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Research Output

2019

A novel 2-aminobenzimidazole-based compound Jzu 17 exhibits anti-angiogenesis effects by targeting VEGFR-2 signalling

Lien, J. C., Chung, C. L., Huang, T. F., Chang, T. C., Chen, K. C., Gao, G. Y., Hsu, M. J. & Huang, S. W., Oct 1 2019, In : British Journal of Pharmacology. 176, 20, p. 4034-4049 16 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2 Citations (Scopus)

Endothelin-1 Induces Mesothelial Mesenchymal Transition and Correlates with Pleural Fibrosis in Tuberculous Pleural Effusions

Wu, Z-H., Tsai, J-H., Hsieh, C-Y., Chen, W-L. & Chung, C-L., Mar 29 2019, In : Journal of Clinical Medicine. 8, 4, 426.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Analysis of Titin in Red and White Muscles: Crucial Role on Muscle Contractions Using a Fish Model

Wu, M. P., Chang, N. C., Chung, C. L., Chiu, W. C., Hsu, C. C., Chen, H. M., Sheu, J. R., Jayakumar, T., Chou, D. S. & Fong, T. H., Nov 18 2018, In : BioMed Research International. 2018, p. 5816875 11 p., 5816875.

Research output: Contribution to journalArticle

2 Citations (Scopus)

An Antithrombotic Strategy by Targeting Phospholipase D in Human Platelets

Lu, W. J., Chung, C. L., Chen, R. J., Huang, L. T., Lien, L. M., Chang, C. C., Lin, K. H. & Sheu, J. R., Nov 14 2018, In : Journal of Clinical Medicine. 7, 11

Research output: Contribution to journalArticle

Decreased risk of pneumonia in stroke patients receiving acupuncture: A nationwide matched-pair retrospective cohort study

Chang, C. C., Chen, T. L., Lin, C. S., Chung, C. L., Yeh, C. C., Hu, C. J., Lane, H. L., Liao, C. C. & Shih, C. C., May 1 2018, In : PLoS One. 13, 5, e0196094.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
6 Citations (Scopus)
4 Citations (Scopus)

Lipoteichoic acid upregulates plasminogen activator inhibitor-1 expression in parapneumonic effusions

Lee, K. L., Chen, W. L., Chen, R. J., Lai, K. S. & Chung, C. L., Jan 1 2018, In : Respirology. 23, 1, p. 89-95 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
4 Citations (Scopus)

Novel therapeutic agent against platelet activation in vitro and arterial thrombosis in vivo by morin hydrate

Hsia, C. W., Wu, M. P., Velusamy, M., Hsia, C. H., Chou, D. S., Tsai, C. L., Hsu, C. Y., Jayakumar, T., Chung, C. L. & Sheu, J. R., Aug 13 2018, In : International Journal of Molecular Sciences. 19, 8, 2386.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Structure-antiplatelet activity relationships of novel ruthenium (ii) complexes: Investigation of its molecular targets

Hsia, C. H., Jayakumar, T., Sheu, J. R., Tsao, S. Y., Velusamy, M., Hsia, C. W., Chou, D. S., Chang, C. C., Chung, C. L., Khamrang, T. & Lin, K. C., Feb 22 2018, In : Molecules. 23, 2, 477.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Brain metastases in patients with non-small cell lung cancer: the role of mutated-EGFRs with an exon 19 deletion or L858R point mutation in cancer cell dissemination

Hsiao, S-H., Chou, Y-T., Lin, S-E., Hsu, R-C., Chung, C-L., Kao, Y-R., Liu, H. E. & Wu, C-W., Aug 8 2017, In : Oncotarget. 8, 32, p. 53405-53418 14 p.

Research output: Contribution to journalArticle

Diabetes risks and outcomes in chronic obstructive pulmonary disease patients: Two nationwide population-based retrospective cohort studies

Lin, C. S., Liu, C. C., Yeh, C. C., Chang, Y. C., Chung, C. L., Lane, H. L., Shih, C. C., Chen, T. L. & Liao, C. C., 2017, In : PLoS One. 12, 8, p. e0181815

Research output: Contribution to journalArticle

12 Citations (Scopus)

Risk of stroke and post-stroke adverse events in patients with exacerbations of chronic obstructive pulmonary disease

Lin, C-S., Shih, C. C., Yeh, C. C., Hu, C-J., Chung, C-L., Chen, T-L. & Liao, C-C., Jan 1 2017, In : PLoS One. 12, 1, e0169429.

Research output: Contribution to journalArticle

10 Citations (Scopus)
25 Citations (Scopus)
2016

Novel synthetic benzimidazole-derived oligosaccharide, M3BIM, prevents ex vivo platelet aggregation and in vivo thromboembolism

Yen, T. L., Wu, M. P., Chung, C. L., Yang, W. B., Jayakumar, T., Geraldine, P., Chou, C. M., Chang, C. Y., Lu, W-J. & Sheu, J. R., Feb 17 2016, In : Journal of Biomedical Science. 23, 1, 26.

Research output: Contribution to journalArticle

3 Citations (Scopus)
5 Citations (Scopus)
2015

Adverse outcomes after non-chest surgeries in patients with pulmonary tuberculosis: A nationwide study

Ke, C. C., Lin, C-S., Yeh, C. C., Chung, C-L., Hung, C. J., Liao, C-C., Chen, T-L. & Hozbor, D. F., Jul 14 2015, In : PLoS One. 10, 7, e0133064.

Research output: Contribution to journalArticle

2 Citations (Scopus)
3 Citations (Scopus)
10 Citations (Scopus)
17 Citations (Scopus)

Proper Diagnostic Differentiation of Atypical Adenomatous Hyperplasia and Pulmonary Adenocarcinoma

Lai, K. S., Lin, S-E., Zeng, M-S., Lee, K-L., Hsiao, S-H. & Chung, C-L., Aug 1 2015, In : 胸腔醫學. 30, 4, p. 224-231 8 p.

Research output: Contribution to journalArticle

VEGF correlates with inflammation and fibrosis in tuberculous pleural effusion

Bien, M. Y., Wu, M-P., Chen, W. L. & Chung, C. L., 2015, In : Scientific World Journal. 2015, 417124.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2014

Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption

Hsiao, C. J., Hsiao, G., Chen, W. L., Wang, S. W., Chiang, C. P., Liu, L. Y., Guh, J. H., Li, Z-H. & Chung, C. L., Apr 25 2014, In : Journal of Natural Products. 77, 4, p. 758-765 8 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
13 Citations (Scopus)

Multidrug resistance protein 4 (MRP4/ABCC4) regulates thrombus formation in vitro and in vivo

Lien, L. M., Chen, Z. C., Chung, C. L., Yen, T. L., Chiu, H. C., Chou, D. S., Huang, S. Y., Sheu, J. R., Lu, W-J. & Lin, K. H., Aug 15 2014, In : European Journal of Pharmacology. 737, p. 159-167 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Pulmonary air crescent sign

Lee, K. L., Liang, H. H., Chung, C. L., Hsiao, S. H. & Shih, C. H., 2014, In : JAMA Surgery. 149, 1, p. 97-98 2 p.

Research output: Contribution to journalShort survey

1 Citation (Scopus)
2013

Brazilin isolated from Caesalpinia sappan L. acts as a novel collagen receptor agonist in human platelets

Chang, Y., Huang, S. K. H., Lu, W. J., Chung, C. L., Chen, W. L., Lu, S. H., Lin, K. H. & Sheu, J. R., Jan 25 2013, In : Journal of Biomedical Science. p. 4 1 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Clinical Importance of Angiogenic Cytokines, Fibrinolytic Activity and Effusion Size in Parapneumonic Effusions

Chung, C. L., Hsiao, S. H., Hsiao, G., Sheu, J. R., Chen, W. L. & Chang, S. C., Jan 7 2013, In : PLoS One. 8, 1, e53169.

Research output: Contribution to journalArticle

8 Citations (Scopus)
8 Citations (Scopus)

ENdothelin-1 in inflammatory and malignant pleural effusions

Chung, C-L., Chen, W-L., Hsiao, S-H. & Hsiao, G., Oct 1 2013, In : Chest. 144, 4_MeetingAbstracts, p. 516A-516A

Research output: Contribution to journalMeeting Abstract

Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo

Lin, K. H., Kuo, J. R., Lu, W-J., Chung, C. L., Chou, D. S., Huang, S. Y., Lee, H. C. & Sheu, J. R., May 15 2013, In : Biochemical Pharmacology. 85, 10, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
File
7 Downloads (Pure)

Identification of subgroup patients with stage IIIB/IV non-small cell lung cancer at higher risk for brain metastases

Hsiao, S. H., Chung, C. L., Chou, Y. T., Lee, H. L., Lin, S. E. & Liu, H. E., Nov 2013, In : Lung Cancer. 82, 2, p. 319-323 5 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
31 Citations (Scopus)

Mechanisms of andrographolide-induced platelet apoptosis in human platelets: Regulatory roles of the extrinsic apoptotic pathway

Lien, L-M., Su, C. C., Hsu, W. H., Lu, W-J., Chung, C-L., Yen, T. L., Chiu, H. C., Sheu, J-R. & Lin, K. H., 2013, In : Phytotherapy Research. 27, 11, p. 1671-1677 7 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Suitability of computed tomography-guided biopsy specimens for subtyping and genotyping of non-small-cell lung cancer

Hsiao, S. H., Chung, C. L., Lee, C-M., Chen, W. Y., Chou, Y. T., Wu, Z. H., Chen, Y. C. & Lin, S. E., Nov 2013, In : Clinical Lung Cancer. 14, 6, p. 719-725 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2012
8 Citations (Scopus)

Pycnidione, a fungus-derived agent, induces cell cycle arrest and apoptosis in A549 human lung cancer cells

Hsiao, C. J., Hsiao, S. H., Chen, W. L., Guh, J. H., Hsiao, G., Chan, Y. J., Li, Z-H. & Chung, C. L., Apr 15 2012, In : Chemico-Biological Interactions. 197, 1, p. 23-30 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation

Lee, W. R., Chung, C. L., Hsiao, C. J., Chou, Y. C., Hsueh, P. J., Yang, P. C., Jan, J. S., Cheng, Y. W. & Hsiao, G., Feb 15 2012, In : Phytomedicine. 19, 3-4, p. 270-277 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2011

Angiogenic Cytokines And Fibrinolytic Activity In Parapneumonic Effusions: A103. NOVEL INSIGHTS FOR PATIENT SAFETY IN BRONCHOSCOPY AND PLEURAL DISEASE

Chung, C-L., Hsiao, S. H., Chen, W-L. & Chang, S. C., 2011, Am J Respir Crit Care Med. American Thoracic Society, p. A2360-A2360 (American Thoracic Society International Conference Abstracts).

Research output: Chapter in Book/Report/Conference proceedingChapter

Hypertonicity-enhanced TNF-α release from activated human monocytic THP-1 cells requires ERK activation

Chou, Y. C., Sheu, J. R., Chung, C. L., Hsiao, C. J., Hsueh, P. J. & Hsiao, G., Apr 2011, In : Biochimica et Biophysica Acta - General Subjects. 1810, 4, p. 475-484 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2010
24 Citations (Scopus)