The Ph.D. Program for Translational Medicine

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1995 2020

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2 Citations (Scopus)

CRP-level-associated polymorphism rs1205 within the CRP gene is associated with 2-hour glucose level: The SAPPHIRe study

Sheu, W. H. H., Wang, W. C., Wu, K. D., He, C. T., Hwu, C. M., Quertermous, T., Hsieh, W. S., Lee, W. J., Ting, C. T., Chen, Y. D. I. & Hsiung, C. A., Dec 1 2017, In : Scientific Reports. 7, 1, p. 7987

Research output: Contribution to journalArticle

C-Reactive Protein
Insulin Resistance
Hypertension
Glucose
Genes
4 Citations (Scopus)
Taiwan
Internet
Curriculum
Medical Students
Hypermedia

Cyproheptadine use in hepatocellular carcinoma

Hsieh, M. C., Lee, W. H., Wu, A. T. H., Chow, J. M., Chang, C. L., Yuan, K. S. P. & Wu, S. Y., 2017, In : American Journal of Cancer Research. 7, 3, p. 584-602 19 p.

Research output: Contribution to journalArticle

Cyproheptadine
Hepatocellular Carcinoma
Palliative Care
Cause of Death
Therapeutics
2 Citations (Scopus)
cancer
statistical significance
system development
Disease
30 Citations (Scopus)

Decorin binds fibrinogen in a Zn2+-dependent interaction

Dugan, T. A., Yang, V. W. C., McQuillan, D. J. & Höök, M., Apr 18 2003, In : Journal of Biological Chemistry. 278, 16, p. 13655-13662 8 p.

Research output: Contribution to journalArticle

Decorin
Fibrinogen
Proteoglycans
Metalloproteins
Fluorescence Polarization
32 Citations (Scopus)

Decorin modulates fibrin assembly and structure

Dugan, T. A., Yang, V. W. C., McQuillan, D. J. & Höök, M., Dec 15 2006, In : Journal of Biological Chemistry. 281, 50, p. 38208-38216 9 p.

Research output: Contribution to journalArticle

Decorin
Fibrin
Fibrinogen
D region
Fibers
Open Access
hormones
Nerve Growth Factors
releasing
Endometriosis
Gonadotropin-Releasing Hormone
23 Citations (Scopus)

Delayed animal aging through the recovery of stem cell senescence by platelet rich plasma

Liu, H. Y., Huang, C. F., Lin, T. C., Tsai, C. Y., Tina Chen, S. Y., Liu, A., Chen, W. H., Wei, H. J., Wang, M. F., Williams, D. F. & Deng, W. P., Dec 1 2014, In : Biomaterials. 35, 37, p. 9767-9776 10 p.

Research output: Contribution to journalArticle

Platelet-Rich Plasma
Cell Aging
Platelets
Stem cells
Animals
12 Citations (Scopus)

Destabilization of KLF10, a tumor suppressor, relies on thr93 phosphorylation and isomerase association

Hwang, Y. C., Yang, C. H., Lin, C. H., Ch'ang, H. J., Chang, V. H. S. & Yu, W. C. Y., Dec 2013, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1833, 12, p. 3035-3045 11 p.

Research output: Contribution to journalArticle

Isomerases
Phosphorylation
Neoplasms
Proteins
Peptidylprolyl Isomerase
20 Citations (Scopus)

Destruxin B inhibits hepatocellular carcinoma cell growth through modulation of the Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition

Huynh, T. T., Rao, Y. K., Lee, W. H., Chen, H. A., Le, T. D. Q., Tzeng, D. T. W., Wang, L. S., Wu, A. T. H., Lin, Y. F., Tzeng, Y. M. & Yeh, C-T., Jun 2014, In : Toxicology in Vitro. 28, 4, p. 552-561 10 p.

Research output: Contribution to journalArticle

Catenins
Wnt Signaling Pathway
Epithelial-Mesenchymal Transition
Cell growth
Hepatocellular Carcinoma
1 Citation (Scopus)

Destruxin B suppresses drug-resistant colon tumorigenesis and stemness is associated with the upregulation of miR-214 and downregulation of mTOR/β-catenin pathway

Wu, S. Y., Huang, Y. J., Tzeng, Y. M., Huang, C. Y. F., Hsiao, M., Wu, A. T. H. & Huang, T. H., Oct 1 2018, In : Cancers. 10, 10, 353.

Research output: Contribution to journalArticle

Catenins
Sirolimus
Colonic Neoplasms
Colon
Carcinogenesis
8 Citations (Scopus)

Determination of cryoprotectant for magnetic cryopreservation of dental pulp tissue

Lee, S. Y. S., Sun, C. H. B., Kuo, T. F., Huang, Y. H., Jeng, J. H., Yang, J. C. & Yang, W. C. V., Jun 1 2012, In : Tissue Engineering - Part C: Methods. 18, 6, p. 397-407 11 p.

Research output: Contribution to journalArticle

Dental Pulp
Cryopreservation
Pulp
Tooth
Tissue
Health Level Seven
Medical Informatics
Electronic Health Records
Interoperability
Information technology
7 Citations (Scopus)

Developing an NLP and IR-based algorithm for analyzing gene-disease relationships

Yen, Y. T., Chen, B., Chiu, H. W., Lee, Y. C., Li, Y. C. & Hsu, C-Y., 2006, In : Methods of Information in Medicine. 45, 3, p. 321-329 9 p.

Research output: Contribution to journalArticle

Natural Language Processing
Information Storage and Retrieval
Genes
Oligonucleotide Array Sequence Analysis
Research Personnel
12 Citations (Scopus)

Developing guideline-based decision support systems using protégé and jess

Chen, C-F., Chen, K., Hsu, C-Y. & Li, Y-C., Jun 2011, In : Computer Methods and Programs in Biomedicine. 102, 3, p. 288-294 7 p.

Research output: Contribution to journalArticle

Clinical Decision Support Systems
Decision support systems
Medical Order Entry Systems
Electronic Prescribing
Guidelines
11 Citations (Scopus)
docetaxel
Lecithins
Drug Delivery Systems
Therapeutics
Neoplasms
5 Citations (Scopus)

Development and deployment of a web-based physician order entry system

Lee, Y. L., Hsu, C-Y., Hsieh, D. & Li, Y. C., 2001, In : International Journal of Medical Informatics. 62, 2-3, p. 135-142 8 p.

Research output: Contribution to journalArticle

Physicians
Databases
Taiwan
Internet
Medicine
14 Citations (Scopus)

Development and implementation of a national telehealth project for long-term care: A preliminary study

Hsu, M. H., Chu, T. B., Yen, J. C., Chiu, W. T., Yeh, G. C., Chen, T. J., Sung, Y. J., Hsiao, J. & Li, Y. C. J., Mar 2010, In : Computer Methods and Programs in Biomedicine. 97, 3, p. 286-292 7 p.

Research output: Contribution to journalArticle

Telemedicine
Long-Term Care
Home Care Services
Cross Infection
Delivery of Health Care
10 Citations (Scopus)

Development of a growth-hormone-conjugated nanodiamond complex for cancer therapy

Chu, H. L., Chen, H. W., Tseng, S. H., Hsu, M. H., Ho, L. P., Chou, F. H., Li, M. P. H. Y., Chang, Y. C., Chen, P. H., Tsai, L. Y., Chou, C. C., Chen, J. S., Cheng, T. M. & Chang, C. C., 2014, In : ChemMedChem. 9, 5, p. 1023-1029 7 p.

Research output: Contribution to journalArticle

Nanodiamonds
Growth Hormone
Cells
Lasers
Somatotropin Receptors
10 Citations (Scopus)

Differential distributions of CSE1L/CAS and E-cadherin in the polarized and non-polarized epithelial glands of neoplastic colorectal epithelium

Uen, W. C., Tai, C-J., Shen, S-C., Lee, W-R., Tsao, T. Y., Deng, W-P., Chiou, H-Y., Hsu, C-H., Hsieh, C. I., Liao, C. F. & Jiang, M. C., Oct 2010, In : Journal of Molecular Histology. 41, 4-5, p. 259-266 8 p.

Research output: Contribution to journalArticle

Cadherins
Epithelium
Epithelial Cells
Staining and Labeling
Cell Polarity
4 Citations (Scopus)

Direct binding to integrins and loss of disulfide linkage in IL-1β are involved in the agonistic action of IL-1β

Takada, Y. K., Yu, J., Fujita, M., Saegusa, J., Wu, C. Y. & Takada, Y., Jan 1 2017, In : Journal of Biological Chemistry. 292, 49, p. 20067-20075 9 p.

Research output: Contribution to journalArticle

Interleukin-1
Integrins
Disulfides
Interleukin-1 Receptors
Mutation
4 Citations (Scopus)

Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling

Prieto, D. M. C., Cheng, Y., Chang, C. C., Yu, J., Takada, Y. K. & Takada, Y., Sep 1 2017, In : PLoS One. 12, 9, e0184285.

Research output: Contribution to journalArticle

IGF Type 1 Receptor
integrins
somatomedins
Somatomedins
Integrins
2 Citations (Scopus)

Discrimination and calibration are concurrently required for model comparison

Chiu, J. S., Yu, F. C. & Li, Y. C., Sep 20 2006, In : International Journal of Cardiology. 112, 2, p. 245-246 2 p.

Research output: Contribution to journalArticle

Neural Networks (Computer)
Bayes Theorem
Statistical Models
Calibration
Myocardial Infarction
4 Citations (Scopus)

Disease universe: Visualisation of population-wide disease-wide associations

Moldovan, M., Enikeev, R., Syed-Abdul, S., Nguyen, P. A., Chang, Y-C. & Li, Y. C., 2014, In : Advances in Systems Science and Applications. 14, 2, p. 144-158 15 p.

Research output: Contribution to journalArticle

Visualization
Health
6 Citations (Scopus)

Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells

Huang, T. C., Lee, P. T., Wu, M. H., Huang, C. C., Ko, C. Y., Lee, Y. C., Lin, D. Y., Cheng, Y. W. & Lee, K. H., Aug 1 2017, In : PLoS One. 12, 8, e0181034.

Research output: Contribution to journalArticle

RNA Isoforms
colorectal neoplasms
Colorectal Neoplasms
Catenins
Cells

DNA: a native nano-wire in nature

Jangjian, P. C., Tseng, S-H., Tsai, C-M., Cheng, T-M., Chu, H-L. & Chang, C-C., 2010, In : Instruments Today. 31, p. 61-71

Research output: Contribution to journalArticle

1 Citation (Scopus)

DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation

Lai, S. C., Su, Y. T., Chi, C. C., Kuo, Y. C., Lee, K. F., Wu, Y. C., Lan, P. C., Yang, M. H., Chang, T. S. & Huang, Y. H., Nov 26 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 474.

Research output: Contribution to journalArticle

Open Access
Octamer Transcription Factors
Methyltransferases
Hepatocellular Carcinoma
Interleukin-6
DNA
5 Citations (Scopus)

Do all hypnotic and sedatives have risk for cancer?

Usman, I., Jian, W. S., Huang, C. W., Inayat, A. & Li, Y. C., 2016, In : Sleep Medicine.

Research output: Contribution to journalArticle

Hypnotics and Sedatives
Neoplasms
4 Citations (Scopus)

Does aspirin use reduce the risk for cancer?

Usman, I., Yang, H. C., Jian, W. S., Yen, Y. & Li, Y. C., Feb 1 2017, In : Journal of Investigative Medicine. 65, 2, p. 391-392 2 p.

Research output: Contribution to journalArticle

Aspirin
Digestive system
Digestive System
Neoplasms
International Classification of Diseases
4 Citations (Scopus)
Clinical Decision Support Systems
Decision support systems
Randomized Controlled Trials
Physicians
Patient Safety
24 Citations (Scopus)
Intensity-Modulated Radiotherapy
Chemoradiotherapy
Thorax
Mortality
Neoplasms
20 Citations (Scopus)

Dovitinib synergizes with oxaliplatin in suppressing cell proliferation and inducing apoptosis in colorectal cancer cells regardless of RAS-RAF mutation status

Gaur, S., Chen, L., Ann, V., Lin, W. C., Wang, Y., Chang, V. H. S., Hsu, N. Y., Shia, H. S. & Yen, Y., Feb 4 2014, In : Molecular Cancer. 13, 1, 21.

Research output: Contribution to journalArticle

oxaliplatin
Colorectal Neoplasms
Cell Proliferation
Heterografts
Colonic Neoplasms
3 Citations (Scopus)
Catenins
Neoplastic Stem Cells
Diterpenes
Liver Neoplasms
Wnt Signaling Pathway
10 Citations (Scopus)

Dual inhibition of PIK3C3 and FGFR as a new therapeutic approach to treat bladder cancer

Chen, C. H., Changou, C. A., Hsieh, T. H., Lee, Y. C., Chu, C. Y., Hsu, K. C., Wang, H. C., Lin, Y. C., Lo, Y. N., Liu, Y. R., Liou, J. P. & Yen, Y., Mar 1 2018, In : Clinical Cancer Research. 24, 5, p. 1176-1189 14 p.

Research output: Contribution to journalArticle

Autophagy
Urinary Bladder Neoplasms
Cell Death
Therapeutics
Clustered Regularly Interspaced Short Palindromic Repeats
5 Citations (Scopus)

Early application of low-level laser may reduce the incidence of postherpetic neuralgia (PHN)

Chen, Y-T., Wang, H-H., Wang, T-J., Li, Y-C. & Chen, T-J., Sep 2016, In : Journal of the American Academy of Dermatology. 75, 3, p. 572-577 6 p.

Research output: Contribution to journalArticle

Postherpetic Neuralgia
Lasers
Incidence
Odds Ratio
Confidence Intervals
24 Citations (Scopus)

Easy and low-cost identification of metabolic syndrome in patients treated with second-generation antipsychotics: Artificial neural network and logistic regression models

Lin, C. C., Bai, Y. M., Chen, J. Y., Hwang, T. J., Chen, T. T., Chiu, H. W. & Li, Y. C., Mar 2010, In : Journal of Clinical Psychiatry. 71, 3, p. 225-234 10 p.

Research output: Contribution to journalArticle

Antipsychotic Agents
Logistic Models
Costs and Cost Analysis
Area Under Curve
Blood Pressure
20 Citations (Scopus)
Esophagectomy
Chemoradiotherapy
Radiotherapy
Thorax
Confidence Intervals

Effective Sirolimus Treatment for Refractory Spindle Cell Haemangioma

Ho, C. B., Hsieh, K., Chen, W. Y., Lin, Y. T., Chiou, J. F., Lee, H. L. & Shiah, H. S., May 11 2018, In : British Journal of Dermatology.

Research output: Contribution to journalArticle

Sirolimus
Hemangioma
Blood Vessels
Enchondromatosis
Therapeutics

Effect of Calcium Sulfate on Osteopontin Expression in U-2 Osteosarcoma Cells

Chang, Y-C., Wang, D-J., Lee, S-Y., Chang, W-C. & Yang, W-C. V., 2008, In : Journal of Dental Sciences. 3, 1, p. 30-37 8 p.

Research output: Contribution to journalArticle

Calcium Sulfate
Osteopontin
Osteosarcoma
Osteoblasts
Osteogenesis
1 Citation (Scopus)

Effect of implementation of a coded problem list entry subsystem

Chen, C. C., Chang, C. H., Peng, Y. C., Poon, S. K., Huang, S. C. & Li, Y. C. J., Oct 1 2016, In : Computer Methods and Programs in Biomedicine. 134, p. 1-9 9 p.

Research output: Contribution to journalArticle

Electronic Health Records
Quality of Health Care
Motivation
Physicians
Electronic medical equipment

Effect of Preoperative Dutasteride on Holmium Laser Enucleation of the Prostate

Shigemura, K., Kitagawa, K., Chen, K. C., Sung, S. Y. & Fujisawa, M., Jan 1 2019, (Accepted/In press) In : Urologia Internationalis.

Research output: Contribution to journalArticle

Solid-State Lasers
Prostate
Prostate-Specific Antigen
Oxidoreductases
Urinary Incontinence
6 Citations (Scopus)

Effects of a medical expert system on differential diagnosis of renal masses: A prospective study

Chang, P. L., Li, Y. C., Huang, S. T., Wang, T. M. & Hsieh, M. L., Jan 1996, In : Computerized Medical Imaging and Graphics. 20, 1, p. 43-48 6 p.

Research output: Contribution to journalArticle

Expert Systems
Expert systems
Differential Diagnosis
Prospective Studies
Kidney
27 Citations (Scopus)

Effects of and satisfaction with short message service reminders for patient medication adherence: A randomized controlled study

Huang, H. L., Li, Y. C. J., Chou, Y. C., Hsieh, Y. W., Kuo, F., Tsai, W. C., Chai, S. D., Lin, B. Y. J., Kung, P. T. & Chuang, C. J., Nov 16 2013, In : BMC Medical Informatics and Decision Making. 13, 1, 127.

Research output: Contribution to journalArticle

Text Messaging
Medication Adherence
Patient Compliance
Control Groups
Appointments and Schedules
3 Citations (Scopus)
Peritoneal Dialysis
renal function
dialysis
Cholesterol
cholesterol
Epidermal Growth Factor Receptor
Squamous Cell Carcinoma
Lung Neoplasms
Adenocarcinoma
Radiotherapy
62 Citations (Scopus)

Efficacy of rituximab for pemphigus: A systematic review and meta-analysis of different regimens

Wang, H. H., Liu, C. W., Li, Y. C. & Huang, Y-C., Nov 1 2015, In : Acta Dermato-Venereologica. 95, 8, p. 928-932 5 p.

Research output: Contribution to journalArticle

Pemphigus
Meta-Analysis
Rituximab
Recurrence
Lymphoma
6 Citations (Scopus)
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Radiotherapy
Thorax
Therapeutics
1 Citation (Scopus)

EGFR, SMAD7, and TGFBR2 polymorphisms are associated with colorectal cancer in patients with lynch syndrome

Kamiza, A. B., Wang, W. C., You, J. F., Tang, R., Wang, Y. T., Chien, H. T., Lai, C. H., Chiu, L. L., Lo, T. P., Hung, K. Y., Hsiung, C. A. & Yeh, C. C., Oct 1 2018, In : Anticancer Research. 38, 10, p. 5983-5990 8 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Epidermal Growth Factor Receptor
Colorectal Neoplasms
Genotype
Transforming Growth Factors
6 Citations (Scopus)

Electronic health record goes personal world-wide.

Li, Y. C., Lee, P. S., Jian, W. S. & Kuo, C. H., 2009, In : Yearbook of medical informatics. p. 40-43 4 p.

Research output: Contribution to journalArticle

Electronic Health Records
Privacy
Information Dissemination
Research Personnel
Delivery of Health Care