Projects per year
Personal profile
Education
Experience
- 2019.08- Chair Professor, Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
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Dive into the research topics where Che-Kun Shen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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哺乳類動物DNA甲基化?的新功能─去DNA甲基化活性的生理角色, 調控機制, 與轉譯研究(1/3)
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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TDP-43蛋白在神經細胞中功能及在神經退化疾病上角色的基礎與轉譯研究(3/3)
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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TDP-43蛋白在神經細胞中功能及在神經退化疾病上角色的基礎與轉譯研究(2/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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Neurodegenerative Diseases( I )(1/3)
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
Research output
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Activation of a hippocampal CREB-pCREB-miRNA-MEF2 axis modulates individual variation of spatial learning and memory capability
Wang, I. F., Wang, Y., Yang, Y. H., Huang, G. J., Tsai, K. J. & Shen, C. K. J., Aug 2021, In: Cell Reports. 36, 5, 109477.Research output: Contribution to journal › Article › peer-review
Open Access -
A positive regulatory feedback loop between eklf/klf1 and tal1/scl sustaining the erythropoiesis
Hung, C. H., Lee, T. L., Huang, A. Y. S., Yang, K. C., Shyu, Y. C., Wen, H. C., Lu, M. J., Yuan, S. & Shen, C. K. J., Aug 2021, In: International journal of molecular sciences. 22, 15, 8024.Research output: Contribution to journal › Article › peer-review
Open Access -
Cabozantinib promotes erythroid differentiation in K562 erythroleukemia cells through global changes in gene expression and JNK activation
Fu, Y. H., Ou, D. L., Yang, Y. R., Su, K. W., Chen, C. Y., Tien, H. F., Lai, Z. S., Shen, C. K. J., Chien, H. F. & Lin, L. I., 2021, (Accepted/In press) In: Cancer Gene Therapy.Research output: Contribution to journal › Article › peer-review
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A robust TDP-43 knock-in mouse model of ALS
Huang, S. L., Wu, L. S., Lee, M., Chang, C. W., Cheng, W. C., Fang, Y. S., Chen, Y. R., Cheng, P. L. & Shen, C. K. J., Jan 21 2020, In: Acta neuropathologica communications. 8, 1, p. 3 3.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
Cytosolic calcium regulates cytoplasmic accumulation of tdp-43 through calpain-a and importin α3
Park, J. H., Chung, C. G., Park, S. S., Lee, D., Kim, K. M., Jeong, Y., Kim, E. S., Cho, J. H., Jeon, Y. M., Kim, H. J., Hwang, D., Lee, S. B. & Shen, C. K. J., Dec 2020, In: eLife. 9, p. 1-31 31 p., e60132.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus)
Datasets
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Additional file 1: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, Y. (Contributor), Huang, W. (Contributor), Lin, J. (Contributor), Kao, T. (Contributor), Lin, H. (Contributor), Lee, K. (Contributor), Lin, H. (Contributor), Shen, C. (Contributor), Chang, W. (Contributor) & Huang, C. (Contributor), Unknown Publisher, Nov 8 2018
DOI: 10.6084/m9.figshare.7313777.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Znf179_E3_ligase-mediated_TDP-43_polyubiquitination_is_involved_in_TDP-43-_ubiquitinated_inclusions_UBI_-related_neurodegenerative_pathology/7313777/1
Dataset
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MOESM1 of A robust TDP-43 knock-in mouse model of ALS
Huang, S. (Contributor), Wu, L. (Contributor), Lee, M. (Contributor), Chang, C. (Contributor), Cheng, W. (Contributor), Fang, Y. (Contributor), Chen, Y. (Contributor), Cheng, P. (Contributor) & Shen, C. (Contributor), Unknown Publisher, Jan 21 2020
DOI: 10.6084/m9.figshare.11686497.v1, https://springernature.figshare.com/articles/MOESM1_of_A_robust_TDP-43_knock-in_mouse_model_of_ALS/11686497/1
Dataset
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Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, Y. (Contributor), Huang, W. (Contributor), Lin, J. (Contributor), Kao, T. (Contributor), Lin, H. (Contributor), Lee, K. (Contributor), Lin, H. (Contributor), Shen, C. (Contributor), Chang, W. (Contributor) & Huang, C. (Contributor), Unknown Publisher, Nov 8 2018
DOI: 10.6084/m9.figshare.c.4294289.v1, https://figshare.com/collections/Znf179_E3_ligase-mediated_TDP-43_polyubiquitination_is_involved_in_TDP-43-_ubiquitinated_inclusions_UBI_-related_neurodegenerative_pathology/4294289/1
Dataset
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MOESM6 of A robust TDP-43 knock-in mouse model of ALS
Huang, S. (Contributor), Wu, L. (Contributor), Lee, M. (Contributor), Chang, C. (Contributor), Cheng, W. (Contributor), Fang, Y. (Contributor), Chen, Y. (Contributor), Cheng, P. (Contributor) & Shen, C. (Contributor), Unknown Publisher, Jan 21 2020
DOI: 10.6084/m9.figshare.11686530.v1, https://springernature.figshare.com/articles/MOESM6_of_A_robust_TDP-43_knock-in_mouse_model_of_ALS/11686530/1
Dataset
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MOESM11 of A robust TDP-43 knock-in mouse model of ALS
Huang, S. (Contributor), Wu, L. (Contributor), Lee, M. (Contributor), Chang, C. (Contributor), Cheng, W. (Contributor), Fang, Y. (Contributor), Chen, Y. (Contributor), Cheng, P. (Contributor) & Shen, C. (Contributor), Unknown Publisher, Jan 21 2020
DOI: 10.6084/m9.figshare.11686491.v1, https://springernature.figshare.com/articles/MOESM11_of_A_robust_TDP-43_knock-in_mouse_model_of_ALS/11686491/1
Dataset