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Research Output 2012 2019

  • 238 Citations
  • 9 h-Index
  • 30 Article
  • 1 Review article
2019
1 Citation (Scopus)

Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy

Chang, T. C., Wei, P. L., Makondi, P. T., Chen, W. T., Huang, C. Y. & Chang, Y. J., Jan 1 2019, In : PLoS One. 14, 1, e0210274.

Research output: Contribution to journalArticle

bromelains
Bromelains
autophagy
Autophagy
colorectal neoplasms
Bioinformatics
Computational Biology
colorectal neoplasms
MicroRNAs
microRNA
1 Citation (Scopus)

Functional effects of let-7g expression in colon cancer metastasis

Chang, C. M., Wong, H. S. C., Huang, C. Y., Hsu, W. L., Maio, Z. F., Chiu, S. J., Tsai, Y. T., Chen, B. K., Wan, Y. J. Y., Wang, J. Y. & Chang, W. C., Apr 1 2019, In : Cancers. 11, 4, 489.

Research output: Contribution to journalArticle

Open Access
Colonic Neoplasms
Colorectal Neoplasms
Neoplasm Metastasis
Neoplasms
Atlases

Glucose-Regulated Protein 94 Modulates the Response of Osteosarcoma to Chemotherapy

Huang, C. Y., Wei, P. L., Wang, J. W., Makondi, P. T., Huang, M. T., Chen, H. A. & Chang, Y. J., Jan 1 2019, In : Disease Markers. 2019, 1 p.

Research output: Contribution to journalArticle

Chemotherapy
Osteosarcoma
gemcitabine
Drug Therapy
Epirubicin

HSPB1 rs2070804 polymorphism is associated with the depth of primary tumor

Hung, C. S., Huang, C. Y., Hsu, Y. W., Makondi, P. T., Chang, W. C., Chang, Y. J., Wang, J. Y. & Wei, P. L., Jan 1 2019, In : Journal of Cellular Biochemistry.

Research output: Contribution to journalArticle

Polymorphism
Tumors
Colorectal Neoplasms
Single Nucleotide Polymorphism
Neoplasms
1 Citation (Scopus)
Propyl Gallate
propyl gallate
autophagy
Autophagy
Cell growth
2018
Dipeptidyl-Peptidase IV Inhibitors
Keratinocytes
Wound Healing
Adiponectin
Medical problems
3 Citations (Scopus)
NF-kappa B
Cyclooxygenase 2
Vascular Endothelial Growth Factor A
Neoplasm Metastasis
Proteins
6 Citations (Scopus)

Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation

Liang, H. H., Huang, C. Y., Chou, C. W., Makondi, P. T., Huang, M. T., Wei, P. L. & Chang, Y. J., Sep 15 2018, In : Life Sciences. 209, p. 43-51 9 p.

Research output: Contribution to journalArticle

HSP27 Heat-Shock Proteins
Curcumin
Autophagy
Colonic Neoplasms
Reactive Oxygen Species
1 Citation (Scopus)

Improvement of hyperglycemia in a murine model of insulin resistance and high glucose- and inflammasome-mediated IL-1β expressions in macrophages by silymarin

Lu, C. P., Huang, C. Y., Wang, S. H., Chiu, C. H., Li, L. H., Hua, K. F. & Wu, T. H., Jun 25 2018, In : Chemico-Biological Interactions. 290, p. 12-18 7 p.

Research output: Contribution to journalArticle

Inflammasomes
Silymarin
Macrophages
Interleukin-1
Hyperglycemia

Maspin enhances the anticancer activity of curcumin in hormone-refractory prostate cancer cells

Cheng, W. L., Huang, C. Y., Tai, C. J., Chang, Y. J. & Hung, C. S., Feb 1 2018, In : Anticancer Research. 38, 2, p. 863-870 8 p.

Research output: Contribution to journalArticle

Curcumin
Prostatic Neoplasms
Hormones
Curcuma
Androgens
lipoproteins
Lipoproteins
Psoriasis
interleukins
imiquimod
HSP27 Heat-Shock Proteins
Colorectal Neoplasms
Neoplasm Metastasis
Molecules
Proteins
5 Citations (Scopus)

The application of non-invasive apoptosis detection sensor (NIADS) on histone deacetylation inhibitor (HDACI)-induced breast cancer cell death

Hsu, K. W., Huang, C. Y., Tam, K. W., Lin, C. Y., Huang, L. C., Lin, C. L., Hsieh, W. S., Chi, W. M., Chang, Y. J., Wei, P. L., Chen, S. T. & Lee, C. H., Feb 2 2018, In : International Journal of Molecular Sciences. 19, 2, 452.

Research output: Contribution to journalArticle

apoptosis
Cell death
death
breast
Histones
2017
7 Citations (Scopus)
HSP27 Heat-Shock Proteins
Intercellular Signaling Peptides and Proteins
Carrier Proteins
Neoplasm Metastasis
Neoplasms
2016

Bioinformatic analyses revealed underlying biological functions correlated with oxaliplatin responsiveness

Klahan, S., Huang, C. C., Chien, S-C., Wu, M. S., Wong, H. S. C., Huang, C. Y., Chang, W. C. & Wei, P. L., Jan 1 2016, In : Tumor Biology. 37, 1, p. 583-590

Research output: Contribution to journalArticle

oxaliplatin
Computational Biology
Colonic Neoplasms
Toll-Like Receptor 5
Therapeutics
12 Citations (Scopus)

Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma

Huang, C. Y., Batzorig, U., Cheng, W. L., Huang, M. T., Chen, W. Y., Wei, P. L. & Chang, Y. J., Apr 1 2016, In : Tumor Biology. 37, 4, p. 4295-4304

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Neoplasms
glucose-regulated proteins
AMP-Activated Protein Kinases
Heterografts
6 Citations (Scopus)

Glucose-regulated protein 94 mediates metastasis by CCT8 and the JNK pathway in hepatocellular carcinoma

Wei, P-L., Huang, C. Y., Tai, C-J., Batzorig, U., Cheng, W. L., Hunag, M. T. & Chang, Y-J., Jun 1 2016, In : Tumor Biology. 37, 6, p. 8219-8227 9 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Hepatocellular Carcinoma
Neoplasm Metastasis
Neoplasms
Wound Healing
1 Citation (Scopus)

Maspin mediates the gemcitabine sensitivity of hormone-independent prostate cancer

Huang, C. Y., Chang, Y. J., Luo, S. D., Uyanga, B., Lin, F. Y., Tai, C. J. & Huang, M. T., Mar 1 2016, In : Tumor Biology. 37, 3, p. 4075-4082

Research output: Contribution to journalArticle

gemcitabine
Prostatic Neoplasms
Hormones
B-Cell Lymphoma
Apoptosis
2 Citations (Scopus)

Silencing A7-nAChR levels increases the sensitivity of gastric cancer cells to ixabepilone treatment

Tu, C. C., Huang, C. Y., Cheng, W. L., Hung, C. S., Chang, Y. J. & Wei, P. L., Jul 1 2016, In : Tumor Biology. 37, 7, p. 9493-9501 9 p.

Research output: Contribution to journalArticle

Cholinergic Receptors
Nicotine
Stomach Neoplasms
Therapeutics
Apoptosis Regulatory Proteins
7 Citations (Scopus)

The α7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to taxanes

Tu, C. C., Huang, C. Y., Cheng, W. L., Hung, C. S., Uyanga, B., Wei, P. L. & Chang, Y. J., Apr 1 2016, In : Tumor Biology. 37, 4, p. 4421-4428

Research output: Contribution to journalArticle

Taxoids
Nicotinic Receptors
Stomach Neoplasms
Paclitaxel
docetaxel
2015
8 Citations (Scopus)

Alpha 7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to 5-fluorouracil

Chen, W-Y., Huang, C. Y., Cheng, W. L., Hung, C-S., Huang, M-T., Tai, C-J., Liu, Y-N., Chen, C-L. & Chang, Y-J., Jul 3 2015, (Accepted/In press) In : Tumor Biology. 36, 12, p. 9537-9544

Research output: Contribution to journalArticle

Nicotinic Receptors
Fluorouracil
Stomach Neoplasms
In Situ Nick-End Labeling
Cell Cycle
20 Citations (Scopus)
Colonic Neoplasms
Biomarkers
Neoplasm Metastasis
Vimentin
Cadherins
10 Citations (Scopus)

Glucose-regulated protein 78 mediates the anticancer efficacy of shikonin in hormone-refractory prostate cancer cells

Kuo, L. J., Huang, C. Y., Cheng, W. L., Hung, C. S., Wu, C. T., Lin, F. Y., Chang, Y. J. & Huang, M. T., Jul 29 2015, In : Tumor Biology. 36, 7, p. 5063-5070 8 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Hormones
Small Interfering RNA
Therapeutics
shikonin
6 Citations (Scopus)

Glucose-regulated protein 78 mediates the therapeutic efficacy of 17-DMAG in colon cancer cells

Chang, Y. J., Huang, C. Y., Hung, C. S., Liu, H. H. & Wei, P. L., Jun 11 2015, In : Tumor Biology. 36, 6, p. 4367-4376 10 p.

Research output: Contribution to journalArticle

17-(dimethylaminoethylamino)-17-demethoxygeldanamycin
Colonic Neoplasms
Therapeutics
HT29 Cells
Propidium
12 Citations (Scopus)

GRP78 mediates the therapeutic efficacy of curcumin on colon cancer

Chang, Y-J., Huang, C. Y., Hung, C-S., Chen, W-Y. & Wei, P-L., 2015, In : Tumor Biology. 36, 2, p. 633-641 9 p.

Research output: Contribution to journalArticle

Curcumin
Colonic Neoplasms
HT29 Cells
Therapeutics
In Situ Nick-End Labeling
14 Citations (Scopus)

Novel Link of Anti-apoptotic ATF3 with Pro-apoptotic CTMP in the Ischemic Brain

Huang, C. Y., Chen, J. J., Wu, J. S., Tsai, H. D., Lin, H., Yan, Y. T., Hsu, C-Y., Ho, Y-S. & Lin, T. N., 2015, In : Molecular Neurobiology. 51, 2, p. 543-557 15 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 3
Brain
Proteins
Apoptosis
Activating Transcription Factor 1
13 Citations (Scopus)

Proteomic characterization of annexin l (ANX1) and heat shock protein 27 (HSP27) as biomarkers for invasive hepatocellular carcinoma cells

Wang, R. C., Huang, C. Y., Pan, T. L., Chen, W. Y., Ho, C. T., Liu, T. Z. & Chang, Y. J., Oct 2 2015, In : PLoS One. 10, 10, e0139232.

Research output: Contribution to journalArticle

HSP27 Heat-Shock Proteins
Annexins
Biomarkers
hepatoma
heat shock proteins
2014
10 Citations (Scopus)

15-Deoxy-∆12,14-PGJ2, by Activating Peroxisome Proliferator-Activated Receptor-Gamma, Suppresses p22phox Transcription to Protect Brain Endothelial Cells Against Hypoxia-Induced Apoptosis

Wu, J. S., Tsai, H. D., Huang, C. Y., Chen, J. J. & Lin, T. N., Oct 2 2014, In : Molecular Neurobiology. 50, 1, p. 221-238 18 p.

Research output: Contribution to journalReview article

Cell Hypoxia
PPAR gamma
Endothelial Cells
Apoptosis
Reactive Oxygen Species
2012
66 Citations (Scopus)

Peroxisome proliferator-activated receptor gamma (PPAR-γ) and neurodegenerative disorders

Chen, Y. C., Wu, J. S., Tsai, H. D., Huang, C. Y., Chen, J. J., Sun, G. Y. & Lin, T. N., Jan 1 2012, In : Molecular Neurobiology. 46, 1, p. 114-124 11 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
PPAR gamma
Neurodegenerative Diseases
Parkinson Disease
Alzheimer Disease
26 Citations (Scopus)

Stroke, angiogenesis and phytochemicals

Chen, Y. C., Wu, J. S., Yang, S. T., Huang, C. Y., Chang, C., Sun, G. Y. & Lin, T. N., Jan 1 2012, In : Frontiers in Bioscience - Scholar. 4 S, 2, p. 599-610 12 p.

Research output: Contribution to journalArticle

Phytochemicals
Stroke
Tissue
Nutrients
Brain