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Research Output

  • 685 Citations
  • 12 h-Index
  • 27 Article
  • 1 Chapter
  • 1 Comment/debate
  • 1 Review article
2019

Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., Jan 1 2019, In : Biomaterials. 190-191, p. 1-10 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Transcriptomic and Proteomic Profiling of Human Mesenchymal Stem Cell Derived from Umbilical Cord in the Study of Preterm Birth

Chien, C. W., Lo, Y. S., Wu, H. Y., Hsuan, Y., Lin, C. K., Chen, Y. J., Lin, W. & Han, C. L., Jan 1 2019, (Accepted/In press) In : Proteomics - Clinical Applications. 1900024.

Research output: Contribution to journalArticle

2018
12 Citations (Scopus)

Chemotherapy Immunophenoprofiles in Non-Small-Cell Lung Cancer by Personalized Membrane Proteomics

Putri, D. U., Feng, P. H., Hsu, Y. H., Lee, K. Y., Jiang, F. W., Kuo, L. W., Chen, Y. J. & Han, C. L., Jan 1 2018, (Accepted/In press) In : Proteomics - Clinical Applications.

Research output: Contribution to journalArticle

3 Citations (Scopus)

ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells

Chang, C. W., Chen, Y. S., Tsay, Y. G., Han, C. L., Chen, Y. J., Yang, C. C., Hung, K. F., Lin, C. H., Huang, T. Y., Kao, S. Y., Lee, T. C. & Lo, J. F., Feb 1 2018, In : Cell Death and Disease. 9, 2, 194.

Research output: Contribution to journalArticle

12 Citations (Scopus)

S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: The role of RELB

Feng, P. H., Yu, C. T., Chen, K. Y., Luo, C. S., Wu, S. M., Liu, C. Y., Kuo, L. W., Chan, Y. F., Chen, T. T., Chang, C. C., Lee, C. N., Chuang, H. C., Lin, C. F., Han, C. L., Lee, W. H. & Lee, K. Y., Jan 26 2018, In : Oncotarget. 9, 7, p. 7631-7643 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Subcellular Proteome Landscape of Human Embryonic Stem Cells Revealed Missing Membrane Proteins

Weldemariam, M. M., Han, C-L., Shekari, F., Kitata, R. B., Chuang, C-Y., Hsu, W-T., Kuo, H-C., Choong, W-K., Sung, T-Y., He, F-C., Chung, M. C. M., Salekdeh, G. H. & Chen, Y-J., Dec 7 2018, In : Journal of Proteome Research. 17, 12, p. 4138-4151 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Surface markers of human embryonic stem cells: a meta analysis of membrane proteomics reports

Shekari, F., Han, C. L., Lee, J., Mirzaei, M., Gupta, V., Haynes, P. A., Lee, B., Baharvand, H., Chen, Y. J. & Hosseini Salekdeh, G., Nov 2 2018, In : Expert Review of Proteomics. 15, 11, p. 911-922 12 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

β-Amyloid Induces Pathology-Related Patterns of Tau Hyperphosphorylation at Synaptic Terminals

Wu, H-Y., Kuo, P-C., Wang, Y-T., Lin, H-T., Roe, A. D., Wang, B. Y., Han, C-L., Hyman, B. T., Chen, Y-J. & Tai, H-C., Sep 1 2018, In : Journal of Neuropathology and Experimental Neurology. 77, 9, p. 814-826 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2017

Identification of Potential Plasma Biomarkers for Nonalcoholic Fatty Liver Disease by Integrating Transcriptomics and Proteomics in Laying Hens

Tsai, M. T., Chen, Y. J., Chen, C. Y., Tsai, M. H., Han, C. L., Chen, Y. J., Mersmann, H. J. & Ding, S. T., Mar 1 2017, In : The Journal of nutrition. 147, 3, p. 293-303 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Membrane proteomics of impaired energetics and cytoskeletal disorganization in elderly diet-induced diabetic mice

Hung, C. L., Pan, S. H., Han, C. L., Chang, C. W., Hsu, Y. L., Su, C. H., Shih, S. C., Lai, Y. J., Chiau, J. S. C., Yeh, H. I., Liu, C. Y., Lee, H. C. & Lam, C. S. P., Oct 6 2017, In : Journal of Proteome Research. 16, 10, p. 3504-3513 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Proteome analysis of human embryonic stem cells organelles

Shekari, F., Nezari, H., Larijani, M. R., Han, C. L., Baharvand, H., Chen, Y. J. & Salekdeh, G. H., Jun 6 2017, In : Journal of Proteomics. 162, p. 108-118 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016

Streptococcal pyrogenic exotoxin B inhibits apoptotic cell clearance by macrophages through protein S cleavage

Chen, C. L., Wu, Y. Y., Lin, C. F., Kuo, C. F., Han, C. L., Wang, S., Chuang, W. J., Chen, C. Y., Wu, J. J., Tsai, P. J., Liu, C. C. & Lin, Y. S., May 16 2016, In : Scientific Reports. 6, 26026.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2015

Mitochondrial translocation of EGFR regulates mitochondria dynamics and promotes metastasis in NSCLC

Che, T. F., Lin, C. W., Wu, Y. Y., Chen, Y. J., Han, C. L., Chang, Y. L., Wu, C. T., Hsiao, T. H., Hong, T. M. & Yang, P. C., 2015, In : Oncotarget. 6, 35, p. 37349-37366 18 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2014

Distinct subpopulations of head and neck cancer cells with different levels of intracellular reactive oxygen species exhibit diverse stemness, proliferation, and chemosensitivity

Chang, C. W., Chen, Y. S., Chou, S. H., Han, C. L., Chen, Y. J., Yang, C. C., Huang, C. Y. & Lo, J. F., Nov 1 2014, In : Cancer Research. 74, 21, p. 6291-6305 15 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Quantitative proteomics analysis highlights the role of redox hemostasis and energy metabolism in human embryonic stem cell differentiation to neural cells

Fathi, A., Hatami, M., Vakilian, H., Han, C. L., Chen, Y. J., Baharvand, H. & Salekdeh, G. H., Apr 14 2014, In : Journal of Proteomics. 101, p. 1-16 16 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2013

A chemically functionalized magnetic nanoplatform for rapid and specific biomolecular recognition and separation

Lin, P. C., Yu, C. C., Wu, H. T., Lu, Y. W., Han, C. L., Su, A. K., Chen, Y. J. & Lin, C. C., Jan 14 2013, In : Biomacromolecules. 14, 1, p. 160-168 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

An iTRAQ proteomic study reveals an association between diet-induced enhanced fatty acid metabolism and the development of glucose intolerance in prediabetic mice

Ho, J. H., Lee, O. K., Fu, Y. J., Shih, H. T., Tseng, C. Y., Chung, C. C., Han, C. L. & Chen, Y. J., 2013, In : Journal of Proteome Research. 12, 3, p. 1120-1133 14 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

BAD-lectins: Boronic acid-decorated lectins with enhanced binding affinity for the selective enrichment of glycoproteins

Lu, Y. W., Chien, C. W., Lin, P. C., Huang, L. D., Chen, C. Y., Wu, S. W., Han, C. L., Khoo, K. H., Lin, C. C. & Chen, Y. J., 2013, In : Analytical Chemistry. 85, 17, p. 8268-8276 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Identification of downstream components of ubiquitin-conjugating enzyme PHOSPHATE2 by quantitative membrane proteomics in Arabidopsis roots

Huang, T. K., Han, C. L., Lin, S. I., Chen, Y. J., Tsai, Y. C., Chen, Y. R., Chen, J. W., Lin, W. Y., Chen, P. M., Liu, T. Y., Chen, Y. S., Sun, C. M. & Chiou, T. J., Oct 2013, In : Plant Cell. 25, 10, p. 4044-4060 17 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

Prioritization of cancer marker candidates based on the immunohistochemistry staining images deposited in the Human Protein Atlas

Chiang, S. C., Han, C. L., Yu, K. H., Chen, Y. J. & Wu, K. P., Nov 26 2013, In : PLoS One. 8, 11, e81079.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2012

Membrane proteomics for the opportunity of cancer biomarker and drug target discovery

Han, C. L., Chien, C. W., Chen, P. M., Chen, I. H. & Chen, Y. J., Jan 1 2012, Systems Biology: Applications in Cancer-Related Research. World Scientific Publishing Co., p. 259-285 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

An informatics-assisted label-free approach for personalized tissue membrane proteomics: Case study on colorectal cancer

Han, C. L., Chen, J. S., Chan, E. C., Wu, C. P., Yu, K. H., Chen, K. T., Tsou, C. C., Tsai, C. F., Chien, C. W., Kuo, Y. B., Lin, P. Y., Yu, J. S., Hsueh, C., Chen, M. C., Chan, C. C., Chang, Y. S. & Chen, Y. J., Apr 2011, In : Molecular and Cellular Proteomics. 10, 4

Research output: Contribution to journalArticle

47 Citations (Scopus)

Identification of SEC61β and its autoantibody as biomarkers for colorectal cancer

Fan, C. W., Chan, C. C., Chen, K. T., Twu, J., Huang, Y. S., Han, C. L., Chen, Y. J., Yu, J. S., Chang, Y. S., Kuo, Y. B. & Chan, E. C., May 12 2011, In : Clinica Chimica Acta. 412, 11-12, p. 887-893 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2010

Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry

Chen, J. S., Chen, K. T., Fan, C. W., Han, C. L., Chen, Y. J., Yu, J. S., Chang, Y. S., Chien, C. W., Wu, C. P., Hung, R. P. & Chan, E. C., Jul 2010, In : FEBS Journal. 277, 14, p. 3028-3038 11 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Temporal proteomics profiling of lipid rafts in CCR6-activated T cells reveals the integration of actin cytoskeleton dynamics

Lin, S. L., Chien, C. W., Han, C. L., Chen, E. S. W., Kao, S. H., Chen, Y. J. & Liao, F., Jan 4 2010, In : Journal of Proteome Research. 9, 1, p. 283-297 15 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2008

A multiplexed quantitative strategy for membrane proteomics: Opportunities for mining therapeutic targets for autosomal dominant polycystic kidney disease

Han, C. L., Chien, C. W., Chen, W. C., Chen, Y. R., Wu, C. P., Li, H. & Chen, Y. J., Oct 2008, In : Molecular and Cellular Proteomics. 7, 10, p. 1983-1997 15 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)

Proteomic profiles of bronchoalveolar lavage fluid from patients with ventilator-associated pneumonia by gel-assisted digestion and 2-D-LC/MS/MS

Lu, Y. T., Han, C. L., Wu, C. L., Yu, T. M., Chien, C. W., Liu, C. L. & Chen, Y. J., Sep 2008, In : Proteomics - Clinical Applications. 2, 9, p. 1208-1222 15 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2006

Multi-Q: A fully automated tool for multiplexed protein quantitation

Lin, W. T., Hung, W. N., Yian, Y. H., Wu, K. P., Han, C. L., Chen, Y. R., Chen, Y. J., Sung, T. Y. & Hsu, W. L., Sep 2006, In : Journal of Proteome Research. 5, 9, p. 2328-2338 11 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)