• 2308 Citations
  • 16 h-Index
19952020

Research output per year

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Research Output

2020

Circuit Integration Initiation of New Hippocampal Neurons in the Adult Brain

Yang, C. H., Di Antonio, A., Kirschen, G. W., Varma, P., Hsieh, J. & Ge, S., Jan 28 2020, In : Cell Reports. 30, 4, p. 959-968.e3

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2019

A critical period for the development of schizophrenia-like pathology by aberrant postnatal neurogenesis

Sheu, J. R., Hsieh, C. Y., Jayakumar, T., Tseng, M. F., Lee, H. N., Huang, S. W., Manubolu, M. & Yang, C. H., Jan 1 2019, In : Frontiers in Neuroscience. 13, JUN, 635.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Correction to: Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital (Neurotherapeutics, (2015), 12, 2, (477-490), 10.1007/s13311-015-0343-0)

Ma, D., Yoon, S. I., Yang, C. H., Marcy, G., Zhao, N., Leong, W. Y., Ganapathy, V., Han, J., Van Dongen, A. M. J., Hsu, K. S., Ming, G. L., Augustine, G. J. & Goh, E. L. K., Jan 1 2019, In : Neurotherapeutics.

Research output: Contribution to journalErratum

Open Access

HDAC6 dysfunction contributes to impaired maturation of adult neurogenesis in vivo: vital role on functional recovery after ischemic stroke

Sheu, J-R., Hsieh, C-Y., Jayakumar, T., Lin, G-Y., Lee, H-N., Huang, S-W. & Yang, C-H., Apr 18 2019, In : Journal of Biomedical Science. 26, 1, 27.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Hirsutanol A attenuates lipopolysaccharide-mediated matrix metalloproteinase 9 expression and cytokines production and improves endotoxemia-induced acute sickness behavior and acute lung injury

Jan, J. S., Yang, C. H., Wang, M. H., Lin, F. L., Yen, J. L., Hsieh, I., Khotimchenko, M., Lee, T. H. & Hsiao, G., Jun 17 2019, In : Marine Drugs. 17, 6, 360.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
Open Access
1 Citation (Scopus)
2018

CME-1, a novel polysaccharide, suppresses iNOS expression in lipopolysaccharide-stimulated macrophages through ceramide-initiated protein phosphatase 2A activation

Sheu, J. R., Chen, Z. C., Hsu, M. J., Wang, S. H., Jung, K. W., Wu, W. F., Pan, S. H., Teng, R. D., Yang, C. H. & Hsieh, C. Y., Feb 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 2, p. 999-1013 15 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
Open Access

Hinokitiol inhibits migration of A549 lung cancer cells via suppression of MMPs and induction of antioxidant enzymes and apoptosis

Jayakumar, T., Liu, C. H., Wu, G. Y., Lee, T. Y., Manubolu, M., Hsieh, C. Y., Yang, C. H. & Sheu, J. R., Mar 22 2018, In : International Journal of Molecular Sciences. 19, 4, 939.

Research output: Contribution to journalArticle

6 Citations (Scopus)
4 Citations (Scopus)

Novel iridium (III)-derived organometallic compound for the inhibition of human platelet activation

Shyu, K. G., Velusamy, M., Hsia, C. W., Yang, C. H., Hsia, C. H., Chou, D. S., Jayakumar, T., Sheu, J. R. & Li, J. Y., May 1 2018, In : International Journal of Molecular Medicine. 41, 5, p. 2589-2600 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Structure⁻Activity Relationship Study of Newly Synthesized Iridium-III Complexes as Potential Series for Treating Thrombotic Diseases

Yang, C. H., Hsia, C. W., Jayakumar, T., Sheu, J. R., Hsia, C. H., Khamrang, T., Chen, Y. J., Manubolu, M. & Chang, Y., Nov 19 2018, In : International Journal of Molecular Sciences. 19, 11

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice

Sheu, J. R., Chen, Z. C., Jayakumar, T., Chou, D. S., Yen, T. L., Lee, H. N., Pan, S. H., Hsia, C. H., Yang, C. H. & Hsieh, C. Y., Feb 6 2017, In : Scientific Reports. 7, 42277.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Multi-targeting andrographolide, a novel NF-κB inhibitor, as a potential therapeutic agent for stroke

Yang, C. H., Yen, T. L., Hsu, C. Y., Thomas, P. A., Sheu, J. R. & Jayakumar, T., Aug 1 2017, In : International Journal of Molecular Sciences. 18, 8, 1638.

Research output: Contribution to journalReview article

43 Citations (Scopus)
2016
34 Citations (Scopus)

The pharmacodynamics of antiplatelet compounds in thrombosis treatment

Jayakumar, T., Yang, C. H., Geraldine, P., Yen, T. L. & Sheu, J. R., Jun 2 2016, In : Expert Opinion on Drug Metabolism and Toxicology. 12, 6, p. 615-632 18 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)
2015

Antrodia camphorata Potentiates Neuroprotection against Cerebral Ischemia in Rats via Downregulation of iNOS/HO-1/Bax and Activated Caspase-3 and Inhibition of Hydroxyl Radical Formation

Yang, P. S., Lin, P. Y., Chang, C. C., Yu, M. C., Yen, T. L., Lan, C. C., Jayakumar, T. & Yang, C. H., 2015, In : Evidence-based Complementary and Alternative Medicine. 2015, 232789.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital

Ma, D., Yoon, S. I., Yang, C. H., Marcy, G., Zhao, N., Leong, W. Y., Ganapathy, V., Han, J., Van Dongen, A. M. J., Hsu, K. S., Ming, G. L., Augustine, G. J. & Goh, E. L. K., Apr 1 2015, In : Neurotherapeutics. 12, 2, p. 477-490 14 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2012
23 Citations (Scopus)

Vascular endothelial growth factor-dependent spinogenesis underlies antidepressant-like effects of enriched environment

Huang, Y. F., Yang, C. H., Huang, C. C. & Hsu, K. S., Nov 30 2012, In : Journal of Biological Chemistry. 287, 49, p. 40938-40955 18 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2011

Generalization of fear inhibition by disrupting hippocampal protein synthesis-dependent reconsolidation process

Yang, C. H., Huang, C. C. & Hsu, K. S., Sep 2011, In : Neuropsychopharmacology. 36, 10, p. 1992-2008 17 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2010

Acute stress impairs hippocampal mossy fiber-CA3 long-term potentiation by enhancing cAMP-specific phosphodiesterase 4 activity

Chen, C. C., Yang, C. H., Huang, C. C. & Hsu, K. S., Jun 2010, In : Neuropsychopharmacology. 35, 7, p. 1605-1617 13 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
49 Citations (Scopus)

Vascular endothelial growth factor regulates excitatory synaptic transmission in hippocampal neurons

Huang, Y. F., Yang, C. H., Chiou, C. S., Huang, C. C. & Hsu, K. S., 2010, In : Molecular and Cellular Pharmacology. 2, 4, p. 137-141 5 p.

Research output: Contribution to journalArticle

2009

Estrogen modulates sexually dimorphic contextual fear extinction in rats through estrogen receptor β

Chang, Y. J., Yang, C. H., Liang, Y. C., Yeh, C. M., Huang, C. C. & Hsu, K. S., Nov 2009, In : Hippocampus. 19, 11, p. 1142-1150 9 p.

Research output: Contribution to journalArticle

110 Citations (Scopus)
2008

Differential roles of basolateral and central amygdala on the effects of uncontrollable stress on hippocampal synaptic plasticity

Yang, C. H., Huang, C. C. & Hsu, K. S., 2008, In : Hippocampus. 18, 6, p. 548-563 16 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Phosphatidylinositol 3-kinase activation is required for stress protocol-induced modification of hippocampal synaptic plasticity

Yang, P. C., Yang, C. H., Huang, C. C. & Hsu, K. S., Feb 1 2008, In : Journal of Biological Chemistry. 283, 5, p. 2631-2643 13 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
2007

A Critical Period for Enhanced Synaptic Plasticity in Newly Generated Neurons of the Adult Brain

Ge, S., Yang, C. H., Hsu, K. S., Ming, G. L. & Song, H., May 24 2007, In : Neuron. 54, 4, p. 559-566 8 p.

Research output: Contribution to journalArticle

637 Citations (Scopus)

Disrupted-In-Schizophrenia 1 Regulates Integration of Newly Generated Neurons in the Adult Brain

Duan, X., Chang, J. H., Ge, S., Faulkner, R. L., Kim, J. Y., Kitabatake, Y., Liu, X. B., Yang, C. H., Jordan, J. D., Ma, D. K., Liu, C. Y., Ganesan, S., Cheng, H. J., Ming, G. L., Lu, B. & Song, H., Sep 21 2007, In : Cell. 130, 6, p. 1146-1158 13 p.

Research output: Contribution to journalArticle

482 Citations (Scopus)
2006

Novelty exploration elicits a reversal of acute stress-induced modulation of hippocampal synaptic plasticity in the rat

Yang, C. H., Huang, C. C. & Hsu, K. S., Dec 1 2006, In : Journal of Physiology. 577, 2, p. 601-615 15 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2005

Behavioral stress enhances hippocampal CA1 long-term depression through the blockade of the glutamate uptake

Yang, C. H., Huang, C. C. & Hsu, K. S., Apr 27 2005, In : Journal of Neuroscience. 25, 17, p. 4288-4293 6 p.

Research output: Contribution to journalArticle

143 Citations (Scopus)

Do stress and long-term potentiation share the same molecular mechanisms?

Huang, C. C., Yang, C. H. & Hsu, K. S., Dec 2005, In : Molecular Neurobiology. 32, 3, p. 223-235 13 p.

Research output: Contribution to journalReview article

40 Citations (Scopus)

Neonatal isolation accelerates the developmental switch in the signalling cascades for long-term potentiation induction

Huang, C. C., Chou, P. H., Yang, C. H. & Hsu, K. S., Dec 15 2005, In : Journal of Physiology. 569, 3, p. 789-799 11 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2004
139 Citations (Scopus)
1996

Guillain-Barre syndrome in northern China. The spectrum of neuropathological changes in clinically defined cases [2]

Menkes, D. L., Hood, D. C., Griffin, J. W., Li, C. Y., Ho, T. W., Xue, P., Macko, C., Gao, C. Y., Yang, C., Tian, M., Mishu, B., Cornblath, D. R., McKhann, G. M. & Asbury, A. K., 1996, In : Brain. 119, 2, p. 676-680 5 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)
1995

Guillain-Barré syndrome in northern China: The spectrum of neuropathological changes in clinically defined cases

Griffin, J. W., Li, C. Y., Ho, T. W., Xue, P., Macko, C., Gao, C. Y., Yang, C., Tian, M., Mishu, B., Cornblath, D. R., McKhann, G. M. & Asbury, A. K., Jun 1995, In : Brain. 118, 3, p. 577-595 19 p.

Research output: Contribution to journalArticle

326 Citations (Scopus)