TMU Research Center of Cell Therapy and Regeneration Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2023

• 1 Active
• 452 Finished

Projects per year

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• Application of Wearable Wireless Pulse Positioning System to Predict the Prognosis and to Avoid Sudden Death of Dialysis Patients

  Kao, W., Wu, M., Chen, R. & Chen, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dialysis 100%
  • Particle accelerators 6%

• Characterization of Thalamocortical Dysrhythmia in Mild Traumatic Brain Injury Using Simultaneous Mri and Eeg Measurements and Pre-Clinical N-Acetylcysteine Treatment Response

  Chen, C., Liu, H., Tseng, S., Lane, T. J., Lu, C., Chiang, Y. & Tsai, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acetylcysteine 44%
  • Post-Concussion Syndrome 17%
  • Neuroimaging 15%
  • Electroencephalography 14%
  • Atrophy 9%

• Motion-Sensitive MR Imaging in Characterizing Brain Compliance in Cerebral Venous Hypertension: A Translational Study between Humans and Rats

  Lu, C., Liu, H., Chen, C. & Tsai, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Brain 100%
  • Cerebrospinal fluid 69%
  • Magnetic resonance 62%
  • Compliance 52%
  • Imaging techniques 46%

• Functional Role of Growth Factor-Induced Metabolic Enzymes Expression in Cancer Cell Anti-Oxidation and Drug Resistance

  Chang, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epidermal Growth Factor 100%
  • Enzymes 83%
  • Neoplasms 82%
  • Drug Resistance 46%
  • Carcinogenesis 39%

• Application of Scaffold in Ovarian Transplantation for Female Fertility Preservation: an in vivo Transgenic Mouse Model (II)

  Chen, C., Tzeng, C. & Tseng, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sphingosine 100%
  • vascular endothelial growth factors 67%
  • phosphates 52%
  • female fertility 30%
  • autografting 18%

• Dissected the Role of Glucose-Regulated Protein 94 (GRP94),The Clinically Therapeutic Implication and Drug Development in Colon Cancer

  Wei, P. & Chang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • glucose-regulated proteins 100%
  • Colonic Neoplasms 43%
  • Colorectal Neoplasms 38%
  • Neoplasms 23%
  • Neoplasm Metastasis 19%

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-6 100%
  • Hepatocellular Carcinoma 94%
  • Hypoxia 55%
  • Drug Resistance 32%
  • Neoplasms 30%

• The Potential Role of Glycogen Synthase Kinase-3 in Dengue Virus-Infected Mononuclear Phagocytes

  Lin, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycogen Synthase Kinase 3 100%
  • Dengue Virus 93%
  • Virus Diseases 47%
  • Interleukin-10 35%
  • Cellular Immunity 28%

• A Mind-Body Approach to Study Irritable Bowel Syndrome: Role of Psychological Distress, Effectiveness and Mechanisms of Mindfulness Training(1/3)

  Tsai, P., Chang, C. & Chen, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mindfulness 100%
  • Depression 82%
  • Anxiety 79%
  • Self-Help Groups 49%
  • Urbanization 35%

• Subproject 2---Establishment of a General Multi-Input Multi-Output Platform for Assistive Technology Followed by Developing Individual-Specific Systems: for the Quadriplegic (Themes: E1)

  Chen, S., Peng, C., Pan, L., Jian, W. & Liou, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Education 100%
  • Demonstrations 96%
  • Set theory 75%
  • Feedback 74%
  • Industry 51%

• Valproate治療腦外傷病人的臨床研究

  Chang, C., Chiang, Y., Liao, K., Yang, S., Wu, C. & Chen, K.

  8/7/14 → 8/6/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Traumatic Brain Injury 100%
  • Valproic Acid 97%
  • Therapeutic Uses 31%
  • Histone Deacetylases 29%
  • Glycogen 26%

• Development of 3d-Printing Dynamic Orthosis-For Hemiplegic Lower Limbs( II )

  Chen, S., Lai, C., Ou, K. & Peng, C.

  9/1/15 → 8/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases --Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (II)

  Huang, Y.

  10/1/15 → 9/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Implantable Rat ECG Measurement Device Based on Wireless Charge Technique and IMU motion Detection

  Liu, J.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• New drug development using dengue virus-infected mouse models(I)

  Lin, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-1 in Fibrosis-promoted Liver Cancer Progression

  Wu, M.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Galectin 1 100%
  • Liver Neoplasms 33%
  • Myofibroblasts 29%
  • Fibrosis 22%
  • Liver Cirrhosis 19%

• 探討精神分裂症藥物之抗乳癌幹細胞潛力與訊息調控機制

  Lin, C.

  3/1/15 → 12/31/16

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 生物矽轉換成中孔生物活性玻璃應用於肌腱骨頭癒合

  Chen, C.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › l - National Taiwan Ocean University

• 初探以立體列印開發個人化乳癌放療輔具之可行性

  Lu, L.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › j - National Taipei University of Technology

• The Publication of Journal of Biomedical Science

  Chang, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 105年度第二期癌症研究計畫-臺北醫學大學

  Yen, Y., Whang-Peng, J., Liu, L. & Chang, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Neoplasms 100%
  • Breast Neoplasms 71%
  • Antibodies 52%
  • Computational Biology 40%
  • Nicotine 34%

• Development of Ophthalmic Nanomedicine for Corneal Neovascularization Treatment

  Tseng, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Cornea 100%
  • Nanomedicine 81%
  • Eye 59%
  • Nanoparticles 47%
  • Corneal Neovascularization 45%

• Establishing Health and Welfare Biotechnology Electronic Database Sharing Platform, Promoting Evidence-Based Medicine and Disseminating Technology Knowledge in Taiwan

  Chen, C., Tam, K., Chen, K., Hou, W. & Bai, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Healthcare 100%
  • evidence 76%
  • welfare 56%
  • ministry 47%
  • health 44%

• Functional Outcomes and Cognitive Interventions in Older People following Traumatic Brain Injury

  Lin, M., Tsai, S., Chen, S., Chiang, Y., Liou, T., Lin, Y. & Shu Kei Lam, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Traumatic Brain Injury 100%
  • Tai Ji 13%
  • Brain Death 11%
  • Executive Function 9%
  • Activities of Daily Living 9%

• 生命科技群組政府科技發展計畫規劃及審議之研究

  Chang, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展具有近紅外光熱效應與螢光影像之奈米金抗癌藥物載體

  Mi, F.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › j - National Taipei University of Technology

• 人文思維在科學脈絡的闡發

  Lin, C.

  2/1/16 → 1/31/17

  Project: A - Government Institution › d - Ministry of Education

• Investigation of the cerebral perfusion changes in patients with mild traumatic brain injury using 3D bSSFP arterial spin labeling MRI

  Liu, H., Tsai, P., Chen, C. & Lu, C.

  2/1/16 → 1/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 神經醯胺生成於麻醉劑異丙酚刺激的巨噬細胞：分子機制與其角色

  Lin, C.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 牛樟芝萃取物Antraquinonol對大腸癌幹細胞之抑制潛力與分子標的之探討

  Lin, C.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• Cell Sheet Engineering for Primary Corneal Endothelial Cells and Its Animal Model

  Tseng, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endothelial Cells 100%
  • Transplants 31%
  • Cornea 31%
  • Polyglutamic Acid 27%
  • polyvinylidene fluoride 26%

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• The Investigation of Anti-Microglia/Macrophage Mechanisms of Different Tak1/Tabs Regulators and Their Protective Effects in Intracerebral Hemorrhage and Brain Abscess

  Hsiao, G.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphotransferases 100%
  • Cerebral Hemorrhage 52%
  • Brain Abscess 51%
  • Microglia 40%
  • Macrophage Activation 27%

• The Studies of Cxcl12 on Mycobacterium Tuberculosis-Induced Fibrocyte Activation and Pulmonary Fibrosis

  Lin, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Fibrosis 100%
  • Mycobacterium tuberculosis 84%
  • Tuberculosis 80%
  • Myofibroblasts 49%
  • Connective Tissue Growth Factor 43%

• 幹細胞基礎研究與前臨床動物試驗

  Huang, Y.

  8/1/16 → 7/31/17

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• A Multi-Sensitive Chitosan Nanomicelles for Targeted Anticancer Drug Delivery

  Mi, F.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chitosan 100%
  • Hyaluronic Acid 93%
  • Sodium Nitrite 51%
  • Deacetylation 47%
  • Pluronic 45%

• To Investigate the Mode of Galectin-1 and Neuropilin-1 Interactions in Carcinoma-Associated Fibroblasts and Its Implications in Oral Cancer Therapy

  Wu, M.

  8/1/15 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neuropilins 100%
  • Fibroblasts 91%
  • Polysaccharides 77%
  • Carcinoma 72%
  • Mouth Neoplasms 22%

• Effects of Uteroplacental Insufficiency and Hyperoxia on Lung Development and Epigenetic Alterations in the Rat Offspring(3/3)

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fetal Growth Retardation 100%
  • Hyperoxia 99%
  • Receptor for Advanced Glycation End Products 74%
  • Epigenomics 69%
  • Lung 48%

• Application of the Combination of Decelluarized Extracellular Matrix Grafted by Graphene and Bone Marrow Aspirate Concentrates on the Healing of Partial Tear of Anterior Cruciate Ligament

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • anterior cruciate ligament 100%
  • bone marrow 53%
  • extracellular matrix 44%
  • concentrates 35%
  • graphene 28%

• Studied the Roles of Grp94 in the Progression and Metastasis of Esophageal Squamous Carcinoma, Mechanism Dissection, and Drug Development

  Chang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Esophageal Neoplasms 100%
  • glucose-regulated proteins 96%
  • Squamous Cell Carcinoma 17%
  • Neoplasms 15%
  • Endoplasmic Reticulum Stress 15%

• The New Therapeutic Strategy of 2, 3, 5, 4’-Tetrahydroxystilbene-2-O-Β-D-Glucoside (Thsg) Derivatives on Human Dental Pulp Stem Cells-Based Periodontal Treatment

  Lee, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • resveratrol 100%
  • stem cells 59%
  • therapeutics 55%
  • tooth pulp 53%
  • cell proliferation 42%

• Platelets and Platelet-Derived Microparticles for Trojan Horse Cancer Therapy (THCt)(2/3)

  Burnouf, T. P. R.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • doxorubicin 100%
  • microparticles 83%
  • cancer therapy 31%
  • drug carriers 16%
  • neoplasms 16%

• 肺部炎症暨纖維化之轉譯研究

  Lin, C.

  8/1/16 → 7/31/17

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Anti-Aging Effect with the Associated Mechanism by PRP (Platelet-Rich Plasma) in Cartilage---A Fibronectin Fragment Model(3/3)

  Lee, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibronectins 100%
  • cartilage 63%
  • Toll-like receptor 2 58%
  • osteoarthritis 50%
  • chondrocytes 42%

• The Role of Amyloid-Beta in the Late-Onset Post-Stroke Vascular Cognitive Impairment( II )

  Hu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Sp1 in Cancer Metastatic Progression( I )

  Chang, W.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasms 100%
  • Neoplasm Metastasis 39%
  • Transcriptome 23%
  • Stomach Neoplasms 22%
  • Lung Neoplasms 20%

• Kaempferol Contained Nanomedicine as Eye-Drop for Corneal Neovascularization Treatment : Formulation, Anti-Angiogenesis Mechanism and Therapeutic Outcome Evaluation

  Tseng, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cornea 100%
  • Nanomedicine 81%
  • Eye 52%
  • Ophthalmic Solutions 50%
  • Nanoparticles 47%

• The Protective Effect of Plzf and Annexin A1 on Diabetic Tubulopathy in the Pparα Signaling Pathway

  Hsu, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • PPAR alpha 100%
  • Promyelocytic Leukemia Zinc Finger Protein 66%
  • Annexin A1 54%
  • Kidney 39%
  • Autophagy 25%

• Make a Portable/Wearable Kidney Possible – Development of Microtube Array Membrane (Mtam) Dialyzer – Study on Uremic Toxins Removal

  Wu, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Membranes 100%
  • Dialysis 95%
  • Equipment and Supplies 66%
  • Artificial Kidneys 55%
  • 4-cresol sulfate 34%