Projects per year
Personal profile
Awards
- 2011 Regular Postdoctoral Fellow of Academia Sinica
- 2009 Regular Postdoctoral Fellow of Academia Sinica
- 2008 Excellent Thesis Award, 4th Yung Shin Tien Te Lee Medical and Pharmaceutical Science and Technology Awards
- 2007 Dr. Chien-Tien Hsu Excellent Oral Presentation Award,16th International Symposium on Recent Advances in Cellular and Molecular Biology
- 2005 Student Exchange Program in Kobe University. Interchange Association (Japan).
Education
- Ph. D. (2008) The Institute of Basic Medical Science of National Cheng-Kung University,.
- Master (2003) Department Of Pharmacology, National Cheng-Kung University,
- B.A. (2001) School of Pharmacy, Taipei Medical University,
Experience
- 2012 Project Assistant professor, The Institute of Basic Medical Science of National Cheng-Kung University
- 2008 Postdoctoral fellow, Institute of Molecular Biology, Academia Sinica
URL
Research Interests
- Neurodegenerative disease
- Neuromolecular biology
- Post-translational modification
Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
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Colorectal Neoplasms
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Autophagy
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Frontotemporal Lobar Degeneration
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Epithelial-Mesenchymal Transition
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2019
探究漸凍人運動神經退化性疾病中E3泛素連接酶Znf179調控病態性 TDP-43引起的神經絲蛋白病變之機制探究
8/1/18 → 7/31/19
Project: h - Other (Funded by TMU)
探究腦指蛋白Znf179的E3泛素連接酉每活性以及對TDP-43病理蛋白的影響(3/3)
8/1/17 → 7/31/18
Project: b - Ministry of Science and Technology
探究腦指蛋白Znf179的E3泛素連接酉每活性以及對TDP-43病理蛋白的影響(2/3)
8/1/16 → 7/31/17
Project: b - Ministry of Science and Technology
Characterize the E3 Ligase Activity of Znf179 and Its Effect on the Proteinopathies of TDP-43 Protein
8/1/15 → 7/31/16
Project: b - Ministry of Science and Technology
片段化TDP-43蛋白在缺血性腦中風之神經發炎物質NF-κB 訊息傳遞路徑中所扮演的角色
6/1/15 → 5/31/16
Project: o - Taipei Medical University Hospital › Research
Research Output 2007 2019
Potential therapeutic effect of curcumin, a natural mTOR inhibitor, in tuberous sclerosis complex
Kuo, C. J., Huang, C. C., Chou, S. Y., Lo, Y. C., Kao, T. J., Huang, N. K., Lin, C., Lin, H. C., Lin, H. C. & Lee, Y. C., Feb 15 2019, In : Phytomedicine. 54, p. 132-139 8 p.Research output: Contribution to journal › Article
Tuberous Sclerosis
Curcumin
Therapeutic Uses
Memory Disorders
Lipids
DNA primase polypeptide 1 (PRIM1) involves in estrogen-induced breast cancer formation through activation of the G2/M cell cycle checkpoint
Lee, W-H., Chen, L-C., Lee, C-J., Huang, C-C., Ho, Y-S., Yang, P-S., Ho, C-T., Chang, H-L., Lin, I-H., Chang, H-W., Liu, Y-R., Wu, C-H. & Tu, S-H., Aug 11 2018, In : International Journal of Cancer.Research output: Contribution to journal › Article
DNA Primase
G2 Phase Cell Cycle Checkpoints
Estrogens
Breast Neoplasms
Peptides
Ephexin1 is required for Eph-Mediated limb trajectory of spinal motor axons
Chang, C. J., Chang, M. Y., Chou, S. Y., Huang, C. C., Chuang, J. Y., Hsu, T. I., Chang, H. F., Wu, Y. H., Wu, C. C., Morales, D., Kania, A. & Kao, T. J., Feb 21 2018, In : Journal of Neuroscience. 38, 8, p. 2043-2056 14 p.Research output: Contribution to journal › Article
Axons
Extremities
Ephrins
Growth Cones
Motor Neurons
Erratum to: Znf179 induces differentiation and growth arrest of human primary glioblastoma multiforme in a p53-dependent cell cycle pathway (Scientific Reports, (2017), 7, 1, (4787), 10.1038/s41598-017-05305-0)
Lee, K. H., Chen, C. L., Lee, Y. C., Kao, T. J., Chen, K. Y., Fang, C. Y., Chang, W. C., Chiang, Y. H. & Huang, C. C., Dec 1 2018, In : Scientific Reports. 8, 1, 13375.Research output: Contribution to journal › Comment/debate
Glioblastoma
Cell Cycle
Growth
Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, Y-C., Huang, W-C., Lin, J-H., Kao, T-J., Lin, H-C., Lee, K-H., Lin, H-C., Shen, C-K. J., Chang, W-C. & Huang, C-C., Nov 8 2018, In : Journal of Biomedical Science. 25, 1, p. 76 1 p.Research output: Contribution to journal › Article
Ubiquitin-Protein Ligases
Pathology
Amyotrophic Lateral Sclerosis
Frontotemporal Lobar Degeneration
Proteins
Press / Media
U.S. Patent and Trademark Office Awards Patent for Deep Magnetic Field Generating Apparatus
4/27/16
1 item of media coverage
Press/Media: Press / Media