If you made any changes in Pure these will be visible here soon.

Research Output

  • 1919 Citations
  • 25 h-Index
  • 61 Article
  • 4 Review article
  • 1 Chapter
Filter
Article
2020
1 Citation (Scopus)
2019

Cellular Magnetic Resonance Imaging with Superparamagnetic Iron Oxide: Methods and Applications in Cancer

Hsu, F. T., Sun, R. & Hsieh, C. L., Jan 1 2019, In : SPIN.

Research output: Contribution to journalArticle

Discovery and mechanisms of host defense to oncogenesis: targeting the β-defensin-1 peptide as a natural tumor inhibitor

Sun, C. Q., Arnold, R. S., Hsieh, C. L., Dorin, J. R., Lian, F., Li, Z. & Petros, J. A., Jun 3 2019, In : Cancer Biology and Therapy. 20, 6, p. 774-786 13 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
4 Citations (Scopus)

KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC

Wang, H. J., Pochampalli, M., Wang, L. Y., Zou, J. X., Li, P. S., Hsu, S. C., Wang, B. J., Huang, S. H., Yang, P., Yang, J. C., Chu, C. Y., Hsieh, C. L., Sung, S. Y., Li, C. F., Tepper, C. G., Ann, D. K., Gao, A. C., Evans, C. P., Izumiya, Y., Chuu, C. P. & 3 others, Wang, W. C., Chen, H. W. & Kung, H. J., Jan 3 2019, In : Oncogene. 38, 1, p. 17-32

Research output: Contribution to journalArticle

12 Citations (Scopus)
2018

Amentoflavone Induces Apoptosis and Inhibits NF-ĸB-modulated Anti-apoptotic Signaling in Glioblastoma Cells

Yen, T-H., Hsieh, C-L., Liu, T-T., Huang, C-S., Chen, Y-C., Chuang, Y-C., Lin, S-S. & Hsu, F-T., Feb 25 2018, In : In Vivo. 32, 2, p. 279-285 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

MRI tracking of polyethylene glycol-coated superparamagnetic iron oxide-labelled placenta-derived mesenchymal stem cells toward glioblastoma stem-like cells in a mouse model

Hsu, F. T., Wei, Z. H., Hsuan, Y. C. Y., Lin, W., Su, Y. C., Liao, C. H. & Hsieh, C. L., Jan 1 2018, (Accepted/In press) In : Artificial Cells, Nanomedicine and Biotechnology.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

Amentoflavone enhances sorafenib-induced apoptosis through extrinsic and intrinsic pathways in sorafenib-resistant hepatocellular carcinoma SK-hep1 cells in vitro

Chen, W. L., Hsieh, C. L., Chen, J. H., Huang, C. S., Chen, W. T., Kuo, Y. C., Chen, C. Y. & Hsu, F. T., 2017, In : Oncology Letters. 14, 3, p. 3229-3234 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Reactive oxygen species-mediated switching expression of MMP-3 in stromal fibroblasts and cancer cells during prostate cancer progression

Hsieh, C. L., Liu, C. M., Chen, H. A., Yang, S. T., Shigemura, K., Kitagawa, K., Yamamichi, F., Fujisawa, M., Liu, Y. R., Lee, W. H., Chen, K. C., Shen, C. N., Lin, C. C., Chung, L. W. K. & Sung, S. Y., Dec 1 2017, In : Scientific Reports. 7, 1, 9065.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2016
5 Citations (Scopus)

Erlotinib-Conjugated Iron Oxide Nanoparticles as a Smart Cancer-Targeted Theranostic Probe for MRI

Ali, A. A. A., Hsu, F. T., Hsieh, C. L., Shiau, C. Y., Chiang, C. H., Wei, Z. H., Chen, C. Y. & Huang, H. S., Nov 11 2016, In : Scientific Reports. 6, 36650.

Research output: Contribution to journalArticle

18 Citations (Scopus)

TGF-β and IL-21 cooperatively stimulate activated CD8+ T cells to differentiate into Tc17 cells

Chen, H. W., Tsai, J. P., Yao, T. Y., Hsieh, C. L., Chen, I. H. & Liu, S. J., Jun 1 2016, In : Immunology Letters. 174, p. 23-27 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2014

ADAR1 deaminase contributes to scheduled skeletal myogenesis progression via stage-specific functions

Hsieh, C. L., Liu, H., Huang, Y., Kang, L., Chen, H. W., Chen, Y. T., Wee, Y. R., Chen, S. J. & Tan, B. C. M., 2014, In : Cell Death and Differentiation. 21, 5, p. 707-719 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Targeting L1 cell adhesion molecule expression using liposomeencapsulated siRNA suppresses prostate cancer bone metastasis and growth

Sung, S. Y., Wu, I. H., Chuang, P. H., Petros, J. A., Wu, H. C., Zeng, H. J., Huang, W. C., Chung, L. W. K. & Hsieh, C. L., 2014, In : Oncotarget. 5, 20, p. 9911-9929 19 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The role of DAB2IP in androgen receptor activation during prostate cancer progression

Wu, K., Liu, J., Tseng, S. F., Gore, C., Ning, Z., Sharifi, N., Fazli, L., Gleave, M., Kapur, P., Xiao, G., Sun, X., Oz, O. K., Min, W., Alexandrakis, G., Yang, C. R., Hsieh, C. L., Wu, H. C., He, D., Xie, D. & Hsieh, J. T., Apr 10 2014, In : Oncogene. 33, 15, p. 1954-1963 10 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2013

A functional genomic approach reveals the transcriptional role of EDD in the expression and function of angiogenesis regulator ACVRL1

Chen, H. W., Yang, C. C., Hsieh, C. L., Liu, H., Lee, S. C. & Tan, B. C. M., Dec 2013, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1829, 12, p. 1309-1319 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

In Vivo Targeting of ADAM9 Gene Expression Using Lentivirus-Delivered shRNA Suppresses Prostate Cancer Growth by Regulating REG4 Dependent Cell Cycle Progression

Liu, C. M., Hsieh, C. L., He, Y. C., Lo, S. J., Liang, J. A., Hsieh, T. F., Josson, S., Chung, L. W. K., Hung, M. C. & Sung, S. Y., Jan 16 2013, In : PLoS One. 8, 1, e53795.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Loss of let-7 microRNA upregulates IL-6 in bone marrow-derived mesenchymal stem cells triggering a reactive stromal response to prostate cancer.

Sung, S. Y., Liao, C. H., Wu, H. P., Hsiao, W. C., Wu, I. H., Jinpu, Yu, Lin, S. H. & Hsieh, C. L., 2013, In : PLoS One. 8, 8, e71637.

Research output: Contribution to journalArticle

48 Citations (Scopus)
2012

Epigeneitc silencing of ribosomal RNA genes by Mybbp1a

Tan, B. C. M., Yang, C. C., Hsieh, C. L., Chou, Y. H., Zhong, C. Z., Yung, B. Y. M. & Liu, H., 2012, In : Journal of Biomedical Science. 19, 1, 57.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Epigenetic silencing of myogenic gene program by Myb-binding protein 1a suppresses myogenesis

Yang, C. C., Liu, H., Chen, S. L., Wang, T. H., Hsieh, C. L., Huang, Y., Chen, S. J., Chen, H. C., Yung, B. Y. M. & Tan, B. C. M., Apr 4 2012, In : EMBO Journal. 31, 7, p. 1739-1751 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
22 Citations (Scopus)
2011

Increased expression of IL-21 reduces tumor growth by modulating the status of tumor-infiltrated lymphocytes

Hsieh, C. L., Hsu, S. C., Shen, C. R., Chen, M. Y., Liu, S. J., Chong, P. & Chen, H. W., 2011, In : Immunobiology. 216, 4, p. 491-496 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Inhibition of ADAM9 expression induces epithelial phenotypic alterations and sensitizes human prostate cancer cells to radiation and chemotherapy

Josson, S., Anderson, C. S., Sung, S. Y., Johnstone, P. A. S., Kubo, H., Hsieh, C. L., Arnold, R., Gururajan, M., Yates, C. & Chung, L. W. K., Feb 15 2011, In : Prostate. 71, 3, p. 232-240 9 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

WDHD1 modulates the post-transcriptional step of the centromeric silencing pathway

Hsieh, C. L., Lin, C. L., Liu, H., Chang, Y. J., Shih, C. J., Zhong, C. Z., Lee, S. C. & Tan, B. C. M., May 2011, In : Nucleic Acids Research. 39, 10, p. 4048-4062 15 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2010

A novel targeting modality for renal cell carcinoma: Human osteocalcin promoter-mediated gene therapy synergistically induced by vitamin C and vitamin D3

Johnson, N. A., Chen, B. H., Sung, S. Y., Liao, C. H., Hsiao, W. C., W.K. Chung, L. & Hsieh, C. L., Nov 2010, In : Journal of Gene Medicine. 12, 11, p. 892-903 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

IL-6-transfected tumor cells modulate the status of CD8+ and CD4+ T cells to control tumor growth

Hsieh, C. L., Liu, S. J., Shen, C. R., Chen, M. Y., Hsu, S. C., Tsai, J. P., Li, Y. S., Yang, C. J., Chong, P. & Chen, H. W., Jun 2010, In : Immunobiology. 215, 6, p. 486-491 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Targeting L1 cell adhesion molecule using lentivirus-mediated short hairpin RNA interference reverses aggressiveness of oral squamous cell carcinoma

Hung, S. C., Wu, I. H., Hsue, S. S., Liao, C. H., Wang, H. C., Chuang, P. H., Sung, S. Y. & Hsieh, C. L., Dec 6 2010, In : Molecular Pharmaceutics. 7, 6, p. 2312-2323 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2009

Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment

Arnold, R. S., Sun, C. Q., Richards, J. C., Grigoriev, G., Coleman, I. M., Nelson, P. S., Hsieh, C. L., Lee, J. K., Xu, Z., Rogatko, A., Osunkoya, A. O., Zayzafoon, M., Chung, L. & Petros, J. A., Jan 1 2009, In : Prostate. 69, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Visualizing Human Prostate Cancer Cells in Mouse Skeleton Using Bioconjugated Near-infrared Fluorescent Quantum Dots

Shi, C., Zhu, Y., Xie, Z., Qian, W., Hsieh, C. L., Nie, S., Su, Y., Zhau, H. E. & Chung, L. W. K., Aug 2009, In : Urology. 74, 2, p. 446-451 6 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2008

Coevolution of prostate cancer and bone stroma in three-dimensional coculture: Implications for cancer growth and metastasis

Sung, S. Y., Hsieh, C. L., Law, A., Zhau, H. E., Pathak, S., Multani, A. S., Lim, S., Coleman, I. M., Wu, L. C., Figg, W. D., Dahut, W. L., Nelson, P., Lee, J. K., Amin, M. B., Lyles, R., Johnstone, P. A. J., Marshall, F. F. & Chung, L. W. K., Dec 1 2008, In : Cancer Research. 68, 23, p. 9996-10003 8 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)

In-vivo xenograft murine human uveal melanoma model develops hepatic micrometastases

Yang, H., Fang, G., Huang, X., Yu, J., Hsieh, C. L. & Grossniklaus, H. E., Apr 2008, In : Melanoma Research. 18, 2, p. 95-103 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Petroleum ether extract of Cnidium monnieri ameliorated scopolamine-induced amnesia through adrenal gland-mediated mechanism in male rats

Wu, C. R., Lin, L. W., Hsieh, C. L., Wang, W. H., Lin, Y. T. & Hsieh, M. T., May 22 2008, In : Journal of Ethnopharmacology. 117, 3, p. 403-407 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2007

Induction of a distinct CD8 Tnc17 subset by transforming growth factor-β and interleukin-6

Liu, S. J., Tsai, J. P., Shen, C. R., Sher, Y. P., Hsieh, C. L., Yeh, Y. C., Chou, A. H., Chang, S. R., Hsiao, K. N., Yu, F. W. & Chen, H. W., Aug 1 2007, In : Journal of Leukocyte Biology. 82, 2, p. 354-360 7 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model

Hsieh, C. L., Xie, Z., Yu, J., Martin, W. D., Datta, M. W., Wu, G. J. & Chung, L. W. K., May 15 2007, In : Prostate. 67, 7, p. 685-691 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2006

Identification of α-enolase as an autoantigen in lung cancer: Its overexpression is associated with clinical outcomes

Chang, G. C., Liu, K. J., Hsieh, C. L., Hu, T. S., Charoenfuprasert, S., Liu, H. K., Luh, K. T., Hsu, L. H., Wu, C. W., Ting, C. C., Chen, C. Y., Chen, K. C., Yang, T. Y., Chou, T. Y., Wang, W. H., Whang-Peng, J. & Shih, N. Y., Oct 1 2006, In : Clinical Cancer Research. 12, 19, p. 5746-5754 9 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)

IGF-I secretion by prostate carcinoma cells does not alter tumor-bone cell interactions in vitro or in vivo

Rubin, J., Fan, X., Rahnert, J., Sen, B., Hsieh, C. L., Murphy, T. C., Nanes, M. S., Horton, L. G., Beamer, W. G. & Rosen, C. J., Jun 1 2006, In : Prostate. 66, 8, p. 789-800 12 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Stromal-epithelial interaction in prostate cancer progression

Chung, L. W. K., Huang, W. C., Sung, S. Y., Wu, D., Odero-Marah, V., Nomura, T., Shigemura, K., Miyagi, T., Seo, S., Shi, C., Molitierno, J., Elmore, J., Anderson, C., Isotani, S., Edlund, M., Hsieh, C. L., Wang, R., Shehata, B. & Zhau, H. E., 2006, In : Clinical Genitourinary Cancer. 5, 2, p. 162-170 9 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

β2-microglobulin is a signaling and growth-promoting factor for human prostate cancer bone metastasis

Huang, W. C., Wu, D., Xie, Z., Zhau, H. E., Nomura, T., Zayzafoon, M., Pohl, J., Hsieh, C. L., Weitzmann, M. N., Farach-Carson, M. C. & Chung, L. W. K., Sep 15 2006, In : Cancer Research. 66, 18, p. 9108-9116 9 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)
2005

A luciferase transgenic mouse model: Visualization of prostate development and its androgen responsiveness in live animals

Hsieh, C. L., Xie, Z., Liu, Z. Y., Green, J. E., Martin, W. D., Datta, M. W., Yeung, F., Pan, D. & Chung, L. W. K., Oct 2005, In : Journal of Molecular Endocrinology. 35, 2, p. 293-304 12 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Amplification and overexpression of prosaposin in prostate cancer

Koochekpour, S., Zhang, Y., Beroukhim, R., Hsieh, C. L., Hofer, M. D., Zhau, H. E., Hiraiwa, M., Pattan, D. Y., Ware, J. L., Luftig, R. B., Sandhoff, K., Sawyers, C. L., Pienta, K. J., Rubin, M. A., Vessella, R. L., Sellers, W. R. & Sartor, O., Dec 2005, In : Genes Chromosomes and Cancer. 44, 4, p. 351-364 14 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Analysis of host versus tumor interaction in cancer patients: Opposing role of transforming growth factor-β1 and interleukin-6 in the development of in situ tumor immunity

Tsai, J. P., Chen, H. W., Cheng, M. L., Liu, H. K., Lee, Y. P., Hsieh, C. L., Luh, K. T., Wu, C. W., Hsu, L. H., Chao, T. Y., Wang, W. H., Chang, C. M. & Ting, C. C., Nov 15 2005, In : Immunobiology. 210, 9, p. 661-671 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Cotargeting tumor and tumor endothelium effectively inhibits the growth of human prostate cancer in adenovirus-mediated antiangiogenesis and oncolysis combination therapy

Jin, F., Xie, Z., Kuo, C. J., Chung, L. W. K. & Hsieh, C. L., Mar 2005, In : Cancer Gene Therapy. 12, 3, p. 257-267 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Effects of tobacco prevention education program on adolescents' knowledge of and attitude toward smoking

Tsai, W. C., Kung, P. T., Hu, H. Y., Ho, C. S., Lin, D. J., Hsieh, C. L., Teng, Y. L., Chen, C. H., Wu, J. F., Chiang, C. Y. & Yang, T. J., Dec 2005, In : Mid-Taiwan Journal of Medicine. 10, 4, p. 171-180 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Morin sulphates/glucuronides enhance macrophage function in microgravity culture system

Hsieh, C. L., Chao, P. D. L. & Fang, S. H., Sep 2005, In : European Journal of Clinical Investigation. 35, 9, p. 591-596 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Targeting ECM-integrin interaction with liposome-encapsulated small interfering RNAs inhibits the growth of human prostate cancer in a bone xenograft imaging model

Bisanz, K., Yu, J., Edlund, M., Spohn, B., Hung, M. C., Chung, L. W. K. & Hsieh, C. L., Oct 2005, In : Molecular Therapy. 12, 4, p. 634-643 10 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)
2004

Cotargeting tumor and stroma in a novel chimeric tumor model involving the growth of both human prostate cancer and bone stromal cells

Hsieh, C. L., Gardner, T. A., Miao, L., Balian, G. & Chung, L. W. K., Feb 2004, In : Cancer Gene Therapy. 11, 2, p. 148-155 8 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Osthole improves aspects of spatial performance in ovariectomized rats

Hsieh, M. T., Hsieh, C. L., Wang, W. H., Chen, C. S., Lin, C. J. & Wu, C. R., 2004, In : American Journal of Chinese Medicine. 32, 1, p. 11-20 10 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2003

Caspase activation during phorbol ester-induced apoptosis requires ROCK-dependent myosin-mediated contraction

Lai, J. M., Hsieh, C. L. & Chang, Z. F., Sep 1 2003, In : Journal of Cell Science. 116, 17, p. 3491-3501 11 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Differential gene expression of scopolamine-treated rat hippocampus-application of cDNA microarray technology

Hsieh, M. T., Hsieh, C. L., Lin, L. W., Wu, C. R. & Huang, G. S., Jul 11 2003, In : Life Sciences. 73, 8, p. 1007-1016 10 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

New targets for therapy in prostate cancer: Modulation of stromal-epithelial interactions

Chung, L. W. K., Hsieh, C. L., Law, A., Sung, S. Y., Gardner, T. A., Egawa, M., Matsubara, S. & Zhau, H. E., Nov 2003, In : Urology. 62, 5 SUPPL. 1, p. 44-54 11 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)