TMU Research Center of Cell Therapy and Regeneration Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2023

• 1 Active
• 452 Finished

Projects per year

Search results

• Radiogenomics of Malignant Gliomas by Linking Physiological Mr Imaging, Histopathological Patterns, and Genetic Alternations: a Translational Study from Rat to Man(2/3)

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glioblastoma 100%
  • Glioma 51%
  • Biomarkers 36%
  • Multiparametric Magnetic Resonance Imaging 15%
  • Neoplasms 14%

• Regulation of Pluripotency in Germline Stem Cells: the Effect of Crosstalk between Satb2, Igf-1r, and Laminin Niches on Cell Fate Determination

  Kuo, Y.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Repositioning Drug Therapies for Traumatic Brain Injury

  Chiu, W., Chang, C. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Wounds and Injuries 37%
  • Dipeptidyl-Peptidase IV Inhibitors 33%
  • Incretins 33%
  • Acetylcysteine 28%

• Role and Use of Blood Protein Fractions in Translational Therapy

  Burnouf, T. P. R.

  1/1/13 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role and Use of Blood Protein Fractions in Translational Therapy

  Burnouf, T. P. R.

  11/1/12 → 10/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Role of Activating Transcription Factor 3 in the Protective Effect of Resveratrol in Cardiomyocytes

  Liu, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Resveratrol 100%
  • Activating Transcription Factor 3 81%
  • Doxorubicin 63%
  • Cardiac Myocytes 47%
  • Activating Transcription Factors 25%

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related Hcc under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-6 100%
  • Hepatocellular Carcinoma 94%
  • Hypoxia 55%
  • Drug Resistance 32%
  • Neoplasms 30%

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-6 100%
  • Hepatocellular Carcinoma 94%
  • Hypoxia 55%
  • Drug Resistance 32%
  • Neoplasms 30%

• Role of high cell density in pIGF1R/EpCAM-induced Sorafenib resistance in HBV-HCC

  Huang, Y.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Niche Inflammatory Cytokine and Epigenetic Regulation in Expressions of Pluripotent Transcription Factor Oct4 and Sorafenib Refractoriness in Hbv-Related Hepatocellular Carcinoma and Its Clinical Implication.(I)(1/3)

  Huang, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Niche Inflammatory Cytokine and Epigenetic Regulation in Expressions of Pluripotent Transcription Factor Oct4 and Sorafenib Refractoriness in Hbv-Related Hepatocellular Carcinoma and Its Clinical Implication.( II )

  Huang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Organic Anion Transporter in Renal Tubular Injury---A Gateway to Hurt

  Wu, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Organic Anion Transporter in Renal Tubular Injury---A Gateway to Hurt

  Wu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Organic Anion Transporters 52%
  • Kidney 45%
  • Single Nucleotide Polymorphism 40%
  • Messenger RNA 27%

• Role of Organic Anion Transporter in Renal Tubular Injury---A Gateway to Hurt

  Wu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Organic Anion Transporters 52%
  • Kidney 45%
  • Single Nucleotide Polymorphism 40%
  • Messenger RNA 27%

• Role of Renin-Angiotensin System in Hyperoxia-Induced Lung Fibrosis

  Chen, C., Chou, H. & Wang, L.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hyperoxia 100%
  • Fibrosis 65%
  • Renin-Angiotensin System 60%
  • Connective Tissue Growth Factor 58%
  • Bronchopulmonary Dysplasia 45%

• Role of Sp-family in lung tumorigenesis

  Chang, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung 100%
  • Lung Neoplasms 73%
  • Carcinogenesis 61%
  • Doxycycline 61%
  • Neoplasms 43%

• Role of Sp-Family in Lung Tumorigenesis

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung 100%
  • Lung Neoplasms 73%
  • Carcinogenesis 61%
  • Doxycycline 61%
  • Neoplasms 43%

• Role of Sp-Family in Lung Tumorigenesis

  Chang, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung 100%
  • Lung Neoplasms 73%
  • Carcinogenesis 61%
  • Doxycycline 61%
  • Neoplasms 43%

• Roles of calcium channel in ER(先期補助)

  Wu, M.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Serum Free Cultivation of Multi-Layered Oral Mucosa Epithelial Cell Sheet for Autologous Corneal Epithelium Repairing and Its Animal Model

  Tseng, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • epithelium 100%
  • digestive tract mucosa 88%
  • epithelial cells 53%
  • disulfide bonds 45%
  • Lens 43%

• Short-Chain Fatty Acids Act as Anti-Allergic Regulators on Immune Effector Cells and Exert Immune-Modulatory Effects on Ovalbumin-Induced Allergic Diseases in Mice

  Lee, Y. & Hsiao, G.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Volatile Fatty Acids 100%
  • Phenylbutyrates 27%
  • Mast Cells 25%
  • Immunoglobulin E 19%
  • Asthma 16%

• Sleep and Memory Consilidation in Alzheimer Disease

  Hu, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep 100%
  • Memory Consolidation 87%
  • Alzheimer Disease 59%
  • Memory 31%
  • REM Sleep 28%

• Sorafenib抗藥性所誘發之肝癌惡病質與癌幹細胞特性之細胞療法：利用全身安全性之人類胎盤蛻膜間葉幹細胞標靶TNFα-IL6之免疫調控與攜帶奈米藥物對抗Sorafenib抗藥性肝癌之雙功能策略(先期補助)

  Huang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › f - Other (Funded by Government)

• Studied the Roles of Grp94 in the Progression and Metastasis of Esophageal Squamous Carcinoma, Mechanism Dissection, and Drug Development

  Chang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Esophageal Neoplasms 100%
  • glucose-regulated proteins 96%
  • Squamous Cell Carcinoma 17%
  • Neoplasms 15%
  • Endoplasmic Reticulum Stress 15%

• Studies on the Molecular Mechanism of Thrombin-Induced Connective Tissue Growth Factor (CTGF) Expression in Lung Fibroblasts

  Lin, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Connective Tissue Growth Factor 100%
  • Thrombin 61%
  • Fibroblasts 24%
  • MAP Kinase Kinase Kinase 5 20%
  • Transcription Factor AP-1 18%

• Study of glycosyl hydrolase and carbohydrate interaction by silicon nanowire effect

  Mi, F.

  1/1/14 → 9/30/15

  Project: C - Project of Alliance › j - National Taipei University of Technology

• Study of Nano-Size Memberane Tube for Tendon to Bone in Anterior Cruciate Ligament Reconstruction

  Chen, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tendons 100%
  • anterior cruciate ligament 79%
  • periosteum 55%
  • polyhydroxyalkanoates 53%
  • bones 46%

• Study of Nano-Size Memberane Tube for Tendon to Bone in Anterior Cruciate Ligament Reconstruction

  Chen, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Nano-Size Memberane Tube for Tendon to Bone in Anterior Cruciate Ligament Reconstruction

  Chen, C. & Lee, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tendons 100%
  • anterior cruciate ligament 79%
  • periosteum 55%
  • polyhydroxyalkanoates 53%
  • bones 46%

• Study of pre-clinical biocompatibility and safety of nanocomposite materials for orthopaedic implant

  Tseng, C.

  2/26/13 → 12/31/13

  Project: A - Government Institution › f - Other (Funded by Government)

  • bones 100%
  • orthopedics 93%
  • prostheses 56%
  • biocompatible materials 39%
  • biocompatibility 27%

• Study of Rich Platelets Plasma and Alginate Encapsulated Synovial Fluid Mesenchymal Stem Cells for Repairing the Partial Tear of Cruciate Ligament

  Chen, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • ligaments 100%
  • synovial fluid 81%
  • mesenchymal stromal cells 80%
  • alginates 55%
  • hydrogels 24%

• Study of the Role of L1cam on Neuroendocrine Prostate Cancer Progression

  Hsieh, C.

  8/1/18 → 9/30/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • Neural Cell Adhesion Molecule L1 91%
  • Castration 16%
  • Phenotype 9%
  • RNA-Binding Proteins 5%

• Study on the Mechanism Involved in Nanoparticles-Induced Tight Junction and Aquaporins Damages in Endothelial Cells, as Well as the Effects on Physiological Function of Endothelial Barriers

  Li, C. & Cheng, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanoparticles 100%
  • Blood-Brain Barrier 69%
  • Aquaporins 65%
  • Tight Junction Proteins 39%
  • Permeability 35%

• Subproject 2---Establishment of a General Multi-Input Multi-Output Platform for Assistive Technology Followed by Developing Individual-Specific Systems: for the Quadriplegic (Themes: E1)

  Chen, S., Peng, C., Pan, L., Jian, W. & Liou, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Education 100%
  • Demonstrations 96%
  • Set theory 75%
  • Feedback 74%
  • Industry 51%

• Systemic Safety Allograft Strategies for Cell Therapeutic Product Development: Targeting Unmet Medical Need Human Chronic Inflammatory Disease - Diabetes Mellitus /Decubitus Wound, Severe Burn, and Multiple Sclerosis( III )

  Huang, Y.

  5/1/19 → 4/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting Novel D2r Heteroreceptor Complexes as Anti-Dengue Strategy by Interfering Viral Infection and Immunopathogenesis

  Lin, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Characterisitc of Trapezius Surface Myography during Sleep

  Kang, J., Hu, C., Chen, S. & Tseng, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Superficial Back Muscles 100%
  • Myalgia 51%
  • Sleep 36%
  • Posture 8%
  • Myofascial Pain Syndromes 6%

• The Clinical Study of Hydrophilic Electrospun (ES) Pla/Bioceramic Guided Tissue/Bone Regeneration (GTR/GBR) Membranes

  Lee, S. & Yang, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Guided Tissue Regeneration 100%
  • Periodontal Index 42%
  • Periodontal Diseases 36%
  • Membranes 30%
  • Tooth 24%

• The Differential Effect of Egf on the Induction of Cyclooxygenase-2 Expression in Squamous and Adenocarcinoma Cells

  Chang, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cyclooxygenase 2 100%
  • Epidermal Growth Factor 49%
  • Aryl Hydrocarbon Receptor Nuclear Translocator 40%
  • Adenocarcinoma 27%
  • Epithelial Cells 17%

• The Effect and Mechanisms of Chemotherapy in Recruit Inflammatory Cells into Tumor Microenvironment of Lung Cancer Patients

  Feng, P. & Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myeloid-Derived Suppressor Cells 100%
  • Neoplasms 26%
  • Tumor Microenvironment 25%
  • Lung Neoplasms 19%
  • Drug Therapy 19%

• The Effect of Endothelin-1 on Myofibroblast Transformation of Pleural Mesothelial Cells and Its Implications for Pleural and Pulmonary Fibrosis

  Chung, C. & Hsiao, G.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myofibroblasts 100%
  • Endothelin-1 85%
  • Fibrosis 70%
  • Pulmonary Fibrosis 54%
  • Epithelial-Mesenchymal Transition 49%

• The effects of anesthetic propofol on neutrophil survival

  Lin, C.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• The Effects of Melatonin on Proliferation, Osteogenic Differentiation and in Vivo Bone Regeneration of Dental Pulp-Derived Mesenchymal Stem Cells and Related Molecular Mechanisms

  Feng, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • mesenchymal stromal cells 100%
  • melatonin 88%
  • tooth pulp 57%
  • bones 52%
  • stem cells 45%

• The Evaluation and Developing of Evidence-Based Medicine Education

  Chen, C. & Chiu, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • medicine 100%
  • evidence 66%
  • performance monitoring 14%
  • health care 14%
  • Health care quality 13%

• The Functional Role of Pdk1 in Arnt Oncogene-Regulated Tumorigenesis and Tumor Progression

  Chang, W.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasms 100%
  • Enzymes 90%
  • Carcinogenesis 47%
  • Oncogenes 39%
  • Neoplasm Metastasis 38%

• The Functional Role of Pdk1 in Arnt Oncogene-Regulated Tumorigenesis and Tumor Progression

  Chang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasms 100%
  • Enzymes 90%
  • Carcinogenesis 47%
  • Oncogenes 39%
  • Neoplasm Metastasis 38%