TMU Research Center of Cancer Translational Medicine

Projects

Projects per year 2010 2014 2015 2016 2017 2018 2022

• 5 Active
• 531 Finished

Projects per year

Search results

• 高功率奈米製程之摻鉺光纖雷射在皮膚分段光熱分解療法之應用

  HuangFu, W.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › j - National Taipei University of Technology

• Preclinical evaluation of novel selective HDAC6 inhibitors for human cancers treatment

  Pan, S.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Mesylates 100%
  • ricolinostat 43%
  • Heterografts 39%
  • Investigational New Drug Application 37%
  • Outsourced Services 35%

• 合成選擇性HDAC6?抑制劑

  Liou, J.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• The role of miR-203 and miR-34a in EGFR activation prostate cancer metastasis

  Liu, Y.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Prostatic Neoplasms 100%
  • Genes 42%
  • Neoplasm Metastasis 17%
  • Phenotype 11%
  • Bone and Bones 11%

• 設計診斷治療型之鄰脂質奈米粒子於放射型治療上之研究

  Wu, S.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• 臺北醫學大學附設醫院之疾病個案收集與建立臺灣人體生物資料庫

  Yen, Y.

  1/1/16 → 12/31/16

  Project: A - Government Institution › f - Other (Funded by Government)

• 新聘教師研究補助

  Chen, L.

  1/1/16 → 12/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 105年度第二期癌症研究計畫-臺北醫學大學

  Yen, Y., Whang-Peng, J., Liu, L. & Chang, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Neoplasms 100%
  • Breast Neoplasms 76%
  • Antibodies 52%
  • Computational Biology 40%
  • Nicotine 34%

• 失眠患者之睡前準備穿戴式雲平台系統開發與驗證

  Li, Y.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• Social medicine discipline research Planning and Promotion project

  Chiou, H.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 醫院所有權結構是否會影響醫院生產力與品質表現

  Chien, L.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › l - National Taiwan Ocean University

• In vitro, ex vivo and clinical characterization of novel Salmonella virulence genes

  Fang, S. & Huang, M.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Salmonella 100%
  • Virulence 62%
  • Salmonella Infections 59%
  • Salmonella typhimurium 54%
  • Genes 47%

• Establishing Health and Welfare Biotechnology Electronic Database Sharing Platform, Promoting Evidence-Based Medicine and Disseminating Technology Knowledge in Taiwan

  Chen, C., Tam, K., Chen, K., Hou, W. & Bai, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Healthcare 100%
  • evidence 76%
  • welfare 56%
  • ministry 47%
  • health 44%

• 鱘龍魚軟骨萃取物於延緩老化之臨床前研究與產品開發

  Deng, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › e - Council of Agriculture

• N-methyl-D-aspartate receptor調控血腦障壁之角色探討

  Chen, R. & Wu, G.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 將生物資訊之方法和功能性研究應用於基因表達與乳癌危險性相關性

  Chang, W.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › q - Cathay General Hospital

• 緩激肽調控惡性神經膠瘤細胞基質金屬蛋白酶-13 表現和影響血瘤障壁通透性之研究

  Chen, R.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 104-105年預防保健服務專案管理計畫-105年後續擴充

  Chiou, H.

  3/12/16 → 3/11/17

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 探討透過黑殭菌素B調控Nrf2/KEAP1在對於三陰性乳癌治療效果之轉譯研究

  Wu, S.

  5/31/16 → 5/30/17

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 探討透過黑殭菌素B調控Nrf2/KEAP1在對於三陰性乳癌治療效果之轉譯研究

  Wu, S.

  6/1/16 → 5/31/17

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 組織胺甲基化轉移酵素於腸癌致癌機制探討

  Chen, L.

  6/1/16 → 5/31/17

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• ADAM9 調節 integrin b4 之轉換率以促使前列腺癌細胞移動及浸潤之研究(3/3)

  Sung, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • metastasis 100%
  • integrins 89%
  • neoplasm progression 42%
  • neoplasms 38%
  • neoplasm cells 32%

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatitis B virus 100%
  • Hepatocellular Carcinoma 65%
  • Hep G2 Cells 23%
  • Hepatitis B 21%
  • Neoplasms 19%

• The Role of EGFR in Prostate Cancer Progression and Combination Therapy(2/3)

  Liu, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • ErbB Receptors 82%
  • Berberis 26%
  • Neoplastic Stem Cells 16%
  • Neoplasms 15%

• Study the Role and Regulation of Dicer in Sorafenib Sensitivity of Liver Cancer

  Chen, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sorafenib 100%
  • Liver Neoplasms 86%
  • Hepatocellular Carcinoma 28%
  • MicroRNAs 14%
  • Neoplasms 13%

• Epigenetic Editing as a Novel Therapeutics for Gynecological Cancer

  Lai, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epigenomics 100%
  • Clustered Regularly Interspaced Short Palindromic Repeats 43%
  • Tumor Biomarkers 27%
  • Neoplasms 24%
  • Gene Editing 23%

• The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells.( II )

  Yen, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 幹細胞基礎研究與前臨床動物試驗

  Huang, Y.

  8/1/16 → 7/31/17

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Pharmacological Role of a Novel Dual-Targeting Hdacs/Microtubule Inhibitor 21-277 Inhibits Human Cancer Cells Growth in Vitro and in Vivo

  HuangFu, W.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone 100%
  • Antineoplastic Agent 99%
  • Pharmacological Role 34%
  • Protein 23%
  • Growth Inhibition 22%

• Role and Molecular Mechanisms of N-Α-Acetyltransferase in Driving Tumor Invasion and Metastasis of Osteosarcoma

  Chien, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteosarcoma 100%
  • gelatinase A 66%
  • metastasis 59%
  • neoplasms 30%
  • acetyltransferases 21%

• Combination Treatment of Tetrac- and Cetuximab-Induced Anti-Proliferation in Colorectal Cancer with Different Apc Status( III )

  Lin, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• 不同APC基因狀態大腸直腸癌患者藥物治療之抗藥性機轉研究-探討miR-21調控大腸直腸癌細胞TET1/5-hydroxymethylcytosine表現對其化療反應之關聯(3/3)

  Yang, P.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Ribonucleotide Reductase (Rnr) in Skeletal Muscle with Age: the Functionality of Rrm2b in Repair and Regeneration

  Chen, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skeletal Muscle 100%
  • Sarcopenia 58%
  • Regeneration 52%
  • Muscles 47%
  • Muscular Diseases 33%

• 轉譯醫學研究法探討茶緩解菸害之機轉:乳癌和動脈粥狀硬化為例(3/3)

  Ho, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tea 100%
  • Nicotine 28%
  • Capsules 25%
  • Breast Neoplasms 21%
  • MicroRNAs 19%

• 新穎微管陣列薄膜(MTAM)應用於抗癌藥物轉譯運用 / 快速個人化之體內抗癌藥物篩選平台技術之建立與臨床確效

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification and Characterization of Ddx3 Downstream Epithelial-Mesenchymal Transition (Emt) Targets in Colorectal Cancer Metastasis

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epithelial-Mesenchymal Transition 100%
  • Neoplasm Metastasis 95%
  • Colonic Neoplasms 87%
  • Snails 47%
  • RNA 40%

• Investigation of B-Cell Activating Factor Expression and Its Role in Radiationenteritis

  Wu, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Enteritis 100%
  • Radiation 66%
  • Animal Models 29%
  • Neutralizing Antibodies 24%
  • B-Cell Activating Factor 23%

• Research of Carbon Nanomaterials Conjugated with Raf Kinase Inhibitors as Multifunctional Delivery System for Kras Mutated Colorectal Cancer Treatment

  Cho, E.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanomaterial 100%
  • Phosphotransferase Inhibitor 75%
  • Carbon Atom 74%
  • Drug 63%
  • Folic Acid 23%

• Development a Risk Scoring System for Predicting the Risk of Poststroke Epilepsy to Improve the Quality of Care among Patients with Stroke

  Chien, L.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epilepsy 100%
  • Stroke 45%
  • Anticonvulsants 24%
  • National Health Programs 20%
  • University Hospitals 15%

• Disease trajectories and its association with metabolic dysfunction of prostate cancer men following androgen deprivation therapy and the potential of pharmacological medication in preventing metastatic diseases.(2/3)

  Shao, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Androgens 100%
  • Prostatic Neoplasms 60%
  • Hyperlipidemias 44%
  • Taiwan 43%
  • Metabolic Syndrome 30%

• 新穎性pan-HDAC 抑制劑抑制血管新生之藥物研發與藥理作用機轉(3/3)

  Pan, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase Inhibitors 100%
  • Histone Deacetylases 49%
  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 20%
  • Animal Models 18%
  • Drug Discovery 17%

• The Role of Wnt5a and Hsp90 in the Wnt/Beta-Catenin Signaling Pathway of Colorectal Cancer( III )

  Lee, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討骨髓間質幹細胞在前列腺癌引發的骨重塑的生物功能與作用機制(3/3)

  Hsieh, C.

  8/1/16 → 8/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipogenic 100%
  • Osteogenic 37%

• Dissected the Role of Thrombomodulin in the Clinical Diagnostic and Therapeutic Impacts for Breast Cancer and the Regulation Mechanisms

  Hung, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thrombomodulin 100%
  • Breast Neoplasms 90%
  • Therapeutics 20%
  • Neoplasms 12%
  • Steroid Receptors 11%

• The Role of Angiopoietin-Like Protein 1 in Sorafenib Resistance and Cancer Stemness of Hepatocellular Carcinoma Cells

  Huang, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Angiopoietin-like Proteins 100%
  • Sorafenib 97%
  • Hepatocellular Carcinoma 53%
  • Gastropoda 44%
  • Neoplasms 17%

• Study the Function and Regulation of Mirnas in Pancreatic Cancer Progression( III )

  Huang, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of Regioselective Substitution on 1,4-Benzoquinone Derivatives to Provide Potent Anticancer Agents(3/3)

  Liou, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1,4-benzoquinone 100%
  • Wittig Olefination 54%
  • Intramolecular Cyclization 40%
  • Nucleophilic Substitution 38%
  • Regioselectivity 35%

• The Impacts of Obesity-Associated Alterations in Adipose-Derived Stem Cell on Tumor Development

  Deng, W.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Obesity 100%
  • Stem Cells 94%
  • Neoplastic Stem Cells 60%
  • Neoplasms 41%
  • Mesenchymal Stem Cells 38%

• Targeting Class III Phosphoinositide 3-Kinase (Pi3k) for Anticancer Drug Discovery

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphoinositide 100%
  • 3-Methyladenine 41%
  • Antineoplastic Agent 32%
  • Protein Synthesis 25%
  • LY294002 22%