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Research Output 2004 2019

  • 654 Citations
  • 10 h-Index
  • 16 Article
  • 1 Comment/debate
2019

Crystal Structures of the C-Terminally Truncated Endoglucanase Cel9Q from Clostridium thermocellum Complexed with Cellodextrins and Tris

Jeng, W. Y., Liu, C. I., Lu, T. J., Lin, H. J., Wang, N. C. & Wang, A. H. J., Jan 18 2019, In : ChemBioChem. 20, 2, p. 295-307 13 p.

Research output: Contribution to journalArticle

Open Access
Clostridium thermocellum
Cellobiose
Clostridium
Cellulase
Crystal structure
2018
1 Citation (Scopus)

Characterization of chicken-derived single chain antibody fragments against venom of Naja naja atra

Lee, C. H., Leu, S. J., Lee, Y. C., Liu, C. I., Lin, L. T., Mwale, P. F., Chiang, J. R., Tsai, B. Y., Chen, C. C., Hung, C. S. & Yang, Y. Y., Oct 1 2018, In : Toxins. 10, 10, 383.

Research output: Contribution to journalArticle

Cobra Venoms
Elapidae
Single-Chain Antibodies
Immunoglobulin Fragments
Venoms

Correction: Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1 [Oncotarget, 7 (2016) (43629-43653)] Doi: 10.18632/oncotarget.9660

Yin, S. Y., Efferth, T., Jian, F. Y., Chen, Y. H., Liu, C. I., Wang, A. H. J., Chen, Y. R., Hsiao, P. W. & Yang, N. S., Aug 14 2018, In : Oncotarget. 9, 63, p. 32271 1 p.

Research output: Contribution to journalComment/debate

Scientific Misconduct
Ethics Committees
Taiwan
Breast Neoplasms
shikonin
2016
10 Citations (Scopus)

Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1

Yin, S. Y., Efferth, T., Jian, F. Y., Chen, Y. H., Liu, C. I., Wang, A. H. J., Chen, Y. R., Hsiao, P. W. & Yang, N. S., 2016, In : Oncotarget. 7, 28, p. 43629-43653 25 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoproteins
Breast Neoplasms
Neoplasms
Cell Death
Pharmacology
2014
29 Citations (Scopus)

Crowning proteins: Modulating the protein surface properties using crown ethers

Lee, C. C., Maestre-Reyna, M., Hsu, K. C., Wang, H. C., Liu, C. I., Jeng, W. Y., Lin, L. L., Wood, R., Chou, C. C., Yang, J. M. & Wang, A. H. J., Nov 24 2014, In : Angewandte Chemie - International Edition. 53, 48, p. 13054-13058 5 p.

Research output: Contribution to journalArticle

Crown Ethers
Crown ethers
Surface properties
Proteins
Membrane Proteins
9 Citations (Scopus)

Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis

Yang, H. C., Chuang, J. Y., Jeng, W. Y., Liu, C. I., Wang, A. H. J., Lu, P. J., Chang, W. C. & Hung, J. J., Dec 16 2014, In : Nucleic Acids Research. 42, 22, p. 13573-13587 15 p.

Research output: Contribution to journalArticle

Mitosis
Phosphorylation
DNA
Peptides
Cell Cycle
23 Citations (Scopus)

Structural insights into the catalytic mechanism of human squalene synthase

Liu, C. I., Jeng, W. Y., Chang, W. J., Shih, M. F., Ko, T. P. & Wang, A. H. J., Feb 2014, In : Acta Crystallographica Section D: Biological Crystallography. 70, 2, p. 231-241 11 p.

Research output: Contribution to journalArticle

Farnesyl-Diphosphate Farnesyltransferase
Niacinamide
Biosynthetic Pathways
Phosphates
Squalene
2012
25 Citations (Scopus)

Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase

Liu, C. I., Jeng, W. Y., Chang, W. J., Ko, T. P. & Wang, A. H. J., May 25 2012, In : Journal of Biological Chemistry. 287, 22, p. 18750-18757 8 p.

Research output: Contribution to journalArticle

Farnesyl-Diphosphate Farnesyltransferase
Oxidative stress
Sterols
Enzymes
Metabolites
21 Citations (Scopus)

High-resolution structures of Neotermes koshunensis β-glucosidase mutants provide insights into the catalytic mechanism and the synthesis of glucoconjugates

Jeng, W. Y., Wang, N. C., Lin, C. T., Chang, W. J., Liu, C. I. & Wang, A. H. J., Jul 2012, In : Acta Crystallographica Section D: Biological Crystallography. 68, 7, p. 829-838 10 p.

Research output: Contribution to journalArticle

Glucosidases
HEPES
Opipramol
Glucose
Oligosaccharides
2011
106 Citations (Scopus)

Structural and functional analysis of three β-glucosidases from bacterium Clostridium cellulovorans, fungus Trichoderma reesei and termite Neotermes koshunensis

Jeng, W. Y., Wang, N. C., Lin, M. H., Lin, C. T., Liaw, Y. C., Chang, W. J., Liu, C. I., Liang, P. H. & Wang, A. H. J., Jan 2011, In : Journal of Structural Biology. 173, 1, p. 46-56 11 p.

Research output: Contribution to journalArticle

Clostridium cellulovorans
Glucosidases
Isoptera
Trichoderma
Fungi
2010
42 Citations (Scopus)

Mechanism of action and inhibition of dehydrosqualene synthase

Lin, F. Y., Liu, C. I., Liu, Y. L., Zhang, Y., Wang, K., Jeng, W. Y., Ko, T. P., Cao, R., Wang, A. H. J. & Oldfield, E., Dec 14 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 50, p. 21337-21342 6 p.

Research output: Contribution to journalArticle

Diphosphates
Terpenes
Alkenes
Sterols
Carotenoids
16 Citations (Scopus)

Structures of human MST3 kinase in complex with adenine, ADP and Mn 2+

Ko, T. P., Jeng, W. Y., Liu, C. I., Lai, M. D., Wu, C. L., Chang, W. J., Shr, H. L., Lu, T. J. & Wang, A. H. J., 2010, In : Acta Crystallographica Section D: Biological Crystallography. 66, 2, p. 145-154 10 p.

Research output: Contribution to journalArticle

Adenine
Adenosine Diphosphate
Catalytic Domain
Phosphotransferases
Ligands
2009
56 Citations (Scopus)

Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: In vitro, in vivo, and crystallographic results

Song, Y., Liu, C. I., Lin, F. Y., Joo, H. N., Hensler, M., Liu, Y. L., Jeng, W. Y., Low, J., Liu, G. Y., Nizet, V., Wang, A. H. J. & Oldfield, E., Jul 9 2009, In : Journal of Medicinal Chemistry. 52, 13, p. 3869-3880 12 p.

Research output: Contribution to journalArticle

Virulence Factors
Staphylococcus aureus
Carotenoids
Gold
Inhibitory Concentration 50
2008
265 Citations (Scopus)

A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence

Liu, C. I., Liu, G. Y., Song, Y., Yin, F., Hensler, M. E., Jeng, W. Y., Nizet, V., Wang, A. H. J. & Oldfield, E., Mar 7 2008, In : Science. 319, 5868, p. 1391-1394 4 p.

Research output: Contribution to journalArticle

Anticholesteremic Agents
Virulence
Staphylococcus aureus
Farnesyl-Diphosphate Farnesyltransferase
Cholesterol
36 Citations (Scopus)

Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in staphylococcus epidermidis

Jeng, W. Y., Ko, T. P., Liu, C. I., Guo, R. T., Liu, C. L., Shr, H. L. & Wang, A. H. J., Mar 2008, In : Nucleic Acids Research. 36, 5, p. 1567-1577 11 p.

Research output: Contribution to journalArticle

Iron-Dextran Complex
Staphylococcus epidermidis
Biofilms
DNA
Repressor Proteins
2005
5 Citations (Scopus)

LrrA, a novel leucine-rich repeat protein involved in cytoskeleton remodeling, is required for multicellular morphogenesis in Dictyostelium discoideum

Liu, C. I., Cheng, T. L., Chen, S. Z., Huang, Y. C. & Chang, W. T., Sep 1 2005, In : Developmental Biology. 285, 1, p. 238-251 14 p.

Research output: Contribution to journalArticle

Dictyostelium
Cytoskeleton
Morphogenesis
Actins
Fluorescence
2004
10 Citations (Scopus)

Disruption of the peroxisomal citrate synthase CshA affects cell growth and multicellular development in Dictyostelium discoideum

Huang, Y. C., Chen, Y. H., Lo, S. R., Liu, C. I., Wang, C. W. & Chang, W. T., Jul 2004, In : Molecular Microbiology. 53, 1, p. 81-91 11 p.

Research output: Contribution to journalArticle

Citrate (si)-Synthase
Dictyostelium
Growth and Development
Citric Acid
Peroxisomes