TMU Research Center of Cancer Translational Medicine

Projects

Projects per year 2010 2014 2015 2016 2017 2018 2023

• 4 Active
• 536 Finished

Projects per year

Search results

• Finished

  Establishing the Disease and Genetic Risk Prediction Score of Cognitive Impairment to Early Prevent the Threat of Dementia

  Hsieh, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dementia 100%
  • Neurodegenerative Diseases 80%
  • Iron-Deficiency Anemias 78%
  • Taiwan 65%
  • Cognitive Dysfunction 65%

• 可卡因促使Sig-1R局部化於核膜與emerin-HDACs抑制因子複合物結合來調節MAOB表達(3/3)

  Chuang, J.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sigma-1 receptor 100%
  • Cocaine 63%
  • Monoamine Oxidase 40%
  • Co-Repressor Proteins 25%
  • emerin 24%

• ORMDL3在thrombin誘導IL-8/CXCL8表現及呼吸道發炎之角色探討(3/3)

  Chen, B.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orosomucoid 100%
  • Thrombin 74%
  • Interleukin-8 32%
  • Transcription Factor AP-1 27%
  • Asthma 24%

• A Wearable Device Evaluation for Medication Management in Patients Taking Sleep Medicine via Cloud Platform Development( II )

  Li, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Impacts of Obesity-Associated Alterations in Adipose-Derived Stem Cell on Tumor Development

  Deng, W.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Obesity 100%
  • Stem Cells 94%
  • Neoplastic Stem Cells 60%
  • Neoplasms 41%
  • Mesenchymal Stem Cells 38%

• ADAM9 調節 integrin b4 之轉換率以促使前列腺癌細胞移動及浸潤之研究(3/3)

  Sung, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • metastasis 100%
  • integrins 89%
  • neoplasm progression 42%
  • neoplasms 38%
  • neoplasm cells 32%

• 轉譯醫學研究法探討茶緩解菸害之機轉:乳癌和動脈粥狀硬化為例(3/3)

  Ho, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tea 100%
  • Nicotine 28%
  • Capsules 25%
  • Breast Neoplasms 21%
  • MicroRNAs 19%

• Studies on the Mechanisms of Histamine N-Methyltransferase (Hnmt)-Mediated Herceptinr Drug-Resistance in Breast Cancer Cells

  Ho, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Trastuzumab 89%
  • Breast Neoplasms 17%
  • Tissue Array Analysis 9%
  • Gene Expression Profiling 8%

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• Preclinical Assessment of Cadherin11 Antagonists for Treating Drug-Resistant Breast Cancer through Modulating Tumor Immunity and Suppression of Cancer Stem Cells

  Chao, T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteoblast cadherin 100%
  • Breast Neoplasms 37%
  • Neoplastic Stem Cells 31%
  • Neoplasm Metastasis 12%
  • Breast 7%

• Combination Treatment of Tetrac- and Cetuximab-Induced Anti-Proliferation in Colorectal Cancer with Different Apc Status( III )

  Lin, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Tmu Spark Taiwan-Anchor University Program

  Yen, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • industry 100%
  • Licensing of intellectual property 79%
  • budget plan 71%
  • expert 54%
  • basic research 47%

• Targeting Class III Phosphoinositide 3-Kinase (Pi3k) for Anticancer Drug Discovery

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphoinositide 100%
  • 3-Methyladenine 41%
  • Antineoplastic Agent 32%
  • Protein Synthesis 25%
  • LY294002 22%

• 新穎性pan-HDAC 抑制劑抑制血管新生之藥物研發與藥理作用機轉(3/3)

  Pan, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase Inhibitors 100%
  • Histone Deacetylases 39%
  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 20%
  • Animal Models 18%
  • Drug Discovery 17%

• 探討透過黑殭菌素B調控Nrf2/KEAP1在對於三陰性乳癌治療效果之轉譯研究

  Wu, S.

  6/1/16 → 5/31/17

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 組織胺甲基化轉移酵素於腸癌致癌機制探討

  Chen, L.

  6/1/16 → 5/31/17

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 探討透過黑殭菌素B調控Nrf2/KEAP1在對於三陰性乳癌治療效果之轉譯研究

  Wu, S.

  5/31/16 → 5/30/17

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 104-105年預防保健服務專案管理計畫-105年後續擴充

  Chiou, H.

  3/12/16 → 3/11/17

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 將生物資訊之方法和功能性研究應用於基因表達與乳癌危險性相關性

  Chang, W.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › q - Cathay General Hospital

• 緩激肽調控惡性神經膠瘤細胞基質金屬蛋白酶-13 表現和影響血瘤障壁通透性之研究

  Chen, R.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• N-methyl-D-aspartate receptor調控血腦障壁之角色探討

  Chen, R. & Wu, G.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• The role of miR-203 and miR-34a in EGFR activation prostate cancer metastasis

  Liu, Y.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Prostatic Neoplasms 100%
  • Genes 42%
  • Neoplasm Metastasis 17%
  • Phenotype 11%
  • Bone and Bones 11%

• In vitro, ex vivo and clinical characterization of novel Salmonella virulence genes

  Fang, S. & Huang, M.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Salmonella 100%
  • Virulence 62%
  • Salmonella Infections 59%
  • Salmonella typhimurium 54%
  • Genes 47%

• Development of DNA methylation biomarker for endometrial cancer detection

  Lai, H.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Endometrial Neoplasms 100%
  • DNA Methylation 24%
  • Sensitivity and Specificity 18%
  • Clinical Studies 16%
  • Biomarkers 15%

• Establishing Health and Welfare Biotechnology Electronic Database Sharing Platform, Promoting Evidence-Based Medicine and Disseminating Technology Knowledge in Taiwan

  Chen, C., Tam, K., Chen, K., Hou, W. & Bai, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Healthcare 100%
  • evidence 76%
  • welfare 56%
  • ministry 47%
  • health 44%

• 高功率奈米製程之摻鉺光纖雷射在皮膚分段光熱分解療法之應用

  HuangFu, W.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › j - National Taipei University of Technology

• 設計診斷治療型之鄰脂質奈米粒子於放射型治療上之研究

  Wu, S.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• 醫院所有權結構是否會影響醫院生產力與品質表現

  Chien, L.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › l - National Taiwan Ocean University

• 癌症早期發現相關策略研究－分癌別評估癌症篩檢執行人力與未來發展之需求：乳癌、子宮頸癌、大腸癌、口腔癌與肝癌(105年)

  Chen, L. & Wang, S.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Epigenetic Characterization of Ovarian Cancer Initiating Cells

  Lai, H.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Ovarian Neoplasms 100%
  • Neoplastic Stem Cells 64%
  • Epigenomics 43%
  • 5-hydroxymethylcytosine 16%
  • Stem Cell Research 14%

• Preclinical evaluation of novel selective HDAC6 inhibitors for human cancers treatment

  Pan, S.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Mesylates 100%
  • ricolinostat 43%
  • Heterografts 39%
  • Investigational New Drug Application 37%
  • Outsourced Services 35%

• 新聘教師研究補助

  Chen, L.

  1/1/16 → 12/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Social medicine discipline research Planning and Promotion project

  Chiou, H.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 鱘龍魚軟骨萃取物於延緩老化之臨床前研究與產品開發

  Deng, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › e - Council of Agriculture

• 失眠患者之睡前準備穿戴式雲平台系統開發與驗證

  Li, Y.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• 合成選擇性HDAC6?抑制劑

  Liou, J.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 105年度第二期癌症研究計畫-臺北醫學大學

  Yen, Y., Whang-Peng, J., Liu, L. & Chang, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Neoplasms 100%
  • Breast Neoplasms 71%
  • Antibodies 52%
  • Computational Biology 40%
  • Nicotine 34%

• 臺北醫學大學附設醫院之疾病個案收集與建立臺灣人體生物資料庫

  Yen, Y.

  1/1/16 → 12/31/16

  Project: A - Government Institution › f - Other (Funded by Government)

• Evaluation on prevention for metabolic syndrome and diabetes mellitus through lifestyle modification intervention in pre-diabetic subjects (100-104)

  Chiou, H.

  12/31/15 → 12/30/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 104年度科學及技術類委託研究計畫「健保已給付新藥副作用之風險評估_以口服抗凝血劑為例」計畫案

  Chien, L., Ko, Y., Chien, S. & Chi, N.

  12/23/15 → 12/22/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Service for Sharing Precious Instruments of Taipei Medical University

  Chen, Y., Liou, J. & Chien, L.

  12/1/15 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Reservation systems 100%
  • Mass spectrometers 91%
  • Nuclear magnetic resonance 77%
  • Magnetic resonance spectrometers 60%
  • Online systems 38%

• 新北市醫療照護資源垂直整合模式成效評估計畫

  Chiou, H.

  10/22/15 → 7/11/16

  Project: A - Government Institution › f - Other (Funded by Government)

• Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases --Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (II)

  Huang, Y.

  10/1/15 → 9/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立多構面癌症防治預測模式:以大腸癌為例－建立多構面癌症防治預測模式:以大腸癌為例

  Shao, Y.

  9/1/15 → 8/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Carcinogenic Mechanisms of Glucose Transporters in Gastrointestinal Cancer Cells and Its Clinical Therapeutic Applications

  Chen, L. & Wu, C.

  9/1/15 → 8/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glucose 100%
  • Antitumor 19%
  • Occurrence in Nature 17%
  • Pharmacological Metabolism 11%
  • Biological Role 8%

• A Phase I, First-In-Human, Dose-Seeking Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Orally Administered MPT0E028 in Subjects with Advanced Solid Malignancies without Standard Treatment (II)

  Liou, J.

  9/1/15 → 8/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Age-Related Hearing Loss (Presbycusis)---Cisd2 Deficiency Accelerate the Hearing Defect during Aging Process-Renew

  Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Presbycusis 100%
  • Hearing 57%
  • Longevity 37%
  • Inner Ear 22%
  • Cochlea 22%

• Elucidation of the Molecular Mechnism of Aglaia Elliptifolia Extract Rocaglamide Induced Cell Death in Breast Cancer Cells---PHB as a Target

  Huang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Rocaglamide 100%
  • Oncogenic 11%
  • Cell Death 8%

• Reflecting on Issues of End-Of-Life by Approaching Ventilator-Dependent Patients: an Interdisciplinary Educational Action Research

  Chen, C., Lin, W., Lin, S. & Tang, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • team teaching 100%
  • action research 70%
  • curriculum 64%
  • medicine 57%
  • dialogue 56%