• 806 Citations
  • 17 h-Index
20032020

Research output per year

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Research Output

  • 806 Citations
  • 17 h-Index
  • 39 Article
  • 1 Comment/debate
2020

Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell migration via PKCα-mediated AHR-HDAC interactions

Tsai, C. H., Li, C. H., Liao, P. L., Chang, Y. W., Cheng, Y. W. & Kang, J. J., Feb 2020, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1867, 2, 118564.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The functional interplay of lncRNA EGOT and HuR regulates hypoxia-induced autophagy in renal tubular cells

Wang, I. K., Palanisamy, K., Sun, K. T., Yu, S. H., Yu, T. M., Li, C. H., Lin, F. Y., Chou, A. K., Wang, G. J., Chen, K. B. & Li, C. Y., Jan 1 2020, (Accepted/In press) In : Journal of Cellular Biochemistry.

Research output: Contribution to journalArticle

2019

Chloramphenicol induces autophagy and inhibits the hypoxia inducible factor-1 alpha pathway in non-small cell lung cancer cells

Hsu, H. L., Liao, P. L., Cheng, Y. W., Huang, S. H., Wu, C. H., Li, C. H. & Kang, J. J., Jan 1 2019, In : International Journal of Molecular Sciences. 20, 1, 157.

Research output: Contribution to journalArticle

4 Citations (Scopus)
Open Access

Down-regulation of aryl hydrocarbon receptor intensifies carcinogen-induced retinal lesion via SOCS3-STAT3 signaling

Tsai, C. H., Lee, Y., Li, C. H., Cheng, Y. W. & Kang, J. J., Jan 1 2019, (Accepted/In press) In : Cell Biology and Toxicology.

Research output: Contribution to journalArticle

Glycemia Lowering Effect of an Aqueous Extract of Hedychium coronarium Leaves in Diabetic Rodent Models

Tse, L. S., Liao, P. L., Tsai, C. H., Li, C. H., Liao, J. W., Kang, J. J. & Cheng, Y. W., Mar 14 2019, In : Nutrients. 11, 3

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
Open Access

Thermally stable and uniform DNA amplification with picosecond laser ablated graphene rapid thermal cycling device

Chen, Z. C., Chang, T. L., Li, C. H., Su, K. W. & Liu, C. C., Dec 15 2019, In : Biosensors and Bioelectronics. 146, 111581.

Research output: Contribution to journalArticle

Open Access
2018

Role of activating transcription factor 3 in fructose-induced metabolic syndrome in mice

Chou, C. L., Li, C. H., Lin, H., Liao, M. H., Wu, C. C., Chen, J. S., Sue, Y. M. & Fang, T. C., Aug 1 2018, In : Hypertension Research. 41, 8, p. 589-597 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Safety assessment of the Cistanche tubulosa health food product Memoregain®: Genotoxicity and 28-day repeated dose toxicity test

Liao, P. L., Li, C. H., Tse, L. S., Kang, J. J. & Cheng, Y. W., Aug 1 2018, In : Food and Chemical Toxicology. 118, p. 581-588 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2017

Anti-inflammatory properties of shikonin contribute to improved early-stage diabetic retinopathy

Liao, P. L., Lin, C. H., Li, C. H., Tsai, C. H., Ho, J. D., Chiou, G. C. Y., Kang, J. J. & Cheng, Y. W., Mar 21 2017, In : Scientific Reports. 7, 44985.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial–mesenchymal transition in non-small cell lung cancer cells

Li, C. H., Liu, C. W., Tsai, C. H., Peng, Y. J., Yang, Y. H., Liao, P. L., Lee, C. C., Cheng, Y. W. & Kang, J. J., May 1 2017, In : Archives of Toxicology. 91, 5, p. 2165-2178 14 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Periodic exposure to smartphone-mimic low-luminance blue light induces retina damage through Bcl-2/BAX-dependent apoptosis

Lin, C. H., Wu, M. R., Li, C. H., Cheng, H. W., Huang, S. H., Tsai, C. H., Lin, F. L., Ho, J. D., Kang, J. J., Hsiao, G. & Cheng, Y. W., May 1 2017, In : Toxicological Sciences. 157, 1, p. 196-210 15 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The inhibition of lung cancer cell migration by AhR-regulated autophagy

Tsai, C. H., Li, C. H., Cheng, Y. W., Lee, C. C., Liao, P. L., Lin, C. H., Huang, S. H. & Kang, J. J., Feb 14 2017, In : Scientific Reports. 7, 41927.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2016

Ligand independent aryl hydrocarbon receptor inhibits lung cancer cell invasion by degradation of Smad4

Lee, C. C., Yang, W. H., Li, C. H., Cheng, Y. W., Tsai, C. H. & Kang, J. J., Jul 1 2016, In : Cancer Letters. 376, 2, p. 211-217 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2015

Gold nanoparticles increase endothelial paracellular permeability by altering components of endothelial tight junctions, and increase blood-brain barrier permeability in mice

Li, C. H., Shyu, M. K., Jhan, C., Cheng, Y. W., Tsai, C. H., Liu, C. W., Lee, C. C., Chen, R. M. & Kang, J. J., Nov 1 2015, In : Toxicological Sciences. 148, 1, p. 192-203 12 p., kfv176.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Long-term Fluorometholone Topical Use Induces Ganglion Cell Damage in Rats Analyzed With Optical Coherence Tomography

Lin, C. H., Liao, P. L., Hsiao, G., Li, C. H., Huang, S. H., Tsai, C. H., Wu, M. R., Lin, F. L., Ho, J. D., Cheng, H. W. & Cheng, Y. W., Oct 1 2015, In : Toxicological Sciences. 147, 2, p. 317-325 9 p., kfv132.

Research output: Contribution to journalArticle

5 Citations (Scopus)

NcoA2-dependent inhibition of HIF-1α activation is regulated via AhR

Tsai, C. H., Li, C. H., Liao, P. L., Cheng, Y. W., Lin, C. H., Huang, S. H. & Kang, J. J., Dec 1 2015, In : Toxicological Sciences. 148, 2, p. 517-530 14 p., kfv199.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2014

Minocycline accelerates hypoxia-inducible factor-1 alpha degradation and inhibits hypoxia-induced neovasculogenesis through prolyl hydroxylase, von Hippel-Lindau-dependent pathway

Li, C. H., Liao, P. L., Yang, Y. T., Huang, S. H., Lin, C. H., Cheng, Y. W. & Kang, J. J., Mar 2014, In : Archives of Toxicology. 88, 3, p. 659-671 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Snail regulates Nanog status during the epithelial-mesenchymal transition via the Smad1/Akt/GSK3β signaling pathway in non-small-cell lung cancer

Liu, C. W., Li, C. H., Peng, Y. J., Cheng, Y. W., Chen, H. W., Liao, P. L., Kang, J. J. & Yeng, M. H., 2014, In : Oncotarget. 5, 11, p. 3880-3894 15 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Zinc oxide nanoparticles impair bacterial clearance by macrophages

Lin, C. D., Kou, Y. Y., Liao, C. Y., Li, C. H., Huang, S. P., Cheng, Y. W., Liao, W. C., Chen, H. X., Wu, P. L., Kang, J. J., Lee, C. C. & Lai, C. H., Jul 1 2014, In : Nanomedicine. 9, 9, p. 1327-1339 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2013

Evaluation of acute 13-week subchronic toxicity and genotoxicity of the powdered root of Tongkat Ali (Eurycoma Longifolia Jack)

Li, C. H., Liao, J. W., Liao, P. L., Huang, W. K., Tse, L. S., Lin, C. H., Kang, J. J. & Cheng, Y. W., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 102987.

Research output: Contribution to journalArticle

20 Citations (Scopus)
42 Citations (Scopus)
2012

Anti-ageing effects of alpha-naphthoflavone on normal and UVB-irradiated human skin fibroblasts

Liao, P. L., Li, C. H., Chang, C. Y., Lu, S. R., Lin, C. H., Tse, L. S. & Cheng, Y. W., Jul 2012, In : Experimental Dermatology. 21, 7, p. 546-548 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Motorcycle exhaust particles up-regulate expression of vascular adhesion molecule-1 and intercellular adhesion molecule-1 in human umbilical vein endothelial cells

Lee, C. C., Huang, S. H., Yang, Y. T., Cheng, Y. W., Li, C. H. & Kang, J. J., Jun 2012, In : Toxicology in Vitro. 26, 4, p. 552-560 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Organ biodistribution, clearance, and genotoxicity of orally administered zinc oxide nanoparticles in mice

Li, C. H., Shen, C. C., Cheng, Y. W., Huang, S. H., Wu, C. C., Kao, C. C., Liao, J. W. & Kang, J. J., Nov 2012, In : Nanotoxicology. 6, 7, p. 746-756 11 p.

Research output: Contribution to journalArticle

144 Citations (Scopus)

Zinc oxide nanoparticles-induced intercellular adhesion molecule 1 expression requires Rac1/Cdc42, mixed lineage kinase 3, and c-Jun N-terminal kinase activation in endothelial cells

Li, C. H., Liao, P. L., Shyu, M. K., Liu, C. W., Kao, C. C., Huang, S. H., Cheng, Y. W. & Kang, J. J., 2012, In : Toxicological Sciences. 126, 1, p. 162-172 11 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2010
15 Citations (Scopus)

Benzo[a]pyrene inhibits angiogenic factors-induced αvβ3 integrin expression, neovasculogenesis, and angiogenesis in human umbilical vein endothelial cells

Li, C. H., Cheng, Y. W., Hsu, Y. T., Hsu, Y. J., Liao, P. L. & Kang, J. J., Dec 2010, In : Toxicological Sciences. 118, 2, p. 544-553 10 p., kfq279.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Chloramphenicol causes mitochondrial stress, decreases ATP biosynthesis, induces matrix metalloproteinase-13 expression, and solid-tumor cell invasion

Li, C. H., Cheng, Y. W., Liao, P. L., Yang, Y. T. & Kang, J. J., Mar 25 2010, In : Toxicological Sciences. 116, 1, p. 140-150 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Safety assessment of musk substitute from nutria of Myocastor coypus in mice

Yu, W. C., Horng, Y. L., Shoei, S. L., Jun, W. L., Hui, W. C., Ching, H. L., Po, L. L. & Jaw, J. K., Dec 2010, In : Journal of Food and Drug Analysis. 18, 6, p. 380-390 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2009

Cholesterol-3-beta, 5-alpha, 6-beta-triol induced PI3K-Akt-eNOS-dependent cyclooxygenase-2 expression in endothelial cells

Liao, P. L., Cheng, Y. W., Li, C. H., Lo, Y. L. & Kang, J. J., Oct 28 2009, In : Toxicology Letters. 190, 2, p. 172-178 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2006

Physiological and functional interactions between Tcf4 and Daxx in colon cancer cells

Tzeng, S. L., Cheng, Y. W., Li, C. H., Lin, Y. S., Hsu, H. C. & Kang, J. J., Jun 2 2006, In : Journal of Biological Chemistry. 281, 22, p. 15405-15411 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2005

Chloramphenicol-induced mitochondrial stress increases p21 expression and prevents cell apoptosis through a p21-dependent pathway

Li, C. H., Tzeng, S. L., Cheng, Y. W. & Kang, J. J., Jul 15 2005, In : Journal of Biological Chemistry. 280, 28, p. 26193-26199 7 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)
2004

Activation and up-regulation of nitric oxide synthase in human umbilical vein endothelial cells by polycyclic aromatic hydrocarbons

Li, C. H., Lee, C. C., Cheng, Y. W., Juang, H. A. & Kang, J. J., Jul 15 2004, In : Toxicology Letters. 151, 2, p. 367-374 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Genotoxicity of motorcycle exhaust particles in vivo and in vitro

Cheng, Y. W., Lee, W. W., Li, C. H., Lee, C. C. & Kang, J. J., Sep 2004, In : Toxicological Sciences. 81, 1, p. 103-111 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Reactive oxygen species are crucial for hydroxychavicol toxicity toward KB epithelial cells

Jeng, J. H., Wang, Y. J., Chang, W. H., Wu, H. L., Li, C. H., Uang, B. J., Kang, J. J., Lee, J. J., Hahn, L. J., Lin, B. R. & Chang, M. C., Jan 2004, In : Cellular and Molecular Life Sciences. 61, 1, p. 83-96 14 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2003
9 Citations (Scopus)

Induction of vasorelaxation through activation of nitric oxide synthase in endothelial cells by brazilin

Hu, C. M., Kang, J. J., Lee, C. C., Li, C. H., Liao, J. W. & Cheng, Y. W., May 2 2003, In : European Journal of Pharmacology. 468, 1, p. 37-45 9 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)