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Research Output

  • 1761 Citations
  • 26 h-Index
  • 94 Article
  • 1 Conference contribution
2019
1 Citation (Scopus)
2018
5 Citations (Scopus)

Suppressive activities and mechanisms of ugonin J on vascular smooth muscle cells and balloon angioplasty-induced neointimal hyperplasia

Pan, C. H., Li, P. C., Chien, Y. C., Yeh, W. T., Liaw, C. C., Sheu, M. J. & Wu, C. H., 2018, In : Phytotherapy Research.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Activation of IGF-I survival signaling and its compensative inhibition of the cardiac apoptosis on carotid arteries balloon-injured rat hearts

Hsieh, C. H., Pai, P., Wu, J. P., Ho, T. J., Wu, C. H., Shibu, M. A., Day, C. H., Viswanadha, V. P., Chuang, H. L. & Huang, C. Y., 2017, In : Chinese Journal of Physiology. 60, 3, p. 166-173 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Monoamine oxidase A is highly expressed in classical Hodgkin lymphoma

Li, P. C., Siddiqi, I. N., Mottok, A., Loo, E. Y., Wu, C. H., Cozen, W., Steidl, C. & Shih, J. C., Oct 1 2017, In : Journal of Pathology. 243, 2, p. 220-229 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Pharmacokinetics and tissue distribution of five major triterpenoids after oral administration of Rhizoma Alismatis extract to rats using ultra high-performance liquid chromatography–tandem mass spectrometry

Xu, W., Li, X., Lin, N., Zhang, X., Huang, X., Wu, T., Tai, Y., Chen, S., Wu, C. H., Huang, M. & Wu, S., Nov 30 2017, In : Journal of Pharmaceutical and Biomedical Analysis. 146, p. 314-323 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Toxicological effects of NCKU-21, a phenanthrene derivative, on cell growth and migration of A549 and CL1-5 human lung adenocarcinoma cells

Liao, H. F., Pan, C. H., Chou, P. Y., Chen, Y. F., Wu, T. S., Sheu, M. J. & Wu, C. H., Sep 1 2017, In : PLoS One. 12, 9, e0185021.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2016

Antiobesity and antihyperlipidaemic effects of Yan-Sheng-Yin in animals and humans

Wu, C. H., Pan, C. H., Lee, C. K., Sheu, M. J., Liu, F. C., Wang, G. J. & Wu, C. H., Jun 1 2016, In : Journal of Functional Foods. 24, p. 173-182 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Methyl Protodioscin, a Steroidal Saponin, Inhibits Neointima Formation in Vitro and in Vivo

Chung, Y. L., Pan, C. H., Wang, C. C. N., Hsu, K. C., Sheu, M. J., Chen, H. F. & Wu, C. H., Jun 24 2016, In : Journal of Natural Products. 79, 6, p. 1635-1644 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2015

Anti-restenotic roles of dihydroaustrasulfone alcohol involved in inhibiting PDGF-BB-stimulated proliferation and migration of vascular smooth muscle cells

Li, P. C., Sheu, M. J., Ma, W. F., Pan, C. H., Sheu, J. H. & Wu, C. H., May 1 2015, In : Marine Drugs. 13, 5, p. 3046-3060 15 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

A population-based nested case-control study: The use of 5-alpha-reductase inhibitors and the increased risk of osteoporosis diagnosis in patients with benign prostate hyperplasia

Lin, W. L., Hsieh, Y. W., Lin, C. L., Sung, F. C., Wu, C. H. & Kao, C. H., Apr 1 2015, In : Clinical Endocrinology. 82, 4, p. 503-508 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

K20E, an oxidative-coupling compound of methyl caffeate, exhibits anti-angiogenic activities through down-regulations of VEGF and VEGF receptor-2

Pan, C. H., Lin, W. H., Chien, Y. C., Liu, F. C., Sheu, M. J., Kuo, Y. H. & Wu, C. H., Jan 5 2015, In : Toxicology and Applied Pharmacology. 282, 2, p. 215-226 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014

Deep sea water prevents balloon angioplasty-induced hyperplasia through MMP-2: An in vitro and in vivo study

Li, P. C., Pan, C. H., Sheu, M. J., Wu, C. C., Ma, W. F. & Wu, C. H., May 13 2014, In : PLoS One. 9, 5, e96927.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Effects of garlic oil on interleukin-6 mediated cardiac hypertrophy in hypercholesterol-fed hamsters

Hsieh, Y. L., Pai, P., Ho, T. J., Chung, L. C., Cheng, Y. C., Wu, C. H., Fan, M. J., Day, C. H., Shen, C. Y. & Huang, C. Y., 2014, In : Chinese Journal of Physiology. 57, 6, p. 320-328 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Hydroalcoholic extract of Rhodiola rosea L. (Crassulaceae) and its hydrolysate inhibit melanogenesis in B16F0 cells by regulating the CREB/MITF/tyrosinase pathway

Chiang, H. M., Chien, Y. C., Wu, C. H., Kuo, Y. H., Wu, W. C., Pan, Y. Y., Su, Y. H. & Wen, K. C., Mar 2014, In : Food and Chemical Toxicology. 65, p. 129-139 11 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
11 Citations (Scopus)

NSC746364, a G-quadruplex-stabilizing agent, suppresses cell growth of A549 human lung cancer cells through activation of the ATR/Chk1-dependent pathway

Chung, Y. L., Pan, C. H., Liou, W. H., Sheu, M. J., Lin, W. H., Chen, T. C., Huang, H. S. & Wu, C. H., 2014, In : Journal of Pharmacological Sciences. 124, 1, p. 7-17 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2013

Antihyperlipidemic and antioxidant effects of C-phycocyanin in golden syrian hamsters fed with a hypercholesterolemic diet

Sheu, M. J., Hsieh, Y. Y., Lai, C. H., Chang, C. C. & Wu, C. H., 2013, In : Journal of Traditional and Complementary Medicine. 3, 1, p. 41-47 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: An in Vivo study

Sheu, M. J., Chou, P. Y., Lin, W. H., Pan, C. H., Chien, Y. C., Chung, Y. L., Liu, F. C. & Wu, C. H., Jun 2013, In : Marine Drugs. 11, 6, p. 2183-2202 20 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Demethoxycurcumin, a major active curcuminoid from Curcuma longa, suppresses balloon injury induced vascular smooth muscle cell migration and neointima formation: An in vitro and in vivo study

Sheu, M. J., Lin, H. Y., Yang, Y. H., Chou, C. J., Chien, Y. C., Wu, T. S. & Wu, C. H., Sep 2013, In : Molecular Nutrition and Food Research. 57, 9, p. 1586-1597 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Electrophoretic coating of amphiphilic chitosan colloids on regulating cellular behavior

Wang, Y. J., Lo, T. Y., Wu, C. H. & Liu, D. M., Sep 6 2013, In : Journal of the Royal Society Interface. 10, 86, 0411.

Research output: Contribution to journalArticle

2 Citations (Scopus)
13 Citations (Scopus)

Erratum: Molecular mechanism of green microalgae, Dunaliella salina, involved in attenuating balloon injury-induced neointimal formation (British Journal of Nutrition (2010) 104 (326-335))

Sheu, M. J., Cheng, H. C., Chien, Y. C., Chou, P. Y., Huang, G. J., Chen, J. S., Lin, S. Y. & Wu, C. H., Jun 2013, In : British Journal of Nutrition. 109, 11, p. 2113 1 p.

Research output: Contribution to journalArticle

Gan-Lu-Yin inhibits proliferation and migration of murine WEHI-3 leukemia cells and tumor growth in BALB/C allograft tumor model

Liu, F. C., Pan, C. H., Lai, M. T., Chang, S. J., Chung, J. G. & Wu, C. H., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 684071.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Influence of different particle processing on hypocholesterolemic and antiatherogenic activities of yam (Dioscorea pseudojaponica) in cholesterol-fed rabbit model

Pan, C. H., Tsai, C. H., Liu, F. C., Fan, M. J., Sheu, M. J., Hsieh, W. T. & Wu, C. H., Apr 2013, In : Journal of the Science of Food and Agriculture. 93, 6, p. 1278-1283 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

OSU-A9 inhibits angiogenesis in human umbilical vein endothelial cells via disrupting Akt-NF-κB and MAPK signaling pathways

Omar, H. A., Arafa, E. S. A., Salama, S. A., Arab, H. H., Wu, C. H. & Weng, J. R., Nov 1 2013, In : Toxicology and Applied Pharmacology. 272, 3, p. 616-624 9 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2012

A Chinese herbal formula "Gan-Lu-Yin" suppresses vascular smooth muscle cell migration by inhibiting matrix metalloproteinase-2/9 through the PI3K/AKT and ERK signaling pathways

Chien, Y. C., Sheu, M. J., Wu, C. H., Lin, W. H., Chen, Y. Y., Cheng, P. L. & Cheng, H. C., Aug 24 2012, In : BMC Complementary and Alternative Medicine. 12, 137.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Alteration of the tongue manifestation reflects clinical outcomes of peptic ulcer disease

Wang, H. H., Pan, C. H., Wu, P. P., Luo, S. F., Lin, H. J. & Wu, C. H., Nov 1 2012, In : Journal of Alternative and Complementary Medicine. 18, 11, p. 1038-1044 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Anti-inflammatory effects of Calophyllum inophyllum L. in RAW264.7 cells

Tsai, S. C., Liang, Y. H., Chiang, J. H., Liu, F. C., Lin, W. H., Chang, S. J., Lin, W. Y., Wu, C. H. & Weng, J. R., Sep 2012, In : Oncology Reports. 28, 3, p. 1096-1102 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
49 Citations (Scopus)

Antioxidant and anti-inflammatory properties of Dichondra repens Forst. and its reference compounds

Sheu, M. J., Deng, J. S., Huang, M. H., Liao, J. C., Wu, C. H., Huang, S. S. & Huang, G. J., May 15 2012, In : Food Chemistry. 132, 2, p. 1010-1018 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Computational analysis of novel drugs designed for use as acetylcholinesterase inhibitors and histamine H 3 receptor antagonists for Alzheimer's disease by docking, scoring and de novo evolution

Chen, P. Y., Tsai, C. T., Ou, C. Y., Hsu, W. T., Jhuo, M. D., Wu, C. H., Shih, T. C., Cheng, T. H. & Chung, J. G., Apr 2012, In : Molecular Medicine Reports. 5, 4, p. 1043-1048 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Erratum: Ethanol extracts of fruiting bodies of Antrodia cinnamomea exihibit anti-migration action in human adenocarcinoma CL1-0 cells through the MAPK and PI3K/AKT signaling pathways (Phytomedicine (2012) 19:8 (768-778))

Chen, Y. Y., Liu, F. C., Chou, P. Y., Chien, Y. C., Wu, C. H., Wu, T. S. & Sheu, M. J., Dec 15 2012, In : Phytomedicine. 20, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle

Ethanol extracts of fruiting bodies of Antrodia cinnamomea exhibit anti-migration action in human adenocarcinoma CL1-0 cells through the MAPK and PI3K/AKT signaling pathways

Chen, Y. Y., Chou, P. Y., Chien, Y. C., Wu, C. H., Wu, T. S. & Sheu, M. J., Jun 15 2012, In : Phytomedicine. 19, 8-9, p. 768-778 11 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
39 Citations (Scopus)
16 Citations (Scopus)
18 Citations (Scopus)

Hispolon attenuates balloon-injured neointimal formation and modulates vascular smooth muscle cell migration via AKT and ERK phosphorylation

Chien, Y. C., Huang, G. J., Cheng, H. C., Wu, C. H. & Sheu, M. J., Sep 28 2012, In : Journal of Natural Products. 75, 9, p. 1524-1533 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
40 Citations (Scopus)

Pro-inflammation and pro-fibrosis factors were highly induction in heart tissues of carotid arteries balloon-injured animal model

Hwang, J. M., Wu, C. H., Kuo, W. W., Jong, G. P., Lai, C. H., Tsai, C. H., Tsai, F. J., Chang, M. H., Wu, J. P. & Huang, C. Y., Jul 2012, In : Cell Biochemistry and Function. 30, 5, p. 390-394 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Salvianolic acid B inhibits SDF-1α-stimulated cell proliferation and migration of vascular smooth muscle cells by suppressing CXCR4 receptor

Pan, C. H., Chen, C. W., Sheu, M. J. & Wu, C. H., Jan 2012, In : Vascular Pharmacology. 56, 1-2, p. 98-105 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
37 Citations (Scopus)
2011

Ameliorate effects of li-fu formula on IL-6-mediated cardiac hypertrophy in hamsters fed with a hyper-cholesterol diet

Tzang, B. S., Cheng, Y. C., Wu, C. H., Kuo, W. W., Lin, J. A., Wang, H. F., Tsai, F. J., Tsai, C. H., Huang, C. Y. & Hsu, T. C., 2011, In : Evidence-based Complementary and Alternative Medicine. 2011, 485471.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Antioxidant and anti-inflammatory properties of Cardiospermum halicacabum and its reference compounds ex vivo and in vivo

Huang, M. H., Huang, S. S., Wang, B. S., Wu, C. H., Sheu, M. J., Hou, W. C., Lin, S. S. & Huang, G. J., Jan 27 2011, In : Journal of Ethnopharmacology. 133, 2, p. 743-750 8 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Attenuated cardiac mitochondrial-dependent apoptotic effects by Li-Fu formula in hamsters fed with a hypercholesterol diet

Tzang, B. S., Kuo, W. W., Hsu, T. C., Chain, M. H., Lai, C. H., Wang, W. H., Tsai, F. J., Tsai, C. H., Wu, C. H. & Huang, C. Y., 2011, In : Evidence-based Complementary and Alternative Medicine. 2011, 530345.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Computational analysis of De Novo evolution of Hepatitis C virus NS5B polymerase inhibitors

Chen, P. O. Y., Hsu, W. T., Jhuo, M. D. E., Ou, C. Y., Cheng, T. H., Shih, T. C., Wu, C. H., Wu, R. S. C., Hsia, T. E. C. & Chung, J. G., Mar 2011, In : In Vivo. 25, 2, p. 219-228 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Effects of salvianolic acid B on protein expression in human umbilical vein endothelial cells

Huang, H. C., Chang, T. M., Shi, G. Y., Wu, H. L., Wu, C. H., Su, Y. D., Wang, H. L. & Wen, H. Y., 2011, In : Evidence-based Complementary and Alternative Medicine. 2011, 213050.

Research output: Contribution to journalArticle

8 Citations (Scopus)
25 Citations (Scopus)

Predication the suppressing human oral cancer cell line by curcumin through the research of fas receptor

Chen, P. Y., Wu, Y. C., Cheng, T. H., Shih, T. C., Tsai, C. T., Wu, C. H., Hua, T. Y., Huang, Y. Y., Cheng, C. H. & Fan, M. J., 2011, Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011. p. 209-212 4 p. 6092531

Research output: Chapter in Book/Report/Conference proceedingConference contribution