TMU Research Center of Cell Therapy and Regeneration Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2023

• 1 Active
• 452 Finished

Projects per year

Search results

• The Imapct of Oxidative Stress on the Pathogenesis of COPD---An Ivestigation into Its Relationship with Abnormal Inflammation, Dna Instability, Epigenetics and Cell Metabolism

  Lee, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Oxidative Stress 47%
  • Inflammation 33%
  • Blood Cells 26%
  • Glucocorticoids 21%

• The Imapct of Oxidative Stress on the Pathogenesis of COPD---An Ivestigation into Its Relationship with Abnormal Inflammation, DNA Instability, Epigenetics and Cell Metabolism

  Lee, K.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Immuno-Modulatory Effects of Xanthophylls on Male Reproductive System

  Wu, T. & Huang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • xanthophylls 100%
  • selenites 79%
  • astaxanthin 76%
  • male fertility 29%
  • prostaglandin synthase 28%

• The Immuno-Modulatory Effects of Xanthophylls on Male Reproductive System

  Wu, T. & Huang, Y.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • xanthophylls 100%
  • selenites 79%
  • astaxanthin 76%
  • male fertility 29%
  • prostaglandin synthase 28%

• The Impacts of Sleep on Memory Consolidation in Alzheimer's Disease Animals

  Hu, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Alzheimer Disease 100%
  • Memory Consolidation 92%
  • REM Sleep 80%
  • Sleep 75%
  • Dementia 26%

• The Investigation of Anti-Microglia/Macrophage Mechanisms of Different Tak1/Tabs Regulators and Their Protective Effects in Intracerebral Hemorrhage and Brain Abscess

  Hsiao, G.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphotransferases 100%
  • Cerebral Hemorrhage 52%
  • Brain Abscess 51%
  • Microglia 40%
  • Macrophage Activation 27%

• The Investigation of Anti-Neuroinflammatory Constituents from Fungal Species and Their Protective Profiles in the Retinal Diseases(1/3)

  Hsiao, G.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Investigation of Anti-Neuroinflammatory Constituents from Fungal Species and Their Protective Profiles in the Retinal Diseases(2/3)

  Hsiao, G.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Investigation of Anti-Neuroinflammatory Mechanisms of Differential Histone Deacetylase Regulators and Their Therapeutic Profiles in Experimental Intracerebral Haemorrahge and Encephalitis

  Hsiao, G.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Encephalitis 100%
  • Monocytes 77%
  • Acetylation 73%
  • Microglia 71%
  • Psychological Inhibition 57%

• The Involvement of Il-21-Regulated Circulating Fibrocyte Activation in Chronic Obstructive Asthma(I)(1/3)

  Lin, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Molecular Mechanism of Graphene Combined with Platelet-Rich Plasma in Avascular Necrosis of Femoral Head: in Vitro and in Vivo Study

  Lee, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • necrosis 100%
  • thighs 87%
  • growth factors 46%
  • osteonecrosis 42%
  • graphene 42%

• The Neuroprotection Effect and Mechanism of Long Non-Coding RNA MALAT1 in Acute Ischemic Stroke

  Chi, N. & Hu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 100%
  • Long Noncoding RNA 67%
  • Ischemia 47%
  • Untranslated RNA 47%
  • Cell Line 24%

• The New Therapeutic Strategy of 2, 3, 5, 4’-Tetrahydroxystilbene-2-O-Β-D-Glucoside (Thsg) Derivatives on Human Dental Pulp Stem Cells-Based Periodontal Treatment

  Lee, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • resveratrol 100%
  • stem cells 59%
  • therapeutics 55%
  • tooth pulp 53%
  • cell proliferation 42%

• The New Therapeutic Strategy of 2, 3, 5, 4’-Tetrahydroxystilbene-2-O-Β-D-Glucoside (Thsg) Derivatives on Human Dental Pulp Stem Cells-Based Periodontal Treatment

  Lee, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • resveratrol 100%
  • stem cells 59%
  • therapeutics 55%
  • tooth pulp 53%
  • cell proliferation 42%

• The New Therapeutic Strategy of 2, 3, 5, 4’-Tetrahydroxystilbene-2-O-Β-D-Glucoside (Thsg) Derivatives on Human Dental Pulp Stem Cells-Based Periodontal Treatment(3/3)

  Lee, S.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • resveratrol 100%
  • stem cells 59%
  • therapeutics 55%
  • tooth pulp 53%
  • cell proliferation 42%

• The Novel Development of Continuous Bladder Volume Measurement System

  Chen, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • bladder 100%
  • catheters 25%
  • sensors (equipment) 22%
  • drug therapy 7%
  • urine 6%

• The Potential Role of Glycogen Synthase Kinase-3 in Dengue Virus-Infected Mononuclear Phagocytes

  Lin, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycogen Synthase Kinase 3 100%
  • Dengue Virus 93%
  • Virus Diseases 47%
  • Interleukin-10 35%
  • Cellular Immunity 28%

• The Pre-Clinical Assessment of the Anti-Tumor Efficacy of a Protein Vaccine and Mesenchymal Stem Cell Combined Therapy, Using Non-Invasive Molecular Imaging Technology

  Wu, A. T. & Deng, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Vaccines 100%
  • Molecular Imaging 78%
  • Neoplasms 75%
  • Suicide 61%
  • Mesenchymal Stem Cells 59%

• The Protective Effect of Plzf and Annexin A1 on Diabetic Tubulopathy in the Pparα Signaling Pathway

  Hsu, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • PPAR alpha 100%
  • Promyelocytic Leukemia Zinc Finger Protein 66%
  • Annexin A1 54%
  • Kidney 39%
  • Autophagy 25%

• The Protective Effect of PLZF Nuclear Translocation against Advanced Glycation End Product-Induced Endothelial Injury in Diabetes and Its Molecular Mechanism

  Chen, C. & Hsu, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Promyelocytic Leukemia Zinc Finger Protein 100%
  • Protein Transport 32%
  • Human Umbilical Vein Endothelial Cells 27%
  • Advanced Glycation End Products 26%
  • Autophagy 17%

• The Publication of Journal of Biomedical Science

  Chang, W.

  1/1/15 → 3/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Scholarly Communication 100%
  • Taiwan 99%
  • Publications 83%
  • Biological Science Disciplines 62%
  • Information Dissemination 59%

• The Publication of Journal of Biomedical Science

  Chang, W.

  1/1/12 → 2/28/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Scholarly Communication 100%
  • Taiwan 99%
  • Publications 83%
  • Biological Science Disciplines 62%
  • Information Dissemination 59%

• The Publication of Journal of Biomedical Science

  Chang, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Publication of Journal of Biomedical Science

  Chang, W.

  1/1/11 → 12/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Scholarly Communication 100%
  • Taiwan 99%
  • Publications 83%
  • Biological Science Disciplines 62%
  • Information Dissemination 59%

• The Publication of Journal of Biomedical Science

  Chang, W.

  1/1/14 → 12/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Scholarly Communication 100%
  • Taiwan 99%
  • Publications 83%
  • Biological Science Disciplines 62%
  • Information Dissemination 59%

• The Publication of Journal of Biomedical Science

  Chang, W.

  1/1/17 → 3/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Taiwan 100%
  • medical sciences 73%
  • peers 59%
  • reports (publications) 56%
  • communication (human) 55%

• The Publication of Journal of Biomedical Science (1/3)

  Chang, W.

  1/1/13 → 2/28/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Scholarly Communication 100%
  • Taiwan 99%
  • Publications 83%
  • Biological Science Disciplines 62%
  • Information Dissemination 59%

• Therapeutic Potentials of Exosomes from Mesenchymal Stem Cell on Mitigating Cardiac Alterations and Their Effects on Modulating Oxidation, Inflammation, Mitochondrial Dysfunction and Insulin Resistance in Obesity Mice and Obesity Mice with Sepsis

  Huang, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Therapeutic Potentials of Peptide-Based Cytokine Binding Decoy against Sepsis and Its Effects on Modulating Inflammation, Oxidation, Apoptosis, Autophagy and Inflammasome

  Huang, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sepsis 100%
  • Peptides 37%
  • Cytokine Receptors 31%
  • Cytokines 24%
  • Inflammasomes 23%

• Therapeutic Potentials of Peptide-Based Cytokine Binding Decoy against Sepsis and Its Effects on Modulating Inflammation, Oxidation, Apoptosis, Autophagy and Inflammasome

  Huang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sepsis 100%
  • Peptides 37%
  • Cytokine Receptors 31%
  • Cytokines 24%
  • Inflammasomes 23%

• The Relationship between Sleep and Memory in Alzheimer Animal

  Hu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Alzheimer Disease 100%
  • Memory Consolidation 93%
  • REM Sleep 91%
  • Sleep 85%
  • Dementia 30%

• Thermodynamic Stability and Folding Kinetics of Membrane Proteins

  Chang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • protein 100%
  • membrane 79%
  • trapping 76%
  • folding 48%
  • thermodynamics 22%

• Thermodynamic Stability and Folding Kinetics of Membrane Proteins(2/2)

  Chang, Y.

  8/1/18 → 9/30/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • protein 100%
  • membrane 79%
  • trapping 76%
  • folding 48%
  • thermodynamics 22%

• The Role and Mechanism of Dendritic Cell Pd-L1/Pd-L2 Dysregulation in Aberrant Inflammation of Copd

  Lee, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The role and molecular mechanism of PPARα in acute kidney injury: focus on the protective effect in renal tubular cell

  Hsu, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • PPAR alpha 100%
  • MicroRNAs 54%
  • Type C Phospholipases 39%
  • Kidney 30%
  • Acute Kidney Injury 20%

• The Role and Molecular Mechanism of Pparα in Acute Kidney Injury: Focus on the Protective Effect in Renal Tubular Cell

  Hsu, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • PPAR alpha 100%
  • MicroRNAs 59%
  • Type C Phospholipases 43%
  • Kidney 33%
  • Acute Kidney Injury 22%

• The Role and Molecular Mechanism of PPARα in Acute Kidney Injury---Focus on the Protective Effect in Renal Tubular Cell

  Hsu, Y., Chen, T. & Chen, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • PPAR alpha 100%
  • MicroRNAs 54%
  • Type C Phospholipases 39%
  • Kidney 30%
  • Acute Kidney Injury 20%

• The Role and Molecular Mechanism of Urotensin II in Renal Disease: Focus on Tubular Injury and Renal Fibrosis

  Hsu, Y., Chen, T. & Chen, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • urotensin II 100%
  • Kidney 27%
  • Fibrosis 11%
  • Wounds and Injuries 10%
  • Renal Insufficiency 8%

• The Role of Amyloid-Beta in the Late-Onset Post-Stroke Vascular Cognitive Impairment (I)

  Hu, C., Wu, C., Chiou, H. & Chi, N.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cognitive Dysfunction 100%
  • Blood Vessels 79%
  • Amyloid 57%
  • Stroke 46%
  • Dementia 45%

• The Role of Amyloid-Beta in the Late-Onset Post-Stroke Vascular Cognitive Impairment( II )

  Hu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Amyloid-Beta in the Late-Onset Post-Stroke Vascular Cognitive Impairment( III )

  Hu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-1 in Fibrosis-promoted Liver Cancer Progression

  Wu, M.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • Galectin 1 100%
  • Liver Neoplasms 33%
  • Myofibroblasts 29%
  • Fibrosis 22%
  • Liver Cirrhosis 19%

• The Role of Galectin-1 in Fibrosis-promoted Liver Cancer Progression

  Wu, M.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Galectin 1 100%
  • Liver Neoplasms 33%
  • Myofibroblasts 29%
  • Fibrosis 22%
  • Liver Cirrhosis 19%

• The Role of Galectin-1 in Liver Fibrosis

  Wu, M.

  1/1/13 → 3/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-1 in Liver Fibrosis-Promoted Stem-Like Cell Properties and Sorafenib-Refractoriness of Hbv-Related Hepatocellular Carcinoma(2/3)

  Wu, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-1 in Liver Fibrosis-Promoted Stem-Like Cell Properties and Sorafenib-Refractoriness of Hbv-Related Hepatocellular Carcinoma(I)(1/3)

  Wu, M.

  8/1/18 → 8/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-3 in Ceacam6 Enhanced Egfr Signaling and Its Implication in Head and Neck Cancer Therapy

  Wu, M.

  8/1/18 → 7/30/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Carcinoembryonic Antigen 100%
  • Cell Adhesion Molecules 98%
  • Galectin 3 64%
  • Squamous Cell Carcinoma of Head and Neck 43%
  • Cetuximab 24%

• The Role of Inflammatory Gene Polymorphisms on Risk of Post-Stroke Vascular Dementia (I)

  Chiou, H., Chi, N., Lin, H., Wu, C., Hsieh, F., Hu, C. & Hsieh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 93%
  • Cognitive Dysfunction 89%
  • Blood Vessels 52%
  • Inflammation 36%
  • Whole Exome Sequencing 16%

• The Role of Neuropilin-1 Glycosylation in Galectin-1 Induced Activation of Hepatic Stellate Cells and Liver Fibrosis

  Wu, M. & Yang, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Galectin 1 100%
  • Neuropilin-1 68%
  • Liver Cirrhosis 28%
  • Platelet-Derived Growth Factor Receptors 24%
  • thiodigalactoside 12%

• The Role of Neuropilin-1 Glycosylation in Galectin-1 Induced Activation of Hepatic Stellate Cells and Liver Fibrosis

  Wu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Galectin 1 100%
  • Neuropilin-1 68%
  • Liver Cirrhosis 28%
  • Platelet-Derived Growth Factor Receptors 24%
  • thiodigalactoside 12%