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Personal profile


  • 2005 The National Defense University Ph.D./The Graduate Institute of Life Sciences(GILS)


  • 018- 臺北醫學大學轉譯醫學博士學位學程副教授
  • 2012-2018 臺北醫學大學轉譯醫學博士學位學程助理教授
  • 2005-2012 中央研究院博士後研究
  • 1999-2000 長庚大學研究助理 

Research Interests

  • Post-translational modification
  • Signal transduction in cancer
  • Gene transcriptional regulation
  • Molecular cell biology


Fingerprint Dive into the research topics where Che-Chang Chang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
Sumoylation Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Transforming Growth Factors Medicine & Life Sciences
Proteins Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Glycosylation Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
SUMO-1 Protein Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2018

Creating the SUMOylated-factor specific antibody and the application in biochemical analysis

Chang, C.


Project: A - Government Institutionb - Ministry of Science and Technology


Chang, C.


Project: C - Project of Alliancel - National Taiwan University of Science and Technology

The Molecular Basis of Senp2 in Regulating Smad4 Sumoylation and Its Functions in Triple Negative Breast Cancer

Chang, C.


Project: A - Government Institutionb - Ministry of Science and Technology


Chang, C.


Project: A - Government Institutionb - Ministry of Science and Technology

Research Output 2005 2019

  • 797 Citations
  • 10 h-Index
  • 24 Article
  • 1 Book
  • 1 Review article

Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 06 Biological Sciences 0601 Biochemistry and Cell Biology

Hung, P. F., Hong, T. M., Chang, C. C., Hung, C. L., Hsu, Y. L., Chang, Y. L., Wu, C. T., Chang, G. C., Chan, N. L., Yu, S. L., Yang, P. C. & Pan, S. H., Jan 6 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 5.

Research output: Contribution to journalArticle

Biological Science Disciplines
Cell Biology
2 Citations (Scopus)

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) promotes EGF receptor signaling of oral squamous cell carcinoma metastasis via the complex N-glycosylation

Chiang, W. F., Cheng, T. M., Chang, C. C., Pan, S. H., Changou, C. A., Chang, T. H., Lee, K. H., Wu, S. Y., Chen, Y. F., Chuang, K. H., Shieh, D. B., Chen, Y. L., Tu, C. C., Tsui, W. L. & Wu, M. H., Jan 4 2018, In : Oncogene. 37, 1, p. 116-127 12 p.

Research output: Contribution to journalArticle

Carcinoembryonic Antigen
Cell Adhesion Molecules
Epidermal Growth Factor Receptor
Squamous Cell Carcinoma
3 Citations (Scopus)

Quantitative Analysis of Glucose Metabolic Cleavage in Glucose Transporters Overexpressed Cancer Cells by Target-Specific Fluorescent Gold Nanoclusters

Cheng, T. M., Chu, H. L., Lee, Y. C., Wang, D. Y., Chang, C. C., Chung, K. L., Yen, H. C., Hsiao, C. W., Pan, X. Y., Kuo, T. R. & Chen, C. C., Mar 20 2018, In : Analytical Chemistry. 90, 6, p. 3974-3980 7 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
3 Citations (Scopus)
1 Citation (Scopus)

Serum ApoA4 levels predicted the progression of renal impairment in T2DM

Cheng, C-W., Chang, C-C., Chen, H-W., Lin, C-Y. & Chen, J-S., Apr 19 2018, In : European Journal of Clinical Investigation. p. e12937

Research output: Contribution to journalArticle

Medical problems
Diabetic Nephropathies
Diabetes Mellitus