TMU Research Center of Drug Discivery

Search results

• Structure-guided design of anti-cancer ribonucleotide reductase inhibitors

  Misko, T. A. (Contributor), Liu, Y. (Contributor), Harris, M. E. (Contributor), Oleinick, N. L. (Contributor), Pink, J. (Contributor), Lee, H. (Contributor) & Dealwis, C. G. (Contributor), Unknown Publisher, Jan 1 2019

  DOI: 10.6084/m9.figshare.7553114.v1, https://tandf.figshare.com/articles/Structure-guided_design_of_anti-cancer_ribonucleotide_reductase_inhibitors/7553114/1

  Dataset

• MOESM10 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Tsai, F. (Contributor), Lu, H. (Contributor), Lin, Y. (Creator), Chen, C. (Contributor), Wu, J. (Contributor), Wong, H. S. (Creator), Chang, W. (Contributor) & Liao, W. (Creator), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270412.v1, https://doi.org/10.6084%2Fm9.figshare.10270412.v1

  Dataset

• MOESM4 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Chen, C. (Contributor), Lu, H. (Contributor), Liao, W. (Creator), Wong, H. S. (Creator), Wu, J. (Contributor), Chang, W. (Contributor), Lin, Y. (Creator) & Tsai, F. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270445.v1, https://doi.org/10.6084%2Fm9.figshare.10270445.v1

  Dataset

• MOESM8 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Lu, H. (Contributor), Wong, H. S. (Creator), Chang, W. (Contributor), Lin, Y. (Creator), Tsai, F. (Contributor), Wu, J. (Contributor), Liao, W. (Creator) & Chen, C. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270466.v1, https://doi.org/10.6084%2Fm9.figshare.10270466.v1

  Dataset

• MOESM5 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

  Liu, J. (Creator), Chen, P. (Contributor), Chen, S. (Contributor), Chu, J. (Contributor), Chien, C. (Contributor), Yang, W. (Creator), Lo, W. (Creator), Hsu, T. (Contributor), Yang, K. (Creator), Chung, P. (Contributor), Chou, S. (Creator), Chang, K. (Contributor), Yang, S. (Creator), Chuang, J. (Creator), Huang, C. (Contributor) & Liu, M. (Creator), Figshare, 2019

  DOI: 10.6084/m9.figshare.10006868.v1, https://doi.org/10.6084%2Fm9.figshare.10006868.v1

  Dataset

• Additional file 1 of Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury

  Pan, S. (Contributor), Hsu, K. (Creator), Lin, T. E. (Creator), Lin, C. (Creator), Huang, H. (Contributor) & HuangFu, W. (Contributor), Figshare, 2020

  DOI: 10.6084/m9.figshare.11992497.v1, https://doi.org/10.6084%2Fm9.figshare.11992497.v1

  Dataset

• MOESM6 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

  Chuang, J. (Creator), Chen, S. (Contributor), Yang, K. (Creator), Chien, C. (Contributor), Liu, J. (Creator), Hsu, T. (Contributor), Chang, K. (Contributor), Yang, S. (Creator), Chu, J. (Contributor), Chou, S. (Creator), Lo, W. (Creator), Liu, M. (Creator), Huang, C. (Contributor), Yang, W. (Creator), Chen, P. (Contributor) & Chung, P. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.10006874.v1, https://doi.org/10.6084%2Fm9.figshare.10006874.v1

  Dataset

• Ring size changes in the development of class I HDAC inhibitors

  Lee, H. (Contributor), Cho, E. (Contributor), Tang, D. (Contributor) & Liu, C. (Contributor), figshare Academic Research System, Jan 1 2021

  DOI: 10.6084/m9.figshare.14843703.v1, https://tandf.figshare.com/articles/journal_contribution/Ring_size_changes_in_the_development_of_class_I_HDAC_inhibitors/14843703/1

  Dataset

• Additional file 5: of Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status

  Chang, L. (Contributor), Liou, J. (Creator), Lai, M. (Contributor), Chang, C. (Contributor), Tu, H. (Contributor), Chao, M. (Contributor), Pan, S. (Contributor), Chen, Y. (Creator) & Teng, C. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.8202902.v1, https://doi.org/10.6084%2Fm9.figshare.8202902.v1

  Dataset

• Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma

  Tsai, I. (Contributor), Kuo, C. (Contributor), Liou, J. (Creator) & Chang, J. (Contributor), Figshare, 2018

  DOI: 10.6084/m9.figshare.c.4052207.v1, https://doi.org/10.6084%2Fm9.figshare.c.4052207.v1

  Dataset

• Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury

  Lin, C. (Creator), Lin, T. E. (Creator), Pan, S. (Contributor), Hsu, K. (Creator), HuangFu, W. (Contributor) & Huang, H. (Contributor), Figshare, 2020

  DOI: 10.6084/m9.figshare.c.4896705.v1, https://doi.org/10.6084%2Fm9.figshare.c.4896705.v1

  Dataset

• Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

  Chien, C. (Contributor), Chuang, J. (Creator), Yang, S. (Creator), Yang, W. (Creator), Chen, P. (Contributor), Hsu, T. (Contributor), Huang, C. (Contributor), Lo, W. (Creator), Yang, K. (Creator), Liu, M. (Creator), Chu, J. (Contributor), Chung, P. (Contributor), Liu, J. (Creator), Chou, S. (Creator), Chen, S. (Contributor) & Chang, K. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.c.4705370.v1, https://doi.org/10.6084%2Fm9.figshare.c.4705370.v1

  Dataset

• CCDC 2000792: Experimental Crystal Structure Determination

  Chu, H. (Contributor), Chang, J. (Contributor), Tsai, F. (Contributor), Lin, T. E. (Contributor), Cheng, T. (Contributor), Hsieh, C. (Contributor), Kapoor, M. (Contributor), Hsu, K. (Contributor), Hsu, M. (Contributor) & Horng, J. (Contributor), Cambridge Crystallographic Data Centre, 2020

  DOI: 10.5517/ccdc.csd.cc254zp0, https://doi.org/10.5517%2Fccdc.csd.cc254zp0

  Dataset

• Additional file 3 of EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody

  HuangFu, W. (Creator), Sung, T. (Creator), Lee, Y. (Contributor), Pan, S. (Creator), Cheng, Y. (Creator), Chang, F. (Creator), Wei, P. (Contributor), Huang, C. (Contributor), Huang, H. (Contributor) & Cheng, C. (Creator), Figshare, 2021

  DOI: 10.6084/m9.figshare.14228284.v1, https://doi.org/10.6084%2Fm9.figshare.14228284.v1

  Dataset

• Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation

  Chan, Y. (Contributor), Cheng, Y. (Creator), Liao, P. (Contributor), Li, C. (Creator), Lin, F. (Contributor), Ho, J. (Contributor), Chen, C. (Contributor) & Tsai, C. (Contributor), Figshare, 2021

  DOI: 10.6084/m9.figshare.c.5263303.v1, https://doi.org/10.6084%2Fm9.figshare.c.5263303.v1

  Dataset

• MOESM8 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

  Chung, P. (Contributor), Chen, S. (Contributor), Hsu, T. (Contributor), Liu, M. (Creator), Lo, W. (Creator), Chu, J. (Contributor), Yang, K. (Creator), Yang, S. (Creator), Liu, J. (Creator), Chuang, J. (Creator), Yang, W. (Creator), Huang, C. (Contributor), Chien, C. (Contributor), Chang, K. (Contributor), Chen, P. (Contributor) & Chou, S. (Creator), Figshare, 2019

  DOI: 10.6084/m9.figshare.10006883.v1, https://doi.org/10.6084%2Fm9.figshare.10006883.v1

  Dataset

• Additional file 1 of EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody

  Cheng, Y. (Creator), Cheng, C. (Creator), HuangFu, W. (Creator), Pan, S. (Creator), Sung, T. (Creator), Chang, F. (Creator), Huang, H. (Contributor), Huang, C. (Contributor), Wei, P. (Contributor) & Lee, Y. (Contributor), Figshare, 2021

  DOI: 10.6084/m9.figshare.14228278.v1, https://doi.org/10.6084%2Fm9.figshare.14228278.v1

  Dataset

• Associations of genetic variants of endothelin with cardiovascular complications in patients with renal failure

  Kao, C. (Contributor), Cheng, S. (Creator), Wu, M. (Creator), Chien, S. (Creator), Lu, H. (Contributor), Hsu, Y. (Creator), Zhang, Y. (Creator), Wu, M. (Creator) & Chang, W. (Contributor), Figshare, 2017

  DOI: 10.6084/m9.figshare.c.3874468.v1, https://doi.org/10.6084%2Fm9.figshare.c.3874468.v1

  Dataset

• Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model

  Chiu, H. (Creator), Yeh, Y. (Creator), Wang, Y. (Contributor), Huang, W. (Contributor), Ho, S. (Contributor), Lin, P. (Contributor) & Wang, Y. (Contributor), Figshare, 2016

  DOI: 10.6084/m9.figshare.c.3697276.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276.v1

  Dataset

• Additional file 1 of Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer

  Liu, E. (Contributor), Wang, C. (Contributor), Chuang, K. (Contributor), Chen, F. (Creator), Wu, T. (Contributor), Chen, C. (Creator), Chen, I. (Creator), Lin, R. (Creator), Wang, Y. (Contributor), Lu, Y. (Contributor), Liao, T. (Contributor), Chen, H. (Creator), Cheng, T. (Creator) & Cheng, Y. (Creator), Figshare, 2020

  DOI: 10.6084/m9.figshare.12885938.v1, https://doi.org/10.6084%2Fm9.figshare.12885938.v1

  Dataset

• Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer

  Wang, C. (Contributor), Chen, F. (Creator), Chen, H. (Creator), Wang, Y. (Contributor), Chen, I. (Creator), Liao, T. (Contributor), Lu, Y. (Contributor), Chuang, K. (Contributor), Wu, T. (Contributor), Cheng, Y. (Creator), Lin, R. (Creator), Chen, C. (Creator), Cheng, T. (Creator) & Liu, E. (Contributor), Figshare, 2020

  DOI: 10.6084/m9.figshare.c.5105096.v1, https://doi.org/10.6084%2Fm9.figshare.c.5105096.v1

  Dataset

• A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies

  Hsieh, Y. (Creator), Liao, J. (Creator), Chuang, K. (Creator), Ho, K. (Creator), Hong, S. (Creator), Liu, H. (Creator), Huang, B. (Creator), Chen, I. (Creator), Liu, Y. (Creator), Wang, J. (Creator), Tsai, H. (Creator), Su, Y. (Creator), Wang, Y. (Creator) & Cheng, T. (Creator), Figshare, 2022

  DOI: 10.6084/m9.figshare.c.5819661.v1, https://springernature.figshare.com/collections/A_universal_in_silico_V_D_J_recombination_strategy_for_developing_humanized_monoclonal_antibodies/5819661/1

  Dataset

• MOESM3 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Liao, W. (Creator), Chang, W. (Contributor), Wu, J. (Contributor), Tsai, F. (Contributor), Lin, Y. (Creator), Wong, H. S. (Creator), Chen, C. (Contributor) & Lu, H. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270439.v1, https://doi.org/10.6084%2Fm9.figshare.10270439.v1

  Dataset

• MOESM2 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Lin, Y. (Creator), Chen, C. (Contributor), Liao, W. (Creator), Wu, J. (Contributor), Tsai, F. (Contributor), Chang, W. (Contributor), Lu, H. (Contributor) & Wong, H. S. (Creator), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270436.v1, https://doi.org/10.6084%2Fm9.figshare.10270436.v1

  Dataset

• Additional file 1: of CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation

  Chen, Y. (Contributor), Chuang, J. (Creator), Wang, S. (Creator), Kao, T. (Contributor), Lin, H. (Creator), Ko, C. (Contributor) & Hsu, T. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.8866895.v1, https://doi.org/10.6084%2Fm9.figshare.8866895.v1

  Dataset