cell Survival
Leukemia
Cells
Glycogen Synthase Kinase 3
36 Citations (Scopus)

Inhibition of neutrophil apoptosis via sphingolipid signaling in acute lung injury

Lin, W-C., Lin, C. F., Chen, C-L., Chen, C-W. & Lin, Y-S., Oct 2011, In : Journal of Pharmacology and Experimental Therapeutics. 339, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

Sphingolipids
Acute Lung Injury
Neutrophils
Apoptosis
Lipopolysaccharides
13 Citations (Scopus)

Mechanisms underlying Benzyl alcohol cytotoxicity (triamcinolone acetonide preservative) in human retinal pigment epithelial cells

Chang, Y. S., Lin, C. F., Wu, C. L., Kuo, P. Y., Wu, F. S., Shieh, C. C., Gean, P. W., Chen, S. T., Chen, M. S., Wu, W. C., Tai, M. H. & Tseng, S. H., Jun 2011, In : Investigative Ophthalmology and Visual Science. 52, 7, p. 4214-4222 9 p.

Research output: Contribution to journalArticle

Benzyl Alcohol
Triamcinolone Acetonide
Retinal Pigments
Epithelial Cells
Caspases
67 Citations (Scopus)

Molecular mimicry between virus and host and its implications for dengue disease pathogenesis

Lin, Y. S., Yeh, T. M., Lin, C. F., Wan, S. W., Chuang, Y. C., Hsu, T. K., Liu, H. S., Liu, C. C., Anderson, R. & Lei, H. Y., May 2011, In : Experimental Biology and Medicine. 236, 5, p. 515-523 9 p.

Research output: Contribution to journalArticle

Molecular Mimicry
Dengue
Dengue Virus
Viruses
Proteins
7 Citations (Scopus)

The acid sphingomyelinase inhibitors block interferon-α-induced serotonin uptake via a COX-2/Akt/ERK/STAT-dependent pathway in T cells

Su, H. C., Ma, C. T., Lin, C. F., Wu, H. T., Chuang, Y. H., Chen, L. J. & Tsao, C. W., Nov 2011, In : International Immunopharmacology. 11, 11, p. 1823-1831 9 p.

Research output: Contribution to journalArticle

Sphingomyelin Phosphodiesterase
Trans-Activators
Mitogen-Activated Protein Kinase 1
Transducers
Interferon-alpha
2010
57 Citations (Scopus)

Altered inflammatory responses in preterm children with cerebral palsy

Lin, C. Y., Chang, Y. C., Wang, S. T., Lee, T. Y., Lin, C. F. & Huang, C. C., 2010, In : Annals of Neurology. 68, 2, p. 204-212 9 p.

Research output: Contribution to journalArticle

Cerebral Palsy
Blood Cells
Periventricular Leukomalacia
Tumor Necrosis Factor-alpha
Lipopolysaccharides
10 Citations (Scopus)

Annexin A2 on lung epithelial cell surface is recognized by severe acute respiratory syndrome-associated coronavirus spike domain 2 antibodies

Fang, Y. T., Lin, C. F., Liao, P. C., Kuo, Y. M., Wang, S., Yeh, T. M., Shieh, C. C. K., Su, I. J., Lei, H. Y. & Lin, Y. S., Feb 2010, In : Molecular Immunology. 47, 5, p. 1000-1009 10 p.

Research output: Contribution to journalArticle

Annexin A2
Severe Acute Respiratory Syndrome
Coronavirus
Epithelial Cells
Lung
9 Citations (Scopus)

Autocrine IL-6 regulates GRO-α production in thymic epithelial cells

Tseng, Y. L., Wu, M. H., Yang, H. C., Wang, C. Y. & Lin, C. F., Aug 2010, In : Cytokine. 51, 2, p. 195-201 7 p.

Research output: Contribution to journalArticle

Oncogenes
Interleukin-6
Epithelial Cells
Growth
Janus Kinase 2
62 Citations (Scopus)

Autophagy facilitates IFN-δ-induced Jak2-STAT1 activation and cellular inflammation

Chang, Y-P., Tsai, C-C., Huang, W-C., Wang, C-Y., Chen, C-L., Lin, Y-S., Kai, J-I., Hsieh, C-Y., Cheng, Y-L., Choi, P-C., Chen, S-H., Chang, S-P., Liu, H-S. & Lin, C. F., Sep 10 2010, In : Journal of Biological Chemistry. 285, 37, p. 28715-28722 8 p.

Research output: Contribution to journalArticle

Autophagy
Fibroblasts
Chemical activation
Inflammation
Class III Phosphatidylinositol 3-Kinases