Projects per year
Organization profile
Organisation profile
宗旨：
促進本校生技醫藥商品化發展，提供一校三院同仁醫藥品研發服務，以開發具有創新性與前瞻性之生技醫藥產品開發為宗旨。
背景：
生技醫藥為我國重要產業，建立藥品及醫材開發的關鍵價值鏈平台是校園研究成果產業化最大的助力。為有效統整及加速本校之新藥及醫材研發能量，規劃成立臺北醫學大學生技醫藥商品化中心(TMU Biomedical Commercialization Center)，藉由商品化中心跨院系所專業團隊間的整合運作，提供一校三院同仁生技藥品臨床前到IND申請之臨床前研究(pre-clinical study)諮詢與服務。此外，透過北醫事業發展處協助醫藥品商品化開發策略，包含藥物市場定位分析，法規、專利檢索和諮詢服務，技術轉移或尋求業界承接產學合作案，及衍生新創事業體之相關規劃。
目的：
整合新藥開發及醫療器材從臨床前研究到IND/IDE所需之技術發展平台(Research Development)，提供校內外單位委託合作或共同開發之服務。
搭配事業發展處之資源協助擬定生技醫藥品商業化發展策略(Business Development)、專利布局及商業化輔導，以加速產出具有創新性與前瞻性的生技醫藥品。
初期以藥品的商業化平台為目標：規劃由藥物設計/合成與篩選、藥理活性、藥物動力學、藥物代謝、藥效、毒理、小試量產、製劑開發等提供平台服務。
Fingerprint Dive into the research topics where TMU Biomedical Commercialization Center is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Histone Deacetylase Inhibitors
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Cells
Chemical Compounds
Histone Deacetylases
Medicine & Life Sciences
Apoptosis
Medicine & Life Sciences
Mucocutaneous Lymph Node Syndrome
Medicine & Life Sciences
Tubulin
Medicine & Life Sciences
Inhibitory Concentration 50
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Profiles
Wei-Chiao Chang
- Department of Clinical Pharmacy
- Master Program for Clinical Pharmacogenomics and Pharmacoproteomics
- Ph.D Program in Biotechnology Research and Development
- TMU Research Center of Cancer Translational Medicine
- TMU Biomedical Commercialization Center
Person: Researcher
Projects 2010 2020
抗熱休克蛋白抑制劑：以嘧啶為骨架利用有機金屬耦合反應合成系列衍生物
8/1/19 → 7/1/20
Project: A - Government Institution › b - Ministry of Science and Technology
利用組蛋白去乙醯?抑制劑以增強免疫檢查點抑制劑效用及其機制探討
8/1/19 → 7/1/20
Project: A - Government Institution › b - Ministry of Science and Technology
探討Aroylindoline衍生物類小分子藥物應用於眼腦血管與神經相關之視網膜病變-小分子應用治療視網膜病變之合成
1/1/19 → 12/1/19
Project: A - Government Institution › d - Ministry of Education
Research Output 1996 2020
Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell migration via PKCα-mediated AHR-HDAC interactions
Tsai, C. H., Li, C. H., Liao, P. L., Chang, Y. W., Cheng, Y. W. & Kang, J. J., Feb 2020, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1867, 2, 118564.Research output: Contribution to journal › Article
Aryl Hydrocarbon Receptors
Histone Deacetylase Inhibitors
Histone Deacetylases
Stomach Neoplasms
Cell Movement
1
Citation
(Scopus)
N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression
Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., Jan 1 2020, In : European Journal of Medicinal Chemistry. 185, p. 111725 111725.Research output: Contribution to journal › Article
Anilides
HSP90 Heat-Shock Proteins
Histone Deacetylase Inhibitors
Histone Deacetylases
Down-Regulation
Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment
Kaur, N., Fang, Y. C., Lee, H. Y., Singh, A., Nepali, K., Lin, M. H., Yeh, T. K., Lai, M. J., Chan, L., Tu, Y. K., Banerjee, S., Hu, C. J. & Liou, J. P., Feb 1 2020, In : European Journal of Medicinal Chemistry. 187, 111915.Research output: Contribution to journal › Article
Azepines
Histone Deacetylase Inhibitors
Blood Vessels
Acetylation
Acrylamide