TMU Research Center of Cancer Translational Medicine

Projects

Projects per year 2010 2014 2015 2016 2017 2018 2022

• 5 Active
• 531 Finished

Projects per year

Search results

• 病毒性肝炎高盛行地區非酒精性脂肪肝疾病的盛行率與發生率風險因子

  Chen, L.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 探討propofol減緩敗血症傷害的機轉: 轉譯醫學研究

  Chen, R.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 使用超音波導引腹橫肌平面神經阻斷術於減重手術後之止痛作用

  Tam, K.

  3/1/15 → 6/30/16

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 探討細胞自噬在低氧調控多型性神經膠母細胞瘤生成過程所扮演的角色

  Chen, R.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 104-105年預防保健服務專案管理計畫

  Chiou, H.

  3/12/15 → 3/11/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• A cohort study of chronic kidney disease (the 101th-104th year of the Republic Era)

  Lin, Y., Chiou, H., Hsu, Y., Wu, M., Hsieh, F., Bai, C., Hsieh, Y., Chien, L., Wang, Y., Wu, M., Yang, S., Lin, Y. & Lin, C.

  3/31/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Chronic Renal Insufficiency 100%
  • Taiwan 77%
  • Chronic Kidney Failure 68%
  • Annual Reports 21%
  • Data Systems 19%

• TMU103-AE1-B19

  Lee, Y.

  4/1/15 → 3/31/16

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Evaluate and Engineer Anti-Fibroblast Growth Factor Receptor 2 (Fgfr2) Antibody Drugs and Study on Their Potential Application against Cancer

  Lee, Y.

  4/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibroblast Growth Factor Receptors 100%
  • Stomach Neoplasms 23%
  • Antibodies 21%
  • Receptor, Fibroblast Growth Factor, Type 2 16%
  • Neoplasms 16%

• 建構領航國際之活躍老化監測暨決策支援系統-活躍老化資料倉儲與決策支援系統(104-107年)之需求規劃暨監造管理計畫

  Liu, C., Yeh, Y., Chiou, H. & Chi, M.

  4/30/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 探討Hsp27在大腸癌的進行、轉移能力與治療上的角色及其作用機制

  Wei, P.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 葡萄糖轉運受體於腸胃肝癌致癌作用與治療之探討

  Chen, L.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 探討TSA透過抑制YAP1訊息傳導作為治療抗藥性胰臟癌之潛力藥物

  Wu, S.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 探討乳酸去氫?對胰臟癌Gemcitabine抗藥性的調控與影響

  Huang, M.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 退黑激素對於腎細胞癌侵犯轉移之療效及其相關調控機轉探討

  Chien, M.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 探討腫瘤抑制分子FOXO3a在胰臟癌gemcitabine抗藥性的角色

  Chen, H.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 卵巢癌幹細胞之代謝研究-I奉

  Lai, H.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 從染色體中心節蛋白(CENP)家族中找尋可以用來當作卵巢癌的新腫瘤標的

  Lee, K.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 探討Androgen receptor調控WNT 訊號傳遞在攝護腺癌之作用機轉

  Liu, Y.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 以深度蛋白體分析探討非小細胞肺癌病人骨髓源生抑制性細胞與肺癌細胞在藥物治療下之交互作用機制

  Han, C.

  5/1/15 → 12/31/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• TGF-beta誘導人類肺癌細胞JARID2表現之機轉研究

  Chen, B.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 運用化學基因體學方法開發新穎核糖核?酸還原?抑制劑用以治療大腸直腸癌

  Yang, P.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 篩選一個具有保護神經而且可能發展為腦創傷治療藥物的Sigma 1受體促效劑

  Chuang, J.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 探討缺氧環境中透過Hif-2α支配的Igf-1r—Cxcr4訊號迴路調控小鼠生殖系幹細胞爬行作用機制

  Huang, Y.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 探討integrin αvβ3及EGFR間交叉效應對於甲狀腺賀爾蒙誘發大腸直腸癌細胞增生作用之影響

  Lin, H.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• EGFR反式活化依賴NADPH oxidase/ROS/NF-kB路徑媒介thrombin誘導肺部上皮細胞IL-8/CXCL8表現之探討

  Chen, B.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 104年度「委託科技研究計畫--以資通訊科技提升照護品質」分項計畫5：長期照護服務導入資通訊科技之策略規劃

  Yen, Y., Chiou, H., Liu, C. & Lin, P.

  6/12/15 → 2/11/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Long-term Care 100%
  • Taiwan 24%
  • System Development 22%
  • Needs Assessment 18%
  • Managers 16%

• 雲林縣整合性社區健康篩檢工作成果評價分析計畫案

  Chen, L.

  6/18/15 → 12/10/15

  Project: A - Government Institution › f - Other (Funded by Government)

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-6 100%
  • Hepatocellular Carcinoma 94%
  • Hypoxia 55%
  • Drug Resistance 32%
  • Neoplasms 30%

• Drug Discovery and Pharmacological Study of Novel pan-HDAC Inhibitors as Anti-Angiogenic Drugs

  Pan, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase Inhibitors 100%
  • Histone Deacetylases 36%
  • Drug Discovery 23%
  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 18%
  • Animal Models 16%

• Pre-Clinical Evaluation of the Tumor Suppression Effectiveness and Mechanism of Small Molecule Drugs in Oral Cancer

  Chen, Y. & Wu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pharmaceutical Preparations 100%
  • Mouth Neoplasms 70%
  • Pharmaceutical Databases 22%
  • Neoplasm Genes 17%
  • Biological Products 15%

• Study the Therapeutic Effects and Novel Molecular Mechanisms of Resveratrol in Human Osteosarcoma---The Treatment of Metastatic Cancer

  Chien, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Resveratrol 100%
  • MicroRNA 72%
  • Microarrays 10%
  • Non Toxic 10%
  • Dose 7%

• Dissected the Role of Glucose-Regulated Protein 94 (GRP94),The Clinically Therapeutic Implication and Drug Development in Colon Cancer

  Wei, P. & Chang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • glucose-regulated proteins 100%
  • Colonic Neoplasms 43%
  • Colorectal Neoplasms 38%
  • Neoplasms 23%
  • Neoplasm Metastasis 19%

• A Toxicological Assessment of Air Pollution in the Vicinity of a Petrochemical Complex

  Chuang, H. & Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Particulate Matter 100%
  • Taiwan 54%
  • Toxicology 44%
  • Risk Assessment 38%
  • Methionine 19%

• The Measure of Palliative Care Spiritual Care Competency and the Effectiveness of an Educational Program for Palliative Spiritual Care Providers

  Chiou, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Palliative Care 100%
  • Program Evaluation 46%
  • Education 32%
  • Research Design 24%
  • Learning 15%

• Study the Function and Regulation of miRNAs in Pancreatic Cancer Progression (II)

  Huang, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells (I)

  Yen, Y., Cheng, T. & Wu, A. T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Leukemia 100%
  • haptoglobin-hemoglobin complex 54%
  • Calicheamicins 53%
  • Neoplasms 49%
  • Multifunctional Nanoparticles 49%

• Effects of Uteroplacental Insufficiency and Hyperoxia on Lung Development and Epigenetic Alterations in the Rat Offspring

  Chen, C. & Lin, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fetal Growth Retardation 100%
  • Hyperoxia 99%
  • Receptor for Advanced Glycation End Products 74%
  • Epigenomics 69%
  • Lung 48%

• Role of miR-21 in Regulating TET I-Hydroxymethylcytosine and Chemotherapeutic Response in Colorectal Cancer (II)

  Yang, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effect and Mechanisms of Chemotherapy in Recruit Inflammatory Cells into Tumor Microenvironment of Lung Cancer Patients

  Feng, P. & Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myeloid-Derived Suppressor Cells 100%
  • Neoplasms 26%
  • Tumor Microenvironment 25%
  • Lung Neoplasms 19%
  • Drug Therapy 19%

• TMU103-AE1-B31

  Feng, P.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Study of Novel Genes Regulated by Aberrant DNA Methylation and Application in Colon Cancer Treatment

  Lin, R. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasm Genes 100%
  • Methylation 83%
  • Taiwan 82%
  • DNA Methylation 81%
  • Colonic Neoplasms 66%

• Age-Related Hearing Loss (Presbycusis)---Cisd2 Deficiency Accelerate the Hearing Defect during Aging Process-Renew

  Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Presbycusis 100%
  • Hearing 57%
  • Longevity 37%
  • Inner Ear 22%
  • Cochlea 22%

• Dementia Care and Quality Improvement

  Chien, L., Chiou, H., Chi, N. & Hu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • dementia 100%
  • health insurance 28%
  • Medical records 19%
  • utilization 17%
  • resources 9%

• The Association of Nonage Chronic Arsenic Exposure, Methylation Levels of Arsenic Metabolism Genes, and the Risk of Cancer Development

  Chiou, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • arsenic 100%
  • adulthood 37%
  • neoplasms 27%
  • methylation 24%
  • metabolism 15%

• To See Is to Believe- Visualization of the Spectrum on Chronic Kidney Disease (II)

  Jian, W., Li, Y. & Wu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health care 100%
  • Data visualization 75%
  • Patient treatment 50%
  • Disease control 49%
  • Health insurance 49%

• Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation---The Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example

  Ho, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Gene Expression 46%
  • Tumor Microenvironment 40%
  • Hyaluronan Synthases 30%
  • Fibroblasts 29%

• An Association Study of Early Arsenic Exposure and Genes Related to Arsenic Metabolic Capacity on the Risk of Cardiovascular Disease (II)

  Hsieh, F. & Chiou, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Amyloid-Beta in the Late-Onset Post-Stroke Vascular Cognitive Impairment (I)

  Hu, C., Wu, C., Chiou, H. & Chi, N.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cognitive Dysfunction 100%
  • Blood Vessels 79%
  • Amyloid 57%
  • Stroke 46%
  • Dementia 45%

• The Role of Inflammatory Gene Polymorphisms on Risk of Post-Stroke Vascular Dementia (I)

  Chiou, H., Chi, N., Lin, H., Wu, C., Hsieh, F., Hu, C. & Hsieh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 93%
  • Cognitive Dysfunction 89%
  • Blood Vessels 52%
  • Inflammation 36%
  • Whole Exome Sequencing 16%

• Disease Trajectories and Its Association with Metabolic Dysfunction of Prostate Cancer Men Following Androgen Deprivation Therapy and the Potential of Pharmacological Medication in Preventing Metastatic Diseases.

  Shao, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology