TMU Research Center of Cancer Translational Medicine

Projects

Projects per year 2010 2014 2015 2016 2017 2018 2022

• 5 Active
• 531 Finished

Projects per year

Search results

• Dissected the Role of Thrombomodulin in the Clinical Diagnostic and Therapeutic Impacts for Breast Cancer and the Regulation Mechanisms

  Hung, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thrombomodulin 100%
  • Breast Neoplasms 90%
  • Therapeutics 20%
  • Neoplasms 12%
  • Steroid Receptors 11%

• Studies on the Carcinogenic Mechanisms of Glucose Transporters in Gastrointestinal Cancer Cells and Its Clinical Therapeutic Applications(2/2)

  Chen, L.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glucose 100%
  • Antitumor 19%
  • Occurrence in Nature 17%
  • Pharmacological Metabolism 11%
  • Biological Role 8%

• Study the Role and Regulation of Dicer in Sorafenib Sensitivity of Liver Cancer

  Chen, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sorafenib 100%
  • Liver Neoplasms 86%
  • Hepatocellular Carcinoma 28%
  • MicroRNAs 14%
  • Neoplasms 13%

• ORMDL3在thrombin誘導IL-8/CXCL8表現及呼吸道發炎之角色探討(3/3)

  Chen, B.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orosomucoid 100%
  • Thrombin 74%
  • Interleukin-8 34%
  • Transcription Factor AP-1 26%
  • Asthma 23%

• Identification and Characterization of Ddx3 Downstream Epithelial-Mesenchymal Transition (Emt) Targets in Colorectal Cancer Metastasis

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epithelial-Mesenchymal Transition 100%
  • Neoplasm Metastasis 95%
  • Colonic Neoplasms 87%
  • Snails 47%
  • RNA 40%

• Epigenetic Editing as a Novel Therapeutics for Gynecological Cancer

  Lai, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epigenomics 100%
  • Clustered Regularly Interspaced Short Palindromic Repeats 43%
  • Tumor Biomarkers 27%
  • Neoplasms 24%
  • Gene Editing 23%

• Establishing the Disease and Genetic Risk Prediction Score of Cognitive Impairment to Early Prevent the Threat of Dementia

  Hsieh, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dementia 100%
  • Neurodegenerative Diseases 80%
  • Iron-Deficiency Anemias 78%
  • Taiwan 65%
  • Cognitive Dysfunction 65%

• Disease trajectories and its association with metabolic dysfunction of prostate cancer men following androgen deprivation therapy and the potential of pharmacological medication in preventing metastatic diseases.(2/3)

  Shao, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Androgens 100%
  • Prostatic Neoplasms 60%
  • Hyperlipidemias 44%
  • Taiwan 43%
  • Metabolic Syndrome 30%

• The Association of Nonage Chronic Arsenic Exposure, Methylation Levels of Arsenic Metabolism Genes, and the Risk of Cancer Development(2/3)

  Chiou, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • arsenic 100%
  • adulthood 37%
  • neoplasms 27%
  • methylation 24%
  • metabolism 15%

• 顱內靜脈血管系統異常與缺血性中風及皮質下血管性失智症的相關性研究

  Chiou, H.

  8/1/16 → 7/31/17

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Studies on the Mechanisms of Histamine N-Methyltransferase (Hnmt)-Mediated Herceptinr Drug-Resistance in Breast Cancer Cells

  Ho, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Trastuzumab 89%
  • Breast Neoplasms 17%
  • Tissue Array Analysis 9%
  • Gene Expression Profiling 8%

• 轉譯醫學研究法探討茶緩解菸害之機轉:乳癌和動脈粥狀硬化為例(3/3)

  Ho, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tea 100%
  • Nicotine 28%
  • Capsules 25%
  • Breast Neoplasms 21%
  • MicroRNAs 19%

• HMGA2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers(2/3)

  Lin, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 75%
  • tetraiodothyroacetic acid 70%
  • Colorectal Neoplasms 43%
  • Integrins 28%

• Combination Treatment of Tetrac- and Cetuximab-Induced Anti-Proliferation in Colorectal Cancer with Different Apc Status( III )

  Lin, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of Regioselective Substitution on 1,4-Benzoquinone Derivatives to Provide Potent Anticancer Agents(3/3)

  Liou, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1,4-benzoquinone 100%
  • Wittig Olefination 54%
  • Intramolecular Cyclization 40%
  • Nucleophilic Substitution 38%
  • Regioselectivity 35%

• 組織胺甲基化轉移酵素於腸癌致癌機制探討

  Chen, L.

  6/1/16 → 5/31/17

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 探討透過黑殭菌素B調控Nrf2/KEAP1在對於三陰性乳癌治療效果之轉譯研究

  Wu, S.

  6/1/16 → 5/31/17

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 探討透過黑殭菌素B調控Nrf2/KEAP1在對於三陰性乳癌治療效果之轉譯研究

  Wu, S.

  5/31/16 → 5/30/17

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 104-105年預防保健服務專案管理計畫-105年後續擴充

  Chiou, H.

  3/12/16 → 3/11/17

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 緩激肽調控惡性神經膠瘤細胞基質金屬蛋白酶-13 表現和影響血瘤障壁通透性之研究

  Chen, R.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 將生物資訊之方法和功能性研究應用於基因表達與乳癌危險性相關性

  Chang, W.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › q - Cathay General Hospital

• N-methyl-D-aspartate receptor調控血腦障壁之角色探討

  Chen, R. & Wu, G.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• The role of miR-203 and miR-34a in EGFR activation prostate cancer metastasis

  Liu, Y.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Prostatic Neoplasms 100%
  • Genes 42%
  • Neoplasm Metastasis 17%
  • Phenotype 11%
  • Bone and Bones 11%

• 醫院所有權結構是否會影響醫院生產力與品質表現

  Chien, L.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › l - National Taiwan Ocean University

• 鱘龍魚軟骨萃取物於延緩老化之臨床前研究與產品開發

  Deng, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › e - Council of Agriculture

• Social medicine discipline research Planning and Promotion project

  Chiou, H.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of DNA methylation biomarker for endometrial cancer detection

  Lai, H.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Endometrial Neoplasms 100%
  • Methylation 31%
  • Myoma 17%
  • Genes 14%
  • Taiwan 13%

• 105年度第二期癌症研究計畫-臺北醫學大學

  Yen, Y., Whang-Peng, J., Liu, L. & Chang, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Neoplasms 100%
  • Breast Neoplasms 76%
  • Antibodies 52%
  • Computational Biology 40%
  • Nicotine 34%

• 合成選擇性HDAC6?抑制劑

  Liou, J.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 癌症早期發現相關策略研究－分癌別評估癌症篩檢執行人力與未來發展之需求：乳癌、子宮頸癌、大腸癌、口腔癌與肝癌(105年)

  Chen, L. & Wang, S.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Establishing Health and Welfare Biotechnology Electronic Database Sharing Platform, Promoting Evidence-Based Medicine and Disseminating Technology Knowledge in Taiwan

  Chen, C., Tam, K., Chen, K., Hou, W. & Bai, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Healthcare 100%
  • evidence 76%
  • welfare 56%
  • ministry 47%
  • health 44%

• 失眠患者之睡前準備穿戴式雲平台系統開發與驗證

  Li, Y.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• 新聘教師研究補助

  Chen, L.

  1/1/16 → 12/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Preclinical evaluation of novel selective HDAC6 inhibitors for human cancers treatment

  Pan, S.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Mesylates 100%
  • ricolinostat 43%
  • Heterografts 39%
  • Investigational New Drug Application 37%
  • Outsourced Services 35%

• In vitro, ex vivo and clinical characterization of novel Salmonella virulence genes

  Fang, S. & Huang, M.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Salmonella 100%
  • Virulence 62%
  • Salmonella Infections 59%
  • Salmonella typhimurium 54%
  • Genes 47%

• 臺北醫學大學附設醫院之疾病個案收集與建立臺灣人體生物資料庫

  Yen, Y.

  1/1/16 → 12/31/16

  Project: A - Government Institution › f - Other (Funded by Government)

• 設計診斷治療型之鄰脂質奈米粒子於放射型治療上之研究

  Wu, S.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• 高功率奈米製程之摻鉺光纖雷射在皮膚分段光熱分解療法之應用

  HuangFu, W.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › j - National Taipei University of Technology

• Epigenetic Characterization of Ovarian Cancer Initiating Cells

  Lai, H.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Ovarian Neoplasms 100%
  • Neoplastic Stem Cells 64%
  • Epigenomics 43%
  • 5-hydroxymethylcytosine 16%
  • Stem Cell Research 14%

• Evaluation on prevention for metabolic syndrome and diabetes mellitus through lifestyle modification intervention in pre-diabetic subjects (100-104)

  Chiou, H.

  12/31/15 → 12/30/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 104年度科學及技術類委託研究計畫「健保已給付新藥副作用之風險評估_以口服抗凝血劑為例」計畫案

  Chien, L., Ko, Y., Chien, S. & Chi, N.

  12/23/15 → 12/22/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Service for Sharing Precious Instruments of Taipei Medical University

  Chen, Y., Liou, J. & Chien, L.

  12/1/15 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Reservation systems 100%
  • Mass spectrometers 91%
  • Nuclear magnetic resonance 77%
  • Magnetic resonance spectrometers 60%
  • Online systems 38%

• 新北市醫療照護資源垂直整合模式成效評估計畫

  Chiou, H.

  10/22/15 → 7/11/16

  Project: A - Government Institution › f - Other (Funded by Government)

• Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases --Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (II)

  Huang, Y.

  10/1/15 → 9/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Phase I, First-In-Human, Dose-Seeking Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Orally Administered MPT0E028 in Subjects with Advanced Solid Malignancies without Standard Treatment (II)

  Liou, J.

  9/1/15 → 8/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Carcinogenic Mechanisms of Glucose Transporters in Gastrointestinal Cancer Cells and Its Clinical Therapeutic Applications

  Chen, L. & Wu, C.

  9/1/15 → 8/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glucose 100%
  • Antitumor 19%
  • Occurrence in Nature 17%
  • Pharmacological Metabolism 11%
  • Biological Role 8%

• 建立多構面癌症防治預測模式:以大腸癌為例－建立多構面癌症防治預測模式:以大腸癌為例

  Shao, Y.

  9/1/15 → 8/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of EGFR in Prostate Cancer Progression and Combination Therapy

  Liu, Y. & Chen, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • ErbB Receptors 82%
  • Berberis 26%
  • Neoplastic Stem Cells 16%
  • Neoplasms 15%

• Role of miR-21 in Regulating TET I-Hydroxymethylcytosine and Chemotherapeutic Response in Colorectal Cancer (II)

  Yang, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Roles of Genetic Polymorphisms for Susceptibility and Clinical Outcomes of Colorectal Cancer in Taiwanese Lynch Syndrome Families

  Yeh, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hereditary Nonpolyposis Colorectal Neoplasms 100%
  • DNA Mismatch Repair 57%
  • Colorectal Neoplasms 54%
  • Genetic Polymorphisms 29%
  • Genes 19%