The Ph.D. Program for Neural Regenerative Medicine

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output

(−)-Phenserine inhibits neuronal apoptosis following ischemia/reperfusion injury

Chang, C. F., Lai, J. H., Wu, J. C. C., Greig, N. H., Becker, R. E., Luo, Y., Chen, Y. H., Kang, S. J., Chiang, Y. H. & Chen, K. Y., Dec 15 2017, In : Brain Research. 1677, p. 118-128 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

(−)-Phenserine tartrate (PhenT) as a treatment for traumatic brain injury

Greig, N. H., Lecca, D., Hsueh, S. C., Nogueras-Ortiz, C., Kapogiannis, D., Tweedie, D., Glotfelty, E. J., Becker, R. E., Chiang, Y. H. & Hoffer, B. J., Jan 1 2019, (Accepted/In press) In : CNS Neuroscience and Therapeutics.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4 H -indazol-4-one: A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine

Chao, P. K., Ueng, S. H., Ou, L. C., Yeh, T. K., Chang, W. T., Chang, H. F., Chen, S. C., Tao, P. L., Law, P. Y., Loh, H. H., Cheng, M. F., Chuang, J. Y., Chen, C. T., Shih, C. & Yeh, S. H., May 1 2017, In : Anesthesiology. 126, 5, p. 952-966 15 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

58-kDa microspherule protein (MSP58) is novel brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway

Hsu, C. C., Lee, Y. C., Yeh, S. H., Chen, C. H., Wu, C. C., Wang, T. Y., Chen, Y. N., Hung, L. Y., Liu, Y. W., Chen, H. K., Hsiao, Y. T., Wang, W. S., Tsou, J. H., Tsou, Y. H., Wu, M. H., Chang, W. C. & Lin, D. Y., Jun 29 2012, In : Journal of Biological Chemistry. 287, 27, p. 22533-22548 16 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Aberrantly expressed AURKC enhances the transformation and tumourigenicity of epithelial cells

Tsou, J. H., Chang, K. C., Chang-Liao, P. Y., Yang, S. T., Lee, C. T., Chen, Y. P., Lee, Y. C., Lin, B. W., Lee, J. C., Shen, M. R., Chuang, C. K., Chang, W. C., Wang, J. M. & Hung, L. Y., Oct 2011, In : Journal of Pathology. 225, 2, p. 243-254 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Accumulation of amyloid in cognitive impairment after mild traumatic brain injury

Yang, S. T., Hsiao, I. T., Hsieh, C. J., Chiang, Y. H., Yen, T. C., Chiu, W. T., Lin, K. J. & Hu, C. J., Feb 15 2015, In : Journal of the Neurological Sciences. 349, 1-2, p. 99-104 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Acta Neurochirurgica, Supplementum: Preface

Chiu, W. T. & Chiang, Y. H., 2008, In : Acta Neurochirurgica, Supplementum. 101

Research output: Contribution to journalArticle

A germline missense mutation in COQ6 is associated with susceptibility to familial schwannomatosis

Zhang, K., Lin, J. W., Wang, J., Wu, X., Gao, H., Hsieh, Y. C., Hwu, P., Liu, Y. R., Su, L., Chiou, H. Y., Wang, D., Yuan, Y. C., Whang-Peng, J., Chiu, W. T. & Yen, Y., Oct 1 2014, In : Genetics in Medicine. 16, 10, p. 787-792 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models

Liu, Y. C., Wang, H. L., Huang, Y. Z., Weng, Y. H., Chen, R. S., Tsai, W. C., Yeh, T. H., Lu, C. S., Chen, Y. L., Lin, Y. W., Chen, Y. J., Hsu, C. C., Chiu, C. H. & Chiu, C. C., May 2020, In : Biochemical Pharmacology. 175, 113919.

Research output: Contribution to journalArticle

Altered frontal aslant tracts as a heritable neural basis of social communication deficits in autism spectrum disorder: A sibling study using tract-based automatic analysis

Lo, Y. C., Chen, Y. J., Hsu, Y. C., Chien, Y. L., Gau, S. S. F. & Tseng, W. Y. I., Feb 1 2019, In : Autism Research. 12, 2, p. 225-238 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Amantadine ameliorates dopamine-releasing deficits and behavioral deficits in rats after fluid percussion injury

Huang, E. Y. K., Tsui, P. F., Kuo, T. T., Tsai, J., Chou, Y. C., Ma, H. I., Chiang, Y. H. & Chen, Y. H., Jan 30 2014, In : PLoS One. 9, 1, e86354.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Analysis of spatial and temporal protein expression in the cerebral cortex after Ischemia-Reperfusion injury

Chen, Y. H., Chiang, Y-H. & Maa, H. I., 2014, In : Journal of Clinical Neurology (Korea). 10, 2, p. 84-93 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Analysis of the interaction between Zinc finger protein 179 (Znf179) and promyelocytic leukemia zinc finger (Plzf)

Lin, D. Y., Huang, C. C., Hsieh, Y. T., Lin, H. C., Pao, P. C., Tsou, J. H., Lai, C. Y., Hung, L. Y., Wang, J. M., Chang, W. C. & Lee, Y. C., Dec 20 2013, In : Journal of Biomedical Science. 20, 1, 98.

Research output: Contribution to journalArticle

15 Citations (Scopus)
10 Citations (Scopus)
Open Access
3 Citations (Scopus)

A novel missense mutation of the GTP cyclohydrolase 1 gene in a Taiwanese family with dopa-responsive dystonia: A case report

Yang, C. C., Wang, W. C., Yeh, T. H., Chen, T. H., Liu, Y. L., Lu, M. K., Lu, C. S. & Tsai, C. H., Feb 1 2018, In : Clinical Neurology and Neurosurgery. 165, p. 21-23 3 p.

Research output: Contribution to journalArticle

A novel RING finger protein, Znf179, modulates cell cycle exit and neuronal differentiation of P19 embryonal carcinoma cells

Pao, P. C., Huang, N. K., Liu, Y. W., Yeh, S. H., Lin, S. T., Hsieh, C. P., Huang, A. M., Huang, H. S., Tseng, J. T., Chang, W. C. & Lee, Y. C., Nov 2011, In : Cell Death and Differentiation. 18, 11, p. 1791-1804 14 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

A polygenic risk score for breast cancer risk in a Taiwanese population

Hsieh, Y. C., Tu, S. H., Su, C. T., Cho, E. C., Wu, C. H., Hsieh, M. C., Lin, S. Y., Liu, Y. R., Hung, C. S. & Chiou, H. Y., May 1 2017, In : Breast Cancer Research and Treatment. 163, 1, p. 131-138 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

A proof-of-principle simulation for closed-loop control based on preexisting experimental thalamic DBS-enhanced instrumental learning

Wang, C. F., Yang, S-H., Lin, S. H., Chen, P. C., Lo, Y. C., Pan, H. C., Lai, H. Y., Liao, L. D., Lin, C. H., Chen, H. Y., Huang, W. C., Huang, W. J. & Chen, Y. Y., May 1 2017, In : Brain Stimulation. 10, 3, p. 672-683 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

A prospective randomized study of brain tissue oxygen pressure-guided management in moderate and severe traumatic brain injury patients

Lin, C. M., Lin, M. C., Huang, S. J., Chang, C. K., Chao, D. P., Lui, T. N., Ma, H. I., Liu, M. Y., Chung, W. Y., Shih, Y. H., Tsai, S. H., Chiou, H. Y., Lin, M. R., Jen, S. L., Wei, L., Wu, C-C., Lin, E. Y., Liao, K. H., Chiang, Y. H., Chiu, W. T. & 1 others, Lin, J. W., 2015, In : BioMed Research International. 2015, 529580.

Research output: Contribution to journalArticle

14 Citations (Scopus)

A rapid and quantitative method to detect human circulating tumor cells in a preclinical animal model

Tu, S. H., Hsieh, Y. C., Huang, L. C., Lin, C. Y., Hsu, K. W., Hsieh, W. S., Chi, W. M. & Lee, C. H., Jun 23 2017, In : BMC Cancer. 17, 1, 440.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Arsenic exposure and cerebrovascular disease

Chiou, H. Y. & Hsieh, Y. C., Jan 1 2011, Health Hazards of Arsenic Poisoning Environmental: From Epidemic to Pandemic. World Scientific Publishing Co., p. 123-134 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox homeostasis

Chen, T. C., Chuang, J. Y., Ko, C. Y., Kao, T. J., Yang, P. Y., Yu, C. H., Liu, M. S., Hu, S. L., Tsai, Y. T., Chan, H., Chang, W. C. & Hsu, T. I., Feb 1 2020, In : Redox Biology. 30, p. 101413 101413.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Asia Pacific Academic Consortium for Public Health APACPH Public Health Recognition Award.

Chiu, W. T. & Patrick, W. K., Apr 2010, In : Asia-Pacific Journal of Public Health. 22, 2, p. 256-257 2 p.

Research output: Contribution to journalArticle

A significant decrease in blood pressure through a family-based nutrition health education programme among community residents in Taiwan

Hsieh, Y. C., Hung, C. T., Lien, L. M., Bai, C. H., Chen, W. H., Yeh, C. Y., Chen, Y. H., Hsieh, F. I., Chiu, H. C., Chiou, H. Y. & Hsu, C. Y., Apr 2009, In : Public Health Nutrition. 12, 4, p. 570-577 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

A sliced inverse regression (SIR) decoding the forelimb movement from neuronal spikes in the rat motor cortex

Yang, S-H., Chen, Y. Y., Lin, S. H., Liao, L. D., Lu, H. H. S., Wang, C. F., Chen, P. C., Lo, Y. C., Phan, T. D., Chao, H. Y., Lin, C. H., Lai, H. Y. & Huang, W. C., 2016, In : Frontiers in Neuroscience. 10, DEC, 556.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Aspirin better than clopidogrel on major adverse cardiovascular events reduction after ischemic stroke: A retrospective nationwide cohort study

Vidyanti, A. N., Chan, L., Lin, C. L., Muo, C. H., Hsu, C. Y., Chen, Y. C., Wu, D. & Hu, C. J., Jan 1 2019, In : PLoS ONE. 14, 8, e0221750.

Research output: Contribution to journalArticle

Open Access
Open Access

Association between Anemia and Dementia-A Nationwide, Population-Based Cohort Study in Taiwan

Hong, C-T., Hsieh, Y-C., Liu, H-Y., Chiou, H-Y. & Chien, L-N., Mar 17 2020, In : Current Alzheimer Research. 17, 2, p. 196-204 9 p.

Research output: Contribution to journalArticle

Association between genetic variant on chromosome 12p13 and stroke survival and recurrence: A one year prospective study in Taiwan

Hsieh, Y. C., Seshadri, S., Chung, W. T., Hsieh, F. I., Hsu, Y. H., Lin, H. J., Tseng, H. P., Lien, L. M., Bai, C. H., Hu, C. J., Jeng, J. S., Tang, S. C., Chen, C. I., Yu, C. C. & Chiou, H. Y., 2012, In : Journal of Biomedical Science. 19, 1, 1.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Association of Antiviral Therapy with Risk of Parkinson Disease in Patients with Chronic Hepatitis C Virus Infection

Lin, W. Y., Lin, M. S., Weng, Y. H., Yeh, T. H., Lin, Y. S., Fong, P. Y., Wu, Y. R., Lu, C. S., Chen, R. S. & Huang, Y. Z., Sep 2019, In : JAMA Neurology. 76, 9, p. 1019-1027 9 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Association of blood active matrix metalloproteinase-3 with carotid plaque score from a community population in Taiwan

Lien, L. M., Hsieh, Y. C., Bai, C. H., Chen, W-H., Chiu, H. C., Hsieh, F. I., Shyu, K-G., Chiou, H. Y. & Hsu, C-Y., Oct 2010, In : Atherosclerosis. 212, 2, p. 595-600 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Association of estrogen receptor ± genotypes/ haplotypes with carotid intima-media thickness in taiwanese women

Wu, M. M., Hsieh, Y. C., Lien, L. M., Chen, W. H., Bai, C. H., Chiu, H. C., Chen, H. H., Chung, W. T., Lee, Y. C., Hsu, C. Y., Lin, H. W. & Chiou, H. Y., Jun 2010, In : Angiology. 61, 3, p. 275-282 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
20 Citations (Scopus)

Associations of birth outcomes with air pollution and land use characteristics in the Greater Taipei Area

Santri, I. N., Jiang, C. B., Chen, Y. H., Wu, C. D., Zou, M. L., Chien, L. C., Lo, Y. C. & Chao, H. J., Jan 1 2021, In : Science of the Total Environment. 750, 141579.

Research output: Contribution to journalArticle

Associations of estradiol levels and genetic polymorphisms of inflammatory genes with the risk of ischemic stroke

Hsieh, Y. C., Hsieh, F. I., Chen, Y. R., Hu, C. J., Jeng, J. S., Tang, S. C., Chi, N. F., Lin, H. J., Lien, L. M., Peng, G. S. & Chiou, H. Y., Mar 28 2017, In : Journal of Biomedical Science. 24, 1, 25.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury

Wang, S. M., Hsu, J. Y. C., Ko, C. Y., Chiu, N. E., Kan, W. M., Lai, M. D. & Wang, J. M., Nov 1 2016, In : Molecular Neurobiology. 53, 9, p. 5912-5927

Research output: Contribution to journalArticle

8 Citations (Scopus)

Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation

Wang, S. M., Lim, S. W., Wang, Y. H., Lin, H. Y., Lai, M. D., Ko, C. Y. & Wang, J. M., Jun 1 2018, In : Redox Biology. 16, p. 104-112 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Astrocytic CCAAT/Enhancer Binding Protein δ Regulates Neuronal Viability and Spatial Learning Ability via miR-135a

Chu, Y. Y., Ko, C. Y., Wang, W. J., Wang, S. M., Gean, P. W., Kuo, Y. M. & Wang, J. M., 2016, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

11 Citations (Scopus)

BAI1-Associated Protein 2-Like 1 (BAIAP2L1) Is a potential biomarker in ovarian cancer

Chao, A., Tsai, C. L., Jung, S. M., Chuang, W. C., Kao, C., Hsu, A., Chen, S. H., Lin, C. Y., Lee, Y. C., Lee, Y. S., Wang, T. H., Wang, H. S. & Lai, C. H., Jul 29 2015, In : PLoS One. 10, 7, e0133081.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Balance function and sensory integration after mild traumatic brain injury

Lin, L. F., Liou, T. H., Hu, C. J., Ma, H. P., Ou, J. C., Chiang, Y. H., Chiu, W. T., Tsai, S. H. & Chu, W. C., Jan 1 2015, In : Brain Injury. 29, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
39 Citations (Scopus)
10 Citations (Scopus)

Betulinic acid-mediated tuning of PERK/CHOP signaling by sp1 inhibition as a novel therapeutic strategy for glioblastoma

Lo, W. L., Hsu, T. I., Yang, W. B., Kao, T. J., Wu, M. H., Huang, Y. N., Yeh, S. H. & Chuang, J. Y., Apr 2020, In : Cancers. 12, 4, 981.

Research output: Contribution to journalArticle

Open Access

Biochemical alteration in cerebrospinal fluid precedes behavioral deficits in Parkinsonian rats induced by 6-hydroxydopamine

Lin, J-W., Shih, C-M., Chen, Y-C., Lin, C-M., Tsai, J-T., Chiang, Y-H., Shih, R., Chiu, P. L., Hung, K-S., Yeh, Y. S., Wei, L., Chiu, W-T. & Yang, L-Y., Dec 2009, In : Surgical Neurology. 72, SUPPL. 2, p. S55-S65

Research output: Contribution to journalArticle

1 Citation (Scopus)

Biological roles of CCAAT/enhancer-binding protein delta during inflammation

Ko, C. Y., Chang, W. C. & Wang, J. M., Jan 16 2015, In : Journal of Biomedical Science. 22, 1, 6.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Blockade of dengue virus infection and viral cytotoxicity in neuronal cells in vitro and in vivo by targeting endocytic pathways

Ho, M. R., Tsai, T. T., Chen, C. L., Jhan, M. K., Tsai, C. C., Lee, Y. C., Chen, C. H. & Lin, C. F., Dec 1 2017, In : Scientific Reports. 7, 1, 7023.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Bortezomib-induced miRNAs direct epigenetic silencing of locus genes and trigger apoptosis in leukemia

Chu, Y. Y., Ko, C. Y., Wang, S. M., Lin, P. I., Wang, H. Y., Lin, W. C., Wu, D. Y., Wang, L. H. & Wang, J. M., Nov 9 2017, In : Cell death & disease. 8, 11, p. e3167

Research output: Contribution to journalArticle

5 Citations (Scopus)

BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine

Chao, P. K., Chang, H. F., Chang, W. T., Yeh, T. K., Ou, L. C., Chuang, J. Y., Tsu-An Hsu, J., Tao, P. L., Loh, H. H., Shih, C., Ueng, S. H. & Yeh, S. H., Apr 1 2020, In : Neuropharmacology. 166, 107678.

Research output: Contribution to journalArticle

3 Citations (Scopus)

C9orf72 is essential for neurodevelopment and motility mediated by Cyclin G1

Yeh, T. H., Liu, H. F., Li, Y. W., Lu, C. S., Shih, H. Y., Chiu, C. C., Lin, S. J., Huang, Y. C. & Cheng, Y. C., Jun 1 2018, In : Experimental Neurology. 304, p. 114-124 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)