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Research Output

  • 1688 Citations
  • 24 h-Index
  • 51 Article
  • 2 Comment/debate
2020
Open Access
1 Citation (Scopus)
4 Citations (Scopus)
2019
Open Access
34 Citations (Scopus)

Dietary flavonoids luteolin and quercetin inhibit migration and invasion of squamous carcinoma through reduction of src/stat3/s100a7 signaling

Fan, J. J., Hsu, W. H., Lee, K. H., Chen, K. C., Lin, C. W., Lee, Y. L. A., Ko, T. P., Lee, L. T., Lee, M. T., Chang, M. S. & Cheng, C. H., Nov 2019, In : Antioxidants. 8, 11, 557.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Metastatic colorectal cancer rewrites metabolic program through a Glut3-YAP-dependent signaling circuit

Kuo, C. C., Ling, H. H., Chiang, M. C., Chung, C. H., Lee, W. Y., Chu, C. Y., Wu, Y. C., Chen, C. H., Lai, Y. W., Tsai, I. L., Cheng, C. H. & Lin, C. W., Jan 1 2019, In : Theranostics. 9, 9, p. 2526-2540 15 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
6 Citations (Scopus)

Reduction in MnSOD promotes the migration and invasion of squamous carcinoma cells

Fan, J. J., Hsu, W. H., Hung, H. H., Zhang, W. J., A Lee, Y. L., Chen, K. C., Chu, C. Y., Ko, T. P., Lee, M. T., Lin, C. W. & Cheng, C. H., May 2019, In : International Journal of Oncology. 54, 5, p. 1639-1650 12 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

The antipsychotic chlorpromazine suppresses YAP signaling, stemness properties, and drug resistance in breast cancer cells

Yang, C. E., Lee, W. Y., Cheng, H. W., Chung, C. H., Mi, F. L. & Lin, C. W., Apr 1 2019, In : Chemico-Biological Interactions. 302, p. 28-35 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells

Chen, P. C., Lee, W. Y., Ling, H. H., Cheng, C. H., Chen, K. C. & Lin, C. W., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Flavonoids Luteolin and Quercetin Inhibit RPS19 and contributes to metastasis of cancer cells through c-Myc reduction

Chen, K. C., Hsu, W. H., Ho, J. Y., Lin, C. W., Chu, C. Y., Kandaswami, C. C., Lee, M. T. & Cheng, C. H., Jan 1 2018, (Accepted/In press) In : Journal of Food and Drug Analysis.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2017
24 Citations (Scopus)

Development of a new type of multifunctional fucoidan-based nanoparticles for anticancer drug delivery

Lu, K. Y., Li, R., Hsu, C. H., Lin, C. W., Chou, S. C., Tsai, M. L. & Mi, F. L., Jun 1 2017, In : Carbohydrate Polymers. 165, p. 410-420 11 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Dietary flavonoids, luteolin and quercetin, inhibit invasion of cervical cancer by reduction of UBE2S through epithelial-mesenchymal transition signaling

Lin, T. H., Hsu, W. H., Tsai, P. H., Huang, Y. T., Lin, C. W., Chen, K. C., Tsai, I. H., Kandaswami, C. C., Huang, C. J., Chang, G. D., Lee, M. T. & Cheng, C. H., Apr 1 2017, In : Food and Function. 8, 4, p. 1558-1568 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Elevation of YAP promotes the epithelial-mesenchymal transition and tumor aggressiveness in colorectal cancer

Ling, H. H., Kuo, C. C., Lin, B. X., Huang, Y. H. & Lin, C. W., Jan 1 2017, In : Experimental Cell Research. 350, 1, p. 218-225 8 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
12 Citations (Scopus)

Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ

Lee, W. Y., Chen, P. C., Wu, W. S., Wu, H. C., Lan, C. H., Huang, Y. H., Cheng, C. H., Chen, K. C. & Lin, C. W., 2017, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Podocalyxin-like protein 1 regulates TAZ signaling and stemness properties in colon cancer

Lee, W. Y., Kuo, C. C., Lin, B. X., Cheng, C. H., Chen, K. C. & Lin, C. W., Oct 1 2017, In : International Journal of Molecular Sciences. 18, 10, 2047.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The CHAC1-inhibited Notch3 pathway is involved in temozolomide-induced glioma cytotoxicity

Chen, P. H., Shen, W. L., Shih, C-M., Ho, K. H., Cheng, C-H., Lin, C-W., Lee, C-C., Liu, A. J. & Chen, K-C., Apr 1 2017, In : Neuropharmacology. 116, p. 300-314 15 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The microRNA-302b-inhibited insulin-like growth factor-binding protein 2 signaling pathway induces glioma cell apoptosis by targeting nuclear factor IA

Lee, C. C., Chen, P. H., Ho, K. H., Shih, C. M., Cheng, C. H., Lin, C. W., Cheng, K. T., Liu, A. J. & Chen, K. C., Mar 1 2017, In : PLoS One. 12, 3, e0173890.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2016

The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling involves in temozolomide-Induced glioma cell apoptotic death

Chen, P. H., Cheng, C-H., Shih, C-M., Ho, K. H., Lin, C-W., Lee, C-C., Liu, A. J., Chang, C-K. & Chen, K-C., Nov 1 2016, In : PLoS One. 11, 11, e0167096.

Research output: Contribution to journalArticle

21 Citations (Scopus)

The miR-204-3p-targeted IGFBP2 pathway is involved in xanthohumol-induced glioma cell apoptotic death

Chen, P. H., Chang, C. K., Shih, C. M., Cheng, C. H., Lin, C. W., Lee, C. C., Liu, A. J., Ho, K. H. & Chen, K. C., Nov 1 2016, In : Neuropharmacology. 110, p. 362-375 14 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2015

An anti-EpCAM antibody EpAb2-6 for the treatment of colon cancer

Liao, M. Y., Lai, J. K., Kuo, M. Y. P., Lu, R. M., Lin, C. W., Cheng, P. C., Liang, K. H. & Wu, H. C., 2015, In : Oncotarget. 6, 28, p. 24947-24968 22 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
40 Citations (Scopus)

CD44-specific nanoparticles for redox-triggered reactive oxygen species production and doxorubicin release

Lin, C-W., Lu, K. Y., Wang, S. Y., Sung, H. W. & Mi, F-L., Oct 19 2015, (Accepted/In press) In : Acta Biomaterialia.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Effect of Grape Seed Proanthocyanidin-Gelatin Colloidal Complexes on Stability and in Vitro Digestion of Fish Oil Emulsions

Su, Y. R., Tsai, Y. C., Hsu, C. H., Chao, A. C., Lin, C. W., Tsai, M. L. & Mi, F. L., Nov 17 2015, In : Journal of Agricultural and Food Chemistry. 63, 46, p. 10200-10208 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1

Lee, W. Y., Lee, W. T., Cheng, C. H., Chen, K. C., Chou, C. M., Chung, C. H., Sun, M. S., Cheng, H. W., Ho, M. N. & Lin, C. W., 2015, In : Oncotarget. 6, 29, p. 27580-27595 16 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

RPS12 increases the invasiveness in cervical cancer activated by c-Myc and inhibited by the dietary flavonoids luteolin and quercetin

Lin, C. W., Lai, G. M., Chen, K. C., Lin, T. H., Fan, J. J., Hsu, R. L., Chou, C. M., Lin, C. M., Kandaswami, C. C., Lee, M. T. & Cheng, C. H., Dec 1 2015, In : Journal of Functional Foods. 19, p. 236-247 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2014

Delivery of berberine using chitosan/fucoidan-taurine conjugate nanoparticles for treatment of defective intestinal epithelial tight junction barrier

Wu, S. J., Don, T. M., Lin, C-W. & Mi, F-L., Nov 24 2014, In : Marine Drugs. 12, 11, p. 5677-5697 21 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

FRET-based dual-emission and pH-responsive nanocarriers for enhanced delivery of protein across intestinal epithelial cell barrier

Lu, K. Y., Lin, C. W., Hsu, C. H., Ho, Y. C., Chuang, E-T., Sung, H. W. & Mi, F. L., Oct 22 2014, In : ACS Applied Materials and Interfaces. 6, 20, p. 18275-18289 15 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Induction of ROS-independent JNK-activation-mediated apoptosis by a novel coumarin-derivative, DMAC, in human colon cancer cells

Lin, M. H., Cheng, C. H., Chen, K. C., Lee, W. T., Wang, Y. F., Xiao, C. Q. & Lin, C. W., Jul 25 2014, In : Chemico-Biological Interactions. 218, p. 42-49 8 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

MicroRNA-302b-inhibited E2F3 transcription factor is related to all trans retinoic acid-induced glioma cell apoptosis

Chen, P. H., Shih, C. M., Chang, W. C., Cheng, C. H., Lin, C. W., Ho, K. H., Su, P. C. & Chen, K. C., 2014, In : Journal of Neurochemistry. 131, 6, p. 731-742 12 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
25 Citations (Scopus)

Podocalyxin-like 1 promotes invadopodia formation and metastasis through activation of Rac1/Cdc42/cortactin signaling in breast cancer cells

Lin, C. W., Sun, M. S., Liao, M. Y., Chung, C. H., Chi, Y. H., Chiou, L. T., Yu, J., Lou, K. L. & Wu, H. C., Nov 1 2014, In : Carcinogenesis. 35, 11, p. 2425-2435 11 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Tea catechins-cross-linked methylcellulose active films for inhibition of light irradiation and lipid peroxidation induced β-carotene degradation

Yu, S. H., Tsai, M. L., Lin, B. X., Lin, C. W. & Mi, F. L., Nov 4 2014, In : Food Hydrocolloids. 44, p. 491-505 15 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2013

CHC promotes tumor growth and angiogenesis through regulation of HIF-1α and VEGF signaling

Tung, K. H., Lin, C. W., Kuo, C. C., Li, L. T., Kuo, Y. H., Lin, C. W. & Wu, H. C., Apr 30 2013, In : Cancer Letters. 331, 1, p. 58-67 10 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2012

Epithelial cell adhesion molecule regulates tumor initiation and tumorigenesis via activating reprogramming factors and epithelial-mesenchymal transition gene expression in colon cancer

Lin, C. W., Liao, M. Y., Lin, W. W., Wang, Y. P., Lu, T. Y. & Wu, H. C., Nov 16 2012, In : Journal of Biological Chemistry. 287, 47, p. 39449-39459 11 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)
2010
77 Citations (Scopus)
71 Citations (Scopus)
2009
11 Citations (Scopus)
16 Citations (Scopus)
2008

Differential apoptotic effect of wogonin and nor-wogonin via stimulation of ROS production in human leukemia cells

Chow, J-M., Huang, G. C., Shen, S-C., Wu, C. Y., Lin, C-W. & Chen, Y-C., Apr 1 2008, In : Journal of Cellular Biochemistry. 103, 5, p. 1394-1404 11 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
93 Citations (Scopus)
156 Citations (Scopus)
2007
78 Citations (Scopus)

Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells

Ko, C. H., Shen, S. C., Yang, L. Y., Lin, C. W. & Chen, Y. C., Oct 15 2007, In : International Journal of Cancer. 121, 8, p. 1670-1679 10 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)
32 Citations (Scopus)
23 Citations (Scopus)