TMU Research Center of Cancer Translational Medicine

Projects

Projects per year 2010 2014 2015 2016 2017 2018 2022

• 5 Active
• 531 Finished

Projects per year

Search results

• Social Medicine Discipline Research Planning and Promotion Project

  Chiou, H.

  1/1/15 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Social Medicine 100%
  • Congresses 85%
  • Fees and Charges 53%
  • Geriatric Nursing 35%
  • Research Design 34%

• Application and Mechanism of Novel Fluoro-Rutaecarpine on Inhibition of Inflammation Induced Endomt

  Lin, C.

  8/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibrosis 19%
  • Inflammation 15%
  • Sumoylation 5%

• 鱘龍魚軟骨萃取物於延緩老化之臨床前研究與產品開發

  Deng, W.

  1/1/15 → 12/31/15

  Project: A - Government Institution › e - Council of Agriculture

• Epigenetic Characterization of Ovarian Cancer Initiating Cells

  Lai, H. & Huang, R.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • Ovarian Neoplasms 100%
  • Neoplastic Stem Cells 64%
  • Epigenomics 43%
  • 5-hydroxymethylcytosine 16%
  • Stem Cell Research 14%

• 輻射誘導doxorubicin 釋放之研究:探討不同胺基酸分子設計之藥物載體(奈米藥物傳導Doxorubicin、Statin and Metformin 肝腫瘤超音波分子影像模型整合性研究)

  Wu, S.

  1/1/15 → 12/31/15

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• TMU103-AE1-B12

  Lee, K.

  1/1/15 → 12/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 104年度第二期癌症研究計畫-臺北醫學大學癌症研究中心計畫

  Yen, Y.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• A cohort study of chronic kidney disease (the 101th-104th year of the Republic Era)

  Lin, Y., Chiou, H., Hsu, Y., Wu, M., Hsieh, F., Bai, C., Hsieh, Y., Chien, L., Wang, Y., Wu, M., Yang, S., Lin, Y. & Lin, C.

  3/31/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Chronic Renal Insufficiency 100%
  • Taiwan 77%
  • Chronic Kidney Failure 68%
  • Annual Reports 21%
  • Data Systems 19%

• 建構領航國際之活躍老化監測暨決策支援系統-活躍老化資料倉儲與決策支援系統(104-107年)之需求規劃暨監造管理計畫

  Liu, C., Yeh, Y., Chiou, H. & Chi, M.

  4/30/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Preclinical evaluation of novel selective HDAC6 inhibitors for human cancers treatment

  Pan, S.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • ricolinostat 100%
  • Neoplasms 97%
  • Heterografts 90%
  • Investigational New Drug Application 86%
  • Pharmaceutical Preparations 62%

• Long-term follow-up study of health behaviors among adolescent cohort. (104年)

  Chiou, H., Chen, P., Chen, Y., Yang, S. & Chen, Y. C.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 急診室服務能力之人員配置評估模式建立

  Yeh, C.

  1/1/15 → 12/31/15

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• 雲林縣整合性社區健康篩檢工作成果評價分析計畫案

  Chen, L.

  6/18/15 → 12/10/15

  Project: A - Government Institution › f - Other (Funded by Government)

• Evaluation on prevention for metabolic syndrome and diabetes mellitus through lifestyle modification intervention in pre-diabetic subjects (100-104)

  Chiou, H., Bai, C., Tang, C., Yang, S., Su, C., Liou, T., Wang, S., Chen, J., Hsieh, A. & Huang, C.

  12/24/14 → 12/5/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Metabolic Syndrome 100%
  • Life Style 88%
  • Diabetes Mellitus 86%

• 經表皮塗抹硝酸甘油軟膏於痔瘡切除術後之止痛作用

  Tam, K.

  3/1/14 → 10/31/15

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• Identification of Rewired APC Mutation Signaling Network in Chemotherapy Resistant Response in Colorectal Cancer (I)

  Huang, T.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adenomatous Polyposis Coli 100%
  • Colorectal Neoplasms 44%
  • Mutation 34%
  • Drug Resistance 28%
  • Fluorouracil 17%

• A Phase I, First-In-Human, Dose-Seeking Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Orally Administered MPT0E028 in Subjects with Advanced Solid Malignancies without Standard Treatment (I)

  Liou, J.

  9/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 100%
  • Histones 39%
  • Vorinostat 30%
  • Erlotinib Hydrochloride 27%
  • Sorafenib 26%

• Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases---Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (I)

  Huang, Y.

  10/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Testicular Germ Cell Tumor 100%
  • Embryonic Stem Cells 77%
  • Epigenomics 75%
  • Seminoma 73%
  • Germ Cells 71%

• TGF-beta誘導人類大腸癌細胞CTGF表現之機轉研究

  Chen, B.

  6/1/14 → 8/31/15

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 北區高階生醫產業聚落及產業規劃-台灣遠距健康產業聚落發展先導計畫

  Yen, Y. & Chen, R.

  9/1/14 → 8/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• The Role of Wnt5a and Hsp90 in the Wnt/Beta-Catenin Signaling Pathway of Colorectal Cancer (I)

  Lee, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • beta Catenin 100%
  • Colorectal Neoplasms 78%
  • Wnt Signaling Pathway 55%
  • Adenomatous Polyposis Coli 52%
  • 5-(2,4-dihydroxy-5-isopropylphenyl)-4-(4-morpholin-4-ylmethylphenyl)isoxazole-3-carboxylic acid ethylamide 25%

• Characterization of 5-Hydroxymethylcytosine and Ten-to-Eleven Translocation Gene (TET) in Cervical Cancer

  Lai, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 5-hydroxymethylcytosine 100%
  • Uterine Cervical Neoplasms 38%
  • Epigenomics 20%
  • 5-Methylcytosine 17%
  • Carcinogenesis 9%

• Genetic Polymorphisms in microRNA and Risk of the Post-Thrombolytic Hyperglycemia in Acute Ischemic Stroke and Its Prognosis Study

  Hsieh, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hyperglycemia 100%
  • MicroRNAs 92%
  • Stroke 80%
  • Single Nucleotide Polymorphism 42%
  • Small Untranslated RNA 10%

• Genetic Polymorphisms of Calcium Channel in the Risk of Breast Cancer

  Chang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Calcium Channels 63%
  • Breast Neoplasms 60%
  • Genetic Polymorphisms 37%
  • Calcium 24%
  • Case-Control Studies 18%

• Roles of Toll-Like Receptor-4 and Hif-1 in Propofol-Involved Protection against Traumatic Brain Injury-Induced Dysfunction of the Blood-Brain Barrier

  Chen, R.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Blood-Brain Barrier 100%
  • Propofol 73%
  • Hypoxia 36%
  • Brain Edema 25%
  • Craniocerebral Trauma 22%

• The Association Study of Genetic Polymorphisms of Toll-Like Receptors on Ischemic Stroke (II)

  Chiou, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pre-Clinical and Clinical Study for Multi-Nation Intelligent Medication Safety System

  Li, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Decision support systems 100%
  • Security systems 98%
  • Health 71%
  • Automatic identification 58%
  • Health care 49%

• 抗氧化防禦基因標籤單核?酸多形性、氧化壓力生物標記與冠狀動脈心臟病之相關性(2/2)

  Yeh, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Analyses of ADAM9 on Integrin b4 Turnover to Facilitate Prostate Cancer Migration and Invasion

  Sung, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • metastasis 100%
  • integrins 89%
  • neoplasm progression 42%
  • prostatic neoplasms 38%
  • neoplasms 38%

• Study the Function and Regulation of miRNAs in Pancreatic Cancer Progression (I)

  Huang, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Pancreatic Neoplasms 93%
  • Neoplastic Stem Cells 42%
  • Neoplasms 28%
  • Neoplasm Metastasis 12%

• The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (II)

  Chen, B.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Translational Investigation for Tea Attenuate Smoking-Induced Disease---Breast Cancer and Atherosclerosis as a Mechanistic Study

  Ho, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tea 100%
  • Nicotine 26%
  • Capsules 23%
  • Breast Neoplasms 23%
  • Smoking 19%

• Cocaine Induces Sig-1R Nuclear Envelope Localization to Regulate MAOB Expression by Interacting with Emerin-HDACs Co-Repressor Complex

  Chuang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sigma-1 receptor 100%
  • Cocaine 63%
  • Monoamine Oxidase 42%
  • emerin 30%
  • Co-Repressor Proteins 29%

• Dementia Care and Quality Improvement

  Chien, L.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • dementia 100%
  • health insurance 28%
  • Medical records 19%
  • utilization 17%
  • resources 9%

• Investigation on the Epigenetic Regulation of Autophagy

  Yang, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Autophagy 100%
  • Enhancer of Zeste Homolog 2 Protein 91%
  • GSK343 51%
  • Triple Negative Breast Neoplasms 41%
  • Epigenomics 21%

• Chemo-Sensitizer Conjugated Carbon Nanotubes as a Novel Cancer Therapeutical Delivery System

  Cho, E.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Carbon Nanotube 100%
  • Radiation Sensitizing Agent 38%
  • Ribonucleotide 28%
  • Water Soluble 17%
  • Drug 12%

• Investigation of the Intrinsic Molecular Mechanisms of ETV6 That Contribute to Suppression of Metastasis and Sensitivity of Chemotherapy in Prostate Cancer

  Liu, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • Neoplasm Metastasis 28%
  • ras Genes 16%
  • Nuclear Receptor Co-Repressor 2 11%
  • Drug Therapy 11%

• The Imapct of Oxidative Stress on the Pathogenesis of COPD---An Ivestigation into Its Relationship with Abnormal Inflammation, Dna Instability, Epigenetics and Cell Metabolism

  Lee, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Oxidative Stress 47%
  • Inflammation 33%
  • Blood Cells 26%
  • Glucocorticoids 21%

• Role of miR-21 in Regulating TET I-Hydroxymethylcytosine and Chemotherapeutic Response in Colorectal Cancer (I)

  Yang, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • 5-hydroxymethylcytosine 84%
  • APC Genes 58%
  • DNA Methylation 55%
  • Adenomatous Polyposis Coli 51%

• Drug Discovery and Pharmacological Study of Novel pan-HDAC Inhibitors as Anti-Angiogenic Drugs

  Pan, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase Inhibitors 100%
  • Histone Deacetylases 36%
  • Drug Discovery 23%
  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 18%
  • Animal Models 16%

• Role of Oxidative Stress-triggered Redox Adaptation Mechanism and Genetically Endowed Expression Profile of Antioxidant Enzymes in the modulation of Intrinsic and Acquired Chemoand Radio-resistance of Human Hepatocellular Carcinoma Cells

  Chiou, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Radio 90%
  • Survivin 42%
  • Antioxidants 39%
  • Oxidation-Reduction 34%

• Combination Treatment of Tetrac- and Cetuximab-Induced Anti-Proliferation in Colorectal Cancer with Different APC Status (I)

  Lin, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tetraiodothyroacetic acid 100%
  • Cetuximab 77%
  • Adenomatous Polyposis Coli 38%
  • Colorectal Neoplasms 28%
  • Integrins 16%

• Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation: the Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example.

  Ho, Y. & Wu, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Gene Expression 46%
  • Tumor Microenvironment 40%
  • Hyaluronan Synthases 30%
  • Fibroblasts 29%

• 開發微米中空纖維陣列膜作為血液過濾器之研究

  Chen, C.

  6/1/14 → 7/31/15

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-6 100%
  • Hepatocellular Carcinoma 94%
  • Hypoxia 55%
  • Drug Resistance 32%
  • Neoplasms 30%

• Association between Lipid, Glucose Related Genes and Prognosis of Intra- and Extra-Cranial Stenosis in Stroke Patients

  Chiou, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 85%
  • Lipid Metabolism 84%
  • Homeostasis 64%
  • Glucose 63%
  • Antioxidants 46%

• Dissected the Role of Glucosed-Regulated Portein 78 in the Progression, Metastasis and Therapy of Colorectal Cancer

  Wei, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • colorectal neoplasms 100%
  • metastasis 69%
  • neoplasms 55%
  • endoplasmic reticulum 32%
  • death 27%

• 腫瘤相關巨噬細胞在誘發產生表皮生長因子受器酪胺酸酉每抑制劑的抗藥性的角色

  Feng, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• Bone-Marrow-Derived Mesenchymal Stem Cells in Prostate Cancer-Induced Bone Remodeling

  Hsieh, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipogenic 100%
  • Osteogenic 37%