TMU Research Center of Cancer Translational Medicine

Projects

Projects per year 2010 2014 2015 2016 2017 2018 2022

• 5 Active
• 531 Finished

Projects per year

Search results

• Dementia Care and Quality Improvement

  Chien, L.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • dementia 100%
  • health insurance 28%
  • Medical records 19%
  • utilization 17%
  • resources 9%

• Application of Regioselective Substitution on 1,4-Benzoquinone Derivatives to Provide Potent Anticancer Agents

  Liou, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1,4-benzoquinone 100%
  • Wittig Olefination 54%
  • Intramolecular Cyclization 40%
  • Nucleophilic Substitution 38%
  • Regioselectivity 35%

• Determined the Role and the Mechanims of GRP94 in Mediating the Progression and Therapeutic Responses of HCC

  Huang, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • glucose-regulated proteins 100%
  • Heat-Shock Proteins 15%
  • Neoplasms 11%
  • Neoplasm Metastasis 8%
  • Preclinical Drug Evaluations 8%

• Bone-Marrow-Derived Mesenchymal Stem Cells in Prostate Cancer-Induced Bone Remodeling

  Hsieh, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipogenic 100%
  • Osteogenic 37%

• Translational Investigation for Tea Attenuate Smoking-Induced Disease---Breast Cancer and Atherosclerosis as a Mechanistic Study

  Ho, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tea 100%
  • Nicotine 26%
  • Capsules 23%
  • Breast Neoplasms 23%
  • Smoking 19%

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-6 100%
  • Hepatocellular Carcinoma 94%
  • Hypoxia 55%
  • Drug Resistance 32%
  • Neoplasms 30%

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• The Imapct of Oxidative Stress on the Pathogenesis of COPD---An Ivestigation into Its Relationship with Abnormal Inflammation, Dna Instability, Epigenetics and Cell Metabolism

  Lee, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Oxidative Stress 47%
  • Inflammation 33%
  • Blood Cells 26%
  • Glucocorticoids 21%

• Studies on the Role of ORMDL3 in Thrombin-Induced IL-8/CXCL8 Expression and Airway Inflammation

  Chen, B.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orosomucoid 100%
  • Thrombin 74%
  • Interleukin-8 34%
  • Transcription Factor AP-1 26%
  • Asthma 23%

• Evaluate the Radio-Biological Roles of miR-17-5P in Oral Cancer Cell Line OC3

  Wu, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mouth Neoplasms 100%
  • Proteins 87%
  • MicroRNAs 61%
  • Radio 56%
  • Areca 53%

• Investigation of the Oncogenic Role of Prohibitin in Breast Cancer Progression

  Huang, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Oncogenic 100%
  • Rocaglamide 67%
  • Subcellular Localization 48%
  • Cell Viability 35%
  • Plasma 21%

• Investigation on the Epigenetic Regulation of Autophagy

  Yang, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Autophagy 100%
  • Enhancer of Zeste Homolog 2 Protein 91%
  • GSK343 51%
  • Triple Negative Breast Neoplasms 41%
  • Epigenomics 21%

• Roles of Toll-Like Receptor-4 and Hif-1 in Propofol-Involved Protection against Traumatic Brain Injury-Induced Dysfunction of the Blood-Brain Barrier

  Chen, R.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Blood-Brain Barrier 100%
  • Propofol 73%
  • Hypoxia 36%
  • Brain Edema 25%
  • Craniocerebral Trauma 22%

• 抗氧化防禦基因標籤單核?酸多形性、氧化壓力生物標記與冠狀動脈心臟病之相關性(2/2)

  Yeh, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pre-Clinical and Clinical Study for Multi-Nation Intelligent Medication Safety System

  Li, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Decision support systems 100%
  • Security systems 98%
  • Health 71%
  • Automatic identification 58%
  • Health care 49%

• Role of miR-21 in Regulating TET I-Hydroxymethylcytosine and Chemotherapeutic Response in Colorectal Cancer (I)

  Yang, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • 5-hydroxymethylcytosine 84%
  • APC Genes 58%
  • DNA Methylation 55%
  • Adenomatous Polyposis Coli 51%

• 北區高階生醫產業聚落及產業規劃-台灣遠距健康產業聚落發展先導計畫

  Yen, Y. & Chen, R.

  9/1/14 → 8/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• TGF-beta誘導人類大腸癌細胞CTGF表現之機轉研究

  Chen, B.

  6/1/14 → 8/31/15

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• A Phase I, First-In-Human, Dose-Seeking Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Orally Administered MPT0E028 in Subjects with Advanced Solid Malignancies without Standard Treatment (I)

  Liou, J.

  9/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 100%
  • Histones 39%
  • Vorinostat 30%
  • Erlotinib Hydrochloride 27%
  • Sorafenib 26%

• Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases---Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (I)

  Huang, Y.

  10/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Testicular Germ Cell Tumor 100%
  • Embryonic Stem Cells 77%
  • Epigenomics 75%
  • Seminoma 73%
  • Germ Cells 71%

• 經表皮塗抹硝酸甘油軟膏於痔瘡切除術後之止痛作用

  Tam, K.

  3/1/14 → 10/31/15

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• Identification of Rewired APC Mutation Signaling Network in Chemotherapy Resistant Response in Colorectal Cancer (I)

  Huang, T.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adenomatous Polyposis Coli 100%
  • Colorectal Neoplasms 44%
  • Mutation 34%
  • Drug Resistance 28%
  • Fluorouracil 17%

• Evaluation on prevention for metabolic syndrome and diabetes mellitus through lifestyle modification intervention in pre-diabetic subjects (100-104)

  Chiou, H., Bai, C., Tang, C., Yang, S., Su, C., Liou, T., Wang, S., Chen, J., Hsieh, A. & Huang, C.

  12/24/14 → 12/5/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Metabolic Syndrome 100%
  • Life Style 88%
  • Diabetes Mellitus 86%

• 雲林縣整合性社區健康篩檢工作成果評價分析計畫案

  Chen, L.

  6/18/15 → 12/10/15

  Project: A - Government Institution › f - Other (Funded by Government)

• 104年度「健康資料加值應用雲端化服務計畫」

  Chiou, H., Hsu, C. & Chien, L.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 輻射誘導doxorubicin 釋放之研究:探討不同胺基酸分子設計之藥物載體(奈米藥物傳導Doxorubicin、Statin and Metformin 肝腫瘤超音波分子影像模型整合性研究)

  Wu, S.

  1/1/15 → 12/31/15

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• In vitro, ex vivo and clinical characterization of novel Salmonella virulence genes

  Fang, S. & Huang, M.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • Salmonella 100%
  • Virulence 62%
  • Salmonella typhimurium 54%
  • Genes 47%
  • Defensins 33%

• 建構領航國際之活躍老化監測暨決策支援系統-活躍老化資料倉儲與決策支援系統(104-107年)之需求規劃暨監造管理計畫

  Liu, C., Yeh, Y., Chiou, H. & Chi, M.

  4/30/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Application and Mechanism of Novel Fluoro-Rutaecarpine on Inhibition of Inflammation Induced Endomt

  Lin, C.

  8/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibrosis 19%
  • Inflammation 15%
  • Sumoylation 5%

• Social Medicine Discipline Research Planning and Promotion Project

  Chiou, H.

  1/1/15 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Social Medicine 100%
  • Congresses 85%
  • Fees and Charges 53%
  • Geriatric Nursing 35%
  • Research Design 34%

• A cohort study of chronic kidney disease (the 101th-104th year of the Republic Era)

  Lin, Y., Chiou, H., Hsu, Y., Wu, M., Hsieh, F., Bai, C., Hsieh, Y., Chien, L., Wang, Y., Wu, M., Yang, S., Lin, Y. & Lin, C.

  3/31/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Chronic Renal Insufficiency 100%
  • Taiwan 77%
  • Chronic Kidney Failure 68%
  • Annual Reports 21%
  • Data Systems 19%

• Preclinical evaluation of novel selective HDAC6 inhibitors for human cancers treatment

  Pan, S.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • ricolinostat 100%
  • Neoplasms 97%
  • Heterografts 90%
  • Investigational New Drug Application 86%
  • Pharmaceutical Preparations 62%

• Promoting and Establishing Technology Exchange of Evidence-Based Medicine and Knowledge Sharing of Electronic Database in Taiwan

  Chen, C., Tam, K., Chen, K., Hou, W. & Bai, C.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Evidence-Based Practice 100%
  • Evidence-Based Medicine 46%
  • Health 31%
  • Education 20%
  • Systematic Reviews 18%

• The role of miR-203 and miR-34a in EGFR activation prostate cancer metastasis

  Liu, Y.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • ErbB Receptors 100%
  • Prostatic Neoplasms 30%
  • Neoplasm Metastasis 23%
  • Prostate 15%
  • Down-Regulation 13%

• 104年度第二期癌症研究計畫-臺北醫學大學癌症研究中心計畫

  Yen, Y.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 急診室服務能力之人員配置評估模式建立

  Yeh, C.

  1/1/15 → 12/31/15

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• TMU102-AE1-B25

  Chuang, J.

  1/1/14 → 12/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 鱘龍魚軟骨萃取物於延緩老化之臨床前研究與產品開發

  Deng, W.

  1/1/15 → 12/31/15

  Project: A - Government Institution › e - Council of Agriculture

• 臺北醫學大學附設醫院之疾病個案收集與建立臺灣人體生物資料庫

  Yen, Y.

  1/1/15 → 12/31/15

  Project: A - Government Institution › f - Other (Funded by Government)

• Long-term follow-up study of health behaviors among adolescent cohort. (104年)

  Chiou, H., Chen, P., Chen, Y., Yang, S. & Chen, Y. C.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Epigenetic Characterization of Ovarian Cancer Initiating Cells

  Lai, H. & Huang, R.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • Ovarian Neoplasms 100%
  • Neoplastic Stem Cells 64%
  • Epigenomics 43%
  • 5-hydroxymethylcytosine 16%
  • Stem Cell Research 14%

• Computational analysis of gene expression profiles and genetic polymorphisms to predict the risk of osteoporosis

  Chang, W.

  1/1/15 → 12/31/15

  Project: C - Project of Alliance › j - National Taipei University of Technology

• TMU103-AE1-B12

  Lee, K.

  1/1/15 → 12/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 臺北醫學大學自有貴重儀器共用服務計畫

  Lin, C.

  11/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Syntheses of Selective Histone Deacetylase 6 inhibitors

  Liou, J.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Histone 100%
  • Tubastatin A 97%
  • Antiproliferative 46%
  • Enzyme Activity 38%
  • Bioactivity 33%

• TMU103-AE1-B06

  Lai, H.

  11/1/14 → 12/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 104年度「委託科技研究計畫--以資通訊科技提升照護品質」分項計畫5：長期照護服務導入資通訊科技之策略規劃

  Yen, Y., Chiou, H., Liu, C. & Lin, P.

  6/12/15 → 2/11/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Long-term Care 100%
  • Taiwan 24%
  • System Development 22%
  • Needs Assessment 18%
  • Managers 16%

• 第一型內皮細胞分子在C 型血管內皮生長因子調控肺腫瘤侵襲與轉移過程中扮演之角色探討

  Chien, M.

  3/1/14 → 2/29/16

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 病毒性肝炎高盛行地區非酒精性脂肪肝疾病的盛行率與發生率風險因子

  Chen, L.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 探討propofol減緩敗血症傷害的機轉: 轉譯醫學研究

  Chen, R.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital