Cheng-Hsien Chen

2018

Alleviative effect of fucoxanthin-containing extract from brown seaweed Laminaria japonica on renal tubular cell apoptosis through upregulating Na⁺/H⁺ exchanger NHE1 in chronic kidney disease mice

Chen, Y. C., Cheng, C. Y., Liu, C. T., Sue, Y. M., Chen, T. H., Hsu, Y. H., Hwang, P. A. & Chen, C. H., Oct 5 2018, In : Journal of Ethnopharmacology. 224, p. 391-399 9 p.

Research output: Contribution to journal › Article

Laminaria

Seaweed

Sodium-Hydrogen Antiporter

Chronic Renal Insufficiency

Protein Isoforms

2017

4 Citations (Scopus)

Far infrared promotes wound healing through activation of Notch1 signaling

Hsu, Y. H., Lin, Y. F., Chen, C. H., Chiu, Y. J. & Chiu, H. W., Aug 22 2017, (Accepted/In press) In : Journal of Molecular Medicine. p. 1-11 11 p.

Research output: Contribution to journal › Article

Wound Healing

Keratinocytes

Skin

Gene Expression

Wounds and Injuries

9 Citations (Scopus)

Far-infrared protects vascular endothelial cells from advanced glycation end products-induced injury via PLZF-mediated autophagy in diabetic mice

Chen, C. H., Chen, T. H., Wu, M. Y., Chou, T. C., Chen, J. R., Wei, M. J., Lee, S. L., Hong, L. Y., Zheng, C. M., Chiu, I. J., Lin, Y. F., Hsu, C. M. & Hsu, Y. H., Jan 10 2017, In : Scientific Reports. 7, 40442.

Research output: Contribution to journal › Article

Advanced Glycosylation End Products

Zinc Fingers

Autophagy

Leukemia

Endothelial Cells

8 Citations (Scopus)

Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice

Chiu, H. W., Chen, C. H., Chen, Y. J. & Hsu, Y. H., Mar 1 2017, In : PLoS One. 12, 3, e0174042.

Research output: Contribution to journal › Article

photoaging

Skin Aging

Hairless Mouse

Fibroblasts

skin (animal)

8 Citations (Scopus)

Oligo-fucoidan prevents renal tubulointerstitial fibrosis by inhibiting the CD44 signal pathway

Chen, C-H., Sue, Y-M., Cheng, C-Y., Chen, Y. C., Liu, C. T., Hsu, Y-H., Hwang, P. A., Huang, N. J. & Chen, T-H., Jan 18 2017, In : Scientific Reports. 7, 40183.

Research output: Contribution to journal › Article

Signal Transduction

Fibrosis

Kidney

Chronic Renal Insufficiency

Catenins

2016

21 Citations (Scopus)

Far-infrared promotes burn wound healing by suppressing NLRP3 inflammasome caused by enhanced autophagy

Chiu, H. W., Chen, C. H., Chang, J. N., Chen, C. H. & Hsu, Y. H., Feb 11 2016, (Accepted/In press) In : Journal of Molecular Medicine. p. 1-11 11 p.

Research output: Contribution to journal › Article

Inflammasomes

Autophagy

Wound Healing

Tumor Necrosis Factor Receptor-Associated Peptides and Proteins

Ubiquitination

10 Citations (Scopus)

Multifunctions of Excited Gold Nanoparticles Decorated Artificial Kidney with Efficient Hemodialysis and Therapeutic Potential

Chen, H. C., Cheng, C. Y., Lin, H. C., Chen, H. H., Chen, C. H., Yang, C. P., Yang, K. H., Lin, C. M., Lin, T. Y., Shih, C. M. & Liu, Y. C., Aug 3 2016, In : ACS Applied Materials and Interfaces. 8, 30, p. 19691-19700 10 p.

Research output: Contribution to journal › Article

Gold

Dialysis

Nanoparticles

Oxidative stress

Platelets

2015

10 Citations (Scopus)

Lycopene inhibits cyclic strain-induced endothelin-1 expression through the suppression of reactive oxygen species generation and induction of heme oxygenase-1 in human umbilical vein endothelial cells

Sung, L. C., Chao, H. H., Chen, C. H., Tsai, J. C., Liu, J. C., Hong, H. J., Cheng, T-H. & Chen, J. J., Jun 1 2015, In : Clinical and Experimental Pharmacology and Physiology. 42, 6, p. 632-639 8 p.

Research output: Contribution to journal › Article

Heme Oxygenase-1

Human Umbilical Vein Endothelial Cells

Endothelin-1

Reactive Oxygen Species

Gene Expression

6 Citations (Scopus)

Peroxisome proliferator-activated receptor α protects renal tubular cells from gentamicin-induced apoptosis via upregulating Na⁺/H⁺ exchanger NHE1

Chen, C-H., Chen, T-H., Wu, M-Y., Chen, J. R., Hong, L. Y., Zheng, C., Chiu, I. J., Lin, Y-F. & Hsu, Y-H., Nov 23 2015, In : Molecular Medicine. 21, p. 886-899 14 p.

Research output: Contribution to journal › Article

Sodium-Hydrogen Antiporter

Peroxisome Proliferator-Activated Receptors

Gentamicins

Apoptosis

Kidney

5 Citations (Scopus)

Urinary neutrophil gelatinase-associated lipocalin is associated with heavy metal exposure in welding workers

Chuang, K. J., Pan, C. H., Su, C-L., Lai, C. H., Lin, W. Y., Ma, C. M., Ho, S. C., Bien, M. Y., Chen, C. H. & Chuang, H. C., Dec 17 2015, In : Scientific Reports. 5, 18048.

Research output: Contribution to journal › Article

Welding

Heavy Metals

Kidney

Wounds and Injuries

Biomarkers

2014

5 Citations (Scopus)

Lycopene inhibits urotensin-II-induced cardiomyocyte hypertrophy in neonatal rat cardiomyocytes

Chao, H. H., Sung, L-C., Chen, C. H., Liu, J. C., Chen, J. J. & Cheng, T-H., 2014, In : Evidence-based Complementary and Alternative Medicine. 2014, 724670.

Research output: Contribution to journal › Article

Cardiac Myocytes

Hypertrophy

Glycogen Synthase Kinases

Oxidation-Reduction

Reactive Oxygen Species

24 Citations (Scopus)

MicroRNA-328 inhibits renal tubular cell epithelial-to-mesenchymal transition by targeting the CD44 in pressure-induced renal fibrosis

Chen, C. H., Cheng, C. Y., Chen, Y. C., Sue, Y. M., Liu, C. T., Cheng, T-H., Hsu, Y. H. & Chen, T. H., Jun 11 2014, In : PLoS One. 9, 6, e99802.

Research output: Contribution to journal › Article

Epithelial-Mesenchymal Transition

kidney cells

fibrosis

MicroRNAs

microRNA

9 Citations (Scopus)

Protective effects of Zhibai Dihuang Wan on renal tubular cells affected with gentamicin-induced apoptosis

Hsu, Y. H., Chen, T. H., Wu, M. Y., Lin, Y. F., Chen, W. L., Cheng, T-H. & Chen, C. H., Jan 10 2014, In : Journal of Ethnopharmacology. 151, 1, p. 635-642 8 p.

Research output: Contribution to journal › Article

Gentamicins

Apoptosis

Kidney

Phellodendron

Anemarrhena

2013

10 Citations (Scopus)

Rosuvastatin inhibits pressure-induced fibrotic responses via the expression regulation of prostacyclin and prostaglandin E₂ in rat renal tubular cells

Chen, C. H., Cheng, C. Y., Chen, Y. C., Sue, Y. M., Hsu, Y. H., Tsai, W. L. & Chen, T. H., Jan 30 2013, In : European Journal of Pharmacology. 700, 1-3, p. 65-73 9 p.

Research output: Contribution to journal › Article

Epoprostenol

Dinoprostone

Kidney

Pressure

Peroxisome Proliferator-Activated Receptors

50 Citations (Scopus)

The secreted Klotho protein restores phosphate retention and suppresses accelerated aging in Klotho mutant mice

Chen, T. H., Kuro-O, M., Chen, C. H., Sue, Y. M., Chen, Y. C., Wu, H. H. & Cheng, C. Y., Jan 5 2013, In : European Journal of Pharmacology. 698, 1-3, p. 67-73 7 p.

Research output: Contribution to journal › Article

Phosphates

Premature Aging

Down-Regulation

Vascular Calcification

Phenotype

7 Citations (Scopus)

Urotensin II exerts antiapoptotic effect on NRK-52E cells through prostacyclin-mediated peroxisome proliferator-activated receptor alpha and Akt activation

Hsu, Y. H., Chen, T. H., Chen, Y. C., Cheng, C. Y., Sue, Y. M., Chen, J. R. & Chen, C. H., Dec 5 2013, In : Molecular and Cellular Endocrinology. 381, 1-2, p. 168-174 7 p.

Research output: Contribution to journal › Article

PPAR alpha

Epoprostenol

Chemical activation

Gentamicins

Kidney

2012

32 Citations (Scopus)

Far-infrared therapy induces the nuclear translocation of PLZF which inhibits VEGF-induced proliferation in human umbilical vein endothelial cells

Hsu, Y. H., Chen, Y. C., Chen, T. H., Sue, Y. M., Cheng, T-H., Chen, J. R. & Chen, C. H., Jan 23 2012, In : PLoS One. 7, 1, e30674.

Research output: Contribution to journal › Article

vascular endothelial growth factors

zinc finger motif

Zinc Fingers

Endothelial cells

Human Umbilical Vein Endothelial Cells

7 Citations (Scopus)

Long-term leptin treatment exerts a pro-apoptotic effect on renal tubular cells via prostaglandin E₂ augmentation

Hsu, Y. H., Cheng, C. Y., Chen, Y. C., Chen, T. H., Sue, Y. M., Tsai, W. L. & Chen, C. H., Aug 15 2012, In : European Journal of Pharmacology. 689, 1-3, p. 65-71 7 p.

Research output: Contribution to journal › Article

Leptin

Dinoprostone

Kidney

Gentamicins

Apoptosis

2011

9 Citations (Scopus)

Dipyridamole inhibits lipopolysaccharide-induced cyclooxygenase-2 and monocyte chemoattractant protein-1 via heme oxygenase-1-mediated reactive oxygen species reduction in rat mesangial cells

Chen, Y. C., Chen, C. H., Ko, W. S., Cheng, C. Y., Sue, Y. M. & Chen, T. H., Jan 10 2011, In : European Journal of Pharmacology. 650, 1, p. 445-450 6 p.

Research output: Contribution to journal › Article

Heme Oxygenase-1

Mesangial Cells

Dipyridamole

Chemokine CCL2

Cyclooxygenase 2

44 Citations (Scopus)

L-carnitine reduces doxorubicin-induced apoptosis through a prostacyclin-mediated pathway in neonatal rat cardiomyocytes

Chao, H. H., Liu, J. C., Hong, H. J., Lin, J. W., Chen, C. H. & Cheng, T-H., Jan 21 2011, In : International Journal of Cardiology. 146, 2, p. 145-152 8 p.

Research output: Contribution to journal › Article

Carnitine

Epoprostenol

Cardiac Myocytes

Doxorubicin

Apoptosis

35 Citations (Scopus)

Leptin reduces gentamicin-induced apoptosis in rat renal tubular cells via the PI3K-Akt signaling pathway

Chen, Y. C., Chen, C. H., Hsu, Y. H., Chen, T. H., Sue, Y. M., Cheng, C. Y. & Chen, T-W., May 11 2011, In : European Journal of Pharmacology. 658, 2-3, p. 213-218 6 p.

Research output: Contribution to journal › Article

Phosphatidylinositol 3-Kinase

Leptin

Gentamicins

Apoptosis

Kidney

2010

7 Citations (Scopus)

L-Carnitine attenuates angiotensin II-induced proliferation of cardiac fibroblasts: Role of NADPH oxidase inhibition and decreased sphingosine-1-phosphate generation

Chao, H. H., Chen, C. H., Liu, J. C., Lin, J. W., Wong, K. L. & Cheng, T-H., Jul 2010, In : Journal of Nutritional Biochemistry. 21, 7, p. 580-588 9 p.

Research output: Contribution to journal › Article

Carnitine

NADPH Oxidase

Fibroblasts

Angiotensin II

Epoprostenol

19 Citations (Scopus)

Propofol depresses angiotensin II-induced cell proliferation in rat cardiac fibroblasts

Cheng, T-H., Leung, Y. M., Cheung, C. W., Chen, C. H., Chen, Y. L. & Wong, K. L., Jan 2010, In : Anesthesiology. 112, 1, p. 108-118 11 p.

Research output: Contribution to journal › Article

Propofol

Angiotensin II

Fibroblasts

Cell Proliferation

Proto-Oncogene Proteins c-akt

40 Citations (Scopus)

Uric acid activates extracellular signal-regulated kinases and thereafter endothelin-1 expression in rat cardiac fibroblasts

Cheng, T-H., Lin, J. W., Chao, H. H., Chen, Y. L., Chen, C. H., Chan, P. & Liu, J. C., Feb 18 2010, In : International Journal of Cardiology. 139, 1, p. 42-49 8 p.

Research output: Contribution to journal › Article

Extracellular Signal-Regulated MAP Kinases

Endothelin-1

Uric Acid

Fibroblasts

Gene Expression

2009

62 Citations (Scopus)

Antioxidation and anti-inflammation by haem oxygenase-1 contribute to protection by tetramethylpyrazine against gentamicin-induced apoptosis in murine renal tubular cells

Sue, Y. M., Cheng, C. F., Chang, C. C., Chou, Y., Chen, C. H. & Juan, S. H., Mar 2009, In : Nephrology Dialysis Transplantation. 24, 3, p. 769-777 9 p.

Research output: Contribution to journal › Article

Heme Oxygenase (Decyclizing)

Gentamicins

Apoptosis

Inflammation

Kidney

5 Citations (Scopus)

Dipyridamole inhibits cobalt chloride-induced osteopontin expression in NRK52E cells

Chen, T. H., Chang, C. F., Yu, S. C., Wang, J. C., Chen, C. H., Chan, P. & Lee, H. M., Jun 24 2009, In : European Journal of Pharmacology. 613, 1-3, p. 10-18 9 p.

Research output: Contribution to journal › Article

Osteopontin

Dipyridamole

Heme Oxygenase-1

Mitogen-Activated Protein Kinase Phosphatases

Dual Specificity Phosphatase 1

Dipyridamole Inhibits Lipopolysaccharide-Induced Interleukin-6 Secretion via Activation of Mitogen-Activated Protein Kinase Phosphatase-1 in Rat Mesangial Cells

范揚智(Yang-Chih F, 鄭仲益(Chung-Yi C, 陳正憲(Cheng-Hsien C, 陳振文(Tzen-Wen C & 陳作孝(Tso-Hsiao C, 2009, In : Acta Nephrologica. 23, 1, p. 33-39 7 p.

Research output: Contribution to journal › Article

Mitogen-Activated Protein Kinase Phosphatases

Dual Specificity Phosphatase 1

Mesangial Cells

Dipyridamole

Lipopolysaccharides

14 Citations (Scopus)

Effects of propofol on cyclic strain-induced endothelin-1 expression in human umbilical vein endothelial cells

Cheng, T-H., Chen, J. J., Chen, C. H. & Wong, K. L., Jan 2009, In : Anesthesiology. 110, 1, p. 74-80 7 p.

Research output: Contribution to journal › Article

Human Umbilical Vein Endothelial Cells

Endothelin-1

Propofol

Extracellular Signal-Regulated MAP Kinases

Nitric Oxide

8 Citations (Scopus)

Mechanical stretch induces endothelial nitric oxide synthase gene expression in neonatal rat cardiomyocytes

Cheng, T-H., Chen, J. J. W., Shih, N. L., Lin, J. W., Liu, J. C., Chen, Y. L., Chen, C. H. & Chen, J. J., May 2009, In : Clinical and Experimental Pharmacology and Physiology. 36, 5-6, p. 559-566 8 p.

Research output: Contribution to journal › Article

Nitric Oxide Synthase Type III

Cardiac Myocytes

Gene Expression

Phosphoglycerate Kinase

Genes

30 Citations (Scopus)

Peroxisome proliferator-activated receptor alpha plays a crucial role in l-carnitine anti-apoptosis effect in renal tubular cells

Chen, H. H., Sue, Y. M., Chen, C. H., Hsu, Y. H., Hou, C-C., Cheng, C. Y., Lin, S. L., Tsai, W. L., Chen, T-W. & Chen, T. H., Oct 2009, In : Nephrology Dialysis Transplantation. 24, 10, p. 3042-3049 8 p.

Research output: Contribution to journal › Article

PPAR alpha

Carnitine

Apoptosis

Kidney

Gentamicins

22 Citations (Scopus)

Urotensin II-induced endothelin-1 expression and cell proliferation via epidermal growth factor receptor transactivation in rat aortic smooth muscle cells

Tsai, C. S., Loh, S. H., Liu, J. C., Lin, J. W., Chen, Y. L., Chen, C. H. & Cheng, T-H., Sep 2009, In : Atherosclerosis. 206, 1, p. 86-94 9 p.

Research output: Contribution to journal › Article

Endothelin-1

Epidermal Growth Factor Receptor

Transcriptional Activation

Smooth Muscle Myocytes

Cell Proliferation

26 Citations (Scopus)

Urotensin II induces rat cardiomyocyte hypertrophy via the transient oxidization of Src homology 2-containing tyrosine phosphatase and transactivation of epidermal growth factor receptor

Liu, J. C., Chen, C. H., Chen, J. J. & Cheng, T-H., Dec 2009, In : Molecular Pharmacology. 76, 6, p. 1186-1195 10 p.

Research output: Contribution to journal › Article

Phosphoric Monoester Hydrolases

Epidermal Growth Factor Receptor

Cardiac Myocytes

Hypertrophy

Transcriptional Activation

7 Citations (Scopus)

Urotensin II induces transactivation of the epidermal growth factor receptor via transient oxidation of SHP-2 in the rat renal tubular cell line NRK-52E

Sue, Y. M., Chen, C. H., Hsu, Y. H., Hou, C-C., Cheng, C. Y., Chen, Y. C., Lin, S. L., Chen, T-W. & Chen, T. H., 2009, In : Growth Factors. 27, 3, p. 155-162 8 p.

Research output: Contribution to journal › Article

Epidermal Growth Factor Receptor

Transcriptional Activation

Rats

Cells

Phosphorylation

2008

27 Citations (Scopus)

Involvement of reactive oxygen species in urotensin II-induced proliferation of cardiac fibroblasts

Chen, Y. L., Liu, J. C., Loh, S. H., Chen, C. H., Hong, C. Y., Chen, J. J. & Cheng, T. H., Sep 28 2008, In : European Journal of Pharmacology. 593, 1-3, p. 24-29 6 p.

Research output: Contribution to journal › Article

Reactive Oxygen Species

Fibroblasts

Cell Proliferation

Extracellular Signal-Regulated MAP Kinases

Phosphorylation

24 Citations (Scopus)

Prostacyclin protects renal tubular cells from gentamicin-induced apoptosis via a PPARα-dependent pathway

Hsu, Y. H., Chen, C. H., Hou, C. C., Sue, Y. M., Cheng, C. Y., Cheng, T. H., Lin, H., Tsai, W. L., Chan, P. & Chen, T. H., Mar 2008, In : Kidney International. 73, 5, p. 578-587 10 p.

Research output: Contribution to journal › Article

Peroxisome Proliferator-Activated Receptors

Epoprostenol

Gentamicins

Apoptosis

Kidney

46 Citations (Scopus)

Uric acid stimulates endothelin-1 gene expression associated with NADPH oxidase in human aortic smooth muscle cells

Chao, H. H., Liu, J. C., Lin, J. W., Chen, C. H., Wu, C. H. & Cheng, T. H., Nov 2008, In : Acta Pharmacologica Sinica. 29, 11, p. 1301-1312 12 p.

Research output: Contribution to journal › Article

NADPH Oxidase

Endothelin-1

Uric Acid

Smooth Muscle Myocytes

Gene Expression

2007

36 Citations (Scopus)

Peroxisomal proliferator-activated receptor-α protects renal tubular cells from doxorubicin-induced apoptosis

Lin, H., Hou, C. C., Cheng, C. F., Chiu, T. H., Hsu, Y. H., Sue, Y. M., Chen, T. H., Hou, H. H., Chao, Y. C., Cheng, T. H. & Chen, C. H., Nov 2007, In : Molecular Pharmacology. 72, 5, p. 1238-1245 8 p.

Research output: Contribution to journal › Article

Peroxisome Proliferator-Activated Receptors

Doxorubicin

Apoptosis

Kidney

Epoprostenol

55 Citations (Scopus)

Tanshinone IIA from Salvia miltiorrhiza induces heme oxygenase-1 expression and inhibits lipopolysaccharide-induced nitric oxide expression in RAW 264.7 cells

Chen, T. H., Hsu, Y. T., Chen, C. H., Kao, S. H. & Lee, H. M., Feb 2007, In : Mitochondrion. 7, 1-2, p. 101-105 5 p.

Research output: Contribution to journal › Article

Salvia miltiorrhiza

Heme Oxygenase-1

Lipopolysaccharides

Nitric Oxide

Anti-Inflammatory Agents

64 Citations (Scopus)

Tetramethylpyrazine protects rat renal tubular cell apoptosis induced by gentamicin

Juan, S. H., Chen, C. H., Hsu, Y. H., Hou, C. C., Chen, T. H., Lin, H., Chu, Y. L. & Sue, Y. M., Mar 2007, In : Nephrology Dialysis Transplantation. 22, 3, p. 732-739 8 p.

Research output: Contribution to journal › Article

Gentamicins

Apoptosis

Kidney

NF-kappa B

Reactive Oxygen Species

2006

31 Citations (Scopus)

Antiproliferative effect of isosteviol on angiotensin-II-treated rat aortic smooth muscle cells

Wong, K. L., Lin, J. W., Liu, J. C., Yang, H. Y., Kao, P. F., Chen, C. H., Loh, S. H., Chiu, W. T., Cheng, T-H., Lin, J. G. & Hong, H. J., Apr 2006, In : Pharmacology. 76, 4, p. 163-169 7 p.

Research output: Contribution to journal › Article

Angiotensin II

Smooth Muscle Myocytes

Endothelin-1

Reactive Oxygen Species

Stevia

40 Citations (Scopus)

Dipyridamole activation of mitogen-activated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW 264.7 cells

Chen, T. H., Kao, Y. C., Chen, B. C., Chen, C. H., Chan, P. & Lee, H. M., Jul 17 2006, In : European Journal of Pharmacology. 541, 3, p. 138-146 9 p.

Research output: Contribution to journal › Article

Mitogen-Activated Protein Kinase Phosphatases

Dual Specificity Phosphatase 1

Dipyridamole

Cyclooxygenase 2

Lipopolysaccharides

84 Citations (Scopus)

Reactive oxygen species generation is involved in epidermal growth factor receptor transactivation through the transient oxidization of Src homology 2-containing tyrosine phosphatase in endothelin-1 signaling pathway in rat cardiac fibroblasts

Chen, C. H., Cheng, T. H., Lin, H., Shih, N. L., Chen, Y. L., Chen, Y. S., Cheng, C. F., Lian, W. S., Meng, T. C., Chiu, W. T. & Chen, J. J., Apr 2006, In : Molecular Pharmacology. 69, 4, p. 1347-1355 9 p.

Research output: Contribution to journal › Article

Endothelin-1

Phosphoric Monoester Hydrolases

Epidermal Growth Factor Receptor

Transcriptional Activation

Reactive Oxygen Species

16 Citations (Scopus)

Src homology 2-containing phosphotyrosine phosphatase regulates endothelin-1-induced epidermal growth factor receptor transactivation in rat renal tubular cell NRK-52E

Cheng-Hsien, C., Yung-Ho, H., Yuh-Mou, S., Chun-Cheng, H., Horng-Mo, L., Huei-Mei, H. & Tso-Hsiao, C., Apr 2006, In : Pflugers Archiv European Journal of Physiology. 452, 1, p. 16-24 9 p.

Research output: Contribution to journal › Article

Protein Tyrosine Phosphatases

Endothelin-1

Epidermal Growth Factor Receptor

Transcriptional Activation

Rats

19 Citations (Scopus)

Tetramethylpyrazine attenuates adriamycin-induced apoptotic injury in rat renal tubular cells NRK-52E

Cheng, C. Y., Sue, Y. M., Chen, C. H., Hou, C-C., Chan, P., Chu, Y. L., Chen, T. H. & Hsu, Y. H., Aug 2006, In : Planta Medica. 72, 10, p. 888-893 6 p.

Research output: Contribution to journal › Article

doxorubicin

kidney cells

Doxorubicin

Rats

Kidney

23 Citations (Scopus)

The protective effect of prostacyclin on adriamycin-induced apoptosis in rat renal tubular cells

Chen, C. H., Lin, H., Hsu, Y. H., Sue, Y. M., Cheng, T. H., Chan, P. & Chen, T. H., Jan 4 2006, In : European Journal of Pharmacology. 529, 1-3, p. 8-15 8 p.

Research output: Contribution to journal › Article

Epoprostenol

Doxorubicin

Apoptosis

Kidney

Cyclooxygenase 1

2005

27 Citations (Scopus)

Inhibition of angiotensin II induced endothelin-1 gene expression by 17-β-oestradiol in rat cardiac fibroblast

Chao, H. H., Chen, J. J., Chen, C. H., Lin, H., Cheng, C. F., Lian, W. S., Chen, Y. L., Juan, S. H., Liu, J. C., Liou, J. Y., Chan, P. & Cheng, T-H., May 2005, In : Heart. 91, 5, p. 664-669 6 p.

Research output: Contribution to journal › Article

Endothelin-1

Angiotensin II

Estradiol

Fibroblasts

Gene Expression

8 Citations (Scopus)

Inhibition of cyclic strain-induced endothelin-1 secretion by tetramethylpyrazine

Bi, W. F., Yang, H. Y., Liu, J. C., Cheng, T. H., Chen, C. H., Shih, C. M., Lin, H., Wang, T. C., Lian, W. S., Chen, J. J., Chiu, H. C. & Chang, N. C., Jul 2005, In : Clinical and Experimental Pharmacology and Physiology. 32, 7, p. 536-540 5 p.

Research output: Contribution to journal › Article

Endothelin-1

Blood Vessels

Cysteine

Reactive Oxygen Species

Endothelial Cells

14 Citations (Scopus)

Inhibitory effect of trilinolein on endothelin-1-induced c-fos gene expression in cultured neonatal rat cardiomyocytes

Yang, H. Y., Liu, J. C., Chen, Y. L., Chen, C. H., Lin, H., Lin, J. W., Chiu, W. T., Chen, J. J. & Cheng, T-H., Aug 2005, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 372, 2, p. 160-167 8 p.

Research output: Contribution to journal › Article

fos Genes

Endothelin-1

Cardiac Myocytes

Gene Expression

Superoxides

31 Citations (Scopus)

Nitric oxide inhibits endothelin-1-induced cardiomyocyte hypertrophy through cGMP-mediated suppression of extracellular-signal regulated kinase phosphorylation

Cheng, T. H., Shih, N. L., Chen, S. Y., Lin, J. W., Chen, Y. L., Chen, C. H., Lin, H., Cheng, C. F., Chiu, W. T., Wang, D. L. & Chen, J. J., Oct 2005, In : Molecular Pharmacology. 68, 4, p. 1183-1192 10 p.

Research output: Contribution to journal › Article

Extracellular Signal-Regulated MAP Kinases

Endothelin-1

Cardiac Myocytes

Hypertrophy

Nitric Oxide

48 Citations (Scopus)

Role of mitogen-activated protein kinase pathway in reactive oxygen species-mediated endothelin-1-induced β-myosin heavy chain gene expression and cardiomyocyte hypertrophy

Cheng, T-H., Shih, N. L., Chen, C-H., Lin, H., Liu, J-C., Chao, H. H., Liou, J. Y., Chen, Y. L., Tsai, H. W., Chen, Y. S., Cheng, C. F. & Chen, J. J., Jan 2005, In : Journal of Biomedical Science. 12, 1, p. 123-133 11 p.

Research output: Contribution to journal › Article

Myosin Heavy Chains

Endothelin-1

Mitogen-Activated Protein Kinases

Cardiac Myocytes

Gene expression