The Ph.D. Program for Neural Regenerative Medicine

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 2000 2019

Article

MR imaging central thalamic deep brain stimulation restored autistic-like social deficits in the rat

Lin, T. C., Lo, Y. C., Lin, H. C., Li, S. J., Lin, S. H., Wu, H. F., Chu, M. C., Lee, C. W., Lin, I. C., Chang, C. W., Liu, Y. C., Chen, T. C., Lin, Y. J., Ian Shih, Y. Y. & Chen, Y. Y., Jan 1 2019, In : Brain Stimulation.

Research output: Contribution to journalArticle

Deep Brain Stimulation
Thalamic Nuclei
Magnetic Resonance Imaging
Interpersonal Relations
Brain
4 Citations (Scopus)
Taiwan
Breast Neoplasms
DNA Mismatch Repair
Single Nucleotide Polymorphism
Luciferases
7 Citations (Scopus)

Nano-diamino-tetrac (NDAT) inhibits PD-L1 expression which is essential for proliferation in oral cancer cells

Lin, S. J., Chin, Y. T., Ho, Y., Chou, S. Y., Sh Yang, Y. C., Nana, A. W., Su, K. W., Lim, Y. T., Wang, K., Lee, SY. Y., Shih, Y. J., Chen, Y. R., Whang-Peng, J., Davis, P. J., Lin, H. Y. & Fu, E., Oct 1 2018, In : Food and Chemical Toxicology. 120, p. 1-11 11 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Cells
death
Ligands
phosphatidylinositol 3-kinase

Nck2 is essential for limb trajectory selection by spinal motor axons

Chang, C. J., Chang, M. Y., Lee, Y. C., Chen, K. Y., Hsu, T. I., Wu, Y. H., Chuang, J. Y. & Kao, T. J., Sep 1 2018, In : Developmental Dynamics. 247, 9, p. 1043-1056 14 p.

Research output: Contribution to journalArticle

Axons
Extremities
Motor Neurons
Ephrins
Neurites
62 Citations (Scopus)

Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord

Varadarajan, S. G., Kong, J. H., Phan, K. D., Kao, T. J., Panaitof, S. C., Cardin, J., Eltzschig, H., Kania, A., Novitch, B. G. & Butler, S. J., May 17 2017, In : Neuron. 94, 4, p. 790-799.e3

Research output: Contribution to journalArticle

Axons
Spinal Cord
Chemotactic Factors
Chemotaxis
Growth
3 Citations (Scopus)

Neurovascular function recovery after focal ischemic stroke by enhancing cerebral collateral circulation via peripheral stimulation-mediated interarterial anastomosis

Pan, H-C., Liao, L-D., Lo, Y-C., Chen, J-W., Wang, H-L., Yang, L., Liang, Y-W., Huang, P-Y., Yang, M-H. & Chen, Y-Y., Jul 2017, In : Neurophotonics. 4, 3, p. 035003

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Collateral Circulation
Forelimb
Recovery of Function
Stroke

Nicotine-induced conditional place preference is affected by head injury: Correlation with dopamine release in the nucleus accumbens shell

Chen, Y. H., Kuo, T. T., Huang, E. Y. K., Hoffer, B. J., Kao, J. H., Chou, Y. C., Chiang, Y. H. & Miller, J., Oct 1 2018, In : International Journal of Neuropsychopharmacology. 21, 10, p. 949-961 13 p.

Research output: Contribution to journalArticle

Nucleus Accumbens
Nicotine
Craniocerebral Trauma
Dopamine
Percussion
1 Citation (Scopus)

Nm23-H1-stabilized hnRNPA2/B1 promotes internal ribosomal entry site (IRES)-mediated translation of Sp1 in the lung cancer progression

Hung, C. Y., Wang, Y. C., Chuang, J. Y., Young, M. J., Liaw, H., Chang, W. C. & Hung, J. J., Dec 1 2017, In : Scientific Reports. 7, 1, 9166.

Research output: Contribution to journalArticle

Protein Biosynthesis
Lung Neoplasms
Proteins
Messenger RNA
Protein Stability
2 Citations (Scopus)
Coumarins
Cell death
Colonic Neoplasms
Cell Death
Cells
6 Citations (Scopus)

Novel use of theta burst cortical electrical stimulation for modulating motor plasticity in rats

Hsieh, T. H., Huang, Y. Z., Chen, J. J. J., Rotenberg, A., Chiang, Y-H., Chien, W. S. C., Chang, H-S., Wang, J-Y. & Peng, C-W., Feb 1 2015, In : Journal of Medical and Biological Engineering. 35, 1, p. 62-68 7 p.

Research output: Contribution to journalArticle

Motor Evoked Potentials
Electric Stimulation
Plasticity
Rats
Motor Cortex

One world for public health education

Flahault, A., Chiu, W. T., Rosenstock, L., Chiang, T. L., Patrick, W. K. & Chang, P. W. S., Oct 2010, In : Journal of Experimental and Clinical Medicine(Taiwan). 2, 5, p. 200-201 2 p.

Research output: Contribution to journalArticle

Health Education
Public Health
Global Health
10 Citations (Scopus)
ovarian neoplasms
Centromere
centromeres
Ovarian Neoplasms
Tumor Biomarkers
15 Citations (Scopus)

Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability

Huang, C. L., Chao, C. C., Lee, Y. C., Lu, M. K., Cheng, J. J., Yang, Y. C., Wang, V. C., Chang, W. C. & Huang, N. K., 2016, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Paraquat
Mitochondrial Membranes
Permeability
Cell Death
Apoptosis
3 Citations (Scopus)

PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model

Chiu, C. C., Lu, C. S., Weng, Y. H., Chen, Y. L., Huang, Y. Z., Chen, R. S., Cheng, Y. C., Huang, Y. C., Liu, Y. C., Lai, S. C., Lin, K. J., Lin, Y. W., Chen, Y. J., Chen, C. L., Yeh, T. H. & Wang, H. L., Jan 1 2018, (Accepted/In press) In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Dopaminergic Neurons
Substantia Nigra
Mutation
Parkinson Disease
9 Citations (Scopus)

PARK14 PLA2G6 mutants are defective in preventing rotenoneinduced mitochondrial dysfunction, ROS generation and activation of mitochondrial apoptotic pathway

Chiu, C. C., Yeh, T. H., Lu, C. S., Huang, Y. C., Cheng, Y. C., Huang, Y. Z., Weng, Y. H., Liu, Y. C., Lai, S. C., Chen, Y. L., Chen, Y. J., Chen, C. L., Chen, H. Y., Lin, Y. W. & Wang, H. L., 2017, In : Oncotarget. 8, 45, p. 79046-79060 15 p.

Research output: Contribution to journalArticle

Phospholipases A2
Rotenone
Parkinson Disease
Mitochondrial Degradation
Mitochondrial Membrane Potential
14 Citations (Scopus)

Pb2+ induced IL-8 gene expression by extracellular signal-regulated kinases and the transcription factor, activator protein 1, in human gastric carcinoma cells

Lin, Y. C., Wei, P. L., Tsai, Y. T., Wong, J. H., Chang, C. M., Wang, J. Y., Hou, M. F., Lee, Y. C., Chuang, H. Y. & Chang, W. C., Mar 1 2015, In : Environmental Toxicology. 30, 3, p. 315-322 8 p.

Research output: Contribution to journalArticle

Extracellular Signal-Regulated MAP Kinases
Transcription Factor AP-1
Interleukin-8
Gene expression
gene expression
26 Citations (Scopus)

Pediatric traumatic brain injuries in Taiwan: An 8-year study

Tsai, W. C., Chiu, W. T., Chiou, H. Y., Choy, C-S., Hung, C. C. & Tsai, S. H., Feb 2004, In : Journal of Clinical Neuroscience. 11, 2, p. 126-129 4 p.

Research output: Contribution to journalArticle

Taiwan
Pediatrics
Wounds and Injuries
Age Groups
Motorcycles
17 Citations (Scopus)
Proteolysis
Lung Neoplasms
Carcinogenesis
Phosphorylation
Acetylation
9 Citations (Scopus)

Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis

Yang, H. C., Chuang, J. Y., Jeng, W. Y., Liu, C. I., Wang, A. H. J., Lu, P. J., Chang, W. C. & Hung, J. J., Dec 16 2014, In : Nucleic Acids Research. 42, 22, p. 13573-13587 15 p.

Research output: Contribution to journalArticle

Mitosis
Phosphorylation
DNA
Peptides
Cell Cycle

Plasmon-Activated Water Reduces Amyloid Burden and Improves Memory in Animals with Alzheimer’s Disease

Cheng, C. H., Lin, K. J., Hong, C. T., Wu, D., Chang, H. M., Liu, C. H., Hsiao, I. T., Yang, C. P., Liu, Y. C. & Hu, C. J., Dec 1 2019, In : Scientific Reports. 9, 1, 13252.

Research output: Contribution to journalArticle

Open Access
Amyloid
Alzheimer Disease
Water
Amyloidogenic Proteins
Dementia
3 Citations (Scopus)

Pomalidomide ameliorates H2O2-induced oxidative stress injury and cell death in rat primary cortical neuronal cultures by inducing anti-oxidative and anti-apoptosis effects

Tsai, Y. R., Chang, C. F., Lai, J. H., Wu, J. C. C., Chen, Y. H., Kang, S. J., Hoffer, B. J., Tweedie, D., Luo, W., Greig, N. H., Chiang, Y. H. & Chen, K. Y., Oct 19 2018, In : International Journal of Molecular Sciences. 19, 10

Research output: Contribution to journalArticle

Oxidative stress
apoptosis
Cell death
Cell culture
death
15 Citations (Scopus)

Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat

Wang, J-Y., Huang, Y-N., Chiu, C-C., Tweedie, D., Luo, W-M., Pick, C. G., Chou, S-Y., Luo, Y., Hoffer, B. J., Greig, N. H. & Wang, J. Y., Jun 28 2016, In : Journal of Neuroinflammation. 13, 1, 168.

Research output: Contribution to journalArticle

Glutamic Acid
Wounds and Injuries
Apoptosis
Cytokines
Traumatic Brain Injury
1 Citation (Scopus)

Pomalidomide Reduces Ischemic Brain Injury in Rodents

Tsai, Y. R., Tweedie, D., Navas-Enamorado, I., Scerba, M. T., Chang, C. F., Lai, J. H., Wu, J. C. C., Chen, Y. H., Kang, S. J., Hoffer, B. J., de Cabo, R., Greig, N. H., Chiang, Y. H. & Chen, K. Y., Apr 1 2019, In : Cell Transplantation. 28, 4, p. 439-450 12 p.

Research output: Contribution to journalArticle

Open Access
Brain Injuries
Rodentia
Brain
Rats
Surface active agents
12 Citations (Scopus)

Population-based 5-year follow-up study in taiwan of osteoporosis and risk of periodontitis

Chang, W. P., Chang, W-C., Wu, M. S., Pai, J. T., Guo, Y. C., Chen, K-C., Liu, M. E., Chiu, W-T. & Hung, K-S., 2014, In : Journal of Periodontology. 85, 3

Research output: Contribution to journalArticle

Periodontitis
Taiwan
Osteoporosis
Population
Cohort Studies
10 Citations (Scopus)

Positive feedback regulation between IL10 and EGFR promotes lung cancer formation

Hsu, T. I., Wang, Y. C., Hung, C. Y., Yu, C. H., Su, W. C., Chang, W. C. & Hung, J. J., Apr 12 2016, In : Oncotarget. 7, 15, p. 20840-20854 15 p.

Research output: Contribution to journalArticle

Interleukin-10
Lung Neoplasms
Neoplasms
Carcinogenesis
Lung
13 Citations (Scopus)

Postnatal systemic inflammation exacerbates impairment of hippocampal synaptic plasticity in an animal seizure model

Chen, Y. H., Kuo, T. T., Chu, M. T., Ma, H. I., Chiang, Y. H. & Huang, E. Y. K., Jun 2013, In : NeuroImmunoModulation. 20, 4, p. 223-232 10 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Seizures
Animal Models
Lipopolysaccharides
Inflammation
1 Citation (Scopus)
Brain Concussion
Dizziness
Brain
Equipment and Supplies
Postural Balance

Potential therapeutic effect of curcumin, a natural mTOR inhibitor, in tuberous sclerosis complex

Kuo, C. J., Huang, C. C., Chou, S. Y., Lo, Y. C., Kao, T. J., Huang, N. K., Lin, C., Lin, H. C., Lin, H. C. & Lee, Y. C., Feb 15 2019, In : Phytomedicine. 54, p. 132-139 8 p.

Research output: Contribution to journalArticle

Tuberous Sclerosis
Curcumin
Therapeutic Uses
Memory Disorders
Lipids

Pparα deficiency inhibits the proliferation of neuronal and glial precursors in the zebrafish central nervous system

Hsieh, Y. C., Chiang, M. C., Huang, Y. C., Yeh, T. H., Shih, H. Y., Liu, H. F., Chen, H. Y., Wang, C. P. & Cheng, Y. C., Dec 1 2018, In : Developmental Dynamics. 247, 12, p. 1264-1275 12 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Zebrafish
Neuroglia
Central Nervous System
Brain Neoplasms
1 Citation (Scopus)

Prevalence and clinical characteristics of stroke patients with p.R544C NOTCH3 mutation in Taiwan

Tang, S. C., Chen, Y. R., Chi, N. F., Chen, C. H., Cheng, Y. W., Hsieh, F. I., Hsieh, Y. C., Yeh, H. L., Sung, P. S., Hu, C. J., Chern, C. M., Lin, H. J., Lien, L. M., Peng, G. S., Chiou, H. Y. & Jeng, J. S., Jan 1 2019, In : Annals of Clinical and Translational Neurology. 6, 1, p. 121-128 8 p.

Research output: Contribution to journalArticle

Taiwan
Stroke
Mutation
Cerebral Hemorrhage
CADASIL
7 Citations (Scopus)

Prevalence of intestinal parasitic infections among primary school children in areas devoid of sanitation in northwestern Kingdom of Swaziland, Southern Africa

Fan, C. K., Liao, C. W., Lyu, S. Y., Sukati, H., Ji, D. D., Cho, C. M., Jien, J. Y., Huang, Y. C., Chang, W. S. P., Chiu, W. T., Nara, T., Tsubouchi, A., Huang, Y. H., Tu, C. C., Lan, S. J. & Chao, J. C. J., Mar 2012, In : Pathogens and Global Health. 106, 1, p. 60-62 3 p.

Research output: Contribution to journalArticle

Parasitic Intestinal Diseases
Swaziland
Protozoan Infections
Southern Africa
Parasitic Diseases
5 Citations (Scopus)

Prevalence of Schistosoma haematobium infection among inhabitants of Lowveld, Swaziland, an endemic area for the disease

Chu, T. B., Liao, C. W., D'Lamini, P., Chang, P. W. S., Chiu, W. T., Du, W. Y. & Fan, C. K., 2010, In : Tropical Biomedicine. 27, 2, p. 337-342 6 p.

Research output: Contribution to journalArticle

Swaziland
Schistosoma haematobium
Endemic Diseases
Age Groups
Infection
4 Citations (Scopus)

Prevalence of schistosoma haematobium infection among schoolchildren in remote areas devoid of sanitation in Northwestern Swaziland, Southern Africa

Liao, C. W., Sukati, H., Nara, T., Tsubouchi, A., Chou, C. M., Jian, J. Y., Huang, Y. C., Chang, P. W. S., Chiu, W. T., Huang, Y. H. & Fan, C. K., 2011, In : Japanese Journal of Infectious Diseases. 64, 4, p. 322-326 5 p.

Research output: Contribution to journalArticle

Swaziland
Schistosoma haematobium
Southern Africa
Sanitation
Infection
2 Citations (Scopus)

Primary Central Nervous System Lymphomas of the Brain: A Retrospective Analysis in a Single Institution

Lin, T. K., Yeh, T. H., Hsu, P. W., Chuang, C. C., Tu, P. H., Chen, P. Y., Jung, S. M., Wei, K. C. & Huang, Y. C., Jul 1 2017, In : World Neurosurgery. 103, p. 550-556 7 p.

Research output: Contribution to journalArticle

Lymphoma
Central Nervous System
Brain
Biopsy
Methotrexate
3 Citations (Scopus)

Profound deficits in hippocampal synaptic plasticity after traumatic brain injury and seizure is ameliorated by prophylactic levetiracetam

Chen, Y. H., Kuo, T. T., Huang, E. Y. K., Hoffer, B. J., Chou, Y. C., Chiang, Y. H., Ma, H. I. & Miller, J. P., Feb 20 2018, In : Oncotarget. 9, 14, p. 11515-11527 13 p.

Research output: Contribution to journalArticle

etiracetam
Neuronal Plasticity
Seizures
Percussion
Hippocampus

Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons

Lin, H. C., Ching, Y. H., Huang, C. C., Pao, P. C., Lee, Y. H., Chang, W. C., Kao, T. J. & Lee, Y. C., Apr 26 2019, In : Journal of Biomedical Science. 26, 1, 30.

Research output: Contribution to journalArticle

Open Access
Zinc Fingers
Neurons
Zinc
Leukemia
Brain
2 Citations (Scopus)

Prototype Deep Brain Stimulation System with Closed-Loop Control Feedback for Modulating Bladder Functions in Traumatic Brain Injured Animals

Jen, E., Lin, C. W., Hsieh, T. H., Chiu, Y. C., Lu, T. C., Chen, S. C., Chen, M. C. & Peng, C. W., Jun 1 2018, In : Journal of Medical and Biological Engineering. 38, 3, p. 337-349 13 p.

Research output: Contribution to journalArticle

Feedback control
Brain
Animals
Feedback
Surface mount technology
1 Citation (Scopus)
Brain Concussion
Psychometrics
Longitudinal Studies
Sleep
Anxiety
78 Citations (Scopus)

Quality of life after traumatic brain injury: The clinical use of the QOLIBRI, a novel disease-specific instrument

The QOLIBRI Task Force, Oct 1 2010, In : Brain Injury. 24, 11, p. 1272-1291 20 p.

Research output: Contribution to journalArticle

Health Status
Mental Health
Quality of Life
Diagnostic Self Evaluation
Cognition
17 Citations (Scopus)
Hematoma, Subdural, Chronic
Recurrence
Brain
Hematoma
Tomography

Reconstructive neurosurgery. Preface.

Chiu, W. T. & Chiang, Y. H., 2008, In : Acta Neurochirurgica, Supplementum. 101

Research output: Contribution to journalArticle

Reconstructive Surgical Procedures
Group Processes
Neurosurgery
8 Citations (Scopus)

Reduced power spectra of heart rate variability are correlated with anxiety in patients with mild traumatic brain injury

Liao, K-H., Sung, C-W., Chu, S-F., Chiu, W-T., Chiang, Y-H., Hoffer, B., Ou, J-C., Chen, K-Y., Tsai, S-H., Lin, C-M., Chen, G-S., Li, W-J. & Wang, J-Y., Sep 30 2016, In : Psychiatry Research. 243, p. 349-56 8 p.

Research output: Contribution to journalArticle

Brain Concussion
Anxiety
Heart Rate
Autonomic Nervous System
Healthy Volunteers
12 Citations (Scopus)
Communication
Anisotropy
Interpersonal Relations
Autism Spectrum Disorder
Child Psychology
16 Citations (Scopus)

Relationship of mechanical impact magnitude to neurologic dysfunction severity in a rat traumatic brain injury model

Hsieh, T. H., Kang, J. W., Lai, J. H., Huang, Y. Z., Rotenberg, A., Chen, K. Y., Wang, J. Y., Chan, S. Y., Chen, S. C., Chiang, Y. H. & Peng, C. W., May 1 2017, In : PLoS One. 12, 5, e0178186.

Research output: Contribution to journalArticle

Brain models
Neurologic Manifestations
nervous system
Rats
Brain
17 Citations (Scopus)

Remote effects on the striatal dopamine system after fluid percussion injury

Huang, E. Y. K., Tsai, T. H., Kuo, T. T., Tsai, J. J., Tsui, P. F., Chou, Y. C., Ma, H. I., Chiang, Y. H. & Chen, Y. H., Jul 1 2014, In : Behavioural Brain Research. 267, p. 156-172 17 p.

Research output: Contribution to journalArticle

Percussion
Corpus Striatum
Dopamine
Wounds and Injuries
Brain
4 Citations (Scopus)
Diskectomy
Taiwan
Reoperation
Cohort Studies
Population
4 Citations (Scopus)
Acid Sensing Ion Channels
Radiculopathy
Pain
Research
Spinal Nerve Roots
6 Citations (Scopus)

Resveratrol inhibits human leiomyoma cell proliferation via crosstalk between integrin αvβ3 and IGF-1R

Ho, Y., SH Yang, Y. C., Chin, Y. T., Chou, S. Y., Chen, Y. R., Shih, Y. J., Whang-Peng, J., Changou, C. A., Liu, H. L., Lin, S. J., Tang, H. Y., Lin, H. Y. & Davis, P. J., Oct 1 2018, In : Food and Chemical Toxicology. 120, p. 346-355 10 p.

Research output: Contribution to journalArticle

resveratrol
integrins
Myoma
Cell proliferation
somatomedins

RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription

Yang, C. P., Kuo, Y. L., Lee, Y. C., Lee, K. H., Chiang, C. W., Wang, J. M., Hsu, C. C., Chang, W. C. & Lin, D. Y., Sep 16 2016, In : Biochemical and Biophysical Research Communications. 478, 2, p. 873-880 8 p.

Research output: Contribution to journalArticle

Transcription
Genes
Proteins
Ribosomal DNA
Ribosomes