The Ph.D. Program for Translational Medicine

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1995 2019

2019

Adipose-derived Stem Cells Attenuates Diabetic Osteoarthritis via Inhibition of Glycation-mediated Inflammatory Cascade

Dubey, N. K., Wei, H-J., Yu, S. H., Williams, D. F., Wang, J. R., Deng, Y. H., Tsai, F. C., Wang, D. P. & Deng, W-P., 2019, In : Aging and Disease.

Research output: Contribution to journalArticle

Osteoarthritis
Stem Cells
Knee Joint
Advanced Glycosylation End Products
NF-kappa B

An artificial intelligence approach to early predict non-ST-elevation myocardial infarction patients with chest pain

Wu, C. C., Hsu, W. D., Islam, M. M., Poly, T. N., Yang, H. C., Nguyen, P. AA., Wang, Y. C. & Li, Y. CJ., May 1 2019, In : Computer Methods and Programs in Biomedicine. 173, p. 109-117 9 p.

Research output: Contribution to journalArticle

Artificial Intelligence
Chest Pain
Artificial intelligence
Neural networks
Neural Networks (Computer)
Castration
Autophagy
Prostatic Neoplasms
Cell Death
Osteogenesis
1 Citation (Scopus)

Antrocin, a bioactive component from Antrodia cinnamomea, suppresses breast carcinogenesis and stemness via downregulation of β-catenin/Notch1/Akt signaling

Chen, J. H., T.H Wu, A., T.W Tzeng, D., Huang, C. C., Tzeng, Y. M. & Chao, T. Y., Jan 1 2019, In : Phytomedicine. 52, p. 70-78 9 p.

Research output: Contribution to journalArticle

Antrodia
Catenins
Carcinogenesis
Breast
Down-Regulation

A positive legacy of trauma? A study on the impact of natural disasters on medical utilization

Iqbal, U., Li, Y-C. J., Tang, K-P., Chien, H-C., Yang, Y-T. & Hsu, Y-H. E., Feb 1 2019, In : International Journal for Quality in Health Care. 31, 1, p. 64-69 6 p.

Research output: Contribution to journalReview article

Earthquakes
Disasters
Survivors
Wounds and Injuries
Outpatients

A probabilistic model for reducing medication errors: A sensitivity analysis using Electronic Health Records data

Huang, C. Y., Nguyen, P. A., Yang, H. C., Islam, M. M., Liang, C. W., Lee, F. P. & (Jack) Li, Y. C., Mar 1 2019, In : Computer Methods and Programs in Biomedicine. 170, p. 31-38 8 p.

Research output: Contribution to journalArticle

Medication Errors
Electronic Health Records
Statistical Models
Sensitivity analysis
Prescriptions
1 Citation (Scopus)

Association between gout and cardiovascular disease risk: A nation-wide case-control study

Liang, C-W., Islam, M. M., Poly, T. N., Yang, H-C. & Jack Li, Y-C., May 2019, In : Joint Bone Spine.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Association of chronic hepatitis B virus infection with age-related macular degeneration

Wu, C. M., Su, F. H., Wang, W. C., Lin, C. P., Kamiza, A. B., Chang, S. N. & Yeh, C. C., Jan 1 2019, In : Acta Ophthalmologica.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Macular Degeneration
Virus Diseases
Hepatitis B virus
Cercopithecine Herpesvirus 1
1 Citation (Scopus)
Open Access
Astragalus
dendritic cells
lung neoplasms
Dendritic Cells
Polysaccharides
AMP-Activated Protein Kinases
Epithelial-Mesenchymal Transition
Hypoxia-Inducible Factor 1
Colonic Neoplasms
Colorectal Neoplasms

Cancers in Taiwan: Practical insight from epidemiology, treatments, biomarkers, and cost

Kuo, C. N., Liao, Y. M., Kuo, L. N., Tsai, H. J., Chang, W. C. & Yen, Y., Jan 1 2019, (Accepted/In press) In : Journal of the Formosan Medical Association.

Research output: Contribution to journalReview article

Open Access
Taiwan
Health Care Costs
Epidemiology
Biomarkers
Therapeutic Uses

Cellular Magnetic Resonance Imaging with Superparamagnetic Iron Oxide: Methods and Applications in Cancer

Hsu, F. T., Sun, R. & Hsieh, C. L., Jan 1 2019, In : SPIN.

Research output: Contribution to journalArticle

Iron oxides
iron oxides
magnetic resonance
cancer
Magnetic resonance
Open Access
hormones
Nerve Growth Factors
releasing
Endometriosis
Gonadotropin-Releasing Hormone
Patient Care
Learning
Deep learning

Development of deep learning algorithm for detection of colorectal cancer in EHR data

Wang, Y. H., Nguyen, P. A., Mohaimenul Islam, M., Li, Y. C. & Yang, H. C., Aug 21 2019, MEDINFO 2019: Health and Wellbeing e-Networks for All - Proceedings of the 17th World Congress on Medical and Health Informatics. Seroussi, B., Ohno-Machado, L., Ohno-Machado, L. & Seroussi, B. (eds.). IOS Press, p. 438-441 4 p. (Studies in Health Technology and Informatics; vol. 264).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Learning algorithms
Colorectal Neoplasms
Learning
Area Under Curve
Sensitivity and Specificity
5 Citations (Scopus)
Robotics
Rectal Neoplasms
Laparoscopy
Meta-Analysis
Randomized Controlled Trials
1 Citation (Scopus)

Fluorine-Modified Rutaecarpine Exerts Cyclooxygenase-2 Inhibition and Anti-inflammatory Effects in Lungs

Lee, C., Liao, J., Chen, S., Yen, C., Lee, Y., Huang, S., Huang, S., Lin, C. M. & Chang, V. H., 2019, In : Frontiers in Pharmacology. 10, p. 91

Research output: Contribution to journalArticle

Fluorine
Cyclooxygenase 2
Anti-Inflammatory Agents
Lung
Myofibroblasts
Open Access
Cell Cycle Proteins
Epithelial-Mesenchymal Transition
regulators
Prostatic Neoplasms
genes
3 Citations (Scopus)

Gonadotropin-releasing hormone agonist induces downregulation of tensin 1 in women with endometriosis

Rahmawati, E., Yang, W. C. V., Lei, Y. P., Maurya, P. K., Chen, H. W. & Tzeng, C. R., Feb 1 2019, In : Acta Obstetricia et Gynecologica Scandinavica. 98, 2, p. 222-231 10 p.

Research output: Contribution to journalArticle

Endometriosis
Gonadotropin-Releasing Hormone
Down-Regulation
Serum
Cell Movement
Reducing Diet
Haptoglobins
Phenotype
Waist Circumference
Abdominal Obesity
1 Citation (Scopus)
Quality of Health Care

Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers

Chen, Y. F., Wang, Y. H., Lei, C. S., Changou, C. A., Davis, M. E. & Yen, Y., Oct 23 2019, In : Journal of Biomedical Science. 26, 1, 1 p.

Research output: Contribution to journalReview article

Open Access
Camptothecin
Cyclodextrins
Polymers
Neoplasms
Nanoparticles
2 Citations (Scopus)

Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 06 Biological Sciences 0601 Biochemistry and Cell Biology

Hung, P. F., Hong, T. M., Chang, C. C., Hung, C. L., Hsu, Y. L., Chang, Y. L., Wu, C. T., Chang, G. C., Chan, N. L., Yu, S. L., Yang, P. C. & Pan, S. H., Jan 6 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 5.

Research output: Contribution to journalArticle

Sumoylation
Gastropoda
Biological Science Disciplines
Biochemistry
Cell Biology

Increase Risk of Multiple Sclerosis in Patients with Psoriasis Disease: An Evidence of Observational Studies

Islam, M. M., Poly, T. N., Yang, H. C., Wu, C. C. & Li, Y. C., Jan 1 2019, (Accepted/In press) In : Neuroepidemiology. p. 152-160 9 p.

Research output: Contribution to journalArticle

Psoriasis
Multiple Sclerosis
Observational Studies
Bibliography
PubMed

In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non-small-cell lung cancer

Huang, T-H., Wu, A. T. H., Cheng, T-S., Lin, K-T., Lai, C-J., Hsieh, H-W., Chang, P. M-H., Wu, C-W., Huang, C-Y. F. & Chen, K-Y., Oct 22 2019, In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

Thiostrepton
Neoplastic Stem Cells
Non-Small Cell Lung Carcinoma
Computer Simulation
Drug Therapy
2 Citations (Scopus)
Regulatory T-Lymphocytes
Adenoviridae
Dendritic Cells
Asthma
Ovalbumin
4 Citations (Scopus)

KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC

Wang, H. J., Pochampalli, M., Wang, L. Y., Zou, J. X., Li, P. S., Hsu, S. C., Wang, B. J., Huang, S. H., Yang, P., Yang, J. C., Chu, C. Y., Hsieh, C. L., Sung, S. Y., Li, C. F., Tepper, C. G., Ann, D. K., Gao, A. C., Evans, C. P., Izumiya, Y., Chuu, C. P. & 3 others, Wang, W. C., Chen, H. W. & Kung, H. J., Jan 3 2019, In : Oncogene. 38, 1, p. 17-32

Research output: Contribution to journalArticle

Pyruvate Kinase
Androgen Receptors
Androgens
Castration
Prostatic Neoplasms
2 Citations (Scopus)

New paradigm of functional regulation by DNA mimic proteins: Recent updates

Wang, H. C., Chou, C. C., Hsu, K. C., Lee, C. H. & Wang, A. H. J., May 1 2019, In : IUBMB Life. 71, 5, p. 539-548 10 p.

Research output: Contribution to journalReview article

DNA
Charge distribution
Proteins
Clustered Regularly Interspaced Short Palindromic Repeats
Uracil-DNA Glycosidase
3 Citations (Scopus)
Parkinson Disease
Meta-Analysis
Anti-Inflammatory Agents
Pharmaceutical Preparations
Population
Taiwan
Learning
Health
Community Health Planning
Electronic Health Records

Osteonectin promoter-mediated suicide gene therapy of prostate cancer

Hsiao, W. C., Sung, S. Y., Chung, L. W. K. & Hsieh, C. L., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 27-42 16 p. (Methods in Molecular Biology; vol. 1895).

Research output: Chapter in Book/Report/Conference proceedingChapter

Osteonectin
Thymidine Kinase
Simplexvirus
Genetic Therapy
Suicide

Patients with chronic urticaria have a higher risk of psychiatric disorders: a population-based study

Chu, C. Y., Cho, Y. T., Jiang, J. H., Chang, C. C., Liao, S. C. & Tang, C-H., Jan 1 2019, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

Urticaria
Psychiatry
Population
Prescriptions
Outpatients

Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces cyclooxygenase-2 expression in gastric adenocarcinoma cells

Wong, J. H., Wang, Y. S., Nam, S., Ho, K. H., Chang, C. M., Chen, K. C., Chen, Y. F. & Chang, W. C., Jan 1 2019, In : Environmental Toxicology.

Research output: Contribution to journalArticle

Plasticizers
phthalate
Cyclooxygenase 2
Stomach
Adenocarcinoma

Plasma haptoglobin level can augment NT-proBNP to predict poor outcome in patients with severe acute decompensated heart failure

Lu, D. Y., Lin, C. P., Wu, C. H., Cheng, T. M. & Pan, J. P., Jan 2019, In : Journal of Investigative Medicine.

Research output: Contribution to journalArticle

Haptoglobins
Brain Natriuretic Peptide
Heart Failure
Plasmas
Survival
Adjuvant Chemoradiotherapy
Chemoradiotherapy
DNA Repair
Squamous Cell Carcinoma
Genotype

Polymorphisms of Mismatch Repair Pathway Genes Predict Clinical Outcomes in Oral Squamous Cell Carcinoma Patients Receiving Adjuvant Concurrent Chemoradiotherapy

Senghore, T., Wang, W-C., Chien, H-T., Chen, Y-X., Young, C-K., Huang, S-F. & Yeh, C-C., Apr 29 2019, In : Cancers. 11, 5

Research output: Contribution to journalArticle

Adjuvant Chemoradiotherapy
DNA Mismatch Repair
Chemoradiotherapy
Squamous Cell Carcinoma
Genotype
Hedgehogs
Urinary Bladder Neoplasms
Hedgehog Proteins
Muscles
Cadherins
2 Citations (Scopus)

Prediction of fatty liver disease using machine learning algorithms

Wu, C. C., Yeh, W. C., Hsu, W. D., Islam, M. M., Nguyen, P. AA., Poly, T. N., Wang, Y. C., Yang, H. C. & (Jack) Li, Y. C., Mar 1 2019, In : Computer Methods and Programs in Biomedicine. 170, p. 23-29 7 p.

Research output: Contribution to journalArticle

Fatty Liver
Liver
Learning algorithms
Learning systems
Liver Diseases
6 Citations (Scopus)

Prediction of sepsis patients using machine learning approach: A meta-analysis

Islam, M. M., Nasrin, T., Walther, B. A., Wu, C. C., Yang, H. C. & Li, Y. C., Mar 1 2019, In : Computer Methods and Programs in Biomedicine. 170, p. 1-9 9 p.

Research output: Contribution to journalArticle

Learning systems
Meta-Analysis
Sepsis
Learning algorithms
Machine Learning
10 Citations (Scopus)

Proton pump inhibitors and risk of hip fracture: a meta-analysis of observational studies

Poly, T. N., Islam, M. M., Yang, H. C., Wu, C. C. & Li, Y. C. . J. ., Jan 18 2019, In : Osteoporosis International. 30, 1, p. 103-114 12 p.

Research output: Contribution to journalArticle

Proton Pump Inhibitors
Hip Fractures
Observational Studies
Meta-Analysis
Therapeutics
1 Citation (Scopus)

RAB27B-activated secretion of stem-like tumor exosomes delivers the biomarker microRNA-146a-5p, which promotes tumorigenesis and associates with an immunosuppressive tumor microenvironment in colorectal cancer

Cheng, W. C., Liao, T. T., Lin, C. C., Yuan, L. T. E., Lan, H. Y., Lin, H. H., Teng, H. W., Chang, H. C., Lin, C. H., Yang, C. Y., Huang, S. C., Jiang, J. K., Yang, S. H., Yang, M. H. & Hwang, W. L., Jan 1 2019, In : International Journal of Cancer.

Research output: Contribution to journalArticle

Exosomes
Tumor Microenvironment
Immunosuppressive Agents
MicroRNAs
Neoplastic Stem Cells
Haptoglobins
Chronic Obstructive Pulmonary Disease
Inflammation
Phenotype
Alveolar Epithelial Cells
Endometriosis
Biomarkers
Proteins
Therapeutics

Response to letter: 'Proton pump inhibitors therapy and the risk of major osteoporotic nonhip fractures in older adults in Taiwan'

Islam, M. M., Poly, T. N., Walther, B. A., Dubey, N. K., Ningrum, D. N. A., Syed-Abdul, S. & Li, Y. C. J., Feb 1 2019, In : European journal of gastroenterology & hepatology. 31, 2, 1 p.

Research output: Contribution to journalArticle

Osteoporotic Fractures
Proton Pump Inhibitors
Taiwan
Therapeutics

Risk of acute myocardial infarction in patients with rheumatic arthritis: A national-wide population-based cohort study

Mohaimenul Islam, M., Poly, T. N., Yang, H. C. & Li, Y. C., Aug 21 2019, MEDINFO 2019: Health and Wellbeing e-Networks for All - Proceedings of the 17th World Congress on Medical and Health Informatics. Seroussi, B., Ohno-Machado, L., Ohno-Machado, L. & Seroussi, B. (eds.). IOS Press, p. 1494-1495 2 p. (Studies in Health Technology and Informatics; vol. 264).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Rheumatic Fever
Cohort Studies
Myocardial Infarction
Population
International Classification of Diseases
Anthracyclines
Radiotherapy
Breast Neoplasms
Drug Therapy
Adjuvant Radiotherapy

Rrm2b deletion causes mitochondrial metabolic defects in renal tubules

Chen, Y. F., Lin, I. H., Guo, Y. R., Chiu, W. J., Wu, M. S., Jia, W. & Yen, Y., Sep 13 2019, In : Scientific Reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Kidney
Mitochondria
Kidney Diseases
DNA Replication
Knockout Mice
2 Citations (Scopus)

Structural insights to the heterotetrameric interaction between the vibrio parahaemolyticus pirA vp and pirB vp toxins and activation of the cry-like pore-forming domain

Lin, S. J., Chen, Y. F., Hsu, K. C., Chen, Y. L., Ko, T. P., Lo, C. F., Wang, H. C. & Wang, H. C., Apr 1 2019, In : Toxins. 11, 4, 233.

Research output: Contribution to journalArticle

Open Access
Vibrio parahaemolyticus
Penaeidae
Chemical activation
Necrosis
Hepatopancreas
Open Access
Petroselinum
G1 Phase Cell Cycle Checkpoints
Cell Cycle Resting Phase
G1 Phase
Nude Mice