TMU Neuroscience Research Center - Other

Research Output 1994 2019

Filter
Article
2019
5 Citations (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50

A critical period for the development of schizophrenia-like pathology by aberrant postnatal neurogenesis

Sheu, J. R., Hsieh, C. Y., Jayakumar, T., Tseng, M. F., Lee, H. N., Huang, S. W., Manubolu, M. & Yang, C. H., Jan 1 2019, In : Frontiers in Neuroscience. 13, JUN, 635.

Research output: Contribution to journalArticle

Open Access
Neurogenesis
Schizophrenia
Pathology
Critical Period (Psychology)
Hallucinations
Hip Fractures
Poliomyelitis
Cohort Studies
Population
International Classification of Diseases
Open Access
Vertebral Artery
Infarction
Stroke
Control Groups
Intracranial Arteriosclerosis
1 Citation (Scopus)

Bimanual coordination deficits in hands following stroke and their relationship with motor and functional performance

Lai, C. H., Sung, W. H., Chiang, S. L., Lu, L. H., Lin, C. H., Tung, Y. C. & Lin, C. H., Aug 2 2019, In : Journal of NeuroEngineering and Rehabilitation. 16, 1, 14 p., 101.

Research output: Contribution to journalArticle

Open Access
Hand Strength
Hand
Stroke
Upper Extremity
Equipment and Supplies

Cerebral Small Vessel Disease Biomarkers Detection on MRI-Sensor-Based Image and Deep Learning

Hsieh, Y-Z., Luo, Y-C., Pan, C., Su, M-C., Chen, C-J. & Hsieh, K. L-C., Jun 6 2019, In : Sensors (Basel, Switzerland). 19, 11

Research output: Contribution to journalArticle

Cerebral Small Vessel Diseases
biomarkers
Biomarkers
Magnetic resonance imaging
learning
Neuronal Plasticity
Electric Impedance
Brain
Motor Evoked Potentials
Transcranial Magnetic Stimulation
2 Citations (Scopus)
Upper Extremity
Lower Extremity
Education
Cytidine Triphosphate
Information Storage and Retrieval

Endothelin-1 Induces Mesothelial Mesenchymal Transition and Correlates with Pleural Fibrosis in Tuberculous Pleural Effusions

Wu, Z-H., Tsai, J-H., Hsieh, C-Y., Chen, W-L. & Chung, C-L., Mar 29 2019, In : Journal of Clinical Medicine. 8, 4, 426.

Research output: Contribution to journalArticle

Endothelin-1
Pleural Effusion
Fibrosis
Extracellular Matrix
Pleural Diseases

HDAC6 dysfunction contributes to impaired maturation of adult neurogenesis in vivo: vital role on functional recovery after ischemic stroke

Sheu, J-R., Hsieh, C-Y., Jayakumar, T., Lin, G-Y., Lee, H-N., Huang, S-W. & Yang, C-H., Apr 18 2019, In : Journal of Biomedical Science. 26, 1, 27.

Research output: Contribution to journalArticle

Neurogenesis
Neurons
Stroke
Recovery
Patient rehabilitation
1 Citation (Scopus)

Improved voiding function by deep brain stimulation in traumatic brain-injured animals with bladder dysfunctions

Praveen Rajneesh, C., Lai, C. H., Chen, S. C., Hsieh, T. H., Chin, H. Y. & Peng, C. W., Jan 3 2019, In : International Urology and Nephrology. 51, 1, p. 41-52

Research output: Contribution to journalArticle

Deep Brain Stimulation
Urinary Bladder
Brain
Weights and Measures
Mortality
Herpes Zoster Ophthalmicus
Macular Degeneration
Cohort Studies
Retrospective Studies

New therapeutic strategy of hinokitiol in haemorrhagic shock-induced liver injury

Lu, W-J., Lin, K-H., Tseng, M-F., Yuan, K-C., Huang, H-C., Sheu, J-R. & Chen, R-J., Mar 1 2019, In : Journal of Cellular and Molecular Medicine. 23, 3, p. 1723-1734 12 p.

Research output: Contribution to journalArticle

Hemorrhagic Shock
Liver
Wounds and Injuries
Resuscitation
Therapeutics
1 Citation (Scopus)
Transcranial Magnetic Stimulation
Meta-Analysis
Lower Extremity
Randomized Controlled Trials
Stroke
1 Citation (Scopus)
Motor Cortex
Feasibility Studies
Leg
Stroke
Rehabilitation
2 Citations (Scopus)
Urinary Bladder Neoplasms
Antineoplastic Agents
G1 Phase
Ovarian Neoplasms
Solubility

The fungus-derived retinoprotectant theissenolactone C improves glaucoma-like injury mediated by MMP-9 inhibition

Lin, F. L., Cheng, Y. W., Yu, M., Ho, J. D., Kuo, Y. C., Chiou, G. C. Y., Chang, H. M., Lee, T. H. & Hsiao, G., Mar 15 2019, In : Phytomedicine. 56, p. 207-214 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 9
Glaucoma
Reperfusion Injury
Interleukin-1
Chemokine CCL2
Job Satisfaction
Administrative Personnel
Taiwan
Nursing
Informatics
2018
8 Citations (Scopus)

1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC

Ojha, R., Huang, H. L., HuangFu, W. C., Wu, Y. W., Nepali, K., Lai, M. J., Su, C. J., Sung, T. Y., Chen, Y. L., Pan, S. L. & Liou, J. P., Apr 25 2018, In : European Journal of Medicinal Chemistry. 150, p. 667-677 11 p.

Research output: Contribution to journalArticle

Hydroxamic Acids
Histone Deacetylase Inhibitors
Antineoplastic Agents
Protein Isoforms
Cells
12 Citations (Scopus)

5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes

Lee, H. Y., Fan, S. J., Huang, F. I., Chao, H. Y., Hsu, K. C., Lin, T. E., Yeh, T. K., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Jan 29 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

tau Proteins
Histone Deacetylase Inhibitors
Alzheimer Disease
Hydroxamic Acids
Phenotype
2 Citations (Scopus)

A Modular Data Glove System for Finger and Hand Motion Capture Based on Inertial Sensors

Lin, B-S., Lee, I-J., Chiang, P-Y., Huang, S-Y. & Peng, C-W., 2018, In : Journal of Medical and Biological Engineering.

Research output: Contribution to journalArticle

Fusion reactions
ROM
Sensors
Angular velocity
Patient rehabilitation

Analysis of Titin in Red and White Muscles: Crucial Role on Muscle Contractions Using a Fish Model

Wu, M. P., Chang, N. C., Chung, C. L., Chiu, W. C., Hsu, C. C., Chen, H. M., Sheu, J. R., Jayakumar, T., Chou, D. S. & Fong, T. H., Nov 18 2018, In : BioMed Research International. 2018, p. 5816875 11 p., 5816875.

Research output: Contribution to journalArticle

Connectin
Muscle Contraction
Fish
Muscle
Muscles

An Antithrombotic Strategy by Targeting Phospholipase D in Human Platelets

Lu, W. J., Chung, C. L., Chen, R. J., Huang, L. T., Lien, L. M., Chang, C. C., Lin, K. H. & Sheu, J. R., Nov 14 2018, In : Journal of Clinical Medicine. 7, 11

Research output: Contribution to journalArticle

Phospholipase D
Blood Platelets
Platelet Activation
Platelet Aggregation
Thrombosis
2 Citations (Scopus)

A novel hydroxamate-based compound WMJ-J-09 causes head and neck squamous cell carcinoma cell death via LKB1-AMPK-p38MAPK-p63-survivin cascade

Yen, C. S., Choy, C. S., Huang, W. J., Huang, S. W., Lai, P. Y., Yu, M. C., Shiue, C., Hsu, Y. F. & Hsu, M. J., Mar 1 2018, In : Frontiers in Pharmacology. 9, MAR, p. 1-17 17 p., 167.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Cell Death
Microtubules
Liver
Phosphorylation

A novel missense mutation of the GTP cyclohydrolase 1 gene in a Taiwanese family with dopa-responsive dystonia: A case report

Yang, C. C., Wang, W. C., Yeh, T. H., Chen, T. H., Liu, Y. L., Lu, M. K., Lu, C. S. & Tsai, C. H., Feb 1 2018, In : Clinical Neurology and Neurosurgery. 165, p. 21-23 3 p.

Research output: Contribution to journalArticle

GTP Cyclohydrolase
Missense Mutation
Dystonia
Genes
Leg
1 Citation (Scopus)

Atypical anxiety-related amygdala reactivity and functional connectivity in Sant Mat meditation

Chen, C., Chen, Y. C., Chen, K. L. & Cheng, Y., Dec 4 2018, In : Frontiers in Behavioral Neuroscience. 12, 298.

Research output: Contribution to journalArticle

Meditation
Amygdala
Anxiety
Happiness
Fear

Biofuel and biochemical analysis of amphora coffeaeformis RR03, a novel marine diatom, cultivated in an open raceway pond

Rajaram, M. G., Nagaraj, S., Manjunath, M., Boopathy, A. B., Kurinjimalar, C., Rengasamy, R., Jayakumar, T., Sheu, J. R. & Li, J. Y., Jun 1 2018, In : Energies. 11, 6, en11061341.

Research output: Contribution to journalArticle

Diatoms
Ponds
Biofuels
Biomass
Fatty Acids
4 Citations (Scopus)

C9orf72 is essential for neurodevelopment and motility mediated by Cyclin G1

Yeh, T. H., Liu, H. F., Li, Y. W., Lu, C. S., Shih, H. Y., Chiu, C. C., Lin, S. J., Huang, Y. C. & Cheng, Y. C., Jun 1 2018, In : Experimental Neurology. 304, p. 114-124 11 p.

Research output: Contribution to journalArticle

Cyclin G1
Embryonic Structures
GTP Phosphohydrolases
Zebrafish
Apoptosis
5 Citations (Scopus)

Ceramide synthase 6 predicts the prognosis of human gastric cancer: It functions as an oncoprotein by dysregulating the SOCS2/JAK2/STAT3 pathway

Uen, Y. H., Fang, C. L., Lin, C. C., Hseu, Y. C., Hung, S. T., Sun, D. P. & Lin, K. Y., Jan 1 2018, (Accepted/In press) In : Molecular Carcinogenesis.

Research output: Contribution to journalArticle

Oncogene Proteins
Stomach Neoplasms
Cell Proliferation
Heterografts
Carcinogenesis
4 Citations (Scopus)

Cerebral Motor Functional Connectivity at the Acute Stage: An Outcome Predictor of Ischemic Stroke

Chi, N. F., Ku, H. L., Chen, D. Y. T., Tseng, Y. C., Chen, C. J., Lin, Y. C., Hsieh, Y. C., Chan, L., Chiou, H. Y., Hsu, C. Y. & Hu, C. J., Dec 1 2018, In : Scientific Reports. 8, 1, 16803.

Research output: Contribution to journalArticle

Stroke
Motor Cortex
Multivariate Analysis
Odds Ratio
Magnetic Resonance Imaging
7 Citations (Scopus)

CME-1, a novel polysaccharide, suppresses iNOS expression in lipopolysaccharide-stimulated macrophages through ceramide-initiated protein phosphatase 2A activation

Sheu, J. R., Chen, Z. C., Hsu, M. J., Wang, S. H., Jung, K. W., Wu, W. F., Pan, S. H., Teng, R. D., Yang, C. H. & Hsieh, C. Y., Feb 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 2, p. 999-1013 15 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Ceramides
Nitric Oxide Synthase Type II
Polysaccharides
Lipopolysaccharides
2 Citations (Scopus)

Distinct methylation profile of mucinous ovarian carcinoma reveals susceptibility to proteasome inhibitors

Liew, P. L., Huang, R. L., Weng, Y. C., Fang, C. L., Hui-Ming Huang, T. & Lai, H. C., Jul 15 2018, In : International Journal of Cancer. 143, 2, p. 355-367 13 p.

Research output: Contribution to journalArticle

Mucinous Adenocarcinoma
Proteasome Inhibitors
Methylation
Gastrointestinal Neoplasms
Ovarian epithelial cancer
1 Citation (Scopus)

Effects of collagen matrix and bioreactor cultivation on cartilage regeneration of a full-thickness critical-size knee joint cartilage defects with subchondral bone damage in a rabbit model

Wang, K. H., Wan, R., Chiu, L. H., Tsai, Y. H., Fang, C. L., Bowley, J. F., Chen, K. C., Shih, H. N. & Lai, W. F. T., May 1 2018, In : PLoS One. 13, 5, e0196779.

Research output: Contribution to journalArticle

knees
Cartilage
Bioreactors
bioreactors
Knee Joint
Central Nervous System Diseases
Therapeutics
Migraine Disorders
Benign Paroxysmal Positional Vertigo
Cerebrovascular Disorders
1 Citation (Scopus)

Gamma Knife surgery for clival epidural-osseous dural arteriovenous fistulas

Lee, C. C., Chen, C. J., Chen, S. C., Yang, H. C., Lin, C. J., Wu, C. C., Chung, W. Y., Guo, W. Y., Pan, D. H. C., Shiau, C. Y. & Wu, H. M., May 1 2018, In : Journal of Neurosurgery. 128, 5, p. 1364-1371 8 p.

Research output: Contribution to journalArticle

Central Nervous System Vascular Malformations
Intracranial Hemorrhages
Therapeutics
Drainage
Angiography
6 Citations (Scopus)

Hinokitiol inhibits migration of A549 lung cancer cells via suppression of MMPs and induction of antioxidant enzymes and apoptosis

Jayakumar, T., Liu, C. H., Wu, G. Y., Lee, T. Y., Manubolu, M., Hsieh, C. Y., Yang, C. H. & Sheu, J. R., Mar 22 2018, In : International Journal of Molecular Sciences. 19, 4, 939.

Research output: Contribution to journalArticle

Enzyme Induction
antioxidants
apoptosis
Cell death
Antioxidants
4 Citations (Scopus)

Inhibitory effect of PDGF-BB and serum-stimulated responses in vascular smooth muscle cell proliferation by hinokitiol via up-regulation of p21 and p53

Li, J-Y., Liu, C-P., Shiao, W-C., Jayakumar, T., Li, Y-S., Chang, N-C., Huang, S-Y. & Hsieh, C-Y., Jan 1 2018, In : Archives of Medical Science. 14, 3, p. 579-587 9 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Smooth Muscle Myocytes
Up-Regulation
Cell Proliferation
Serum
2 Citations (Scopus)

Ir-6: A Novel Iridium (III) Organometallic Derivative for Inhibition of Human Platelet Activation

Shyu, R. S., Khamrang, T., Sheu, J. R., Hsia, C. W., Velusamy, M., Hsia, C. H., Chou, D. S. & Chang, C. C., Jan 1 2018, In : Bioinorganic Chemistry and Applications. 2018, p. 8291393 8291393.

Research output: Contribution to journalArticle

Iridium
Platelet Activation
Organometallics
Platelets
Collagen
5 Citations (Scopus)
Tennis Elbow
Elbow
Wrist
Cross-Over Studies
Pain
2 Citations (Scopus)

Licochalcone A attenuates glioma cell growth in vitro and in vivo through cell cycle arrest

Lu, W. J., Wu, G. J., Chen, R. J., Chang, C. C., Lien, L. M., Chiu, C. C., Tseng, M. F., Huang, L. T. & Lin, K. H., Aug 1 2018, In : Food and Function. 9, 8, p. 4500-4507 8 p.

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
Glioma
cell growth
licorice
neoplasms
4 Citations (Scopus)

Loss of cyclin-dependent kinase-like 2 predicts poor prognosis in gastric cancer, and its overexpression suppresses cells growth and invasion

Fang, C. L., Uen, Y. H., Chen, H. K., Hseu, Y. C., Lin, C. C., Hung, S. T., Sun, D. P. & Lin, K. Y., Jul 1 2018, In : Cancer Medicine. 7, 7, p. 2993-3002 10 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 2
Stomach Neoplasms
Growth
Disease-Free Survival
Cell Proliferation
23 Citations (Scopus)

LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study

International Parkinsonism Genetics Network, Jul 1 2018, In : The Lancet Neurology. 17, 7, p. 597-608 12 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Parkinson Disease
Genome
Dementia
Genes
1 Citation (Scopus)

Mechanism of free radical generation in platelets and primary hepatocytes: A novel electron spin resonance study

Wang, C. L., Yang, P. S., Tsao, J. T., Jayakumar, T., Wang, M. J., Sheu, J. R. & Chou, D. S., Jan 1 2018, In : Molecular Medicine Reports. 17, 1, p. 2061-2069 9 p.

Research output: Contribution to journalArticle

Electron Spin Resonance Spectroscopy
Platelets
Free Radicals
Paramagnetic resonance
Hepatocytes

Mechanisms of TQ-6, a Novel Ruthenium-Derivative Compound, against Lipopolysaccharide-Induced In Vitro Macrophage Activation and Liver Injury in Experimental Mice: The Crucial Role of p38 MAPK and NF-κB Signaling

Hsia, C-H., Velusamy, M., Jayakumar, T., Chen, Y-J., Hsia, C-W., Tsai, J-H., Teng, R-D. & Sheu, J-R., Nov 19 2018, In : Cells. 7, 11

Research output: Contribution to journalArticle

Ruthenium Compounds
Ruthenium
Macrophage Activation
Macrophages
p38 Mitogen-Activated Protein Kinases
2 Citations (Scopus)

Neovascular age-related macular degeneration is associated with cataract surgery

Ho, J. D., Xirasagar, S., Kao, L. T. & Lin, H. C., Mar 2018, In : Acta Ophthalmologica. 96, 2, p. e213-e217

Research output: Contribution to journalArticle

Macular Degeneration
Cataract
Confidence Intervals
Urbanization
Health Insurance
2 Citations (Scopus)
brain damage
Neuroprotective Agents
medicine
Medicine
mice
6 Citations (Scopus)
Knee Osteoarthritis
Meta-Analysis
Pain
Visual Analog Scale
PubMed
2 Citations (Scopus)
norcantharidin
Integrins
Fibrinogen
Blood Platelets
Clot Retraction
5 Citations (Scopus)

Novel iridium (III)-derived organometallic compound for the inhibition of human platelet activation

Shyu, K. G., Velusamy, M., Hsia, C. W., Yang, C. H., Hsia, C. H., Chou, D. S., Jayakumar, T., Sheu, J. R. & Li, J. Y., May 1 2018, In : International Journal of Molecular Medicine. 41, 5, p. 2589-2600 12 p.

Research output: Contribution to journalArticle

Organometallic Compounds
Iridium
Platelet Activation
Platelet Aggregation
Collagen