The Ph.D. Program for Translational Medicine

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Article
2020
1 Citation (Scopus)

Application of a Common Data Model (CDM) to rank the paediatric user and prescription prevalence of 15 different drug classes in South Korea, Hong Kong, Taiwan, Japan and Australia: An observational, descriptive study

Brauer, R., Wong, I. C. K., Man, K. K. C., Pratt, N. L., Park, R. W., Cho, S. Y., Li, Y. C., Iqbal, U., Nguyen, P. A. A. & Schuemie, M., Jan 13 2020, In : BMJ Open. 10, 1, p. e032426 032426.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

A shrimp glycosylase protein, PmENGase, interacts with WSSV envelope protein VP41B and is involved in WSSV pathogenesis

Huang, J. Y., Wang, H. C., Chen, Y. C., Wang, P. S., Lin, S. J., Chang, Y. S., Liu, K. F. & Lo, C. F., Jul 2020, In : Developmental and Comparative Immunology. 108, 103667.

Research output: Contribution to journalArticle

Open Access

Association between benzodiazepines use and risk of hip fracture in the elderly people: A meta-analysis of observational studies

Poly, T. N., Islam, M. M., Yang, H. C. & Li, Y. C. J., Mar 2020, In : Joint Bone Spine. 87, 3, p. 241-249

Research output: Contribution to journalArticle

1 Citation (Scopus)

Computational analysis for identification of the extracellular matrix molecules involved in endometrial cancer progression

Yadav, V. K., Lee, T. Y., Hsu, J. B. K., Huang, H. D., Yang, W. C. V. & Chang, T. H., Apr 2020, In : PLoS ONE. 15, 4, e0231594.

Research output: Contribution to journalArticle

Open Access

Macrophages protect mycoplasma-infected chronic myeloid leukemia cells from natural killer cell killing

Choo, Q. W. W., Koean, R. A. G., Chang, S. C., Chng, W. J., Chan, M. C., Wang, W., Er, J. Z. & Ding, J. L., Feb 1 2020, In : Immunology and Cell Biology. 98, 2, p. 138-151 14 p.

Research output: Contribution to journalArticle

Open Access

Microtube array membrane (MTAM)-based encapsulated cell therapy for cancer treatment

Chew, C. H., Lee, C. W., Huang, W. T., Cheng, L. W., Chen, A., Cheng, T. M., Liu, Y. L. & Chen, C. C., May 2020, In : Membranes. 10, 5, 80.

Research output: Contribution to journalArticle

Open Access
Open Access

Ovatodiolide suppresses oral cancer malignancy by down-regulating exosomal mir-21/STAT3/β-catenin cargo and preventing oncogenic transformation of normal gingival fibroblasts

Chen, J. H., Wu, A. T. H., Bamodu, O. A., Yadav, V. K., Chao, T. Y., Tzeng, Y. M., Mukhopadhyay, D., Hsiao, M. & Lee, J. C., Jan 2020, In : Cancers. 12, 1, 56.

Research output: Contribution to journalArticle

Open Access

Predicting Lung Cancer Occurrence in Never-Smoking Females in Asia: TNSF-SQ, a Prediction Model

Chien, L. H., Chen, C. H., Chen, T. Y., Chang, G. C., Tsai, Y. H., Hsiao, C. F., Chen, K. Y., Su, W. C., Wang, W. C., Huang, M. S., Chen, Y. M., Chen, C. Y., Liang, S. K., Chen, C. Y., Wang, C. L., Lee, M. H., Chung, R. H., Tsai, F. Y., Hu, J. W., Katki, H. A. & 8 others, Chatterjee, N., Chanock, S. J., Rothman, N., Lan, Q., Yang, P. C., Chen, C. J., Chang, I. S. & Hsiung, C. A., Feb 1 2020, In : Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 29, 2, p. 452-459 8 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Predictive value of genetic variants XRCC1 rs1799782, APEX1 rs1760944, and MUTYH rs3219489 for adjuvant concurrent chemoradiotherapy outcomes in oral squamous cell carcinoma patients

Senghore, T., Chien, H. T., Wang, W. C., Chen, Y. X., Young, C. K., Huang, S. F. & Yeh, C. C., 2020, (Accepted/In press) In : Pharmacogenomics Journal.

Research output: Contribution to journalArticle

Structural insight into the differential interactions between the DNA mimic protein SAUGI and two gamma herpesvirus uracil-DNA glycosylases

Liao, Y. T., Lin, S. J., Ko, T. P., Liu, C. Y., Hsu, K. C. & Wang, H. C., Oct 1 2020, In : International Journal of Biological Macromolecules. 160, p. 903-914 12 p.

Research output: Contribution to journalArticle

Tandem mach zehnder directional coupler design and simulation on silicon platform for optical coherence tomography applications

Lu, Y. T., Widhianto, B. Y. B., Hsu, S. H. & Chang, C. C., Feb 2 2020, In : Sensors (Switzerland). 20, 4, 1054.

Research output: Contribution to journalArticle

Open Access
Open Access

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

Wong, J. Y. Y., Zhang, H., Hsiung, C. A., Shiraishi, K., Yu, K., Matsuo, K., Wong, M. P., Hong, Y. C., Wang, J., Seow, W. J., Wang, Z., Song, M., Kim, H. N., Chang, I. S., Chatterjee, N., Hu, W., Wu, C., Mitsudomi, T., Zheng, W., Kim, J. H. & 166 others, Seow, A., Caporaso, N. E., Shin, M. H., Chung, L. P., An, S. J., Wang, P., Yang, Y., Zheng, H., Yatabe, Y., Zhang, X. C., Kim, Y. T., Cai, Q., Yin, Z., Kim, Y. C., Bassig, B. A., Chang, J., Ho, J., Ji, B. T., Daigo, Y., Ito, H., Momozawa, Y., Ashikawa, K., Kamatani, Y., Honda, T., Hosgood, H. D., Sakamoto, H., Kunitoh, H., Tsuta, K., Watanabe, S. I., Kubo, M., Miyagi, Y., Nakayama, H., Matsumoto, S., Tsuboi, M., Goto, K., Shi, J., Song, L., Hua, X., Takahashi, A., Goto, A., Minamiya, Y., Shimizu, K., Tanaka, K., Wei, F., Matsuda, F., Su, J., Kim, Y. H., Oh, I. J., Song, F., Su, W. C., Chen, Y. M., Chang, G. C., Chen, K. Y., Huang, M. S., Chien, L. H., Xiang, Y. B., Park, J. Y., Kweon, S. S., Chen, C. J., Lee, K. M., Blechter, B., Li, H., Gao, Y. T., Qian, B., Lu, D., Liu, J., Jeon, H. S., Hsiao, C. F., Sung, J. S., Tsai, Y. H., Jung, Y. J., Guo, H., Hu, Z., Wang, W. C., Chung, C. C., Burdett, L., Yeager, M., Hutchinson, A., Berndt, S. I., Wu, W., Pang, H., Li, Y., Choi, J. E., Park, K. H., Sung, S. W., Liu, L., Kang, C. H., Zhu, M., Chen, C. H., Yang, T. Y., Xu, J., Guan, P., Tan, W., Wang, C. L., Hsin, M., Sit, K. Y., Ho, J., Chen, Y., Choi, Y. Y., Hung, J. Y., Kim, J. S., Yoon, H. I., Lin, C. C., Park, I. K., Xu, P., Wang, Y., He, Q., Perng, R. P., Chen, C. Y., Vermeulen, R., Wu, J., Lim, W. Y., Chen, K. C., Li, Y. J., Li, J., Chen, H., Yu, C. J., Jin, L., Chen, T. Y., Jiang, S. S., Liu, J., Yamaji, T., Hicks, B., Wyatt, K., Li, S. A., Dai, J., Ma, H., Jin, G., Song, B., Wang, Z., Cheng, S., Li, X., Ren, Y., Cui, P., Iwasaki, M., Shimazu, T., Tsugane, S., Zhu, J., Yang, K., Jiang, G., Fei, K., Wu, G., Lin, H. C., Chen, H. L., Fang, Y. H., Tsai, F. Y., Hsieh, W. S., Yu, J., Stevens, V. L., Laird-Offringa, I. A., Marconett, C. N., Rieswijk, L., Chao, A., Yang, P. C., Shu, X. O., Wu, T., Wu, Y. L., Lin, D., Chen, K., Zhou, B., Huang, Y. C., Kohno, T., Shen, H., Chanock, S. J., Rothman, N. & Lan, Q., Mar 2020, In : Genomics. 112, 2, p. 1223-1232 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access

Two new, near-infrared, fluorescent probes as potential tools for imaging bone repair

Lin, C. C., Chang, W. H. S., Cheng, T. M., Chiu, L. H., Wang, Y. H., Lin, C. A. J., Ho, Y. S., Zuo, C. S., Wang, Y. M. & Lai, W. F. T., Dec 1 2020, In : Scientific Reports. 10, 1, 2580.

Research output: Contribution to journalArticle

Open Access

Upregulation of Cisd2 attenuates Alzheimer's-related neuronal loss in mice

Chen, Y. F., Chou, T. Y., Lin, I. H., Chen, C. G., Kao, C. H., Huang, G. J., Chen, L. K., Wang, P. N., Lin, C. P. & Tsai, T. F., Mar 1 2020, In : Journal of Pathology. 250, 3, p. 299-311 13 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2019

Adipose-derived Stem Cells Attenuates Diabetic Osteoarthritis via Inhibition of Glycation-mediated Inflammatory Cascade

Dubey, N. K., Wei, H-J., Yu, S. H., Williams, D. F., Wang, J. R., Deng, Y. H., Tsai, F. C., Wang, D. P. & Deng, W-P., 2019, In : Aging and Disease.

Research output: Contribution to journalArticle

Open Access

An artificial intelligence approach to early predict non-ST-elevation myocardial infarction patients with chest pain

Wu, C. C., Hsu, W. D., Islam, M. M., Poly, T. N., Yang, H. C., Nguyen, P. AA., Wang, Y. C. & Li, Y. CJ., May 1 2019, In : Computer Methods and Programs in Biomedicine. 173, p. 109-117 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Antrocin, a bioactive component from Antrodia cinnamomea, suppresses breast carcinogenesis and stemness via downregulation of β-catenin/Notch1/Akt signaling

Chen, J. H., T.H Wu, A., T.W Tzeng, D., Huang, C. C., Tzeng, Y. M. & Chao, T. Y., Jan 1 2019, In : Phytomedicine. 52, p. 70-78 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A probabilistic model for reducing medication errors: A sensitivity analysis using Electronic Health Records data

Huang, C. Y., Nguyen, P. A., Yang, H. C., Islam, M. M., Liang, C. W., Lee, F. P. & (Jack) Li, Y. C., Mar 1 2019, In : Computer Methods and Programs in Biomedicine. 170, p. 31-38 8 p.

Research output: Contribution to journalArticle

Association between gout and cardiovascular disease risk: A nation-wide case-control study

Liang, C-W., Islam, M. M., Poly, T. N., Yang, H-C. & Jack Li, Y-C., May 2019, In : Joint Bone Spine.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Association of chronic hepatitis B virus infection with age-related macular degeneration

Wu, C. M., Su, F. H., Wang, W. C., Lin, C. P., Kamiza, A. B., Chang, S. N. & Yeh, C. C., Aug 2019, In : Acta Ophthalmologica. 97, 5, p. e713-e718

Research output: Contribution to journalArticle

2 Citations (Scopus)
Open Access
8 Citations (Scopus)

Cellular Magnetic Resonance Imaging with Superparamagnetic Iron Oxide: Methods and Applications in Cancer

Hsu, F. T., Sun, R. & Hsieh, C. L., Jan 1 2019, In : SPIN.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation

Lai, S. C., Su, Y. T., Chi, C. C., Kuo, Y. C., Lee, K. F., Wu, Y. C., Lan, P. C., Yang, M. H., Chang, T. S. & Huang, Y. H., Nov 26 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 474.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
Open Access

Effect of Preoperative Dutasteride on Holmium Laser Enucleation of the Prostate

Shigemura, K., Kitagawa, K., Chen, K. C., Sung, S. Y. & Fujisawa, M., Jan 1 2019, (Accepted/In press) In : Urologia Internationalis.

Research output: Contribution to journalArticle

Fluorine-Modified Rutaecarpine Exerts Cyclooxygenase-2 Inhibition and Anti-inflammatory Effects in Lungs

Lee, C., Liao, J., Chen, S., Yen, C., Lee, Y., Huang, S., Huang, S., Lin, C. M. & Chang, V. H., 2019, In : Frontiers in Pharmacology. 10, p. 91

Research output: Contribution to journalArticle

5 Citations (Scopus)
Open Access

Gonadotropin-releasing hormone agonist induces downregulation of tensin 1 in women with endometriosis

Rahmawati, E., Yang, W. C. V., Lei, Y. P., Maurya, P. K., Chen, H. W. & Tzeng, C. R., Feb 1 2019, In : Acta Obstetricia et Gynecologica Scandinavica. 98, 2, p. 222-231 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access

Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 06 Biological Sciences 0601 Biochemistry and Cell Biology

Hung, P. F., Hong, T. M., Chang, C. C., Hung, C. L., Hsu, Y. L., Chang, Y. L., Wu, C. T., Chang, G. C., Chan, N. L., Yu, S. L., Yang, P. C. & Pan, S. H., Jan 6 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 5.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Increase Risk of Multiple Sclerosis in Patients with Psoriasis Disease: An Evidence of Observational Studies

Islam, M. M., Poly, T. N., Yang, H. C., Wu, C. C. & Li, Y. C., Jan 1 2019, (Accepted/In press) In : Neuroepidemiology. p. 152-160 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non-small-cell lung cancer

Huang, T-H., Wu, A. T. H., Cheng, T-S., Lin, K-T., Lai, C-J., Hsieh, H-W., Chang, P. M-H., Wu, C-W., Huang, C-Y. F. & Chen, K-Y., Oct 22 2019, In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

4 Citations (Scopus)
4 Citations (Scopus)

KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC

Wang, H. J., Pochampalli, M., Wang, L. Y., Zou, J. X., Li, P. S., Hsu, S. C., Wang, B. J., Huang, S. H., Yang, P., Yang, J. C., Chu, C. Y., Hsieh, C. L., Sung, S. Y., Li, C. F., Tepper, C. G., Ann, D. K., Gao, A. C., Evans, C. P., Izumiya, Y., Chuu, C. P. & 3 others, Wang, W. C., Chen, H. W. & Kung, H. J., Jan 3 2019, In : Oncogene. 38, 1, p. 17-32

Research output: Contribution to journalArticle

12 Citations (Scopus)
14 Citations (Scopus)

Patients with chronic urticaria have a higher risk of psychiatric disorders: a population-based study

Chu, C. Y., Cho, Y. T., Jiang, J. H., Chang, C. C., Liao, S. C. & Tang, C-H., 2019, In : British Journal of Dermatology. 182, 2, p. 335-341

Research output: Contribution to journalArticle

1 Citation (Scopus)