The Ph.D. Program for Neural Regenerative Medicine

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output

Article

Frame-based stereotactic deep brain stimulation for parkinson's disease: 12 months outcomes for patients in cross hair versus non-cross hair application groups

Tsai, T. H., Ju, D. T., Yu, Y. L., Tang, C. T., Chou, Y. C., Chiang, Y. H., Lin, S. Z. & Chen, Y. H., 2014, In : Journal of Medical Sciences (Taiwan). 34, 4, p. 166-174 9 p.

Research output: Contribution to journalArticle

Frameless stereotactic deep brain stimulation for parkinson’s disease: A case report and technical note

Lin, C. C., Tsai, T. H., Sung, Y. F., Ju, D. T., Chiang, Y. H. & Chen, Y. H., Sep 1 2014, In : Journal of Medical Sciences (Taiwan). 34, 5, p. 224-234 11 p.

Research output: Contribution to journalArticle

Functional Dopaminergic Neurons in Substantia Nigra are Required for Transcranial Magnetic Stimulation-Induced Motor Plasticity

Hsieh, T., Huang, Y. Z., Rotenberg, A., Pascual-Leone, A., Chiang, Y-H., Wang, J-Y. & Chen, J. J. J., Jul 1 2015, In : Cerebral Cortex. 25, 7, p. 1806-1814 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Gene-Embedded Nanostructural Biotic-Abiotic Optoelectrode Arrays Applied for Synchronous Brain Optogenetics and Neural Signal Recording

Huang, W. C., Chi, H. S., Lee, Y. C., Lo, Y. C., Liu, T. C., Chiang, M. Y., Chen, H. Y., Li, S. J., Chen, Y. Y. & Chen, S. Y., Mar 27 2019, In : ACS Applied Materials and Interfaces. 11, 12, p. 11270-11282 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Gene transfer of IGF1 attenuates hepatocellular apoptosis after bile duct ligation

Pi-Chieh Wang, K., Lee, L. M., Lin, T. J., Sheen-Chen, S. M., Lin, J. W., Chiu, W. T., Wang, C. C. & Hung, K. S., May 15 2011, In : Journal of Surgical Research. 167, 2, p. 237-244 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
50 Citations (Scopus)

Genome-wide studies of verbal declarative memory in nondemented older people: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

Debette, S., Ibrahim Verbaas, C. A., Bressler, J., Schuur, M., Smith, A., Bis, J. C., Davies, G., Wolf, C., Gudnason, V., Chibnik, L. B., Yang, Q., DeStefano, A. L., De Quervain, D. J. F., Srikanth, V., Lahti, J., Grabe, H. J., Smith, J. A., Priebe, L., Yu, L., Karbalai, N. & 105 others, Hayward, C., Wilson, J. F., Campbell, H., Petrovic, K., Fornage, M., Chauhan, G., Yeo, R., Boxall, R., Becker, J., Stegle, O., Mather, K. A., Chouraki, V., Sun, Q., Rose, L. M., Resnick, S., Oldmeadow, C., Kirin, M., Wright, A. F., Jonsdottir, M. K., Au, R., Becker, A., Amin, N., Nalls, M. A., Turner, S. T., Kardia, S. L. R., Oostra, B., Windham, G., Coker, L. H., Zhao, W., Knopman, D. S., Heiss, G., Griswold, M. E., Gottesman, R. F., Vitart, V., Hastie, N. D., Zgaga, L., Rudan, I., Polasek, O., Holliday, E. G., Schofield, P., Choi, S. H., Tanaka, T., An, Y., Perry, R. T., Kennedy, R. E., Sale, M. M., Wang, J., Wadley, V. G., Liewald, D. C., Ridker, P. M., Gow, A. J., Pattie, A., Starr, J. M., Porteous, D., Liu, X., Thomson, R., Armstrong, N. J., Eiriksdottir, G., Assareh, A. A., Kochan, N. A., Widen, E., Palotie, A., Hsieh, Y. C., Eriksson, J. G., Vogler, C., Van Swieten, J. C., Shulman, J. M., Beiser, A., Rotter, J., Schmidt, C. O., Hoffmann, W., Nöthen, M. M., Ferrucci, L., Attia, J., Uitterlinden, A. G., Amouyel, P., Dartigues, J. F., Amieva, H., Räikkönen, K., Garcia, M., Wolf, P. A., Hofman, A., Longstreth, W. T., Psaty, B. M., Boerwinkle, E., DeJager, P. L., Sachdev, P. S., Schmidt, R., Breteler, M., Teumer, A., Lopez, O. L., Cichon, S., Chasman, D. I., Grodstein, F., Müller-Myhsok, B., Tzourio, C., Papassotiropoulos, A., Bennett, D. A., Ikram, M. A., Deary, I. J., Van Duijn, C. M., Launer, L., Fitzpatrick, A. L., Seshadri, S. & Mosley, T. H., 2015, In : Biological Psychiatry. 77, 8, p. 749-763 15 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Glucose-Dependent Insulinotropic Polypeptide Ameliorates Mild Traumatic Brain Injury-Induced Cognitive and Sensorimotor Deficits and Neuroinflammation in Rats

Yu, Y. W., Hsieh, T., Chen, K-Y., Wu, J. C. C., Hoffer, B. J., Greig, N. H., Li, Y., Lai, J. H., Chang, C-F., Lin, J-W., Chen, Y. H., Yang, L-Y. & Chiang, Y-H., May 9 2016, In : Journal of Neurotrauma.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Glucose-dependent insulinotropic polypeptide mitigates 6-OHDA-induced behavioral impairments in Parkinsonian rats

Yu, Y. W., Hsueh, S. C., Lai, J. H., Chen, Y. H., Kang, S. J., Chen, K. Y., Hsieh, T. H., Hoffer, B. J., Li, Y., Greig, N. H. & Chiang, Y. H., Apr 11 2018, In : International Journal of Molecular Sciences. 19, 4, 1153.

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access

Glycogen synthase kinase-3β-mediated CCAAT/enhancer-binding protein delta phosphorylation in astrocytes promotes migration and activation of microglia/macrophages

Ko, C. Y., Wang, W. L., Wang, S. M., Chu, Y. Y., Chang, W. C. & Wang, J. M., Jan 2014, In : Neurobiology of Aging. 35, 1, p. 24-34 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

GT-repeat polymorphism in the heme oxygenase-1 gene promoter and the risk of carotid atherosclerosis related to arsenic exposure

Wu, M. M., Chiou, H. Y., Lee, T. C., Chen, C. L., Hsu, L. I., Wang, Y. H., Huang, W. L., Hsieh, Y. C., Yang, T. Y., Lee, C. Y., Yip, P. K., Wang, C. H., Hsueh, Y. M. & Chen, C. J., 2010, In : Journal of Biomedical Science. 17, 1, 70.

Research output: Contribution to journalArticle

24 Citations (Scopus)
26 Citations (Scopus)

GWAS for executive function and processing speed suggests involvement of the CADM2 gene

Ibrahim-Verbaas, C. A., Bressler, J., Debette, S., Schuur, M., Smith, A. V., Bis, J. C., Davies, G., Trompet, S., Smith, J. A., Wolf, C., Chibnik, L. B., Liu, Y., Vitart, V., Kirin, M., Petrovic, K., Polasek, O., Zgaga, L., Fawns-Ritchie, C., Hoffmann, P., Karjalainen, J. & 106 others, Lahti, J., Llewellyn, D. J., Schmidt, C. O., Mather, K. A., Chouraki, V., Sun, Q., Resnick, S. M., Rose, L. M., Oldmeadow, C., Stewart, M., Smith, B. H., Gudnason, V., Yang, Q., Mirza, S. S., Jukema, J. W., DeJager, P. L., Harris, T. B., Liewald, D. C., Amin, N., Coker, L. H., Stegle, O., Lopez, O. L., Schmidt, R., Teumer, A., Ford, I., Karbalai, N., Becker, J. T., Jonsdottir, M. K., Au, R., Fehrmann, R. S. N., Herms, S., Nalls, M., Zhao, W., Turner, S. T., Yaffe, K., Lohman, K., Van Swieten, J. C., Kardia, S. L. R., Knopman, D. S., Meeks, W. M., Heiss, G., Holliday, E. G., Schofield, P. W., Tanaka, T., Stott, D. J., Wang, J., Ridker, P., Gow, A. J., Pattie, A., Starr, J. M., Hocking, L. J., Armstrong, N. J., McLachlan, S., Shulman, J. M., Pilling, L. C., Eiriksdottir, G., Scott, R. J., Kochan, N. A., Palotie, A., Hsieh, Y. C., Eriksson, J. G., Penman, A., Gottesman, R. F., Oostra, B. A., Yu, L., DeStefano, A. L., Beiser, A., Garcia, M., Rotter, J. I., Nöthen, M. M., Hofman, A., Slagboom, P. E., Westendorp, R. G. J., Buckley, B. M., Wolf, P. A., Uitterlinden, A. G., Psaty, B. M., Grabe, H. J., Bandinelli, S., Chasman, D. I., Grodstein, F., Räikkönen, K., Lambert, J. C., Porteous, D. J., Price, J. F., Sachdev, P. S., Ferrucci, L., Attia, J. R., Rudan, I., Hayward, C., Wright, A. F., Wilson, J. F., Cichon, S., Franke, L., Schmidt, H., Ding, J., De Craen, A. J. M., Fornage, M., Bennett, D. A., Deary, I. J., Ikram, M. A., Launer, L. J., Fitzpatrick, A. L., Seshadri, S., Van Duijn, C. M. & Mosley, T. H., Feb 1 2016, In : Molecular Psychiatry. 21, 2, p. 189-197 9 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Hazard Ratio and Repeat Injury for Dementia in Patients with and Without a History of Traumatic Brain Injury

Chu, S. F., Chiu, W. T., Lin, H. W., Chiang, Y. H. & Liou, T. H., Sep 1 2016, In : Asia-Pacific Journal of Public Health. 28, 6, p. 519-527 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
6 Citations (Scopus)
Open Access
2 Citations (Scopus)

High frequency of multiexonic deletion of the GCH1 gene in a Taiwanese cohort of dopa-response dystonia

Wu-Chou, Y. H., Yeh, T. H., Wang, C. Y., Lin, J. J., Huang, C. C., Chang, H. C., Lai, S. C., Chen, R. S., Weng, Y. H., Huang, C. L. & Lu, C. S., Jun 2010, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153, 4, p. 903-908 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Highly sensitive/selective 3D nanostructured immunoparticle-based interface on a multichannel sensor array for detecting amyloid-beta in Alzheimer's disease

Liu, T. C., Lee, Y. C., Ko, C. Y., Liu, R. S., Ke, C. C., Lo, Y. C., Hong, P. S., Chu, C. Y., Chang, C. W., Wu, P. W., Chen, Y. Y. & Chen, S. Y., Jan 1 2018, In : Theranostics. 8, 15, p. 4210-4225 16 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

HMDB and 5-AzadC combination reverses tumor suppressor CCAAT/enhancer-binding protein delta to strengthen the death of liver cancer cells

Li, C. F., Tsai, H. H., Ko, C. Y., Pan, Y. C., Yen, C. J., Lai, H. Y., Yuh, C. H., Wu, W. C. & Wang, J. M., Nov 1 2015, In : Molecular Cancer Therapeutics. 14, 11, p. 2623-2633 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Hyaluronic acid inhibits the glial scar formation after brain damage with tissue loss in rats

Lin, C. M., Lin, J. W., Chen, Y. C., Shen, H. H., Wei, L., Yeh, Y. S., Chiang, Y. H., Shih, R., Chiu, P. L., Hung, K. S., Yang, L. Y. & Chiu, W. T., Dec 2009, In : Surgical Neurology. 72, SUPPL. 2, p. S50-S54

Research output: Contribution to journalArticle

37 Citations (Scopus)
22 Citations (Scopus)

Hypoxia-Preconditioned Human Umbilical Vein Endothelial Cells Protect Against Neurovascular Damage After Hypoxic Ischemia in Neonatal Brain

Lee, Y. C., Chang, Y. C., Wu, C. C. & Huang, C. C., Feb 19 2018, (Accepted/In press) In : Molecular Neurobiology. p. 1-15 15 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58)

Yang, C. P., Chiang, C. W., Chen, C. H., Lee, Y. C., Wu, M. H., Tsou, Y. H., Yang, Y. S., Chang, W. C. & Lin, D. Y., May 16 2015, In : Journal of Biomedical Science. 22, 1, 33.

Research output: Contribution to journalArticle

6 Citations (Scopus)

IL-18-induced interaction between IMP3 and HuR contributes to COX-2 mRNA stabilization in acute myeloid leukemia

Ko, C. Y., Wang, W. L., Li, C. F., Jeng, Y. M., Chu, Y. Y., Wang, H. Y., Tseng, J. T. & Wang, J. M., Jan 1 2016, In : Journal of Leukocyte Biology. 99, 1, p. 131-141 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Implementation of a motorcycle helmet law in Taiwan and traffic deaths over 18 years

Chiu, W. T., Chu, S. F., Chang, C. K., Lui, T. N. & Chiang, Y. H., Jul 20 2011, In : Journal of the American Medical Association. 306, 3, p. 267-268 2 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Important Roles of Ring Finger Protein 112 in Embryonic Vascular Development and Brain Functions

Tsou, J. H., Yang, Y. C., Pao, P. C., Lin, H. C., Huang, N. K., Lin, S. T., Hsu, K. S., Yeh, C. M., Lee, K. H., Kuo, C. J., Yang, D. M., Lin, J. H., Chang, W. C. & Lee, Y. C., 2017, In : Molecular Neurobiology. p. 1-15 15 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Increase of Zinc Finger Protein 179 in Response to CCAAT/Enhancer Binding Protein Delta Conferring an Antiapoptotic Effect in Astrocytes of Alzheimer’s Disease

Wang, S. M., Lee, Y. C., Ko, C. Y., Lai, M. D., Lin, D. Y., Pao, P. C., Chi, J. Y., Hsiao, Y. W., Liu, T. L. & Wang, J. M., 2014, In : Molecular Neurobiology. 51, 1, p. 370-382 13 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury

Greig, N. H., Tweedie, D., Rachmany, L., Li, Y., Rubovitch, V., Schreiber, S., Chiang, Y. H., Hoffer, B. J., Miller, J., Lahiri, D. K., Sambamurti, K., Becker, R. E. & Pick, C. G., 2014, In : Alzheimer's and Dementia. 10, 1 SUPPL.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Individualized prediction of schizophrenia based on the whole-brain pattern of altered white matter tract integrity

Chen, Y. J., Liu, C. M., Hsu, Y. C., Lo, Y. C., Hwang, T. J., Hwu, H. G., Lin, Y. T. & Tseng, W. Y. I., Jan 1 2018, In : Human Brain Mapping. 39, 1, p. 575-587 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Influence of serotonergic mechanisms on the urine flow rate in male rats

Fan, W. J., Chen, S-C., Hsieh, T., Lai, C-H., Lin, Y-S., Peng, C-W. & Kou, Y. R., Nov 15 2014, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 307, 10, p. R1239-R1250

Research output: Contribution to journalArticle

4 Citations (Scopus)

Infrared thermography to mass-screen suspected sars patients with fever

Chiu, W. T., Lin, P. W., Chiou, H. Y., Lee, W. S., Lee, C. N., Yang, Y. Y., Lee, H. M., Hsieh, M. S., Hu, C. J., Ho, Y. S., Deng, W. P. & Hsu, C. Y., 2005, In : Asia-Pacific Journal of Public Health. 17, 1, p. 26-28 3 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Inhibition of HSP90-dependent telomerase activity in amyloid β-induced apoptosis of cerebral endothelial cells

Chiu, W-T., Shen, S-C., Yang, L-Y., Chow, J-M., Wu, C. Y. & Chen, Y-C., Aug 2011, In : Journal of Cellular Physiology. 226, 8, p. 2041-2051 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

International aeromedical evacuation [23]

Tsai, S-H., Chen, W. L. & Chiu, W-T., Apr 19 2007, In : New England Journal of Medicine. 356, 16, p. 1685 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

International differences in treatment and clinical outcomes for high grade glioma

Chien, L. N., Ostrom, Q. T., Gittleman, H., Lin, J. W., Sloan, A. E., Barnett, G. H., Elder, J. B., McPherson, C., Warnick, R., Chiang, Y. H., Lin, C. M., Rogers, L. R., Chiou, H. Y. & Barnholtz-Sloan, J. S., Jun 10 2015, In : PLoS One. 10, 6, e0129602.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Involvement of autophagy upregulation in 3,4-methylenedioxymethamphetamine ('ecstasy')-induced serotonergic neurotoxicity

Li, I. H., Ma, K. H., Kao, T. J., Lin, Y. Y., Weng, S. J., Yen, T. Y., Chen, L. C. & Huang, Y. S., Jan 1 2016, In : NeuroToxicology. 52, p. 114-126 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Involvement of L-type Ca2+ Channel and Toll-Like Receptor-4 in Nickel-Induced Interleukin-8 Gene Expression

Lin, C. H., Chung, C. A., Wong, J. H., Chen, B. K., Chiu, S. J., Klahan, S., Lee, Y. C. & Chang, W-C., Jan 1 2016, In : Environmental Toxicology. 31, 1, p. 5-12 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Ketamine ameliorates severe traumatic event-induced antidepressant-resistant depression in a rat model through ERK activation

Lee, C. W., Chen, Y. J., Wu, H. F., Chung, Y. J., Lee, Y. C., Li, C. T. & Lin, H. C., Jul 13 2019, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 93, p. 102-113 12 p.

Research output: Contribution to journalArticle

L-Dopa induced dyskinesias in Parkinsonian mice: Disease severity or l-Dopa history

Shan, L., Diaz, O., Zhang, Y., Ladenheim, B., Cadet, J. L., Chiang, Y. H., Olson, L., Hoffer, B. J. & Bäckman, C. M., Aug 27 2015, In : Brain Research. 1618, p. 261-269 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Leukemia Inhibitory Factor Promotes Castration-resistant Prostate Cancer and Neuroendocrine Differentiation by Activated ZBTB46

Liu, Y-N., Niu, S., Chen, W-Y., Zhang, Q., Tao, Y., Chen, W-H., Jiang, K-C., Chen, X., Shi, H., Liu, A., Li, J., Li, Y., Lee, Y-C., Zhang, X. & Huang, J., Apr 8 2019, In : Clinical cancer research : an official journal of the American Association for Cancer Research.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Levetiracetam prophylaxis ameliorates seizure epileptogenesis after fluid percussion injury

Chen, Y. H., Huang, E. Y. K., Kuo, T. T., Hoffer, B. J., Wu, P. J., Ma, H. I., Tsai, J., Chou, Y. C. & Chiang, Y. H., Jul 1 2016, In : Brain Research. 1642, p. 581-589 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

LGK974, a PORCUPINE inhibitor, mitigates cytotoxicity in an in vitro model of Parkinson's disease by interfering with the WNT/β-CATENIN pathway

Yang, J. M., Huang, H. M., Cheng, J. J., Huang, C. L., Lee, Y. C., Chiou, C. T., Huang, H. T., Huang, N. K. & Yang, Y. C., Dec 1 2018, In : Toxicology. 410, p. 65-72 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Live images of GLUT4 protein trafficking in mouse primary hypothalamic neurons using deconvolution microscopy

Changou, C. A., Chou, S. Y. & Ajoy, R., Dec 7 2017, In : Journal of Visualized Experiments. 2017, 130, e56409.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Location and level of Etk expression in neurons are associated with varied severity of traumatic brain injury

Wu, J. C. C., Chen, K. Y., Yu, Y. W., Huang, S. W., Shih, H. M., Chiu, W. T., Chiang, Y. H. & Shiau, C. Y., Jun 18 2012, In : PLoS One. 7, 6, e39226.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Long-term voluntary physical exercise exerts neuroprotective effects and motor disturbance alleviation in a rat model of Parkinson's disease

Tsai, W. L., Chen, H. Y., Huang, Y. Z., Chen, Y. H., Kuo, C. W., Chen, K. Y. & Hsieh, T. H., Jan 1 2019, In : Behavioural Neurology. 2019, 4829572.

Research output: Contribution to journalArticle

Open Access

LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study

International Parkinsonism Genetics Network, Jul 1 2018, In : The Lancet Neurology. 17, 7, p. 597-608 12 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Mapping the naloxone binding sites on the mu-opioid receptor using cell-based photocrosslinkers

Ke, Y. Y., Huang, Y. H., Chien, W. C., Loh, H. H., Chuang, J. Y. & Yeh, S. H., Mar 1 2017, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1865, 3, p. 336-343 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
6 Citations (Scopus)

Medical treatment guidelines for acute migraine attacks

Treatment Guideline Subcommittee of Taiwan Headache Society, Jan 1 2017, In : Acta Neurologica Taiwanica. 26, 2, p. 78-96 19 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)