TMU Neuroscience Research Center - Platelet Neurotrophins for Neurorestorative Biotherapy

Research Output 2004 2019

2017

Strategies to Preclude Hepatitis C Virus Entry

Burnouf, T. P. R., Liu, C. H. & Lin, L-T., Mar 8 2017, Advances in Treatment of Hepatitis C and B. InTech

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
Virus Internalization
Hepacivirus
Antiviral Agents
Satellite Viruses
End Stage Liver Disease
9 Citations (Scopus)

Tailor-made purified human platelet lysate concentrated in neurotrophins for treatment of Parkinson's disease

Chou, M. L., Wu, J. W., Gouel, F., Jonneaux, A., Tillerman, K., Renn, T. Y., Laloux, C., Chang, H. M., Lin, L. T., Devedjian, J. C., Devos, D. & Burnouf, T., Oct 1 2017, In : Biomaterials. 142, p. 77-89 13 p.

Research output: Contribution to journalArticle

Nerve Growth Factors
Platelets
Parkinson Disease
Blood Platelets
Therapeutics
2 Citations (Scopus)

The Current Global Status and Production Trends of Plasma Fractionation

Kim, M-J. & Burnouf, T. P. R., 2017, In : Korean J Blood Transfus. p. 113-125

Research output: Contribution to journalReview article

Gross Domestic Product
Plasmapheresis
Intravenous Immunoglobulins
Contracts
Developed Countries
5 Citations (Scopus)

The microbiome and transfusion in cancer patients

Goubran, H., Seghatchian, J., Radosevic, J., Ragab, G. & Burnouf, T., Jun 1 2017, In : Transfusion and Apheresis Science. 56, 3, p. 330-335 6 p.

Research output: Contribution to journalReview article

Microbiota
Neoplasms
Mucositis
Micronutrients
Vulnerable Populations
6 Citations (Scopus)

The protective effect of human platelet lysate in models of neurodegenerative disease: Involvement of the Akt and MEK pathways

Gouel, F., Do Van, B., Chou, M. L., Jonneaux, A., Moreau, C., Bordet, R., Burnouf, T. P. R., Devedjian, J. C. & Devos, D., 2017, In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

Neurodegenerative diseases
Mitogen-Activated Protein Kinase Kinases
Platelets
Neurodegenerative Diseases
Blood Platelets
25 Citations (Scopus)

Towards pathogen inactivation of red blood cells and whole blood targeting viral DNA/RNA: Design, technologies, and future prospects for developing countries

Drew, V. J., Barro, L., Seghatchian, J. & Burnouf, T., 2017, In : Blood Transfusion. 15, 6, p. 512-521 10 p.

Research output: Contribution to journalReview article

Viral DNA
Viral RNA
Developing Countries
Erythrocytes
Technology
15 Citations (Scopus)

Transfusion-related immunomodulation and cancer

Goubran, H., Sheridan, D., Radosevic, J., Burnouf, T. & Seghatchian, J., Jun 1 2017, In : Transfusion and Apheresis Science. 56, 3, p. 336-340 5 p.

Research output: Contribution to journalReview article

Immunomodulation
Neoplasms
Hemoglobins
Tissue Donors
Metabolomics
2016
10 Citations (Scopus)

Activity-based and fraction-guided analysis of Phyllanthus urinaria identifies loliolide as a potent inhibitor of hepatitis C virus entry

Chung, C. Y., Liu, C. H., Burnouf, T., Wang, G. H., Chang, S. P., Jassey, A., Tai, C. J., Tai, C. J., Huang, C. J., Richardson, C. D., Yen, M. H., Lin, C. C. & Lin, L. T., Jun 1 2016, In : Antiviral Research. 130, p. 58-68 11 p.

Research output: Contribution to journalArticle

Phyllanthus
Virus Internalization
Hepacivirus
Antiviral Agents
Hepatitis C
2 Citations (Scopus)

Anti-human platelet antigen-1α immunoglobulin G preparation intended to prevent fetal and neonatal alloimmune thrombocytopenia

Weng, Y. J., Husebekk, A., Skogen, B., Kjaer, M., Lin, L. T. & Burnouf, T., Sep 1 2016, In : PLoS One. 11, 9, e0162973.

Research output: Contribution to journalArticle

Human Platelet Antigens
Neonatal Alloimmune Thrombocytopenia
thrombocytopenia
immunoglobulin G
Immunoglobulin G
2 Citations (Scopus)
Ophthalmic Solutions
Cytokines
Safety
Serum
1 Citation (Scopus)

Convalescent Ebola plasma: Assessing neutralizing antibodies at the right stage

Burnouf, T., Dye, J. M., Ambe, J. & Abayomi, A., 2016, In : Vox Sanguinis.

Research output: Contribution to journalLetter

Neutralizing Antibodies
1 Citation (Scopus)

Convalescent Plasma for Ebola Virus Disease

GET Consortium, Jun 23 2016, In : New England Journal of Medicine. 374, 25, p. 2499 1 p.

Research output: Contribution to journalLetter

Ebola Hemorrhagic Fever
Blood Component Transfusion
Pregnancy
Cell Engineering
Tissue Engineering
Cell- and Tissue-Based Therapy
Blood Platelets
Safety

Current status and new developments in the production of plasma derivatives

Burnouf, T. P. R., Jun 28 2016, In : Vox Sanguinis. 11, p. 18-25

Research output: Contribution to journalReview article

Technology
Blood Proteins
Ethanol
Virus Integration
Protein Deficiency
120 Citations (Scopus)

Human platelet lysate: Replacing fetal bovine serum as a gold standard for human cell propagation?

Burnouf, T., Strunk, D., Koh, M. B. C. & Schallmoser, K., 2016, In : Biomaterials. 76, p. 371-387 17 p.

Research output: Contribution to journalReview article

Platelets
Blood Platelets
Cells
Serum
Cell culture

Impact of Transfusion on Cancer Growth and Outcome

Goubran, H. A., Elemary, M., Radosevich, M., Seghatchian, J., El-Ekiaby, M. & Burnouf, T., 2016, In : Cancer growth and metastasis. 9, p. 1-8 8 p.

Research output: Contribution to journalReview article

Blood Component Transfusion
Growth
Neoplasms
Precision Medicine
Blood Cell Count

Multifunctional nanoparticles for oral protein drug delivery

Chuang, E-Y., Lin, K. J., Su, F. Y., Mi, F-L., Chen, C. T., Juang, J. H. & Sung, H. W., 2016, In : Nanomedicine: Nanotechnology, Biology, and Medicine.

Research output: Contribution to journalArticle

Egtazic Acid
Drug delivery
Nanoparticles
Proteins
Glutamic Acid
13 Citations (Scopus)

One-pot green hydrothermal synthesis of fluorescent nitrogen-doped carbon nanodots for in vivo bioimaging

Kuo, T. R., Sung, S. Y., Hsu, C. W., Chang, C. J., Chiu, T. C. & Hu, C. C., Jan 1 2016, In : Analytical and Bioanalytical Chemistry. 408, 1, p. 77-82 6 p.

Research output: Contribution to journalArticle

Hydrothermal synthesis
Nitrogen
Carbon
Fluorescence
Optical Imaging

Plasma for fractionation: looking at its safety from a comprehensive angle

Burnouf, T., Nov 1 2016, In : Transfusion. 56, 11, p. 2900-2901 2 p.

Research output: Contribution to journalLetter

Safety
6 Citations (Scopus)
Dry Eye Syndromes
Ophthalmic Solutions
Safety
Serum
Research
4 Citations (Scopus)

Removal process of prion and parvovirus from human platelet lysates used as clinical-grade supplement for ex vivo cell expansion

Kao, Y. C., Bailey, A., Samminger, B., Tanimoto, J. & Burnouf, T., Jul 1 2016, In : Cytotherapy. 18, 7, p. 911-924 14 p.

Research output: Contribution to journalArticle

Parvovirus
Prions
Blood Platelets
Porcine Parvovirus
Clinical Protocols
1 Citation (Scopus)

Risks of inhibitors from recombinant factor VIII: a quarter of a century to reach the conclusion

Burnouf, T. & Strengers, P. F. W., Oct 1 2016, In : Journal of Thrombosis and Haemostasis. 14, 10, p. 2073-2074 2 p.

Research output: Contribution to journalLetter

Factor VIII
6 Citations (Scopus)

Single-use technology for solvent/detergent virus inactivation of industrial plasma products

Hsieh, Y. T., Mullin, L., Greenhalgh, P., Cunningham, M., Goodrich, E., Shea, J., Youssef, E. & Burnouf, T., Jun 1 2016, In : Transfusion. 56, 6, p. 1384-1393 10 p.

Research output: Contribution to journalArticle

Virus Inactivation
Detergents
Technology
Bovine Viral Diarrhea Viruses
Murine Leukemia Viruses
14 Citations (Scopus)

Smart blood cell and microvesicle-based Trojan horse drug delivery: Merging expertise in blood transfusion and biomedical engineering in the field of nanomedicine

Wu, Y. W., Goubran, H., Seghatchian, J. & Burnouf, T., Apr 1 2016, In : Transfusion and Apheresis Science. 54, 2, p. 309-318 10 p.

Research output: Contribution to journalReview article

Nanomedicine
Biomedical Engineering
Blood Transfusion
Blood Cells
Pharmaceutical Preparations
8 Citations (Scopus)

Solvent/detergent virally inactivated serum eye drops restore healthy ocular epithelium in a rabbit model of dry-eye syndrome

Tseng, C. L., Chen, Z. Y., Renn, T. Y., Hsiao, S. H. & Burnouf, T., Apr 1 2016, In : PLoS One. 11, 4, e0153573.

Research output: Contribution to journalArticle

Dry Eye Syndromes
Ophthalmic Solutions
blood serum
detergents
Detergents

To the editor

Burnouf, T., Conton, B. & Dye, J. M., Jun 23 2016, In : New England Journal of Medicine. 374, 25, p. 2499 1 p.

Research output: Contribution to journalLetter

2015
9 Citations (Scopus)

A Call for Incorporating Social Research in the Global Struggle against Snakebite

Gutiérrez, J. M., Burnouf, T., Harrison, R. A., Calvete, J. J., Brown, N., Jensen, S. D., Warrell, D. A. & Williams, D. J., Sep 17 2015, In : PLoS Neglected Tropical Diseases. 9, 9, e0003960.

Research output: Contribution to journalReview article

Snake Bites
Research
9 Citations (Scopus)
Dry Eye Syndromes
Blood Platelets
Animal Models
Ophthalmic Solutions
Serum
56 Citations (Scopus)

An overview of the role of microparticles/microvesicles in blood components: Are they clinically beneficial or harmful?

Burnouf, T., Chou, M. L., Goubran, H., Cognasse, F., Garraud, O. & Seghatchian, J., Oct 1 2015, In : Transfusion and Apheresis Science. 53, 2, p. 137-145 9 p.

Research output: Contribution to journalReview article

Blood Safety
Transfusion Medicine
Leukocytes
Coagulants
Blood Component Removal
14 Citations (Scopus)

Anti-inflammatory effects of platelet biomaterials in a macrophage cellular model

Renn, T. Y., Kao, Y. H., Wang, C. C. & Burnouf, T., Aug 1 2015, In : Vox Sanguinis. 109, 2, p. 138-147 10 p.

Research output: Contribution to journalArticle

Biocompatible Materials
Anti-Inflammatory Agents
Blood Platelets
Macrophages
Detergents
1 Citation (Scopus)

Blood cell-derived microparticles and nanoparticles: Multifaceted topics for research

Burnouf, T., Oct 1 2015, In : Transfusion and Apheresis Science. 53, 2, p. 106-107 2 p.

Research output: Contribution to journalEditorial

Cell-Derived Microparticles
Nanoparticles
Biomedical Research
Blood Cells
Research
6 Citations (Scopus)
Cell-Derived Microparticles
Blood Component Transfusion
Blood Cells
Differential Diagnosis
Therapeutics
32 Citations (Scopus)

Fluorescence-guided probes of aptamer-targeted gold nanoparticles with computed tomography imaging accesses for in vivo tumor resection

Li, C. H., Kuo, T. R., Su, H. J., Lai, W. Y., Yang, P. C., Chen, J. S., Wang, D. Y., Wu, Y. C. & Chen, C. C., Oct 28 2015, In : Scientific Reports. 5, 15675.

Research output: Contribution to journalArticle

Gold
Nanoparticles
Fluorescence
Tomography
Neoplasms
8 Citations (Scopus)

Human plasma-derived immunoglobulin G fractionated by an aqueous two-phase system, caprylic acid precipitation, and membrane chromatography has a high purity level and is free of detectable in vitro thrombogenic activity

Vargas, M., Segura, A., Wu, Y. W., Herrera, M., Chou, M. L., Villalta, M., León, G. & Burnouf, T., Feb 1 2015, In : Vox Sanguinis. 108, 2, p. 169-177 9 p.

Research output: Contribution to journalArticle

Chromatography
Thrombin
Immunoglobulin G
Membranes
isoleucyl-prolyl-arginine-4-nitroanilide
10 Citations (Scopus)

Minipool Caprylic Acid Fractionation of Plasma Using Disposable Equipment: A Practical Method to Enhance Immunoglobulin Supply in Developing Countries

El-Ekiaby, M., Vargas, M., Sayed, M., Gorgy, G., Goubran, H., Radosevic, M. & Burnouf, T., 2015, In : PLoS Neglected Tropical Diseases. 9, 2, e0003501.

Research output: Contribution to journalArticle

Disposable Equipment
Developing Countries
Immunoglobulins
Immunoglobulin G
Ebolavirus
19 Citations (Scopus)

Nanofiltration to remove microparticles and decrease the thrombogenicity of plasma: In vitro feasibility assessment

Chou, M. L., Lin, L. T., Devos, D. & Burnouf, T., Oct 1 2015, In : Transfusion. 55, 10, p. 2433-2444 12 p.

Research output: Contribution to journalArticle

Blood Coagulation Factors
Hemostatics
Phospholipids
Thromboplastin
Thrombin
9 Citations (Scopus)

Platelet-derived microparticles trigger THP-1 monocytic cell aggregation and release of pro-coagulant tissue factor-expressing microparticles in vitro

Lin, H. C., Chang, H. W., Hsiao, S. H., Chou, M. L., Seghatchian, J. & Burnouf, T., Oct 1 2015, In : Transfusion and Apheresis Science. 53, 2, p. 246-252 7 p.

Research output: Contribution to journalReview article

Coagulants
Cell Aggregation
Thromboplastin
Blood Platelets
Thrombin
30 Citations (Scopus)

Platelet microparticles and cancer: An intimate cross-talk

Goubran, H., Sabry, W., Kotb, R., Seghatchian, J. & Burnouf, T., Oct 1 2015, In : Transfusion and Apheresis Science. 53, 2, p. 168-172 5 p.

Research output: Contribution to journalReview article

Blood Platelets
Neoplasms
Intercellular Signaling Peptides and Proteins
Cell-Derived Microparticles
Immunologic Surveillance
67 Citations (Scopus)

Preparation, quality criteria, and properties of human blood platelet lysate supplements for ex vivo stem cell expansion

Shih, T-B. & Burnouf, T. P. R., Jan 5 2015, In : New Biotechnology. 32, 1, p. 199-211 13 p.

Research output: Contribution to journalArticle

Platelets
Stem cells
Mesenchymal Stromal Cells
Blood
Stem Cells
5 Citations (Scopus)
Prion Diseases
prion diseases
PrPSc proteins
Prions
prions
15 Citations (Scopus)

Self-assembling bubble carriers for oral protein delivery

Chuang, E-Y., Lin, K. J., Lin, P. Y., Chen, H. L., Wey, S. P., Mi, F. L., Hsiao, H. C., Chen, C. T. & Sung, H. W., Sep 1 2015, In : Biomaterials. 64, p. 115-124 10 p.

Research output: Contribution to journalArticle

Insulin
Carrier Proteins
Proteins
Acids
Gelatin
43 Citations (Scopus)

The role of microparticles in inflammation and transfusion: A concise review

Cognasse, F., Hamzeh-Cognasse, H., Laradi, S., Chou, M. L., Seghatchian, J., Burnouf, T., Boulanger, C., Garraud, O. & Amabile, N., Oct 1 2015, In : Transfusion and Apheresis Science. 53, 2, p. 159-167 9 p.

Research output: Contribution to journalReview article

Inflammation
Cytoskeletal Proteins
Membrane Glycoproteins
Lipid Bilayers
Body Fluids
9 Citations (Scopus)

Tnbp/triton X-45 treatment of plasma for transfusion efficiently inactivates hepatitis C virus

Chou, M. L., Burnouf, T., Chang, S. P., Hung, T. C., Lin, C. C., Richardson, C. D. & Lin, L. T., Feb 6 2015, In : PLoS One. 10, 2, e0117800.

Research output: Contribution to journalArticle

Hepatitis C virus
Octoxynol
Viruses
Hepacivirus
Plasmas
2014
25 Citations (Scopus)

A multicomponent strategy to improve the availability of antivenom for treating snakebite envenoming

Gutiérrez, J. M., Burnouf, T., Harrison, R. A., Calvete, J. J., Kuch, U., Warrell, D. A. & Williams, D. J., 2014, In : Bulletin of the World Health Organization. 92, 7, p. 526-532 7 p.

Research output: Contribution to journalArticle

Antivenins
Snake Bites
Developing Countries
Delivery of Health Care
Global Health

An approach to outreach patients with von Willebrand disease in Egypt by targeting women with heavy menstrual bleeding and/or bleeding symptoms

Sherif, N., Goubran, H., Hassan, A., Burnouf, T. & El-Ekiaby, M., 2014, In : Haemophilia. 20, 2, p. 238-243 6 p.

Research output: Contribution to journalArticle

von Willebrand Diseases
Egypt
Hemorrhage
von Willebrand Factor
Ferritins
12 Citations (Scopus)

Dedicated removal of immunoglobulin (Ig)A, IgM, and Factor (F)XI/activated FXI from human plasma IgG

Wu, Y. W., Champagne, J., Toueille, M., Gantier, R. & Burnouf, T., Jan 2014, In : Transfusion. 54, 1, p. 169-178 10 p.

Research output: Contribution to journalArticle

Factor XIa
Immunoglobulin A
Immunoglobulin M
Immunoglobulin G
Ceramics
21 Citations (Scopus)

Ebola: A call for blood transfusion strategy in sub-Saharan Africa

Burnouf, T., Emmanuel, J., Mbanya, D., El-Ekiaby, M., Murphy, W., Field, S. & Allain, J. P., Oct 11 2014, In : The Lancet. 384, 9951, p. 1347-1348 2 p.

Research output: Contribution to journalLetter

16 Citations (Scopus)

Ebola virus convalescent blood products: Where we are now and where we may need to go

Burnouf, T. & Seghatchian, J., 2014, In : Transfusion and Apheresis Science. 51, 2, p. 120-125 6 p.

Research output: Contribution to journalReview article

Ebolavirus
Ebola Hemorrhagic Fever
Immunoglobulins
Passive Immunization
Pandemics
12 Citations (Scopus)

Ex vivo expansion of bovine corneal endothelial cells in xeno-free medium supplemented with platelet releasate

Chou, M. L., Burnouf, T. & Wang, T. J., Jun 19 2014, In : PLoS One. 9, 6, e99145.

Research output: Contribution to journalArticle

Endothelial cells
Platelets
Corneal Endothelium
endothelial cells
endothelium
18 Citations (Scopus)

FRET-based dual-emission and pH-responsive nanocarriers for enhanced delivery of protein across intestinal epithelial cell barrier

Lu, K. Y., Lin, C. W., Hsu, C. H., Ho, Y. C., Chuang, E-T., Sung, H. W. & Mi, F. L., Oct 22 2014, In : ACS Applied Materials and Interfaces. 6, 20, p. 18275-18289 15 p.

Research output: Contribution to journalArticle

Angiogenic Proteins
Epithelial Cells
Proteins
Tight Junctions
Taurine