TMU Research Center of Cancer Translational Medicine

Projects

Projects per year 2010 2014 2015 2016 2017 2018 2022

• 536 Finished

Projects per year

Search results

• Reflecting on Issues of End-Of-Life by Approaching Ventilator-Dependent Patients: an Interdisciplinary Educational Action Research

  Chen, C., Lin, W., Lin, S. & Tang, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • team teaching 100%
  • action research 70%
  • curriculum 64%
  • medicine 57%
  • dialogue 56%

• Study of Novel Genes Regulated by Aberrant DNA Methylation and Application in Colon Cancer Treatment

  Lin, R. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasm Genes 100%
  • Methylation 83%
  • Taiwan 82%
  • DNA Methylation 81%
  • Colonic Neoplasms 66%

• Pre-Clinical Evaluation of the Tumor Suppression Effectiveness and Mechanism of Small Molecule Drugs in Oral Cancer

  Chen, Y. & Wu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pharmaceutical Preparations 100%
  • Mouth Neoplasms 70%
  • Pharmaceutical Databases 22%
  • Neoplasm Genes 17%
  • Biological Products 15%

• A Toxicological Assessment of Air Pollution in the Vicinity of a Petrochemical Complex

  Chuang, H. & Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Particulate Matter 100%
  • Taiwan 54%
  • Toxicology 44%
  • Risk Assessment 38%
  • Methionine 19%

• HMGA2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers

  Lin, H., Chang, T. & Yen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 75%
  • tetraiodothyroacetic acid 70%
  • Colorectal Neoplasms 43%
  • Catenins 31%

• Effect of HMGA2 in Chemotherapy Response of Colorectal Cancer Patients with Different APC Status (II)

  Yen, Y., Cheng, Y. & Wei, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells (I)

  Yen, Y., Cheng, T. & Wu, A. T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Leukemia 100%
  • haptoglobin-hemoglobin complex 54%
  • Calicheamicins 53%
  • Neoplasms 49%
  • Multifunctional Nanoparticles 49%

• The Effect and Mechanisms of Chemotherapy in Recruit Inflammatory Cells into Tumor Microenvironment of Lung Cancer Patients

  Feng, P. & Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myeloid-Derived Suppressor Cells 100%
  • Neoplasms 26%
  • Tumor Microenvironment 25%
  • Lung Neoplasms 19%
  • Drug Therapy 19%

• Translational Investigation for Tea Attenuate Smoking-Induced Disease---Breast Cancer and Atherosclerosis as a Mechanistic Study

  Ho, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tea 100%
  • Nicotine 26%
  • Capsules 23%
  • Breast Neoplasms 23%
  • Smoking 19%

• The Role of Inflammatory Gene Polymorphisms on Risk of Post-Stroke Vascular Dementia (I)

  Chiou, H., Chi, N., Lin, H., Wu, C., Hsieh, F., Hu, C. & Hsieh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 93%
  • Cognitive Dysfunction 89%
  • Blood Vessels 52%
  • Inflammation 36%
  • Whole Exome Sequencing 16%

• The Role of SUV39H1 in Control of Inflammatory Genes and in Chronic Inflammation of Copd

  Lee, K., Feng, P. & Chuang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Inflammation 60%
  • Blood Cells 33%
  • Histone Deacetylase 2 32%
  • Glucocorticoids 27%

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation---The Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example

  Ho, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Gene Expression 46%
  • Tumor Microenvironment 40%
  • Hyaluronan Synthases 30%
  • Fibroblasts 29%

• 新北市醫療照護資源垂直整合模式成效評估計畫

  Chiou, H.

  10/22/15 → 7/11/16

  Project: A - Government Institution › f - Other (Funded by Government)

• TMU102-AE1-B44

  Liu, Y.

  7/1/14 → 6/30/16

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Activation Autophagy by the Combination of a Histone Deacetylase Inhibitor and Radiation Limits BNIP3 Regulation in Triple-Negative Breast Cancer Cells and Orthotopic Mouse Model

  Chiu, H. & Ho, Y.

  8/1/15 → 6/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • Histone Deacetylase Inhibitors 97%
  • Ionizing Radiation 42%
  • Autophagy 39%
  • human ERBB2 protein 25%

• 使用超音波導引腹橫肌平面神經阻斷術於減重手術後之止痛作用

  Tam, K.

  3/1/15 → 6/30/16

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 篩選一個具有保護神經而且可能發展為腦創傷治療藥物的Sigma 1受體促效劑

  Chuang, J.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• EGFR反式活化依賴NADPH oxidase/ROS/NF-kB路徑媒介thrombin誘導肺部上皮細胞IL-8/CXCL8表現之探討

  Chen, B.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 探討缺氧環境中透過Hif-2α支配的Igf-1r—Cxcr4訊號迴路調控小鼠生殖系幹細胞爬行作用機制

  Huang, Y.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 探討integrin αvβ3及EGFR間交叉效應對於甲狀腺賀爾蒙誘發大腸直腸癌細胞增生作用之影響

  Lin, H.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 運用化學基因體學方法開發新穎核糖核?酸還原?抑制劑用以治療大腸直腸癌

  Yang, P.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 從染色體中心節蛋白(CENP)家族中找尋可以用來當作卵巢癌的新腫瘤標的

  Lee, K.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 探討乳酸去氫?對胰臟癌Gemcitabine抗藥性的調控與影響

  Huang, M.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 卵巢癌幹細胞之代謝研究-I奉

  Lai, H.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 探討腫瘤抑制分子FOXO3a在胰臟癌gemcitabine抗藥性的角色

  Chen, H.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 退黑激素對於腎細胞癌侵犯轉移之療效及其相關調控機轉探討

  Chien, M.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 葡萄糖轉運受體於腸胃肝癌致癌作用與治療之探討

  Chen, L.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 探討TSA透過抑制YAP1訊息傳導作為治療抗藥性胰臟癌之潛力藥物

  Wu, S.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 探討Androgen receptor調控WNT 訊號傳遞在攝護腺癌之作用機轉

  Liu, Y.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• TGF-beta誘導人類肺癌細胞JARID2表現之機轉研究

  Chen, B.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 探討Hsp27在大腸癌的進行、轉移能力與治療上的角色及其作用機制

  Wei, P.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 104年度「空中救護審核機制計畫」

  Tsai, S., Whang-Peng, J., Liu, L., Chang, W., Ho, Y., Cheng, Y., Yeh, S., Chen, K., Sung, S., Hung, K., Chen, R., Chiou, H., Chen, C. & Li, Y.

  1/1/15 → 3/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• TMU103-AE1-B19

  Lee, Y.

  4/1/15 → 3/31/16

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 104-105年預防保健服務專案管理計畫

  Chiou, H.

  3/12/15 → 3/11/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 病毒性肝炎高盛行地區非酒精性脂肪肝疾病的盛行率與發生率風險因子

  Chen, L.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 第一型內皮細胞分子在C 型血管內皮生長因子調控肺腫瘤侵襲與轉移過程中扮演之角色探討

  Chien, M.

  3/1/14 → 2/29/16

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 探討propofol減緩敗血症傷害的機轉: 轉譯醫學研究

  Chen, R.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 探討細胞自噬在低氧調控多型性神經膠母細胞瘤生成過程所扮演的角色

  Chen, R.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 104年度「委託科技研究計畫--以資通訊科技提升照護品質」分項計畫5：長期照護服務導入資通訊科技之策略規劃

  Yen, Y., Chiou, H., Liu, C. & Lin, P.

  6/12/15 → 2/11/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Long-term Care 100%
  • System Development 22%
  • Needs Assessment 18%
  • Taiwan 17%
  • Managers 16%

• Application and Mechanism of Novel Fluoro-Rutaecarpine on Inhibition of Inflammation Induced Endomt

  Lin, C.

  8/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibrosis 19%
  • Inflammation 15%
  • Sumoylation 5%

• 臺北醫學大學自有貴重儀器共用服務計畫

  Lin, C.

  11/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 急診室服務能力之人員配置評估模式建立

  Yeh, C.

  1/1/15 → 12/31/15

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• In vitro, ex vivo and clinical characterization of novel Salmonella virulence genes

  Fang, S. & Huang, M.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • Salmonella 100%
  • Virulence 62%
  • Salmonella typhimurium 54%
  • Genes 47%
  • Defensins 33%

• TMU102-AE1-B25

  Chuang, J.

  1/1/14 → 12/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 104年度「健康資料加值應用雲端化服務計畫」

  Chiou, H., Hsu, C. & Chien, L.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Computational analysis of gene expression profiles and genetic polymorphisms to predict the risk of osteoporosis

  Chang, W.

  1/1/15 → 12/31/15

  Project: C - Project of Alliance › j - National Taipei University of Technology

• Preclinical evaluation of novel selective HDAC6 inhibitors for human cancers treatment

  Pan, S.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • ricolinostat 100%
  • Neoplasms 97%
  • Heterografts 90%
  • Investigational New Drug Application 86%
  • Pharmaceutical Preparations 62%

• 臺北醫學大學附設醫院之疾病個案收集與建立臺灣人體生物資料庫

  Yen, Y.

  1/1/15 → 12/31/15

  Project: A - Government Institution › f - Other (Funded by Government)

• TMU103-AE1-B12

  Lee, K.

  1/1/15 → 12/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty