• 685 Citations
  • 14 h-Index
20072020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 685 Citations
  • 14 h-Index
  • 33 Article
2019

A critical period for the development of schizophrenia-like pathology by aberrant postnatal neurogenesis

Sheu, J. R., Hsieh, C. Y., Jayakumar, T., Tseng, M. F., Lee, H. N., Huang, S. W., Manubolu, M. & Yang, C. H., Jan 1 2019, In : Frontiers in Neuroscience. 13, JUN, 635.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Endothelin-1 Induces Mesothelial Mesenchymal Transition and Correlates with Pleural Fibrosis in Tuberculous Pleural Effusions

Wu, Z-H., Tsai, J-H., Hsieh, C-Y., Chen, W-L. & Chung, C-L., Mar 29 2019, In : Journal of Clinical Medicine. 8, 4, 426.

Research output: Contribution to journalArticle

HDAC6 dysfunction contributes to impaired maturation of adult neurogenesis in vivo: vital role on functional recovery after ischemic stroke

Sheu, J-R., Hsieh, C-Y., Jayakumar, T., Lin, G-Y., Lee, H-N., Huang, S-W. & Yang, C-H., Apr 18 2019, In : Journal of Biomedical Science. 26, 1, 27.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Intravenous thrombolysis administration 3–4.5 h after acute ischemic stroke: A retrospective, multicenter study

Chen, Y. W., Sung, S. F., Chen, C. H., Tang, S. C., Tsai, L. K., Lin, H. J., Huang, H. Y., Po, H. L., Sun, Y., Chen, P. L., Chan, L., Wei, C. Y., Lee, J. T., Hsieh, C. Y., Lin, Y. Y., Yeh, S. J., Lien, L. M. & Jeng, J. S., Jan 1 2019, In : Frontiers in Neurology. 10, OCT, 1038.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
Open Access
1 Citation (Scopus)
2018

CME-1, a novel polysaccharide, suppresses iNOS expression in lipopolysaccharide-stimulated macrophages through ceramide-initiated protein phosphatase 2A activation

Sheu, J. R., Chen, Z. C., Hsu, M. J., Wang, S. H., Jung, K. W., Wu, W. F., Pan, S. H., Teng, R. D., Yang, C. H. & Hsieh, C. Y., Feb 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 2, p. 999-1013 15 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Hinokitiol inhibits migration of A549 lung cancer cells via suppression of MMPs and induction of antioxidant enzymes and apoptosis

Jayakumar, T., Liu, C. H., Wu, G. Y., Lee, T. Y., Manubolu, M., Hsieh, C. Y., Yang, C. H. & Sheu, J. R., Mar 22 2018, In : International Journal of Molecular Sciences. 19, 4, 939.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Inhibitory effect of PDGF-BB and serum-stimulated responses in vascular smooth muscle cell proliferation by hinokitiol via up-regulation of p21 and p53

Li, J-Y., Liu, C-P., Shiao, W-C., Jayakumar, T., Li, Y-S., Chang, N-C., Huang, S-Y. & Hsieh, C-Y., Jan 1 2018, In : Archives of Medical Science. 14, 3, p. 579-587 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
4 Citations (Scopus)
2017

A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice

Sheu, J. R., Chen, Z. C., Jayakumar, T., Chou, D. S., Yen, T. L., Lee, H. N., Pan, S. H., Hsia, C. H., Yang, C. H. & Hsieh, C. Y., Feb 6 2017, In : Scientific Reports. 7, 42277.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Antiplatelet activity of a newly synthesized novel ruthenium (II): A potential role for Akt/JNK signaling

Khamrang, T., Hung, K. C., Hsia, C. H., Hsieh, C. Y., Velusamy, M., Jayakumar, T. & Sheu, J. R., May 1 2017, In : International Journal of Molecular Sciences. 18, 5, 916.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016
34 Citations (Scopus)

Major vault protein regulates cell growth/survival signaling through oxidative modifications

Das, D., Wang, Y. H., Hsieh, C. Y. & Suzuki, Y. J., Jan 1 2016, In : Cellular Signalling. 28, 1, p. 12-18 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Prevention of arterial thrombosis by nobiletin: In vitro and in vivo studies

Lu, W-J., Lin, K. C., Liu, C. P., Lin, C. Y., Wu, H. C., Chou, D. S., Geraldine, P., Huang, S. Y., Hsieh, C. Y. & Sheu, J. R., Feb 1 2016, In : Journal of Nutritional Biochemistry. 28, p. 1-8 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2015

Antiproliferative activity of hinokitiol, a tropolone derivative, is mediated via the inductions of p-JNK and p-PLCγ1 signaling in PDGF-BB-Stimulated vascular smooth muscle cells

Yang, P. S., Wang, M. J., Jayakumar, T., Chou, D. S., Ko, C. Y., Hsu, M. J. & Hsieh, C. Y., May 1 2015, In : Molecules. 20, 5, p. 8198-8212 15 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2014

Andrographolide induces vascular smooth muscle cell apoptosis through a SHP-1-PP2A-p38MAPK-p53 cascade

Chen, Y. Y., Hsieh, C. Y., Jayakumar, T., Lin, K. H., Chou, D. S., Lu, W-J., Hsu, M. J. & Sheu, J. R., Jul 10 2014, In : Scientific Reports. 4, 5651.

Research output: Contribution to journalArticle

23 Citations (Scopus)
16 Citations (Scopus)
9 Citations (Scopus)
2013
22 Citations (Scopus)

A novel antithrombotic effect of sulforaphane via activation of platelet adenylate cyclase: Ex vivo and in vivo studies

Jayakumar, T., Chen, W. F., Lu, W-J., Chou, D. S., Hsiao, G., Hsu, C-Y., Sheu, J. R. & Hsieh, C. Y., Jun 2013, In : Journal of Nutritional Biochemistry. 24, 6, p. 1086-1095 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
90 Citations (Scopus)

IL-22 activates oxidant signaling in pulmonary vascular smooth muscle cells

Bansal, G., Das, D., Hsieh, C. Y., Wang, Y. H., Gilmore, B. A., Wong, C. M. & Suzuki, Y. J., Dec 2013, In : Cellular Signalling. 25, 12, p. 2727-2733 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Novel bioactivity of ellagic acid in inhibiting human platelet activation

Chang, Y., Chen, W. F., Lin, K. H., Hsieh, C. Y., Chou, D. S., Lin, L. J., Sheu, J. R. & Chang, C. C., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 595128.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2012
56 Citations (Scopus)
2011

Andrographolide enhances nuclear factor-κB subunit p65 Ser 536 dephosphorylation through activation of protein phosphatase 2A in vascular smooth muscle cells

Hsieh, C. Y., Hsu, M. J., Hsiao, G., Wang, Y. H., Huang, C. W., Chen, S. W., Jayakumar, T., Chiu, P. T., Chiu, Y. H. & Sheu, J. R., Feb 25 2011, In : Journal of Biological Chemistry. 286, 8, p. 5942-5955 14 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)

Chondroprotective role of sesamol by inhibiting MMPs expression via retaining NF-κB signaling in activated SW1353 cells

Lu, Y. C., Jayakumar, T., Duann, Y. F., Chou, Y. C., Hsieh, C. Y., Yu, S. Y., Sheu, J. R. & Hsiao, G., May 11 2011, In : Journal of Agricultural and Food Chemistry. 59, 9, p. 4969-4978 10 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Platonin inhibited PDGF-BB-induced proliferation of rat vascular smooth muscle cells via JNK1/2-dependent signaling

Chang, Y., Uen, Y. H., Chen, C. C., Lin, S-C., Tseng, S. Y., Wang, Y. H., Sheu, J. R. & Hsieh, C. Y., Nov 2011, In : Acta Pharmacologica Sinica. 32, 11, p. 1337-1344 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2010
10 Citations (Scopus)

Inhibitory effect of PMC, a potent hydrophilic α-tocopherol derivative, on vascular smooth muscle cell proliferation: The pivotal role of PKC-α translocation

Chang, C. C., Lee, J. J., Chiang, C-W., Jayakumar, T., Hsiao, G., Hsieh, C. Y. & Sheu, J. R., Aug 2010, In : Pharmaceutical Biology. 48, 8, p. 938-946 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2009

Inhibitory effects of ketamine on lipopolysaccharide-induced microglial activation

Sheu, J. R., Chang, Y., Lee, J. J., Hsieh, C. Y., Hsiao, G. & Chou, D. S., 2009, In : Mediators of Inflammation. 2009, 705379.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Neuroprotective mechanisms of puerarin in middle cerebral artery occlusion-induced brain infarction in rats

Chang, Y., Hsieh, C. Y., Peng, Z. A., Yen, T. L., Hsiao, G., Chou, D. S., Chen, C. M. & Sheu, J. R., 2009, In : Journal of Biomedical Science. 16, 1, 9.

Research output: Contribution to journalArticle

89 Citations (Scopus)
2007

Baicalein induction of hydroxyl radical formation via 12-lipoxygenase in human platelets: An ESR study

Chou, D. S., Lee, J. J., Hsiao, G., Hsieh, C. Y., Tsai, Y. J., Chen, T-F. & Sheu, J. R., Feb 7 2007, In : Journal of Agricultural and Food Chemistry. 55, 3, p. 649-655 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)