TMU Research Center of Cancer Translational Medicine

Projects

Projects per year 2010 2014 2015 2016 2017 2018 2022

• 5 Active
• 531 Finished

Projects per year

Search results

• Finished

  Application of High-Throughput Sequencing Approaches in Immunogenomic Research : Diversity and Clonal Selection in the Human T-Cell Repertoire for Colonrectal Cancers(3/4)

  Chang, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Hmga2-Microrna Regulatory Network to Tune Oncogenesis

  Huang, T.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • MicroRNAs 16%
  • Colorectal Neoplasms 12%
  • Carcinogenesis 9%
  • Neoplasms 7%

• Identifying Cancer-Stem-Cell-Invadopodia-Related Prognostic Biomarkers in Gastric Cancer

  Chan, T.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Podosomes 100%
  • Neoplastic Stem Cells 71%
  • Stomach Neoplasms 27%
  • Neoplasms 18%
  • Neoplasm Metastasis 11%

• Functional Study of a Novel Long Non-Coding Rna Linat in Colorectal Cancer Progression(2/3)

  Chen, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Mass Spectrometry-Based Quantification Strategies for Onco-Proteogenomics Investigation of Cancer-Specific Mutated Proteins (2nd~3rd Year)

  Han, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mutation 100%
  • Proteogenomics 74%
  • Mass Spectrometry 70%
  • Proteins 49%
  • Peptides 35%

• A Translational Investigation of the Role of Myc/Pd-L1/Akt Axis as a Therapeutic Target for Treating Glioblastoma Multiforme

  Lin, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Cross-Talk between Endothelial Cell-Specific Molecule-1 (Esm1) and Epidermal Growth Factor Receptor (Egfr) in the Progression of Non-Small-Cell Lung Cancer (Nsclc)(1/3)

  Chien, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatitis B virus 100%
  • Hepatocellular Carcinoma 65%
  • Hep G2 Cells 23%
  • Hepatitis B 21%
  • Neoplasms 19%

• Development of Novel Dyrk1a Inhibitors for the Treatment of Alzheimer'S Disease

  HuangFu, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dyrk kinase 100%
  • Alzheimer Disease 43%
  • Neurofibrillary Tangles 17%
  • Amyloid beta-Peptides 15%
  • Memory 10%

• To Develop Novel Treatment Options for Hepatocellular Carcinoma via Drug Repurposing(1/2)

  Whang-Peng, J.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Mirna and Gut Microbiota in Pathogenesis of Post-Stroke Vascular Cognitive Impairment

  Chiou, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Ribonucleotide Reductase (Rnr) in Skeletal Muscle with Age: the Functionality of Rrm2b in Repair and Regeneration

  Chen, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skeletal Muscle 100%
  • Sarcopenia 58%
  • Regeneration 52%
  • Muscles 47%
  • Muscular Diseases 33%

• Nano-Diamino-Tetrac (Ndat) Enhances Resveratrol-Induced Anti-Proliferation by Action on the Rrm2 Pathway in Colorectal Cancers

  Lin, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Resveratrol 100%
  • Ribonucleotide 49%
  • Antiproliferative 13%
  • Bellow 10%
  • Stilbenoid 10%

• Role of Niche Inflammatory Cytokine and Epigenetic Regulation in Expressions of Pluripotent Transcription Factor Oct4 and Sorafenib Refractoriness in Hbv-Related Hepatocellular Carcinoma and Its Clinical Implication.(I)(1/3)

  Huang, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Mechanisms of Dna Primase（Prim1）Involved in Smoking-Induced Breast Cancer Formations and Its Translational Applications

  Chen, L.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Angiopoietin-Like Protein 1 in Sorafenib Resistance and Cancer Stemness of Hepatocellular Carcinoma Cells

  Huang, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Angiopoietin-like Proteins 100%
  • Sorafenib 97%
  • Hepatocellular Carcinoma 53%
  • Gastropoda 44%
  • Neoplasms 17%

• Generate Anti-Fibroblast Growth Factor Receptor 2 (Fgfr2) Antibody Drugs and Study on Their Potential Application against Gastric Cancer

  Lee, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Anti-Egfr×Anti-Fap Bi-Specific Targeting Antibody Combined with Irinotecan Encapsulated Liposomes for Pancreatic Cancer Therapy

  Lin, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Therapeutic Potentials of Exosomes from Mesenchymal Stem Cell on Mitigating Cardiac Alterations and Their Effects on Modulating Oxidation, Inflammation, Mitochondrial Dysfunction and Insulin Resistance in Obesity Mice and Obesity Mice with Sepsis

  Huang, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role and Molecular Mechanisms of N-Α-Acetyltransferase in Driving Tumor Invasion and Metastasis of Osteosarcoma(3/3)

  Chien, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteosarcoma 100%
  • gelatinase A 66%
  • metastasis 59%
  • neoplasms 30%
  • acetyltransferases 21%

• Dissected the Role of Thrombomodulin in the Clinical Diagnostic and Therapeutic Impacts for Breast Cancer and the Regulation Mechanisms(3/3)

  Hung, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thrombomodulin 100%
  • Breast Neoplasms 90%
  • Therapeutics 20%
  • Neoplasms 12%
  • Steroid Receptors 11%

• Involvement of Genes Encoding Apoptosis Regulatory Pathway in the Pathogenesis of Hyperglycemia in Acute Ischemic Stroke

  Hsieh, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Environmental Factors and Genetic Polymorphisms Associate with the Development and Prognosis of Oral Squamous Cell Carcinoma

  Yeh, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Squamous Cell Carcinoma 100%
  • Genes 26%
  • Taiwan 21%
  • DNA Repair 20%
  • Genome 14%

• Deciphering the Mechanisms of Multiple Myeloma Tumor Driving Factor Whsc1 in Kras Mutated Colon Cancer Progression and Investigate the Whsc1 Targeting Combination Therapy

  Cho, E.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colonic Neoplasms 100%
  • Fluorouracil 18%
  • Oxaliplatin 15%
  • Multiple Myeloma 12%
  • Drug Resistance 11%

• Study of the Angiogenesis Promoting Effect of Irradiation Induced Mir-17-5p in Oral Cancer Cells

  Wu, S.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mouth Neoplasms 100%
  • Neoplasms 51%
  • Angiogenesis Inducing Agents 51%
  • Angiogenesis Inhibitors 27%
  • Cell Culture Techniques 26%

• Molecular Mechanisms of Secretory Rab Gtpase 3c in Promoting Colon Cancer Metastasis

  Chen, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Role of Adam17/Preadipocyte Factor-1 in Hypoxia-Induced Ctgf Expression and Airway Fibrosis(1/3)

  Chen, B.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新聘教師研究補助

  Huang, Y.

  8/1/18 → 7/31/19

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• The Role of Sp1-Regulated Neurosteroidogenesis in Glioma Development(2/2)

  Hsu, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neurosteroids 100%
  • Glioma 74%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Astrocytes 34%

• 探討腸道菌相在抗精神病藥物誘發思覺失調症患者代謝症候群之作用

  Liu, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Gastrointestinal Microbiome 100%
  • Antipsychotic Agents 61%
  • Schizophrenia 41%
  • Treatment Adherence and Compliance 38%
  • Metabolic Diseases 35%

• A Translational Study to Verify Roles of Circulating Mir-19b and Mir-93 as Biomarker Signatures for Early Diagnosis of Osteoporosis in Men

  Chen, R.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Oncogenic Roles of A9-Nicotinic Acetylcholine Receptor Variants on Breast Cancer(II)(2/3)

  Ho, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• PRIM1為乳癌標靶治療之細胞與動物模式分析

  Chen, L.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討miR-296-5p/Pin1/XPO5調控與大腸直腸癌相關之oncomiRs的表現

  Lee, K.

  3/1/18 → 3/31/19

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 心血管疾病防治照護試辦計畫-分項二：建構以個案為中心的社區心血管疾病防治模式

  Chen, L.

  2/26/18 → 3/20/18

  Project: A - Government Institution › f - Other (Funded by Government)

• 新聘教師研究補助

  Chan, T.

  1/15/18 → 1/14/19

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 新聘教師研究補助

  Hsieh, T.

  1/1/18 → 12/31/18

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 探討代謝重整、非編碼核糖核酸與腫瘤抑制因子之相互作用對胰臟癌Gemcitabine抗藥性的影響及其在轉譯醫學上的應用：鑑定腫瘤分子機制與找尋具潛力之治療標靶

  Huang, M.

  1/1/18 → 12/31/18

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 新聘教師研究補助

  Shiah, H.

  1/1/18 → 12/31/18

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 亞太生醫矽谷精準醫療旗艦計畫-臺北醫學大學合作案

  Yen, Y.

  1/1/18 → 12/31/18

  Project: A - Government Institution › a - National Health Research Institutes

• 106-107年預防保健服務行政事務管理計畫-107年後續擴充

  Chiou, H.

  1/1/18 → 12/31/18

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 長鏈非編碼核糖核酸LncHIFCAR/MIR31HG調控的中心網絡在胰臟癌的轉譯研究

  Lee, K.

  1/1/18 → 12/31/18

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 青少年世代健康行為長期追蹤研究計畫(106-108年)-107年度後續擴充

  Chiou, H.

  1/1/18 → 12/31/18

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Artificial Intelligence for Earlier and Safer Medicine Worldwide( I )

  Li, Y.

  1/1/18 → 12/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Medicine 100%
  • Artificial intelligence 61%
  • Electronic medical equipment 26%
  • Compliance 17%
  • Aging of materials 15%

• 探討ZBTB46在神經內分泌前列腺癌抗藥性之分子機轉及治療研究

  Liu, Y.

  1/1/18 → 12/31/18

  Project: A - Government Institution › a - National Health Research Institutes

• 新聘教師研究補助

  Huang, C.

  1/1/18 → 12/31/18

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 106年度委託科技研究計畫－「智慧醫療之環境整備與試行」分項6：「有效運用人工智慧於我國及國際醫療服務之研究」

  Li, Y.

  12/29/17 → 8/28/18

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Artificial intelligence 100%
  • Health care 31%
  • Medicine 20%
  • Medical information systems 15%
  • Smart sensors 12%

• ICT於國人健康監測暨個人健康風險評測與健康管理之應用

  Chiou, H.

  12/26/17 → 12/25/18

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 子宮內膜癌分子篩檢試劑套組開發案

  Lai, H.

  12/1/17 → 5/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 臺北醫學大學自有貴重儀器共用服務計畫

  Lin, S.

  12/1/17 → 12/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology